1. St. Jude Medical

    0 Comments Leave a Comment

    1-15 of 693 1 2 3 4 ... 45 46 47 »
    1. Mentioned In 693 Articles

    2. Visualization of Complete Regression of Pulmonary Arterial Remodeling on Optical Coherence Tomography in a Patient With Pulmonary Arterial Hypertension

      Visualization of Complete Regression of Pulmonary Arterial Remodeling on Optical Coherence Tomography in a Patient With Pulmonary Arterial Hypertension

      Optical coherence tomography (OCT) is an interferometer- based imaging modality with a high resolution and its usefulness has recently attracted much attention in cardiovascular medicine.1–3 We have recently shown that OCT is useful in the management of pulmonary hypertension, not only for diagnosis but also for evaluation of treatment.4 Here, we show that OCT is also useful to document regression of pulmonary arterial remodeling in response to medical treatment. A 35-year-old woman with an 18-year history of Sjögren syndrome treated with oral prednisolone had a 4-year history of shortness of breath on exertion. On her first ...

      Read Full Article
    3. Intravascular Optical Coherence Tomography System with Pressure Monitoring Interface and Accessories

      Intravascular Optical Coherence Tomography System with Pressure Monitoring Interface and Accessories

      An optical coherence tomography system and method with integrated pressure measurement. In one embodiment the system includes an interferometer including: a wavelength swept laser; a source arm in communication with the wavelength swept laser; a reference arm in communication with a reference reflector; a first photodetector having a signal output; a detector arm in communication with the first photodetector, a probe interface; a sample arm in communication with a first optical connector of the probe interface; an acquisition and display system comprising: an A/D converter having a signal input in communication with the first photodetector signal output and a ...

      Read Full Article
    4. Drug-eluting stent implantation in patients with acute coronary syndrome - the Activity of Platelets after Inhibition and Cardiovascular Events: Optical Coherence Tomography (APICE OCT) study

      Drug-eluting stent implantation in patients with acute coronary syndrome - the Activity of Platelets after Inhibition and Cardiovascular Events: Optical Coherence Tomography (APICE OCT) study

      Aims: To our knowledge, no randomised study has compared rates of uncovered stent struts in everolimus (EES) vs. new-generation zotarolimus-eluting (ZES-R) stents in acute coronary syndrome (ACS). The aim of our study was to evaluate the completeness of neointimal coverage with optical coherence tomography (OCT) in ACS patients treated with drug-eluting stents (DES) comparing EES versus new-generation ZES-R. Methods and results: All eligible ACS patients admitted to four Italian centres with a clinical indication for culprit lesion intervention were randomised 1:1 to EES or ZES-R. The primary study endpoint was the percentage of uncovered stent struts evaluated by optical ...

      Read Full Article
    5. Comparison by Optical Coherence Tomography of the Frequency of Lipid Coronary Plaques in Current Smokers, Former Smokers, and Non-smokers

      Comparison by Optical Coherence Tomography of the Frequency of Lipid Coronary Plaques in Current Smokers, Former Smokers, and Non-smokers

      Smoking is associated with high incidence of cardiovascular events including acute coronary syndrome (ACS). We sought to characterize coronary plaques in patients with ongoing smoking using optical coherence tomography (OCT) compared to former smokers and nonsmokers. We identified 465 coronary plaques from 182 subjects who underwent OCT imaging for all three coronary arteries. Subjects were divided into 3 groups: current smokers (n=41), former smokers (n=67) and nonsmokers (n=74). OCT analysis included the presence of lipid rich plaque, thin-cap fibroatheroma (TCFA), calcification, maximum lipid arc, lipid core length, lipid index, and fibrous cap thickness (FCT). Lipid index was ...

      Read Full Article
    6. Optical coherence tomographic observation of morphological features of neointimal tissue after drug-eluting stent implantation

      Optical coherence tomographic observation of morphological features of neointimal tissue after drug-eluting stent implantation

      Purpose The impacts of different time courses and the degree of neointimal growth on neointimal morphology have not yet been sufficiently investigated. Therefore, we evaluated the morphological features of neointimal tissue after drug-eluting stent (DES) implantation using optical coherence tomography (OCT). Materials and Methods The morphological features of neointimal tissue in stented segments with a maximal percentage of cross-sectional area (CSA) stenosis of neointima were evaluated in 507 DES-treated lesions with >100 µm mean neointimal thickness on follow-up OCT. Neointimal tissue was categorized as homogeneous, heterogeneous, layered, or neoatherosclerotic. Results In lesions with <50% of neointimal CSA stenosis, homogeneous neointima ...

      Read Full Article
    7. Coronary Aneurysm Closure With Pericardial Covered Stent Evaluated With Optical Coherence Tomography

      Coronary Aneurysm Closure With Pericardial Covered Stent Evaluated With Optical Coherence Tomography

      A 62-year-old man with personal history of arterial hypertension and smoking was admitted to our hospital with ST elevation myocardial infarction. Intravenous fibrinolytic therapy was given by emergency services during hospital transfer, which was effective. Routine coronary angiography showed moderate lesion on the proximal left anterior descending, proximal coronary aneurysm (Figure 1A, asterisk) and significant lesions at mid segment of circumflex (white arrow) and proximal segment of the second marginal (arrowhead). The case was discussed with the heart team and the decision was made to perform percutaneous coronary intervention. Balloon predilation was performed and drug-eluting stent was implanted in second ...

      Read Full Article
      Mentions: St. Jude Medical
    8. Intravascular Frequency-Domain Optical Coherence Tomography Assessment of Carotid Artery Disease in Symptomatic and Asymptomatic Patients

      Intravascular Frequency-Domain Optical Coherence Tomography Assessment of Carotid Artery Disease in Symptomatic and Asymptomatic Patients

      Objectives The goal of this study was to investigate carotid plaque characteristics in symptomatic versus asymptomatic patients with the use of nonocclusive optical coherence tomography (OCT). Background The identification of asymptomatic patients with carotid disease who are at risk of stroke remains a challenge. There is an increasing awareness that plaque characteristics may best risk-stratify this population. We hypothesized that OCT, a new high-resolution (∼10 μm) imaging modality, might be useful for the identification of low-risk versus high-risk carotid plaque features and help us to understand the relationship between carotid diameter stenosis and plaque morphology to ischemic stroke. Methods Fifty-three ...

      Read Full Article
    9. Validation of Airway Wall Measurements by Optical Coherence Tomography in Porcine Airways

      Validation of Airway Wall Measurements by Optical Coherence Tomography in Porcine Airways

      Examining and quantifying changes in airway morphology is critical for studying longitudinal pathogenesis and interventions in diseases such as chronic obstructive pulmonary disease and asthma. Here we present fiber-optic optical coherence tomography (OCT) as a nondestructive technique to precisely and accurately measure the 2-dimensional cross-sectional areas of airway wall substructure divided into the mucosa (WA muc ), submucosa (WA sub ), cartilage (WA cart ), and the airway total wall area (WAt). Porcine lung airway specimens were dissected from freshly resected lung lobes (N = 10). Three-dimensional OCT imaging using a fiber-optic rotary-pullback probe was performed immediately on airways greater than 0.9 mm ...

      Read Full Article
    10. Feasibility of Intracoronary Frequency Domain Optical Coherence Tomography Derived Fractional Flow Reserve for the Assessment of Coronary Artery Stenosis

      Feasibility of Intracoronary Frequency Domain Optical Coherence Tomography Derived Fractional Flow Reserve for the Assessment of Coronary Artery Stenosis

      Frequency domain optical coherence tomography (FD-OCT) provides cross-sectional images of coronary arteries and deployed stents with micron resolution and measures lumen dimensions with excellent reproducibility. FD-OCT combined with a blood flow resistances model can overcome many limitations of conventional measures of stenosis severity based on quantitative coronary angiography (QCA) and intravascular ultrasound (IVUS). The aim of this feasibility study was to investigate the relationship between pressure derived fractional flow reserve (FFR) and FD-OCT derived FFR, a new method for quantitative measure of stenosis severity that estimates the blood flow resistance and microvascular resistance of the vessel segments imaged by FD-OCT ...

      Read Full Article
    11. Two Different Mechanisms of Very Late Stent Thrombosis: Assessment and Guidance of Therapy with Optical Coherence Tomography

      Two Different Mechanisms of Very Late Stent  Thrombosis: Assessment and Guidance of Therapy  with Optical Coherence Tomography

      Incomplete coverage of stent struts and atherosclerosis within the neointima are the two most frequently mechanisms of very late stent thrombosis (VLST). As the determination by conventional coronary angiography is not always possible, the use of optical coherence tomography (OCT) is getting more and more important. The high resolution of OCT allows a closer look to the pathomechanisms of VLST, which helps to make the right decisions in the catheterization laboratory. These cases demonstrate the evaluation of VLST by OCT and the resulting therapeutical decisions.

      Read Full Article
    12. 1-15 of 693 1 2 3 4 ... 45 46 47 »
  1. Categories

    1. Applications:

      Art, Cardiology, Dentistry, Dermatology, Developmental Biology, Gastroenterology, Gynecology, Microscopy, NDE/NDT, Neurology, Oncology, Ophthalmology, Other Non-Medical, Otolaryngology, Pulmonology, Urology
    2. Business News:

      Acquisition, Clinical Trials, Funding, Other Business News, Partnership, Patents
    3. Technology:

      Broadband Sources, Probes, Tunable Sources, Velocimetry
    4. Miscellaneous:

      Jobs & Studentships, Student Theses, Textbooks
  2. About St. Jude Medical

    St. Jude Medical

    St. Jude Medical develops medical technology and services that focus on putting more control into the hands of those who treat cardiac, neurological and chronic pain patients worldwide.  St. Jude Medical is headquartered in St. Paul, Minnesota and has four major focus areas that include: cardiac rhythm management, atrial fibrillation, cardiovascular and neuromodulation.  St. Jude acquired Lightlab Imaging in 2010. Lightlab makes intravascular OCT imaging products.

  3. Quotes about St. Jude Medical

    1. We are pleased to add this new growth platform to our cardiovascular business, especially in conjunction with our FFR platform, and we are excited by the many opportunities this acquisition creates for St. Jude Medical and LightLab, physician customers and their patients...We welcome LightLab and its employees to St. Jude Medical.
      Daniel J. Starks in St. Jude Medical to Acquire LightLab Imaging for $90M in Cash
    2. We are excited to join with a partner who shares our vision of improving patient outcomes and reducing health care costs through solutions which enable physicians to make earlier and more accurate treatment decisions... We believe St. Jude Medical's U.S. and international footprint, along with its existing FFR measurement technology, will accelerate growth for our industry-leading OCT technology. We look forward to joining the St. Jude Medical team.
      David W. Kolstad in St. Jude Medical to Acquire LightLab Imaging for $90M in Cash
    3. St. Jude Medical's acquisition of LightLab confirms the validity and potential utility of this leading edge technology...We are planning a best-in-class OCT solution. We currently have CE Mark in Europe on our first generation platform, and we are targeting a release of our second generation platform in Europe early next year. We anticipate that this system will incorporate a smaller catheter, shorter prep time, faster pullback speed, and a longer imaging segment than the current device.
      Scott Huennekens in Volcano Announces Positive Clinical Experience With Its Second Generation OCT Catheter, Prepares for U.S. Regulatory Study