1. About Stephen A. Boppart

    Stephen A. Boppart

    Stephen A. Boppart is a professor in the Biophotonics Imaging Laboratory at the University of Illinois Urbana Champaign.  Dr. Boppart received his Ph.D. from the Massachusetts Institute of Technology in 1998, followed by a M.D. from Harvard Medical School in 2000. Currently Prof. Boppart is a full-time faculty member in the Beckman Institute Nanoelectronics and Biophotonics Group as well as an associate professor in the UIUC Department of Electrical and Computer Engineering and the Bioengineering Department. In January 2007, he was named the Founding Director of the Mills Breast Cancer Institute at Carle Foundation Hospital. Dr. Boppart is also a Clinical Research Physician in the UI College of Medicine-Urbana. His fields of professional interest include optical imaging (specifically in Optical Coherence Tomography) and biophotonics in medicine and biology.

  2. Quotes

    1. I think it's going to dramatically change things...What we hope is that diagnosis is going to get shifted closer and closer to the point of care...We’re developing techniques to get at molecular changes..So much of medicine and pathology are based on structural changes. If we think of a pathologist looking at a slide, he or she looks at the cells and tissue structures. A radiologist will look at how organs and these anatomical structures are arranged...But with a lot of these techniques, we can get the molecular changes where disease starts. So a pathologist that has molecular information, not just structural, will perhaps catch disease earlier. The same is true for Rohit’s work and Gabi’s work.
      In Positive Results: A New Era for Medical Diagnostics - News from UIUC
    2. It's the same challenge, but instead of imaging through the atmosphere, we're imaging through tissue, and instead of imaging a star, we're imaging a cell.
      In Computing the best high-resolution 3-D tissue images - News from Beckman Institute at UIUC
    3. The effectiveness is striking...Because of the aberrations of the human eye, when you look at the retina without adaptive optics you just see variations of light and dark areas that represent the rods and cones. But when you use adaptive optics, you see the rods and cones as distinct objects...are working to compute the best image possible.
      In Computing the best high-resolution 3-D tissue images - News from Beckman Institute at UIUC
    4. to emphasize the role of medical imaging and how this technology has enabled us to look into the body at many different size scales, how imaging has enabled us to diagnose disease, and how imaging has made a difference in our healthcare...Federal dollars have been used to fund technology that’s going to change and improve health care. They already have. In the area of optics and high-resolution optical imaging, there’s going to be better healthcare, economic development with new companies, new jobs, and new areas of research to investigate...We can now do real-time microscopic imaging in the operating room without waiting for pathology.
      In Boppart Presents at Congressional Briefing
    5. In the end, I expect the cost of this system will be slightly more than what it replaces, but with significantly more capabilities, I do expect the cost of this system to continue to fall as more systems are developed and demand increases...This will be a boon for poorer hospitals and Third World or developing countries...It is essentially a portable imaging system with digital data that can be sent via cell-phone networks for analysis by experts in larger cities/hospitals.
      In Scientists awarded grant to continue developing optical device for medical exams
    6. The result of this – if successful, could really reduce our health care costs and streamline our delivery of health care.
      In NIH Awards Stephen Boppart $5M For A Bioengineering Research Partnership to Develop Handheld Optical Imaging Technology
    7. We are trying to build a small, handheld unit that has multiple tips...What’s collected is 3D digital data that can image several millimeters into tissue and at micron-scale resolution...The primary care physician is the best person to screen the general population for disease...“We think that it’s going to completely change the way we treat ear infections.
      In NIH Awards Stephen Boppart $5M For A Bioengineering Research Partnership to Develop Handheld Optical Imaging Technology
    8. The diagnosis is made based on very subjective interpretation – how the cells are laid out, the structure, the morphology...This is what we call the gold standard for diagnosis. We want to make the process of medical diagnostics more quantitative and more rapid.
      In New imaging technique accurately finds cancer cells, fast
    9. The analogy is like pushing someone on a swing. If you push at the right time point, the person on the swing will go higher and higher. If you don't push at the right point in the swing, the person stops...If we use the right optical frequencies to excite these vibrational states, we can enhance the resonance and the signal.
      In New imaging technique accurately finds cancer cells, fast
    10. Sometimes it's very hard to tell visually whether a cell is normal or abnormal...But molecularly, there are fairly clear signatures.
      In New imaging technique accurately finds cancer cells, fast
  1. Stephen A. Boppart

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    1-15 of 113 // 1 2 3 4 5 6 7 8 »
    1. Mentioned In 113 Articles

    2. Positive Results: A New Era for Medical Diagnostics - News from UIUC

      Explore beckman.illinois.edu (May 1 2012)

      Positive Results: A New Era for Medical Diagnostics - News from UIUC ...ancerous or benign. One of the Beckman researchers working toward this new future in diagnostics is Stephen Boppart, Co-chair of the Integrative Imaging research theme. Boppart has already taken technology for non-invasive or minimally invasive breast cancer assessments and r... (Read Full Article)

      Mentions:   Stephen A. Boppart   University of Illinois at Urbana-Champaign   Gabriel Popescu

    3. Real-time three-dimensional optical coherence tomography image-guided core-needle biopsy system

      Explore opticsinfobase.org (Apr 30 2012)

      Real-time three-dimensional optical coherence tomography image-guided core-needle biopsy system ...psy system Wei-Cheng Kuo, Jongsik Kim, Nathan D. Shemonski, Eric J. Chaney, Darold R. Spillman, and Stephen A. Boppart Biomedical Optics Express, Vol. 3, Issue 6, pp. 1149-1161 (2012) » View Full Text: Acrobat PDF (548... (Read Full Article)

      Mentions:   Stephen A. Boppart   University of Illinois at Urbana-Champaign   Wen-Chuan Kuo

    4. Computational adaptive optics for broadband optical interferometric tomography of biological tissue

      Explore pnas.org (Apr 26 2012)

      Computational adaptive optics for broadband optical interferometric tomography of biological tissue Aberrations in optical microscopy reduce image resolution and contrast, and can limit imaging depth when focusing into biological samples. Static correction of aberrations may be achieved through appropriate lens design, but this approach does not offer the flexibility of simultaneously correcting aberrations for all imaging depths, nor the adaptability to correct for sample-specific aberrations for high-quality tomographic optical imaging. Incorporation of adaptive optics (AO) methods have demonstrated considerable improvement in ... (Read Full Article)

      Mentions:   Stephen A. Boppart   University of Illinois at Urbana-Champaign   Steven G. Adie

    5. Computing the best high-resolution 3-D tissue images - News from Beckman Institute at UIUC

      Explore News Bureau (Apr 23 2012)

      Computing the best high-resolution 3-D tissue images - News from Beckman Institute at UIUC ...ven Adie, professor P. Scott Carney, graduate students Adeel Ahmad and Benedikt Graf, and professor Stephen Boppart. « Click photo to enlarge CHAMPAIGN, Ill. — Real-time, 3-D microscopic tissue imaging could be a re...... the Illinois team uses computer software to find and correct aberrations after the image is taken. Boppart's group teamed up with with Scott Carney, a professor of electrical and computer engineering and th... (Read Full Article)

      Mentions:   Stephen A. Boppart   University of Illinois at Urbana-Champaign   Steven G. Adie

    6. Aberration characterization for the optimal design of high-resolution endoscopic optical coherence tomography catheters

      Explore opticsinfobase.org (Mar 12 2012)

      Aberration characterization for the optimal design of high-resolution endoscopic optical coherence tomography catheters ...lution endoscopic optical coherence tomography catheters Wladimir A. Benalcazar, Woonggyu Jung, and Stephen A. Boppart Optics Letters, Vol. 37, Issue 6, pp. 1100-1102 (2012) » View Full Text: Acrobat PDF (290 KB) * OCI... (Read Full Article)

      Mentions:   Stephen A. Boppart   University of Illinois at Urbana-Champaign

    7. Integrated multimodal optical microscopy for structural and functional imaging of engineered and natural skin

      Explore Wiley Online Library (Feb 27 2012)

      Integrated multimodal optical microscopy for structural and functional imaging of engineered and natural skin ...1, 4. Ziad Mahmassani^3, 5. Eleni Antoniadou^4, 6. Ross DeVolder^5, 7. Hyunjoon Kong^5, 8. Marni D. Boppart^3, 9. Stephen A. (Read Full Article)

      Mentions:   Stephen A. Boppart   University of Illinois at Urbana-Champaign   Eric J. Chaney

    8. Device and method for imaging the ear using optical coherence tomography

      Explore uspto.gov (Feb 14 2012)

      Device and method for imaging the ear using optical coherence tomography A method of forming an image of tissue. The method includes non-invasively inserting a fiber-based device into a patient's ear canal and acquiring OCT data from ear tissue while the fiber-based device is in the ear canal. The method also includes converting the OCT data into at least one image. (Read Full Article)

      Mentions:   Stephen A. Boppart   University of Illinois at Urbana-Champaign

    9. 4th Biophotonics Summer School at University of Illinois at Urbana-Champaign May 21st - June 1st, 2012

      Explore Optical Coherence Tomography News (Feb 13 2012)

      4th Biophotonics Summer School at University of Illinois at Urbana-Champaign May 21st - June 1st, 2012 The 4th Biophotonics Summer School, funded in part by the Network for Computational Nanotechnology (a resource supported by the National Science Foundation), and the University of Illinois Imaging Initiative, will take place at the University of Illinois at Urbana-Champaign, May 21- June 1, 2012. This is a two-week event aimed at training graduate students and post-doctoral associates with research interests at the interface between optics, biomedicine, and nanotechnology. The School ... (Read Full Article)

      Mentions:   Stephen A. Boppart   University of Illinois at Urbana-Champaign

    10. Real Time Optical Coherence Tomography (OCT) of Human Tissue

      Explore ClinicalTrials.gov (Jan 6 2012)

      Real Time Optical Coherence Tomography (OCT) of Human Tissue ... breast including inflammatory breast cancer, Phyllodes tumor, sarcoma, etc. Study Chair: Stephen A Boppart, MD, PhD University of Illinois and Diagnostic Photonics, Inc. Responsible Party: Diagnostic Photon... (Read Full Article)

      Mentions:   Stephen A. Boppart   University of Illinois at Urbana-Champaign   Diagnostic Photonics

    11. Multimodal in vivo skin imaging with integrated optical coherence and multiphoton microscopy

      Explore IEEE Xplore (Dec 9 2011)

      Multimodal in vivo skin imaging with integrated optical coherence and multiphoton microscopy ... as skin cancer as well as potential pharmaceutical and cosmetic research applications. Graf, B.;   Boppart, S.; B. W. Graf is with the Department of Electrical and Computer Engineering, University of Illino... (Read Full Article)

      Mentions:   Stephen A. Boppart   University of Illinois at Urbana-Champaign

    12. Optical coherence tomography for rapid tissue screening and directed histological sectioning

      Explore IOS Press (Dec 3 2011)

      Optical coherence tomography for rapid tissue screening and directed histological sectioning In pathology, histological examination of the tissue is the “gold standard” to diagnose various diseases. It has contributed significantly toward identifying the abnormalities in tissues and cells, but has inherent drawbacks when used for fast and accurate diagnosis. These limitations include the lack of in vivo observation in real time and sampling errors due to limited number and area coverage of tissue sections. Its diagnostic yield also varies depending on ... (Read Full Article)

      Mentions:   Stephen A. Boppart   University of Illinois at Urbana-Champaign

    13. Boppart Presents at Congressional Briefing

      Explore interact.stltoday.com (Nov 15 2011)

      Boppart Presents at Congressional Briefing University of Illinois at Urbana-Champaign Professor Stephen Boppart will take part in a congressional briefing convened by the Optical Society of America (OSA). The br......vember 17 briefing will have the topic of “Medical Imaging: Research and Development Saving Lives.” Boppart, a professor of electrical and computer engineering and of bioengineering, will be the first of thr... (Read Full Article)

      Mentions:   Joseph M. Schmitt   Duke University   Stephen A. Boppart

    14. OSA to Host Congressional Briefing on Optics in Medical Imaging

      Explore Optical Coherence Tomography News (Nov 15 2011)

      OSA to Host Congressional Briefing on Optics in Medical Imaging ...Office Building (Gold Room), Washington, DC 20515 When:  Thursday, Nov. 17, 12-1:30 p.m. Who:     Stephen A. Boppart, M.D., Ph.D.   Bliss Professor of Engineering, Beckman Institute for Advanced Science and Tech... (Read Full Article)

      Mentions:   Joseph A. Izatt   Joseph M. Schmitt   Duke University

    15. Large BiOS program feeds SPIE Photonics West growth trend

      Explore Home: SPIE.org (Nov 1 2011)

      Large BiOS program feeds SPIE Photonics West growth trend ...rence imaging" * Xingde Li (Johns Hopkins Univ.), "Scanning fiber optic nonlinear endomicroscopy" * Stephen Boppart (Univ. of Illinois/Urbana Champaign), "Coherence imaging of cancer with novel optical sources" * Va... (Read Full Article)

      Mentions:   Massachusetts Institute of Technology   James G. Fujimoto   Massachusetts General Hospital

    16. Evaluation of caries-affected dentin with optical coherence tomography

      Explore scielo.br (Oct 26 2011)

      Evaluation of caries-affected dentin with optical coherence tomography ...ion. Lasers Surg Med. 2010 Jan;42:62-8.         [ Links ] 9. Fujimoto JG, Brezinski ME, Tearney GJ, Boppart SA, Bouma B, Hee MR, et al. Optical biopsy and imaging using optical coherence tomography. Nat Med. 19... (Read Full Article)

      Mentions:   Thorlabs   Michael R. Hee   Stephen A. Boppart

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