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    1. Mentioned In 666 Articles

    2. St. Jude Medical Recognized as Innovative Technology Supplier of the Year by Nation’s Largest Health Care Contracting Organization

      St. Jude Medical Recognized as Innovative Technology Supplier of the Year by Nation’s Largest Health Care Contracting Organization
      ...or three consecutive years. To learn more about Novation, please follow @NovationNews. About St. Jude Medical St. Jude Medical is a global medical device manufacturer dedicated to transforming the treatment of some of th...
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    3. Optical coherence tomography characteristics of in-stent restenosis are different between first and second generation drug eluting stents ☆

      Optical coherence tomography characteristics of in-stent restenosis are different between first and second generation drug eluting stents ☆

      Aims Characterization of neointimal tissue is essential to understand the pathophysiology of in-stent restenosis (ISR) after drug eluting stent (DES) implantation. Using optical coherence tomography (OCT), we compared the morphologic characteristics of ISR between first and second generation DES. Methods and Results OCT was performed in 66 DES-ISR, defined as > 50% angiographic diameter stenosis within the stented segment. Patients with ISR of first generation sirolimus-eluting stents (SES), paclitaxel eluting stents (PES) and second generation zotarolimus-eluting stents (ZES), everolimus-eluting stents (EES) and biolimus-eluting stents (BES) were enrolled. Quantitative and qualitative ISR tissue analysis was performed at 1-mm intervals along the entire ...

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    4. NinePoint Medical Completes $34 Million Series B Financing to Expand Commercialization of its Breakthrough NvisionVLE™ Imaging System

      NinePoint Medical Completes $34 Million Series B Financing to Expand Commercialization of its Breakthrough NvisionVLE™ Imaging System
      ...directors, Mr. Miller has previously held senior positions with Siemens, Carl Zeiss, Analogic Corporation and LightLab Imaging, and brings a wealth of international operating experience to NinePoint’s board of directors....
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    5. Cardiac Allograft Vasculopathy Can Be Distinguished From Donor-Transmitted Coronary Atherosclerosis by Optical Coherence Tomography Imaging in a Heart Transplantation Recipient Double Layered Intimal Thickness

      Cardiac Allograft Vasculopathy Can Be Distinguished From Donor-Transmitted Coronary Atherosclerosis by Optical Coherence Tomography Imaging in a Heart Transplantation Recipient Double Layered Intimal Thickness

      Although survival after heart transplantation (HTx) has improved in recent years, cardiac allograft vasculopathy (CAV) is still the leading cause of remote morbidity and mortality in HTx recipients, partly because of difficulty with its diagnosis. In general, routine surveillance for CAV is advocated with coronary angiography accompanied by intravascular ultrasound (IVUS) if necessary. However, these modalities have limitations with respect to low spatial resolution, and sufficient qualitative/quantitative assessment of coronary intima has not been accomplished. Recently, optical coherence tomography (OCT) has emerged as a novel intracoronary imaging technique using an optical analogue of ultrasound with a spatial resolution of ...

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    6. Strategy for optimal side-branch positioning of bioresorbable vascular scaffolds in dedicated 2-stent techniques: Insights from optical coherence tomography

      Strategy for optimal side-branch positioning of bioresorbable vascular scaffolds in dedicated 2-stent techniques: Insights from optical coherence tomography

      We present a case of a left anterior descending artery/diagonal branch bifurcation successfully treated with a dedicated 2-stent technique utilizing bioresorbable vascular scaffolds, where the bifurcation angle did not strictly allow a T-stenting approach. We also propose a strategy to avoid or reduce scaffold overlap in the main branch, especially important in view of the bulkier size of these novel devices.

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    7. Variation in cross-correlation as a discriminator for microvessel imaging using clinical intravascular optical coherence tomography systems

      Variation in cross-correlation as a discriminator for microvessel imaging using clinical intravascular optical coherence tomography systems

      Cross-correlation of Intravascular Optical Coherence Tomography (IV-OCT) images is affected by image distortion due to the non-uniform rotational velocity of the imaging catheter. It results in non-representative cross-correlation maps such that for a static scan, the coefficients fluctuate from high to low correlation values. The variation in cross-correlation at flow locations is muted, in comparison to stationary regions. In the present study, the variation of correlation values and its standard deviation (SD) is used to suppress the distortion related noise effects and to extract flow maps from static scan images. The standard deviation of the cross-correlation variation can distinguish flow ...

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    8. Comparison of frequency domain optical coherence tomography and quantitative coronary angiography for the assessment of coronary lesions

      Comparison of frequency domain optical coherence tomography and quantitative coronary angiography for the assessment of coronary lesions

      Quantitative coronary angiography (QCA) has been used as a standard technique for the evaluation of coronary artery disease for many years. Intracoronary optical coherence tomography (OCT) offers higher resolution, faster image acquisition speeds and greater sensitivity than the intravascular ultrasound (IVUS). Recently developed frequency domain OCT (FD-OCT) systems overcome many technical limitations of conventional time domain OCT systems (TDOCT). The main objective of this study was to compare the FD-OCT and QCA measurements for the assessment of coronary lesions. A total of 21 stenoses in 18 patients were analysed using QCA and FD-OCT. The average minimum lumen diameter (MLD) and ...

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    9. Automated segmentation of porcine airway wall layers using optical coherence tomography: comparison with manual segmentation and histology

      Automated segmentation of porcine airway wall layers using optical coherence tomography: comparison with manual segmentation and histology

      The objective was to develop an automated optical coherence tomography (OCT) segmentation method. We evaluated three ex-vivo porcine airway specimens; six non-sequential OCT images were selected from each airway specimen. Histology was also performed for each airway and histology images were co-registered to OCT images for comparison. Manual segmentation of the airway luminal area, mucosa area, submucosa area and the outer airway wall area were performed for histology and OCT images. Automated segmentation of OCT images employed a despecking filter for pre-processing, a hessian-based filter for lumen and outer airway wall area segmentation, and K-means clustering for mucosa and submucosa ...

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    10. Sex differences in chronic obstructive pulmonary disease evaluated using optical coherence tomography

      Sex differences in chronic obstructive pulmonary disease evaluated using optical coherence tomography

      Although there are more women than men dying of chronic obstructive pulmonary disease (COPD) in the United States and elsewhere, we still do not have a clear understanding of the differences in the pathophysiology of airflow obstruction between the sexes. Optical coherence tomography (OCT) is an emerging imaging technology that has the capability of imaging small bronchioles with resolution approaching histology. Therefore, our objective was to compare OCT-derived airway wall measurements between males and females matched for lung size and in anatomically matched small airways. Subjects 50-80 yrs were enrolled in the British Columbia Lung Health Study and underwent OCT ...

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    11. Endoscopic Optical Coherence Tomography (OCT): Advances in Gastrointestinal Imaging

      Endoscopic Optical Coherence Tomography (OCT): Advances in Gastrointestinal Imaging

      In the rapidly evolving field of endoscopic gastrointestinal imaging, Optical Coherence Tomography (OCT) has found many diverse applications. We present the current status of OCT and its practical applications in imaging normal and abnormal mucosa in the esophagus, stomach, small and large intestines, and biliary and pancreatic ducts. We highlight technical aspects and principles of imaging, assess published data, and suggest future directions for OCT-guided evaluation and therapy.

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    12. Optical Coherence Tomography Control Systems And Methods

      Optical Coherence Tomography Control Systems And Methods

      In part, the invention relates to methods, devices, and systems suitable for controlling a light source (7). The light source is configured for use in a data collection system such as an optical coherence tomography system (5). The light source (7) can be controlled with a drive waveform (10, 22, 55, 70). Linearizing and symmetrizing parameters of the light source (7) such as forward (35, 60, 75) and backward (33, 63, 77) scan durations is achieved using a suitable drive waveform (22, 55, 70).

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    13. Optical coherence tomography imaging of intrastent neointimal bridge caused by semicircumferencial dissection after drug eluting balloon dilatation of instent restenosis of sapheneous venous graft

      Optical coherence tomography imaging of intrastent neointimal bridge caused by semicircumferencial dissection after drug eluting balloon dilatation of instent restenosis of sapheneous venous graft

      During redilatation of a stent by a balloon, the dissection of the neointimal tissue commonly can be detected by IVUS or OCT, but the exact clinical relevance of the dissection in variable type is not known in the case of angiographically good result. Sixty-two year old female patient had CABG operation in 1998 (LIMA-LAD, sequential SVG to the 2nd OM branch of the LCx and the PL of the RCA). Between 2006 and 2012 she had 5 PCIs with stent implantations and balloon redilations in the sequential SVG (altogether 5 BM stents and 1 DES were implanted). The last intervention ...

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      Mentions: St. Jude Medical
    14. Multivessel Honeycomb-Like Structure Finding in Optical Coherence Tomography

      Multivessel Honeycomb-Like Structure Finding in Optical Coherence Tomography

      A 66-year-old man with a history of chronic atrial fibrillation was referred to our hospital due to pre-operative cardiac evaluation for intestinal stenosis. An electrocardiogram showed negative T in leads II, III, aVF, and V 3 to V 5 , and an echocardiogram showed moderate hypokinesis in the anteroseptal left ventricular wall. Coronary angiography revealed multiple linear filling defects with haziness in the right coronary artery and left anterior descending artery (Figure 1 A and Figure 1 B). After surgery for intestinal stenosis, we performed a staged percutaneous coronary intervention for right coronary artery and left anterior descending artery stenosis. In ...

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      Mentions: St. Jude Medical
    15. Randomised comparison of strut coverage between Nobori biolimus-eluting and sirolimus-eluting stents: an optical coherence tomography analysis

      Randomised comparison of strut coverage between Nobori biolimus-eluting and sirolimus-eluting stents: an optical coherence tomography analysis

      Aims: The aims of this study were to compare strut tissue coverage at six-month follow-up after Nobori biolimus-eluting stent (N-BES) versus sirolimus-eluting stent (SES) implantation. Methods and results: A total of 120 patients with a single stenotic lesion requiring revascularisation were randomly assigned to either N-BES (n=60) or SES (n=60). Baseline optical coherence tomography (OCT) was performed post stent implantation, and follow-up OCT was scheduled at six months. Post-intervention and follow-up OCT analyses were available in 51 (85.0%) and 52 (86.7%) patients, respectively. The primary endpoint was the percentage of uncovered struts at follow-up OCT in ...

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    16. Effect of the Endothelial Shear Stress Patterns on Neointimal Proliferation Following Drug-Eluting Bioresorbable Vascular Scaffold Implantation : An Optical Coherence Tomography Study

      Effect of the Endothelial Shear Stress Patterns on Neointimal Proliferation Following Drug-Eluting Bioresorbable Vascular Scaffold Implantation : An Optical Coherence Tomography Study

      Objectives The goal of this study was to investigate the effect of endothelial shear stress (ESS) on neointimal formation following an Absorb bioresorbable vascular scaffold (BVS) (Abbott Vascular, Santa Clara, California) implantation. Background Cumulative evidence, derived from intravascular ultrasound–based studies, has demonstrated a strong association between local ESS patterns and neointimal formation in bare-metal stents, whereas in drug-eluting stents, there are contradictory data about the effect of ESS on the vessel wall healing process. The effect of ESS on neointimal development following a bioresorbable scaffold implantation remains unclear. Methods Twelve patients with an obstructive lesion in a relatively straight ...

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  2. About St. Jude Medical

    St. Jude Medical

    St. Jude Medical develops medical technology and services that focus on putting more control into the hands of those who treat cardiac, neurological and chronic pain patients worldwide.  St. Jude Medical is headquartered in St. Paul, Minnesota and has four major focus areas that include: cardiac rhythm management, atrial fibrillation, cardiovascular and neuromodulation.  St. Jude acquired Lightlab Imaging in 2010. Lightlab makes intravascular OCT imaging products.

  3. Quotes about St. Jude Medical

    1. We are pleased to add this new growth platform to our cardiovascular business, especially in conjunction with our FFR platform, and we are excited by the many opportunities this acquisition creates for St. Jude Medical and LightLab, physician customers and their patients...We welcome LightLab and its employees to St. Jude Medical.
      Daniel J. Starks in St. Jude Medical to Acquire LightLab Imaging for $90M in Cash
    2. We are excited to join with a partner who shares our vision of improving patient outcomes and reducing health care costs through solutions which enable physicians to make earlier and more accurate treatment decisions... We believe St. Jude Medical's U.S. and international footprint, along with its existing FFR measurement technology, will accelerate growth for our industry-leading OCT technology. We look forward to joining the St. Jude Medical team.
      David W. Kolstad in St. Jude Medical to Acquire LightLab Imaging for $90M in Cash
    3. St. Jude Medical's acquisition of LightLab confirms the validity and potential utility of this leading edge technology...We are planning a best-in-class OCT solution. We currently have CE Mark in Europe on our first generation platform, and we are targeting a release of our second generation platform in Europe early next year. We anticipate that this system will incorporate a smaller catheter, shorter prep time, faster pullback speed, and a longer imaging segment than the current device.
      Scott Huennekens in Volcano Announces Positive Clinical Experience With Its Second Generation OCT Catheter, Prepares for U.S. Regulatory Study