1. Srinivas R. Sadda

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    1. Mentioned In 182 Articles

    2. Relationship among visual field, blood flow, and neural structure measurements in glaucoma

      Relationship among visual field, blood flow, and neural structure measurements in glaucoma
      Purpose:To determine the relationship among visual field, neural structural, and blood flow measurements in glaucoma. Methods:Case-control study. Forty-seven eyes of 42 patients with perimetric glaucoma were age-matched with 27 normal eyes of 27 patients. All patients underwent Doppler Fourier-domain optical coherence tomography to measure retinal blood flow and standard glaucoma evaluation with visual field testing and quantitative structural imaging. Linear regression analysis was performed to analyze the relationship ...
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    3. Impact of scanning density on spectral domain optical coherence tomography assessments in neovascular age-related macular degeneration

      Impact of scanning density on spectral domain optical coherence tomography assessments in neovascular age-related macular degeneration
      Purpose:  To determine the effect of optical coherence tomography (OCT) B-scan density on the qualitative assessment of neovascular age-related macular degeneration (AMD). Methods:  Data were collected from 59 patients imaged with Topcon 3D OCT-1000 (128 B-scans × 512 A-scans). Custom software was used to generate less dense subsets of scans: 1/16 (eight B-scans), 1/8 (16 B-scans), 1/4 (32 B-scans) and 1/2 (64 B-scans). At each B-scan density ...
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    4. Correlation Between Optical Coherence Tomography-Derived Assessments of Lower Tear Meniscus Parameters and Clinical Features of Dry Eye Disease

      Correlation Between Optical Coherence Tomography-Derived Assessments of Lower Tear Meniscus Parameters and Clinical Features of Dry Eye Disease
      Purpose: To measure the correlation between subjective symptom score, conventional clinical tests, and Fourier-domain optical coherence tomography (FD-OCT) of lower tear meniscus parameters in patients with dry eye disease. Methods: Eighteen patients with dry eye disease requiring medical therapy and/or punctal occlusion were recruited for this prospective, nonrandomized, observational case series. Severity of symptoms of dry eye disease was assessed using the Indiana University Dry Eye Questionnaire 2002. Clinical ...
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    5. Diurnal Variation of Choroidal Thickness in Normal, Healthy Subjects Measured by Spectral Domain Optical Coherence Tomography

      Diurnal Variation of Choroidal Thickness in Normal, Healthy Subjects Measured by Spectral Domain Optical Coherence Tomography
      Purpose. To describe the pattern and magnitude of diurnal variation of choroidal thickness (CT), its relation to systemic and ocular factors, and to determine the intervisit reproducibility of diurnal patterns. Methods. A prospective study was conducted on 12 healthy volunteers who each underwent sequential ocular imaging on two separate days at five fixed, 2-hour time intervals. Spectral domain optical coherence tomography (OCT) with enhanced depth imaging and image tracking was ...
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    6. Assessment of Differential Pharmacodynamic Effects using Optical Coherence Tomography in Neovascular Age-Related Macular Degeneration

      Assessment of Differential Pharmacodynamic Effects using Optical Coherence Tomography in Neovascular Age-Related Macular Degeneration
      Purpose: To assess the differential pharmacodynamic effects of bevacizumab (Avastin), pegaptanib (Macugen), and verteporfin photodynamic therapy (PDT), using novel OCT parameters, in a recently completed phase III/IV clinical trial. Methods: Data from 122 patients participating in the Avastin (Bevacizumab) for Choroidal neovascularization (ABC) trial, were evaluated. Stratus OCT images were analyzed using custom software - changes in volume of the neurosensory retina, subretinal fluid (SRF), pigment epithelium detachment (PED), and ...
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    7. Simple Estimation of Clinically-Relevant Lesion Volumes using Spectral Domain-Optical Coherence Tomography in Neovascular Age-Related Macular Degeneration

      Simple Estimation of Clinically-Relevant Lesion Volumes using Spectral Domain-Optical Coherence Tomography in Neovascular Age-Related Macular Degeneration
      ...aphy in Neovascular Age-Related Macular Degeneration 1. Florian M. Heussen, MD^1, 2. Yanling Ouyang, MD^1, 3. SriniVas R. Sadda, MD^1 and 4. Alexander C. Walsh, MD^1 1. ^1Doheny Eye Institute and the Department of Ophtha...
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    8. Mapping and diagnosis of macular edema by optical coherence tomography

      Mapping and diagnosis of macular edema by optical coherence tomography
      The present invention discloses a method for comparing the detection of clinically significant diabetic macular edema by an optical coherence tomography (OCT) grid scanning protocol and biomicroscopic examination. Also provided are computer implemented, automated systems for performing the method thereof and computer readable media encoding the method thereof.
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    9. Image Registration and Multimodal Imaging of Reticular Pseudodrusen

      Image Registration and Multimodal Imaging of Reticular Pseudodrusen
      Purpose. To characterize reticular pseudodrusen (RPD) by using a point-to-point comparison of the reticular pattern on infrared reflectance (IR), autofluorescence (AF), and red-free (RF) images registered with en face sections of the choroid from spectral domain optical coherence tomography (SD-OCT) scans. Methods. A cross-sectional, retrospective study of all patients with the diagnosis of AMD who presented to the Doheny Retina Institute between December 2007 and November 2009 was conducted to ...
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    10. Effect of OCT volume scan density on thickness measurements in diabetic macular edema

      Effect of OCT volume scan density on thickness measurements in diabetic macular edema
      Purpose To evaluate the impact of reducing B-scan frame-sampling density on retinal thickness measurements using spectral domain optical coherence tomography (SD-OCT) in eyes with diabetic macular edema (DME). Methods We retrospectively collected OCT data for 64 eyes of 43 patients undergoing imaging for DME using the Cirrus HD-OCT 512 × 128 macular cube protocol. For each case, raw OCT data were imported into the 3D-OCTOR software, and retinal thickness maps were ...
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  2. About Srinivas R. Sadda

    Srinivas R. Sadda

    Srinivas R. Sadda, MD, Assistant Professor of Ophthalmology, Doheny Image Reading Center, Doheny Eye Institute, UCLA.

  3. Quotes

    1. With CIRRUS FastTrac, I can place a highest resolution 20x B-Scan precisely on the area I am treating at each successive visit to see the fine details of the patient’s response to treatment...It’s also very helpful for removing any eye motion from the larger cube scans without disturbing my patient flow because it works so quickly. My initial experience is that FastTrac is about 30 percent faster than other tracking methods I have used.
      In Modernized new OCT platforms span full spectrum of multi-modality imaging for glaucoma and retinal disease