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    1. Mentioned In 263 Articles

    2. The optoretinogram reveals the primary steps of phototransduction in the living human eye

      Explore Science Advances Ophthalmology
      The optoretinogram reveals the primary steps of phototransduction in the living human eye
      Photoreceptors initiate vision by converting photons to electrical activity. The onset of the phototransduction cascade is marked by the isomerization of photopigments upon light capture. We revealed that the onset of phototransduction is accompanied by a rapid (5 ms), nanometer-scale electromechanical deformation in individual human cone photoreceptors. Characterizing this biophysical phenomenon associated with phototransduction in vivo was enabled by high-speed phase-resolved optical coherence tomography in a line-field configuration that allowed ...
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      Mentions: B. Hyle Park Stanford University University of Washington

    4. Progression of Photoreceptor Degeneration in Geographic Atrophy Secondary to Age-related Macular Degeneration

      Explore The JAMA Network Ophthalmology
      Progression of Photoreceptor Degeneration in Geographic Atrophy Secondary to Age-related Macular Degeneration
      Importance Sensitive outcome measures for disease progression are needed for treatment trials in geographic atrophy (GA) secondary to age-related macular degeneration (AMD). Objective To quantify photoreceptor degeneration outside regions of GA in eyes with nonexudative AMD, to evaluate its association with future GA progression, and to characterize its spatio-temporal progression. Design, Setting, and Participants Monocenter cohort study (Directional Spread in Geographic Atrophy [ NCT02051998 ]) and analysis of data from a normative ...
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      Mentions: Stanford University Carl Zeiss Meditec University of Utah

    6. Optical coherence tomography: A useful tool for identifying subclinical optic neuropathy in diagnosing multiple sclerosis

      Explore Neurology Neurology , Ophthalmology
      Optical coherence tomography: A useful tool for identifying subclinical optic neuropathy in diagnosing multiple sclerosis
      Care of patients with multiple sclerosis (MS) has evolved in the last decade to shorten the time to confirm the diagnosis of clinically definite MS and to start disease-modifying drugs as soon as possible to decrease permanent disability and the risk of progressive disease. Such trends have been achieved by improving our understanding of the role of paraclinical tests such as the presence of oligoclonal bands on CSF examination, visual ...
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      Mentions: Stanford University NYU Langone Medical Center

    10. Optical coherence tomography use in idiopathic intracranial hypertension

      Explore Home Neurology , Ophthalmology
      Optical coherence tomography use in idiopathic intracranial hypertension
      Idiopathic intracranial hypertension (IIH) is a condition in which elevated pressure in the cerebrospinal fluid can lead to optic nerve head (ONH) dysfunction and subsequent visual impairment. Physicians are currently limited in their ability to monitor and manage this condition, as clinical symptoms and exam findings are often delayed in response to changes in intracranial pressure. In order to find other biomarkers of disease, researchers are using imaging modalities such ...
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      Mentions: Stanford University

    11. TOPOGRAPHIC OPTICAL COHERENCE TOMOGRAPHY SEGMENTATION SHOWS LIMITED ELLIPSOID ZONE RECOVERY IN MILD HYDROXYCHLOROQUINE RETINOPATHY

      Explore LWW Online Ophthalmology
      TOPOGRAPHIC OPTICAL COHERENCE TOMOGRAPHY SEGMENTATION SHOWS LIMITED ELLIPSOID ZONE RECOVERY IN MILD HYDROXYCHLOROQUINE RETINOPATHY
      urpose: Optical coherence tomography (OCT) cross-sections have shown limited ellipsoid zone (EZ) improvement in mild hydroxychloroquine (HCQ) retinopathy within a few years after drug cessation. However, the extent, functional significance, and stability of such changes over time remain unclear. Methods: We created en face EZ maps using automated pixel-by-pixel segmentation for four patients with early-moderate HCQ toxicity followed for 6-8 years after drug cessation. These maps were compared with OCT ...
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      Mentions: Stanford University Carl Zeiss Meditec Mary K. Durbin

    12. A 3D Deep Learning System for Detecting Referable Glaucoma Using Full OCT Macular Cube Scans

      Explore TVST Journal Ophthalmology
      A 3D Deep Learning System for Detecting Referable Glaucoma Using Full OCT Macular Cube Scans
      Purpose : The purpose of this study was to develop a 3D deep learning system from spectral domain optical coherence tomography (SD-OCT) macular cubes to differentiate between referable and nonreferable cases for glaucoma applied to real-world datasets to understand how this would affect the performance. Methods : There were 2805 Cirrus optical coherence tomography (OCT) macula volumes (Macula protocol 512 128) of 1095 eyes from 586 patients at a single site that ...
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      Mentions: Stanford University The Chinese University of Hong Kong Jonathan D. Oakley

    13. Optical Microscopy and Coherence Tomography of Cancer in Living Subjects

      Explore ScienceDirect
      Optical Microscopy and Coherence Tomography of Cancer in Living Subjects
      Intravital microscopy (IVM) and optical coherency tomography (OCT) are two powerful optical imaging tools that allow visualization of dynamic biological activities in living subjects with subcellular resolutions. Recent advances in labeling and label-free techniques empower IVM and OCT for a wide range of preclinical and clinical cancer imaging, providing profound insights into the complex physiological, cellular, and molecular behaviors of tumors. Preclinical IVM and OCT have elucidated many otherwise inscrutable ...
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      Mentions: Stanford University Michigan State University Adam de la Zerda

    14. Angular compounding for speckle reduction in optical coherence tomography using geometric image registration algorithm and digital focusing

      Explore Nature Publishing Group
      Angular compounding for speckle reduction in optical coherence tomography using geometric image registration algorithm and digital focusing
      Optical coherence tomography (OCT) suffers from speckle noise due to the high spatial coherence of the utilized light source, leading to significant reductions in image quality and diagnostic capabilities. In the past, angular compounding techniques have been applied to suppress speckle noise. However, existing image registration methods usually guarantee pure angular compounding only within a relatively small field of view in the focal region, but produce spatial averaging in the ...
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      Mentions: Stanford University Adam de la Zerda

    15. Randomized Comparison Between Everolimus-Eluting Bioresorbable Scaffold and Metallic Stent Multimodality Imaging Through 3 Years

      Explore interventions.onlinejacc.org Cardiology
      Randomized Comparison Between Everolimus-Eluting Bioresorbable Scaffold and Metallic Stent Multimodality Imaging Through 3 Years
      Objectives The aim of this study was to investigate the vascular responses and fates of the scaffold after bioresorbable vascular scaffold (BVS) implantation using multimodality imaging. Background Serial comprehensive image assessments after BVS implantation in the context of a randomized trial have not yet been reported. Methods In the ABSORB Japan trial, 400 patients were randomized to a BVS (n = 266) or a cobalt-chromium everolimus-eluting stent (n = 134). Through 3 ...
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      Mentions: Beth Israel Deaconess Medical Center Columbia University Stanford University

    16. Topographic correlation between multifocal electroretinography, microperimetry, and spectral-domain optical coherence tomography of the macula in patients with birdshot chorioretinopathy

      Explore Home - Springer Ophthalmology
      Topographic correlation between multifocal electroretinography, microperimetry, and spectral-domain optical coherence tomography of the macula in patients with birdshot chorioretinopathy
      Purpose To correlate the findings of retinal function with multifocal electroretinogram (mfERG), microperimetry (MP), and structural assessments with spectral-domain optical coherence tomography (SD-OCT) in topographically corresponding areas of the macula of patients with birdshot chorioretinopathy (BSCR). Methods Patients diagnosed with BSCR by clinical and imaging findings were included in the study. The mfERG was performed using 61 hexagon stimulus patterns grouped into 5 rings (Diagnosys Inc., USA). Individual responses [N1-P1 ...
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      Mentions: Stanford University
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  4. About Stanford University

    Stanford University

    Stanford University was founded in 1891 by Leland and Jane Stanford to "promote the public welfare by exercising an influence on behalf of humanity and civilization." More than a century later, Stanford remains dedicated to finding solutions to the great challenges of the day and to preparing our students for leadership in today's complex world.

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