1. Stephen A. Boppart

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    1. Mentioned In 185 Articles

    2. Caries Detection Using Light-Based Diagnostic Tool

      Caries Detection Using Light-Based Diagnostic Tool
      Modern caries treatment concepts like caries management by risk assessmentCAMBRAentail diagnosing early caries lesions in a precavitated stage to make it possible to reverse the caries process with remineralization and bacteria reduction efforts. Newer, sensitive caries diagnostic tools can serve not only for early detection but also for monitoring of caries lesions to confirm the success of prevention and remineralization efforts. This article describes light-based caries diagnostic tools, with emphasis ...
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    3. Segmentation, co-registration, and correlation of optical coherence tomography and X-ray images for breast cancer diagnostics (Thesis)

      Segmentation, co-registration, and correlation of optical coherence tomography and X-ray images for breast cancer diagnostics (Thesis)
      In this thesis, x-ray imaging is evaluated and compared with optical coherence tomography (OCT). It is shown that each individual modality provides information about a sample through different physical characteristics. The preclinical variant of x-ray imaging is explored in the context of breast cancer detection and diagnosis because their clinical use could be augmented by OCT. After comparing them, each modality showed its specialized usage. Micro-CT is useful in detecting ...
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    4. University of Illinois Urbana-Champaign received NIH Grant for Developing an Intraoperative Label-Free Optical Molecular Imaging of Breast Tumor Margins

      University of Illinois Urbana-Champaign received NIH Grant for Developing an Intraoperative Label-Free Optical Molecular Imaging of Breast Tumor Margins
      ...gins. The program is a multi-year program and started in 2012 and ends in 2017. The principle investigator is Stephen Boppart. A brief description of the project is given below. Margin status during the surgical treatme...
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    5. University of Illinois at Urbana-Champaign Wins NIH Grant for Developing Technology for Primary Care Imaging

      University of Illinois at Urbana-Champaign Wins NIH Grant for Developing Technology for Primary Care Imaging
      ...The program is part of a multiyear study that started in 2011 and ends in 2016. The principal investigator is Stephen Boppart. Below is a summary of the proposed work.  Primary Care Medicine, including Family Practice a...
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    6. University of Illinois at Urbana-Champaign Wins NIH Grant for Investigating Targeted Microspheres for Contract Enhancement in Optical Coherence Tomography.

      University of Illinois at Urbana-Champaign Wins NIH Grant for Investigating Targeted Microspheres for Contract Enhancement in Optical Coherence Tomography.
      ... in Optical Coherence Tomography. The program started in 2009 and ends in 2013. The principal investigator is Stephen Boppart. Below is a summary of the proposed work.  Molecular imaging is frequently performed with con...
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    7. Group refractive index reconstruction with broadband interferometric confocal microscopy

      Group refractive index reconstruction with broadband interferometric confocal microscopy
      A system and method for microscale measurement and imaging of the group refractive index of a sample. The method utilizes a broadband confocal high-numerical aperture microscope embedded into an interferometer and a spectrometric means, whereby spectral interferograms are analyzed to compute optical path delay of the beam traversing the sample as the sample is translated through the focus of an interrogating light beam. A determination of group refractive index may ...
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    8. Three-dimensional Optical Coherence Tomography for Optical Biopsy of Lymph Nodes and Assessment of Metastatic Disease

      Three-dimensional Optical Coherence Tomography for Optical Biopsy of Lymph Nodes and Assessment of Metastatic Disease
      ...sease Renu John PhD, Steven G. Adie PhD, Eric J. Chaney BS, Marina Marjanovic PhD, Krishnarao V. Tangella MD, Stephen A. Boppart MD, PhD Translational Research and Biomarkers Online First ™ - June , 2012 View full articl...
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    9. Feature Of The Week 6/10/12: Computational Adaptive Optics: A New Digital Post-Processing Technique to Optimize Resolution in OCT and other Interferometric Optical Imaging Applications

      Feature Of The Week 6/10/12: Computational Adaptive Optics: A New Digital Post-Processing Technique to Optimize Resolution in OCT and other Interferometric Optical Imaging Applications
      ...volume spanning tens of Rayleigh lengths.For more information see recent Article. Courtesy of Steven Adie and Stephen Boppart from the University of Illinois at Urbana-Champaign. To share this article click Here.Referenc...
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    10. Noninvasive in vivo optical detection of biofilm in the human middle ear

      Noninvasive in vivo optical detection of biofilm in the human middle ear
      Otitis media (OM), a middle-ear infection, is the most common childhood illness treated by pediatricians. If inadequately treated, OM can result in long-term chronic problems persisting into adulthood. Children with chronic OM or recurrent OM often have conductive hearing loss and communication difficulties and require surgical treatment. Tympanostomy tube insertion, the placement of a small drainage tube in the tympanic membrane (TM), is the most common surgical procedure performed in ...
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    11. Computational adaptive optics for broadband optical interferometric tomography of biological tissue

      Computational adaptive optics for broadband optical interferometric tomography of biological tissue
      Aberrations in optical microscopy reduce image resolution and contrast, and can limit imaging depth when focusing into biological samples. Static correction of aberrations may be achieved through appropriate lens design, but this approach does not offer the flexibility of simultaneously correcting aberrations for all imaging depths, nor the adaptability to correct for sample-specific aberrations for high-quality tomographic optical imaging. Incorporation of adaptive optics (AO) methods have demonstrated considerable improvement in ...
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    12. 61-75 of 185 « 1 2 3 4 5 6 7 8 ... 11 12 13 »
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  2. About Stephen A. Boppart

    Stephen A. Boppart

    Stephen A. Boppart is a professor in the Biophotonics Imaging Laboratory at the University of Illinois Urbana Champaign.  Dr. Boppart received his Ph.D. from the Massachusetts Institute of Technology in 1998, followed by a M.D. from Harvard Medical School in 2000. Currently Prof. Boppart is a full-time faculty member in the Beckman Institute Nanoelectronics and Biophotonics Group as well as an associate professor in the UIUC Department of Electrical and Computer Engineering and the Bioengineering Department. In January 2007, he was named the Founding Director of the Mills Breast Cancer Institute at Carle Foundation Hospital. Dr. Boppart is also a Clinical Research Physician in the UI College of Medicine-Urbana. His fields of professional interest include optical imaging (specifically in Optical Coherence Tomography) and biophotonics in medicine and biology.

  3. Quotes

    1. Any state of disease will alter the cells and molecules in our body...leaving a distinct optical scattering signature.” The new device senses cancer cells’ unique signatures, letting surgeons know which areas around the tumor are cancerous and which are safe to leave alone.
      In Flashlight-Sized Probe Can Spot Cancer Cells in Real Time
    2. We agree that, given the images we've seen from the hardware [adaptive optics] systems, our computational approaches are equivalent to those...In addition, we think we could do better by correcting the finer aberrations and by being able to manipulate the data post-acquisition, which gives us a lot more flexibility.
      In Bringing the human eye into focus
    3. We agree that, given the images we've seen from the hardware [adaptive optics] systems, our computational approaches are equivalent to those...In addition, we think we could do better by correcting the finer aberrations and by being able to manipulate the data post-acquisition, which gives us a lot more flexibility.
      In Bringing the human eye into focus
    4. Jim's innovation, scholarly activities, professional service, entrepreneurial efforts, and impact on the field of biomedical optics typifies the spirit of this award, and reflects the seminal changes that Britton Chance made during his lifetime...Few researchers in the world today have had such a profound impact as a result of their technological work that has literally changed our field, changed the way we practice medicine, and directly improved the lives of perhaps hundreds of thousands of patients (considering ophthalmology and cardiology).
      In Fujimoto Honored with Britton Chance Biomedical Optics Award
    5. We know that antibiotics don’t always work well if you have a biofilm, because the bacteria protect themselves and become resistant...In the presence of a chronic ear infection that has a biofilm, the bacteria may not respond to the usual antibiotics, and you need to stop them. But without being able to detect the biofilm, we have no idea whether or not it’s responding to treatment.
      In Nowhere to hide: New device sees bacteria behind the eardrum
    6. I think it's going to dramatically change things...What we hope is that diagnosis is going to get shifted closer and closer to the point of care...We’re developing techniques to get at molecular changes..So much of medicine and pathology are based on structural changes. If we think of a pathologist looking at a slide, he or she looks at the cells and tissue structures. A radiologist will look at how organs and these anatomical structures are arranged...But with a lot of these techniques, we can get the molecular changes where disease starts. So a pathologist that has molecular information, not just structural, will perhaps catch disease earlier. The same is true for Rohit’s work and Gabi’s work.
      In Positive Results: A New Era for Medical Diagnostics - News from UIUC
    7. It's the same challenge, but instead of imaging through the atmosphere, we're imaging through tissue, and instead of imaging a star, we're imaging a cell.
      In Computing the best high-resolution 3-D tissue images - News from Beckman Institute at UIUC
    8. The effectiveness is striking...Because of the aberrations of the human eye, when you look at the retina without adaptive optics you just see variations of light and dark areas that represent the rods and cones. But when you use adaptive optics, you see the rods and cones as distinct objects...are working to compute the best image possible.
      In Computing the best high-resolution 3-D tissue images - News from Beckman Institute at UIUC
    9. to emphasize the role of medical imaging and how this technology has enabled us to look into the body at many different size scales, how imaging has enabled us to diagnose disease, and how imaging has made a difference in our healthcare...Federal dollars have been used to fund technology that’s going to change and improve health care. They already have. In the area of optics and high-resolution optical imaging, there’s going to be better healthcare, economic development with new companies, new jobs, and new areas of research to investigate...We can now do real-time microscopic imaging in the operating room without waiting for pathology.
      In Boppart Presents at Congressional Briefing
    10. In the end, I expect the cost of this system will be slightly more than what it replaces, but with significantly more capabilities, I do expect the cost of this system to continue to fall as more systems are developed and demand increases...This will be a boon for poorer hospitals and Third World or developing countries...It is essentially a portable imaging system with digital data that can be sent via cell-phone networks for analysis by experts in larger cities/hospitals.
      In Scientists awarded grant to continue developing optical device for medical exams