1. Srinivas R. Sadda

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    1. Mentioned In 130 Articles

    2. SWEPT-SOURCE OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY OF THE OPTIC DISK IN OPTIC NEUROPATHY

      SWEPT-SOURCE OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY OF THE OPTIC DISK IN OPTIC NEUROPATHY
      Purpose: To evaluate the optic nerve head microvasculature in eyes with acute and chronic optic neuropathies using swept-source optical coherence tomography angiography. Methods: In this cross-sectional, observational study, optical coherence tomography angiography images were obtained from the optic nerve heads of 21 eyes of 12 patients with optic disk edema, pseudoedema and atrophy, and 12 eyes of 6 healthy subjects using a 1,050-nm optical coherence tomography angiography (Topcon DRI ...
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    3. Swept-Source OCT Angiography Imaging of the Foveal Avascular Zone and Macular Capillary Network Density in Diabetic Retinopathy

      Swept-Source OCT Angiography Imaging of the Foveal Avascular Zone and Macular Capillary Network Density in Diabetic Retinopathy
      Purpose : We compared the area of the foveal avascular zone (FAZ) and macular capillary network density at different retinal layers using swept-source optical coherence tomography angiography (OCT-A) in normal individuals and patients with diabetic retinopathy (DR). Methods : Images (a 3 3 mm cube centered on the fovea) were acquired in 40 eyes of 22 normal individuals and 28 eyes of 18 patients with varying levels of DR using a swept-source ...
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    4. Retinal Capillary Network and Foveal Avascular Zone in Eyes with Vein Occlusion and Fellow Eyes Analyzed With Optical Coherence Tomography Angiography

      Retinal Capillary Network and Foveal Avascular Zone in Eyes with Vein Occlusion and Fellow Eyes Analyzed With Optical Coherence Tomography Angiography
      Purpose : To evaluate the perifoveolar retinal capillary network at different depths and to quantify the foveal avascular zone (FAZ) in eyes with retinal vein occlusion (RVO) compared with their fellow eyes and healthy controls using spectral-domain optical coherence tomography angiography (SD-OCTA). Methods : We prospectively recruited 23 patients with RVO including 15 eyes with central RVO (CRVO) and 8 eyes with branch RVO (BRVO), their fellow eyes, and 8 age-matched healthy ...
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    5. Repeatability of automated vessel density measurements using optical coherence tomography angiography

      Repeatability of automated vessel density measurements using optical coherence tomography angiography
      Aims To determine the repeatability of optical coherence tomography angiography (OCT-A)-derived automated vessel density measurements in the superficial retinal layer (SRL) and deep retinal layer (DRL) in healthy individuals. Methods 41 eyes of 21 healthy individuals were included in this study. OCT-A was performed using the NIDEK RS-3000 Advance with prototype OCT-A software. Each subject underwent two scanning sessions with 510 min in between. En face images of the ...
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    6. Image artefacts in swept-source optical coherence tomography angiography

      Image artefacts in swept-source optical coherence tomography angiography
      Purpose To describe optical coherence tomography angiography (OCTA) image artefacts in eyes with and without ocular pathologies. Methods The OCTA images of healthy subjects and patients with age-related macular degeneration, diabetic retinopathy and retinal vascular occlusions were retrospectively reviewed. All OCTA images were obtained using a swept-source OCTA instrument (Triton, Topcon). The frequency of various image artefacts including segmentation, banding, motion, projection, masking, unmasking, doubling of the retinal vessels, blink ...
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    7. Anterior Chamber Angle Morphometry Measurement Changes to Ambient Illumination Scaling in Visante Time Domain Optical Coherence Tomography

      Anterior Chamber Angle Morphometry Measurement Changes to Ambient Illumination Scaling in Visante Time Domain Optical Coherence Tomography
      Purpose : To test the effect of ambient illumination scaling on the reproducibility and reliability anterior chamber metrics using the Visante time domain optical coherence tomography (TD-OCT) instrument. Materials and methods : The inferior irido-corneal angles of 25 normal, healthy eyes were imaged twice with the Zeiss Visante TD-OCT under five strictly controlled ambient light conditions (foot candles (fc) measured with a light meter at camera/eye interface). Each eye was imaged ...
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    8. Drusen Volume as a Predictor of Disease Progression in Patients With Late Age-Related Macular Degeneration in the Fellow Eye

      Drusen Volume as a Predictor of Disease Progression in Patients With Late Age-Related Macular Degeneration in the Fellow Eye
      Purpose : Increasing drusen volume was proposed to be a predictor of disease progression in age-related macular degeneration (AMD). In patients with late AMD in one eye, the fellow eyes without neovascularization are known to be at higher risk of developing exudative AMD. We evaluated the relationship between drusen volume in these fellow eyes and their progression to late AMD. Methods : A retrospective analysis included fellow eyes with drusen associated with ...
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    9. Optical Coherence Tomography Angiography Evaluation of the Parafoveal Vasculature and Its Relationship With Ocular Factors

      Optical Coherence Tomography Angiography Evaluation of the Parafoveal Vasculature and Its Relationship With Ocular Factors
      Purpose : To determine the size and characteristics of the superficial and deep foveal avascular zone (FAZ) in healthy adults by using optical coherence tomography angiography (OCT-A), and to ascertain the effects of demographic and ocular parameters on the FAZ size. Methods : In a prospective cohort study of 117 healthy volunteers, foveal-centered 3 3mm OCT-A scans were manually graded by certified graders to determine the size of the superficial and deep ...
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    10. Quantitative Characteristics of Spectral-Domain Optical Coherence Tomography in Corresponding Areas of Increased Autofluorescence at the Margin of Geographic Atrophy in Patients With Age-Related Macular Degeneration

      Quantitative Characteristics of Spectral-Domain Optical Coherence Tomography in Corresponding Areas of Increased Autofluorescence at the Margin of Geographic Atrophy in Patients With Age-Related Macular Degeneration
      BACKGROUND AND OBJECTIVE: To evaluate the spectral-domain optical coherence tomography (SD-OCT) characteristics of the junctional zone corresponding to areas of increased autofluorescence (IAF) at the margin of geographic atrophy (GA) in patients with age-related macular degeneration (AMD). PATIENTS AND METHODS: SD-OCT and fundus autofluorescence (FAF) images from untreated eyes with GA available from archived studies at Doheny Image Reading Center were evaluated. Areas of definite decreased autofluorescence (DDAF) corresponding to ...
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    11. Quantification of Ellipsoid Zone Changes in Retinitis Pigmentosa Using en Face Spectral Domain–Optical Coherence Tomography

      Quantification of Ellipsoid Zone Changes in Retinitis Pigmentosa Using en Face Spectral Domain–Optical Coherence Tomography
      Importance New methods are needed to quantify the change in the outer retinal structures in retinitis pigmentosa (RP). Objective To implement an alternate method for tracking ellipsoid zone (EZ) changes in RP by quantifying the EZ area on en face spectral domainoptical coherence tomographic (SD-OCT) images. Design, Setting, and Participants Data for this observational case study were collected at the Department of Ophthalmology, University of California, Los Angeles, from May ...
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    12. Effects of Light Variation on Schwalbe's Line-based Anterior Chamber Angle Metrics Measured with Cirrus Spectral Domain Optical Coherence Tomography

      Effects of Light Variation on Schwalbe's Line-based Anterior Chamber Angle Metrics Measured with Cirrus Spectral Domain Optical Coherence Tomography
      Background Evaluate the impact of variations in ambient lighting conditions on the reproducibility/reliability of Schwalbe's Line (SL)-based anterior chamber angle (ACA) metrics using spectral domain optical coherence tomography (SD-OCT). Design Images were taken at Doheny Eye Centers-UCLA clinic, which were randomized, masked, and graded twice by dual reading center graders. Participants 25 normal/healthy participants with open-angles Methods Inferior angles were imaged using Cirrus SD-OCT under five ...
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    13. Systems and methods for automated classification of abnormalities in optical coherence tomography images of the eye

      Systems and methods for automated classification of abnormalities in optical coherence tomography images of the eye
      Systems and methods for classifying abnormalities within optical coherence tomography images of the eye are presented. One embodiment of the present invention is the classification of pigment epithelial detachments (PEDs) based on characteristics of their internal reflectivity, size and shape. The classification can be based on selected subsets of the data located within or surrounding the abnormalities. Training data can be used to generate the classification scheme and the classification ...
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    14. 1-15 of 130 1 2 3 4 5 6 7 8 9 »
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  2. About Srinivas R. Sadda

    Srinivas R. Sadda

    Srinivas R. Sadda, MD, Assistant Professor of Ophthalmology, Doheny Image Reading Center, Doheny Eye Institute, Keck School of Medicine of the University of Southern California.

  3. Quotes

    1. With CIRRUS FastTrac, I can place a highest resolution 20x B-Scan precisely on the area I am treating at each successive visit to see the fine details of the patient’s response to treatment...It’s also very helpful for removing any eye motion from the larger cube scans without disturbing my patient flow because it works so quickly. My initial experience is that FastTrac is about 30 percent faster than other tracking methods I have used.
      In Modernized new OCT platforms span full spectrum of multi-modality imaging for glaucoma and retinal disease