1. Stanford University

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    1. Mentioned In 271 Articles

    2. Endomicroscopy of the human cochlea using a micro-optical coherence tomography catheter

      Endomicroscopy of the human cochlea using a micro-optical coherence tomography catheter
      Sensorineural hearing loss (SNHL) is one of the most profound public health concerns of the modern era, affecting 466 million people today, and projected to affect 900 million by the year 2050. Advances in both diagnostics and therapeutics for SNHL have been impeded by the human cochlea's inaccessibility for in vivo imaging, resulting from its extremely small size, convoluted coiled configuration, fragility, and deep encasement in dense bone. Here ...
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    3. Head-to-head comparison of quantitative measurements between intravascular imaging systems: An in vitro phantom study

      Head-to-head comparison of quantitative measurements between intravascular imaging systems: An in vitro phantom study
      Introduction The present study aimed to compare the accuracy of quantitative measurements by contemporary intravascular imaging systems including optical frequency domain imaging (OFDI), frequency domain optical coherence tomography (FD-OCT), and 6 intravascular ultrasound (IVUS) systems. Methods We imaged five cylindrical phantom models made from an acrylic resin with known lumen diameters (1.51, 2.03, 3.04, 4.04, and 5.04 mm, respectively) using OFDI (FastView and LUNAWAVE, Terumo ...
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    4. Structural changes of corneal epithelium in belantamab-associated superficial keratopathy using anterior segment optical coherence tomography

      Structural changes of corneal epithelium in belantamab-associated superficial keratopathy using anterior segment optical coherence tomography
      Purpose To describe structural changes in corneal epithelium using anterior segment optical coherence tomography (AS-OCT) in two relapsed and refractory multiple myeloma (RRMM) patients with bilateral belantamab-associated superficial keratopathy (BASK). Observations: case 1 A 56-year-old male who was diagnosed with RRMM and initiated on belantamab mafodotin, presented on day 42 (three weeks after the second infusion) with decreased pinhole visual acuity from 20/20 and 20/25 to 20/70 ...
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    5. Integrating adaptive optics-SLO and OCT for multimodal visualization of the human retinal pigment epithelial mosaic

      Integrating adaptive optics-SLO and OCT for multimodal visualization of the human retinal pigment epithelial mosaic
      In vivo imaging of human retinal pigment epithelial (RPE) cells has been demonstrated through multiple adaptive optics (AO)-based modalities. However, whether consistent and complete information regarding the cellular structure of the RPE mosaic is obtained across these modalities remains uncertain due to limited comparisons performed in the same eye. Here, an imaging platform combining multimodal AO-scanning light ophthalmoscopy (AO-SLO) with AO-optical coherence tomography (AO-OCT) is developed to make a ...
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    6. Updates on ophthalmic imaging features of optic disc drusen, papilledema, and optic disc edema

      Updates on ophthalmic imaging features of optic disc drusen, papilledema, and optic disc edema
      Purpose of review Optic nerve head elevation can be associated with vision loss. This review provides an update regarding key features of optic disc drusen (ODD) compared with papilledema from increased intracranial pressure and optic disc edema from other causes. Recent findings Clinical history and funduscopic examination are not sufficient to correctly diagnose different causes of optic nerve head elevation. Multimodal ophthalmic imaging is noninvasive and should be used as ...
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    7. Spectrally sparse optical coherence tomography

      Spectrally sparse optical coherence tomography
      Abstract Swept-source optical coherence tomography (OCT) typically relies on expensive and complex swept-source lasers, the cost of which currently limits the suitability of OCT for new applications. In this work, we demonstrate spectrally sparse OCT utilizing randomly spaced low-bandwidth optical chirps, suitable for low-cost implementation with telecommunications grade devices. Micron scale distance estimation accuracy with a resolution of 40 m at a standoff imaging distance greater than 10 cm is ...
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    8. Current status of hybrid intravascular ultrasound and optical coherence tomography catheter for coronary imaging and percutaneous coronary intervention

      Current status of hybrid intravascular ultrasound and optical coherence tomography catheter for coronary imaging and percutaneous coronary intervention
      Both intravascular ultrasound (IVUS) and optical coherence tomography (OCT) play a crucial role in elucidating the pathophysiology of coronary artery disease (CAD) with the goal to improve patient outcomes of medical and/or interventional CAD management. However, no single intravascular imaging technique has been proven to provide complete and detailed evaluation of all CAD lesions due to some limitations. Although sequential use of multiple modalities may sometimes be performed, there ...
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    9. The optoretinogram reveals the primary steps of phototransduction in the living human eye

      The optoretinogram reveals the primary steps of phototransduction in the living human eye
      Photoreceptors initiate vision by converting photons to electrical activity. The onset of the phototransduction cascade is marked by the isomerization of photopigments upon light capture. We revealed that the onset of phototransduction is accompanied by a rapid (5 ms), nanometer-scale electromechanical deformation in individual human cone photoreceptors. Characterizing this biophysical phenomenon associated with phototransduction in vivo was enabled by high-speed phase-resolved optical coherence tomography in a line-field configuration that allowed ...
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    10. Progression of Photoreceptor Degeneration in Geographic Atrophy Secondary to Age-related Macular Degeneration

      Progression of Photoreceptor Degeneration in Geographic Atrophy Secondary to Age-related Macular Degeneration
      Importance Sensitive outcome measures for disease progression are needed for treatment trials in geographic atrophy (GA) secondary to age-related macular degeneration (AMD). Objective To quantify photoreceptor degeneration outside regions of GA in eyes with nonexudative AMD, to evaluate its association with future GA progression, and to characterize its spatio-temporal progression. Design, Setting, and Participants Monocenter cohort study (Directional Spread in Geographic Atrophy [ NCT02051998 ]) and analysis of data from a normative ...
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    11. Optical coherence tomography: A useful tool for identifying subclinical optic neuropathy in diagnosing multiple sclerosis

      Optical coherence tomography: A useful tool for identifying subclinical optic neuropathy in diagnosing multiple sclerosis
      Care of patients with multiple sclerosis (MS) has evolved in the last decade to shorten the time to confirm the diagnosis of clinically definite MS and to start disease-modifying drugs as soon as possible to decrease permanent disability and the risk of progressive disease. Such trends have been achieved by improving our understanding of the role of paraclinical tests such as the presence of oligoclonal bands on CSF examination, visual ...
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    12. 1-15 of 271 1 2 3 4 ... 16 17 18 »
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  2. About Stanford University

    Stanford University

    Stanford University was founded in 1891 by Leland and Jane Stanford to "promote the public welfare by exercising an influence on behalf of humanity and civilization." More than a century later, Stanford remains dedicated to finding solutions to the great challenges of the day and to preparing our students for leadership in today's complex world.