1. Srinivas R. Sadda

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    1. Mentioned In 182 Articles

    2. Relationship between angiographic and optical coherence tomographic (OCT) parameters for quantifying choroidal neovascular lesions

      Background To correlate the volume of various spaces on optical coherence tomography (OCT) with fluorescein angiographic (FA) parameters in neovascular age-related macular degeneration (AMD). Methods Sixty-five consecutive cases of active subfoveal choroidal neovascularization (CNV) associated with AMD were retrospectively collected. Area and greatest linear dimension of CNV lesion components were calculated on FA. Corresponding StratusOCT image sets were analyzed using custom software (termed OCTOR), which allows manual measurement of the ...
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    3. Macular Thickness Measurements in Normal Eyes With Time-Domain and Fourier-Domain Optical Coherence Tomography

      Purpose: To compare macular thickness measurements using time-domain optical coherence tomography (OCT) and Fourier-domain OCT. Methods: Thirty-two eyes from 32 normal patients underwent complete ophthalmic evaluation. Macular scanning using the StratusOCT and the RTVue-100 OCT were performed for a total of three times each on the same visit. The average retinal thicknesses of the nine macular sectors as defined by the Early Treatment Diabetic Retinopathy Study, along with the foveal ...
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    4. Comparison of Clinically Relevant Findings from High-Speed Fourier-Domain and Conventional Time-Domain Optical Coherence Tomography

      Purpose To compare the sensitivities of high-speed Fourier-domain optical coherence tomography (FD-OCT) and conventional time-domain (TD) OCT for the detection of clinical findings important in the management of common vitreoretinal disorders. Design Prospective, observational study. Methods FD-OCT scans (128 B scans 512 A scans) were obtained using a prototype instrument (3 D-OCT; Topcon, Tokyo, Japan) in 50 eyes of 28 consecutive patients undergoing conventional high-resolution (6 B scans 512 A ...
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    5. Signal Strength is an Important Determinant of Accuracy of Nerve Fiber Layer Thickness Measurement by Optical Coherence Tomography.

      Purpose: To investigate the effect of signal strength on the measurement of the retinal nerve fiber layer (RNFL) using optical coherence tomography (OCT). Methods: Eyes with known or suspected glaucoma or nonglaucomatous optic atrophy were scanned twice within the same visit using Stratus OCT's Fast Nerve Fiber Layer Thickness protocol. Only those eyes with 2 high-quality scans (signal strengths of at least 5 and different from each other, no ...
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    6. Association Of The Extent Of Diabetic Macular Edema As Assessed By Optical Coherence Tomography With Visual Acuity And Retinal Outcome Variables.

      Purpose: To determine whether the extensiveness of diabetic macular edema using a 10-step scale based on optical coherence tomography explains pretreatment variation in visual acuity and predicts change in macular thickness or visual acuity after laser photocoagulation. Methods: Three hundred twenty-three eyes from a randomized clinical trial of two methods of laser photocoagulation for diabetic macular edema were studied. Baseline number of thickened optical coherence tomography subfields was used to ...
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    7. Evaluation of Optical Coherence Tomography Central Retinal Thickness Parameters for use as Anatomic Outcomes in Clinical Trials for Neovascular Age-Related Macular Degeneration

      ...e ^1, Sandra Liakopoulos ^2, Renu V Jivrajka ^1, Karen T Chang ^3, Tarek Alasil ^1, Alexander C Walsh ^1, and SriniVas R. Sadda ^4^* ^^1 Department of Ophthalmology, Doheny Retina Institute, Los Angeles, California, Unit...
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    8. Quantitative Subanalysis of Intraretinal Cystoid Spaces and Outer Nuclear Layer using Optical Coherence Tomography in Neovascular Age-Related Macular Degeneration

      ...elated Macular Degeneration Amir H Kashani ^1, Pearse A Keane ^2, Laurie Dustin ^3, Alexander C Walsh ^2, and SriniVas R. Sadda ^4^* ^^1 Ophthalmology, Doheny Eye Institute, Los Angeles, California, United States ^2 Opht...
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      Purpose: To describe morphologic features of traumatic macular holes on optical coherence tomography and to correlate them with clinical findings. Methods: Seventy-three consecutive patients diagnosed with full-thickness traumatic macular holes involving the fovea underwent complete ophthalmic evaluation followed by horizontal and vertical li...
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    10. Quantitative Optical Coherence Tomography Findings in Various Subtypes of Neovascular Age-Related Macular Degeneration

      PURPOSE. To compare the volume of various spaces visible on optical coherence tomography (OCT) images in different angiographic lesion subtypes of neovascular age-related macular degeneration (AMD). METHODS. Sixty-six cases of previously untreated, active subfoveal choroidal neovascularization (CNV) associated with AMD were retrospectively collected. CNV lesions were classified as occult with no classic CNV, minimally classic CNV, predominantly classic CNV, or CNV lesions with associated retinal angiomatous proliferation (RAP). Corresponding OCT ...
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    11. Relationship Between Optical Coherence Tomography Retinal Parameters and Visual Acuity in Neovascular Age-Related Macular Degeneration

      Purpose To investigate the relationship between optical coherence tomography (OCT)-derived measurements of retinal morphology and visual acuity in patients with neovascular age-related macular degeneration (AMD). Design Retrospective cross-sectional study. Participants A total of 216 consecutive patients (216 eyes) newly diagnosed with neovascular AMD who underwent StratusOCT imaging at the time of diagnosis. Methods Best-corrected Snellen visual acuity was recorded for each patient. Raw exported StratusOCT images for each patient ...
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    12. Optical Coherence Tomography Measurements and Analysis Methods in Optical Coherence Tomography Studies of Diabetic Macular Edema

      Objective: To evaluate optical coherence tomography (OCT) measurements and methods of analysis of OCT data in studies of diabetic macular edema (DME). Design Associations of pairs of OCT variables and results of 3 analysis methods using data from 2 studies of DME. Participants Two hundred sixty-three subjects from a study of modified Early Treatment of Diabetic Retinopathy Study (mETDRS) versus modified macular grid (MMG) photocoagulation for DME and 96 subjects ...
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    13. Comparison of the Optical Coherence Tomographic Features of Choroidal Neovascular Membranes in Pathologic Myopia versus Age-Related Macular Degeneration, using Quantitative Subanalysis

      ... Sandra Liakopoulos ^2, Karen T Chang ^1, Florian M Heussen ^2, Sharel C Ongchin ^1, Alexander C Walsh ^1 and Srinivas R Sadda ^1^* ^1 Doheny Eye Institute, United States ^2 University of Cologne, Germany ^* To whom corr...
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    14. The effects of intravitreous bevacizumab on retinal neovascular membrane and normal capillaries in rabbits.

      Related Articles The effects of intravitreous bevacizumab on retinal neovascular membrane and normal capillaries in rabbits. Invest Ophthalmol Vis Sci. 2007 Dec;48(12):5708-15 Authors: Ameri H, Chader GJ, Kim JG, Sadda SR, Rao NA, Humayun MS PURPOSE: To evaluate the effects of intravitreous bevacizumab in a rabbit retinal neovascularization model. METHODS: Twenty-four rabbits were divided into five groups. Group A included four rabbits; all other groups included five ...
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    15. 166-182 of 182 « 1 2 ... 9 10 11 12
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  2. About Srinivas R. Sadda

    Srinivas R. Sadda

    Srinivas R. Sadda, MD, Assistant Professor of Ophthalmology, Doheny Image Reading Center, Doheny Eye Institute, UCLA.


    1. With CIRRUS FastTrac, I can place a highest resolution 20x B-Scan precisely on the area I am treating at each successive visit to see the fine details of the patient’s response to treatment...It’s also very helpful for removing any eye motion from the larger cube scans without disturbing my patient flow because it works so quickly. My initial experience is that FastTrac is about 30 percent faster than other tracking methods I have used.
      In Modernized new OCT platforms span full spectrum of multi-modality imaging for glaucoma and retinal disease