1. Srinivas R. Sadda

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    1. Mentioned In 191 Articles

    2. The Retinal Disease Screening Study: Prospective Comparison of Non-Mydriatic FP and Optical Coherence Tomography for Detection of Retinal Irregularities

      The Retinal Disease Screening Study: Prospective Comparison of Non-Mydriatic FP and Optical Coherence Tomography for Detection of Retinal Irregularities
      Purpose:To compare the sensitivity of volume scanning with optical coherence tomography (OCT), to non-mydriatic fundus photography, for the detection of retinal abnormalities in asymptomatic populations. Methods:Asymptomatic subjects without known ocular disease recruited over a six-month period .For each eye, two undilated 45 fundus images, and four undilated volume OCT image sets covering the macula and optic nerve, were obtained. Fundus photographs were evaluated for abnormalities both inside and ...
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    3. Juxtapapillary Pigment Epithelium Detachment Observed in Asymptomatic Participants using Optical Coherence Tomograph

      Juxtapapillary Pigment Epithelium Detachment Observed in Asymptomatic Participants using Optical Coherence Tomograph
      Purpose. To use three-dimensional optical coherence tomography (3D-OCT) to assess the prevalence of juxtapapillary retinal pigment epithelial detachments (jPED) in an asymptomatic population. Methods. Asymptomatic participants (i.e. family members of patients) were prospectively recruited over a six-month period. Each subject completed a questionnaire prior to the acquisition of two undilated 45 fundus images and two undilated raster 3D-OCT scans (512x128) covering the macula and optic nerve from each eye ...
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    4. Characterization of Birdshot Chorioretinopathy Using Extramacular Enhanced Depth Optical Coherence Tomography

      Characterization of Birdshot Chorioretinopathy Using Extramacular Enhanced Depth Optical Coherence Tomography
      Objective To combine extramacular and enhanced depth optical coherence tomographic (OCT) scanning protocols to facilitate enhanced characterization of patients with birdshot chorioretinopathy. Methods Spectral-domain OCT images were prospectively collected from 24 eyes of 12 patients with birdshot chorioretinopathy. The images were acquired both from the macula and from 4 peripheral locations: superior and inferior to the temporal vascular arcades, nasal to the optic disc, and temporal to the macula. All ...
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    5. Optical coherence tomography device, method, and system

      Optical coherence tomography device, method, and system
      In accordance with one aspect of the present invention, an optical coherence tomography instrument comprises an eyepiece for receiving at least one eye of a user is provided; a light source that outputs light that is directed through the eyepiece into the user's eye; an interferometer configured to produce optical interference using light reflected from the user's eye; an optical detector disposed so as to detect said optical ...
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    6. Modernized new OCT platforms span full spectrum of multi-modality imaging for glaucoma and retinal disease

      Modernized new OCT platforms span full spectrum of multi-modality imaging for glaucoma and retinal disease
      ... I am treating at each successive visit to see the fine details of the patient’s response to treatment,” says SriniVas Sadda MD, Director of the Medical Retina Service at Doheny Eye Institute in Los Angeles, California. ...
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    7. Evaluation of Age-related Macular Degeneration With Optical Coherence Tomography

      Evaluation of Age-related Macular Degeneration With Optical Coherence Tomography
      Abstract: Age-related macular degeneration (AMD) is the leading cause of severe visual loss in people aged 50 years or older in the developed world. In recent years, major advances have been made in the treatment of AMD, with the introduction of anti-angiogenic agents, offering the first hope of significant visual recovery for patients with neovascular AMD. In line with these advances, a new imaging modalityoptical coherence tomography (OCT)has emerged ...
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    8. Effect Of Angle Of Incidence On Macular Thickness And Volume Measurements Obtained By Spectral-Domain Optical Coherence Tomography

      Effect Of Angle Of Incidence On Macular Thickness And Volume Measurements Obtained By Spectral-Domain Optical Coherence Tomography
      Purpose:To evaluate the effect of angle of incidence on macular thickness and volume measurements obtained by spectral-domain optical coherence tomography (SDOCT) Methods: 30 eyes from 15 healthy young subjects underwent macular cube volume scans (512 x 128 protocol) following dilation using the Cirrus SDOCT. Scans were obtained by positioning the scanning beam in the center of the dilated pupil, as well as in four eccentric positions (approximately 3 mm ...
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    9. Correlation Between Optical Coherence Tomography–Derived Assessments of Lower Tear Meniscus Parameters and Clinical Features of Dry Eye Disease

      Correlation Between Optical Coherence Tomography–Derived Assessments of Lower Tear Meniscus Parameters and Clinical Features of Dry Eye Disease
      Purpose: To measure the correlation between subjective symptom score, conventional clinical tests, and Fourier-domain optical coherence tomography (FD-OCT) of lower tear meniscus parameters in patients with dry eye disease.Methods: Eighteen patients with dry eye disease requiring medical therapy and/or punctal occlusion were recruited for this prospective, nonrandomized, observational case series. Severity of symptoms of dry eye disease was assessed using the Indiana University Dry Eye Questionnaire 2002. Clinical ...
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    10. Morphometric Spectral-Domain Optical Coherence Tomography Features of Epiretinal Membrane Correlate with Visual Acuity in Patients with Uveitis

      Morphometric Spectral-Domain Optical Coherence Tomography Features of Epiretinal Membrane Correlate with Visual Acuity in Patients with Uveitis
      ...cuity in Patients with Uveitis * Hossein Nazari^a Author Vitae], * Laurie Dustin^b, * Florian M. Heussen^a, * Srinivas Sadda^a, * Narsing A. Rao^a^, Corresponding author contact information ^, E-mail the corresponding au...
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    11. Relationship among visual field, blood flow, and neural structure measurements in glaucoma

      Relationship among visual field, blood flow, and neural structure measurements in glaucoma
      Purpose:To determine the relationship among visual field, neural structural, and blood flow measurements in glaucoma. Methods:Case-control study. Forty-seven eyes of 42 patients with perimetric glaucoma were age-matched with 27 normal eyes of 27 patients. All patients underwent Doppler Fourier-domain optical coherence tomography to measure retinal blood flow and standard glaucoma evaluation with visual field testing and quantitative structural imaging. Linear regression analysis was performed to analyze the relationship ...
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    12. Impact of scanning density on spectral domain optical coherence tomography assessments in neovascular age-related macular degeneration

      Impact of scanning density on spectral domain optical coherence tomography assessments in neovascular age-related macular degeneration
      Purpose:  To determine the effect of optical coherence tomography (OCT) B-scan density on the qualitative assessment of neovascular age-related macular degeneration (AMD). Methods:  Data were collected from 59 patients imaged with Topcon 3D OCT-1000 (128 B-scans × 512 A-scans). Custom software was used to generate less dense subsets of scans: 1/16 (eight B-scans), 1/8 (16 B-scans), 1/4 (32 B-scans) and 1/2 (64 B-scans). At each B-scan density ...
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    13. Correlation Between Optical Coherence Tomography-Derived Assessments of Lower Tear Meniscus Parameters and Clinical Features of Dry Eye Disease

      Correlation Between Optical Coherence Tomography-Derived Assessments of Lower Tear Meniscus Parameters and Clinical Features of Dry Eye Disease
      Purpose: To measure the correlation between subjective symptom score, conventional clinical tests, and Fourier-domain optical coherence tomography (FD-OCT) of lower tear meniscus parameters in patients with dry eye disease. Methods: Eighteen patients with dry eye disease requiring medical therapy and/or punctal occlusion were recruited for this prospective, nonrandomized, observational case series. Severity of symptoms of dry eye disease was assessed using the Indiana University Dry Eye Questionnaire 2002. Clinical ...
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    14. Diurnal Variation of Choroidal Thickness in Normal, Healthy Subjects Measured by Spectral Domain Optical Coherence Tomography

      Diurnal Variation of Choroidal Thickness in Normal, Healthy Subjects Measured by Spectral Domain Optical Coherence Tomography
      Purpose. To describe the pattern and magnitude of diurnal variation of choroidal thickness (CT), its relation to systemic and ocular factors, and to determine the intervisit reproducibility of diurnal patterns. Methods. A prospective study was conducted on 12 healthy volunteers who each underwent sequential ocular imaging on two separate days at five fixed, 2-hour time intervals. Spectral domain optical coherence tomography (OCT) with enhanced depth imaging and image tracking was ...
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    15. Assessment of Differential Pharmacodynamic Effects using Optical Coherence Tomography in Neovascular Age-Related Macular Degeneration

      Assessment of Differential Pharmacodynamic Effects using Optical Coherence Tomography in Neovascular Age-Related Macular Degeneration
      Purpose: To assess the differential pharmacodynamic effects of bevacizumab (Avastin), pegaptanib (Macugen), and verteporfin photodynamic therapy (PDT), using novel OCT parameters, in a recently completed phase III/IV clinical trial. Methods: Data from 122 patients participating in the Avastin (Bevacizumab) for Choroidal neovascularization (ABC) trial, were evaluated. Stratus OCT images were analyzed using custom software - changes in volume of the neurosensory retina, subretinal fluid (SRF), pigment epithelium detachment (PED), and ...
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    16. 136-150 of 191 « 1 2 ... 7 8 9 10 11 12 13 »
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  2. About Srinivas R. Sadda

    Srinivas R. Sadda

    Srinivas R. Sadda, MD, Assistant Professor of Ophthalmology, Doheny Image Reading Center, Doheny Eye Institute, UCLA.

  3. Quotes

    1. With CIRRUS FastTrac, I can place a highest resolution 20x B-Scan precisely on the area I am treating at each successive visit to see the fine details of the patient’s response to treatment...It’s also very helpful for removing any eye motion from the larger cube scans without disturbing my patient flow because it works so quickly. My initial experience is that FastTrac is about 30 percent faster than other tracking methods I have used.
      In Modernized new OCT platforms span full spectrum of multi-modality imaging for glaucoma and retinal disease