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    1. Mentioned In 256 Articles

    2. Optical coherence tomography use in idiopathic intracranial hypertension

      Optical coherence tomography use in idiopathic intracranial hypertension
      Idiopathic intracranial hypertension (IIH) is a condition in which elevated pressure in the cerebrospinal fluid can lead to optic nerve head (ONH) dysfunction and subsequent visual impairment. Physicians are currently limited in their ability to monitor and manage this condition, as clinical symptoms and exam findings are often delayed in response to changes in intracranial pressure. In order to find other biomarkers of disease, researchers are using imaging modalities such ...
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    3. TOPOGRAPHIC OPTICAL COHERENCE TOMOGRAPHY SEGMENTATION SHOWS LIMITED ELLIPSOID ZONE RECOVERY IN MILD HYDROXYCHLOROQUINE RETINOPATHY

      TOPOGRAPHIC OPTICAL COHERENCE TOMOGRAPHY SEGMENTATION SHOWS LIMITED ELLIPSOID ZONE RECOVERY IN MILD HYDROXYCHLOROQUINE RETINOPATHY
      urpose: Optical coherence tomography (OCT) cross-sections have shown limited ellipsoid zone (EZ) improvement in mild hydroxychloroquine (HCQ) retinopathy within a few years after drug cessation. However, the extent, functional significance, and stability of such changes over time remain unclear. Methods: We created en face EZ maps using automated pixel-by-pixel segmentation for four patients with early-moderate HCQ toxicity followed for 6-8 years after drug cessation. These maps were compared with OCT ...
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    4. A 3D Deep Learning System for Detecting Referable Glaucoma Using Full OCT Macular Cube Scans

      A 3D Deep Learning System for Detecting Referable Glaucoma Using Full OCT Macular Cube Scans
      Purpose : The purpose of this study was to develop a 3D deep learning system from spectral domain optical coherence tomography (SD-OCT) macular cubes to differentiate between referable and nonreferable cases for glaucoma applied to real-world datasets to understand how this would affect the performance. Methods : There were 2805 Cirrus optical coherence tomography (OCT) macula volumes (Macula protocol 512 128) of 1095 eyes from 586 patients at a single site that ...
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    5. Optical Microscopy and Coherence Tomography of Cancer in Living Subjects

      Optical Microscopy and Coherence Tomography of Cancer in Living Subjects
      Intravital microscopy (IVM) and optical coherency tomography (OCT) are two powerful optical imaging tools that allow visualization of dynamic biological activities in living subjects with subcellular resolutions. Recent advances in labeling and label-free techniques empower IVM and OCT for a wide range of preclinical and clinical cancer imaging, providing profound insights into the complex physiological, cellular, and molecular behaviors of tumors. Preclinical IVM and OCT have elucidated many otherwise inscrutable ...
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    6. Angular compounding for speckle reduction in optical coherence tomography using geometric image registration algorithm and digital focusing

      Angular compounding for speckle reduction in optical coherence tomography using geometric image registration algorithm and digital focusing
      Optical coherence tomography (OCT) suffers from speckle noise due to the high spatial coherence of the utilized light source, leading to significant reductions in image quality and diagnostic capabilities. In the past, angular compounding techniques have been applied to suppress speckle noise. However, existing image registration methods usually guarantee pure angular compounding only within a relatively small field of view in the focal region, but produce spatial averaging in the ...
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    7. Randomized Comparison Between Everolimus-Eluting Bioresorbable Scaffold and Metallic Stent Multimodality Imaging Through 3 Years

      Randomized Comparison Between Everolimus-Eluting Bioresorbable Scaffold and Metallic Stent Multimodality Imaging Through 3 Years
      Objectives The aim of this study was to investigate the vascular responses and fates of the scaffold after bioresorbable vascular scaffold (BVS) implantation using multimodality imaging. Background Serial comprehensive image assessments after BVS implantation in the context of a randomized trial have not yet been reported. Methods In the ABSORB Japan trial, 400 patients were randomized to a BVS (n = 266) or a cobalt-chromium everolimus-eluting stent (n = 134). Through 3 ...
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    8. Topographic correlation between multifocal electroretinography, microperimetry, and spectral-domain optical coherence tomography of the macula in patients with birdshot chorioretinopathy

      Topographic correlation between multifocal electroretinography, microperimetry, and spectral-domain optical coherence tomography of the macula in patients with birdshot chorioretinopathy
      Purpose To correlate the findings of retinal function with multifocal electroretinogram (mfERG), microperimetry (MP), and structural assessments with spectral-domain optical coherence tomography (SD-OCT) in topographically corresponding areas of the macula of patients with birdshot chorioretinopathy (BSCR). Methods Patients diagnosed with BSCR by clinical and imaging findings were included in the study. The mfERG was performed using 61 hexagon stimulus patterns grouped into 5 rings (Diagnosys Inc., USA). Individual responses [N1-P1 ...
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    9. Special Section Guest Editorial: Advances in Retinal Imaging

      Special Section Guest Editorial: Advances in Retinal Imaging
      The guest editorial provides an introduction to the Special Section on Advanced Retinal Imaging: Instrumentation, Methods, and Applications. The retina is a peripheral part of the central nerve system (CNS) and shares many similarities with the cerebral cortex. They both have layered anatomy, the same types of functional elements and neurotransmitters, and similar vascular organization and blood-tissue barriers. With far fewer neuronal cell types and simpler anatomical structures, the retina ...
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    10. A Spectral De-mixing Model for Triplex In Vivo Imaging of Optical Coherence Tomography Contrast Agents

      A Spectral De-mixing Model for Triplex In Vivo Imaging of Optical Coherence Tomography Contrast Agents
      The ability to detect multiple contrast agents simultaneously would greatly enhance Optical Coherence Tomography (OCT) images, providing nuanced biological context to physiological structures. However, previous OCT contrast agent work has been limited to scenarios where only a single contrast agent could be robustly detected within each voxel. We present a novel spectroscopic technique for de-mixing the spectral signal from multiple OCT contrast agents within a single voxel. We validate our ...
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    11. Gold Nanobipyramids as Second Near Infrared Optical Coherence Tomography Contrast Agents for In Vivo Multiplexing Studies

      Gold Nanobipyramids as Second Near Infrared Optical Coherence Tomography Contrast Agents for In Vivo Multiplexing Studies
      Developing contrast-enhanced optical coherence tomography (OCT) techniques is important for specific imaging of tissue lesions, molecular imaging, cell-tracking, and highly sensitive microangiography and lymphangiography. Multiplexed OCT imaging in the second near infrared (NIR-II) window is highly desirable since it allows simultaneous imaging and tracking of multiple biological events in high resolution with deeper tissue penetration in vivo . Here we demonstrate that gold nanobipyramids can function as OCT multiplexing contrast agents ...
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    12. Geographic Atrophy Segmentation in SD-OCT Images Using Synthesized Fundus Autofluorescence Imaging

      Geographic Atrophy Segmentation in SD-OCT Images Using Synthesized Fundus Autofluorescence Imaging
      Background and Objective Accurate assessment of geographic atrophy (GA) is critical for diagnosis and therapy of non-exudative age-related macular degeneration (AMD). Herein, we propose a novel GA segmentation framework for spectral-domain optical coherence tomography (SD-OCT) images that employs synthesized fundus autofluorescence (FAF) images. Methods An en-face OCT image is created via the restricted sub-volume projection of three-dimensional OCT data. A GA region-aware conditional generative adversarial network is employed to generate ...
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    13. Optical biopsy of penile cancer with in vivo confocal laser endomicroscopy

      Optical biopsy of penile cancer with in vivo confocal laser endomicroscopy
      Introduction Surgical management of penile cancer depends on accurate margin assessment and staging. Advanced optical imaging technologies may improve penile biopsy and organ-sparing treatment. We evaluated the feasibility of confocal laser endomicroscopy for intraoperative assessment of benign and malignant penile tissue. Patients and methods With institutional review board approval, 11 patients were recruited, 9 with suspected penile cancer, and 2 healthy controls. Confocal laser endomicroscopy using a 2.6-mm fiber-optic ...
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    14. Detection of glaucomatous optic neuropathy with spectral-domain optical coherence tomography: a retrospective training and validation deep-learning analysis

      Detection of glaucomatous optic neuropathy with spectral-domain optical coherence tomography: a retrospective training and validation deep-learning analysis
      ...rk was used to build the 3D deep-learning system. Three independent datasets (two from Hong Kong and one from Stanford, CA, USA), including 546, 267, and 1231 SDOCT volumes, respectively, were used for external validatio...
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    15. EVALUATION OF SEGMENTAL RETINAL ARTERITIS WITH OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY

      EVALUATION OF SEGMENTAL RETINAL ARTERITIS WITH OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY
      Purpose: To describe the vascular anatomy and intraluminal flow characteristics of segmental retinal arteritis (SRA) using structural and angiographic optical coherence tomography (OCT). Methods: Retrospective case series of consecutive patients presenting with SRA. All patients were evaluated at presentation with fundus photography, spectral domain OCT, and OCT angiography. One patient was imaged with dense B-scan OCT angiography. Results: Three eyes of three male patients were evaluated. All examinations were consistent ...
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  2. About Stanford University

    Stanford University

    Stanford University was founded in 1891 by Leland and Jane Stanford to "promote the public welfare by exercising an influence on behalf of humanity and civilization." More than a century later, Stanford remains dedicated to finding solutions to the great challenges of the day and to preparing our students for leadership in today's complex world.