1. Srinivas R. Sadda

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    1. Mentioned In 121 Articles

    2. Quantification of Ellipsoid Zone Changes in Retinitis Pigmentosa Using en Face Spectral Domain–Optical Coherence Tomography

      Quantification of Ellipsoid Zone Changes in Retinitis Pigmentosa Using en Face Spectral Domain–Optical Coherence Tomography
      Importance New methods are needed to quantify the change in the outer retinal structures in retinitis pigmentosa (RP). Objective To implement an alternate method for tracking ellipsoid zone (EZ) changes in RP by quantifying the EZ area on en face spectral domainoptical coherence tomographic (SD-OCT) images. Design, Setting, and Participants Data for this observational case study were collected at the Department of Ophthalmology, University of California, Los Angeles, from May ...
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    3. Effects of Light Variation on Schwalbe's Line-based Anterior Chamber Angle Metrics Measured with Cirrus Spectral Domain Optical Coherence Tomography

      Effects of Light Variation on Schwalbe's Line-based Anterior Chamber Angle Metrics Measured with Cirrus Spectral Domain Optical Coherence Tomography
      Background Evaluate the impact of variations in ambient lighting conditions on the reproducibility/reliability of Schwalbe's Line (SL)-based anterior chamber angle (ACA) metrics using spectral domain optical coherence tomography (SD-OCT). Design Images were taken at Doheny Eye Centers-UCLA clinic, which were randomized, masked, and graded twice by dual reading center graders. Participants 25 normal/healthy participants with open-angles Methods Inferior angles were imaged using Cirrus SD-OCT under five ...
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    4. Systems and methods for automated classification of abnormalities in optical coherence tomography images of the eye

      Systems and methods for automated classification of abnormalities in optical coherence tomography images of the eye
      Systems and methods for classifying abnormalities within optical coherence tomography images of the eye are presented. One embodiment of the present invention is the classification of pigment epithelial detachments (PEDs) based on characteristics of their internal reflectivity, size and shape. The classification can be based on selected subsets of the data located within or surrounding the abnormalities. Training data can be used to generate the classification scheme and the classification ...
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    5. Predicting Development of Glaucomatous Visual Field Conversion Using Baseline Fourier-Domain Optical Coherence Tomography

      Predicting Development of Glaucomatous Visual Field Conversion Using Baseline Fourier-Domain Optical Coherence Tomography
      Purpose To predict the development of glaucomatous visual field (VF) defects using Fourier-domain optical coherence tomography (FD-OCT) measurements at baseline visit. Design Multi-center longitudinal observational study. Glaucoma suspects and pre-perimetric glaucoma participants in the Advanced Imaging for Glaucoma Study. Methods The optic disc, the peripapillary retinal nerve fiber layer (NFL), and macular ganglion cell complex (GCC) were imaged with FD-OCT VF was assessed every 6 months. Conversion to perimetric glaucoma ...
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    6. Assessing Deep Retinal Capillary Ischemia in Paracentral Acute Middle Maculopathy by Optical Coherence Tomography Angiography

      Assessing Deep Retinal Capillary Ischemia in Paracentral Acute Middle Maculopathy by Optical Coherence Tomography Angiography
      Purpose To assess microvascular blood flow of the deep retinal capillary plexus in eyes with paracentral acute middle maculopathy using optical coherence tomography (OCT) angiography. Design Retrospective, multicenter, observational case series. Methods Clinical and multimodal imaging findings from 8 patients with paracentral acute middle maculopathy were reviewed and analyzed. OCT angiography scans were analyzed and processed, and vessel density was calculated. Results Eight patients (7 male, 1 female, aged 9-82 ...
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    7. Comparison of macular choroidal thicknesses from swept source and spectral domain optical coherence tomography

      Comparison of macular choroidal thicknesses from swept source and spectral domain optical coherence tomography
      Background Choroidal thickness (CT) measurements differ between swept source optical coherence tomography (SS-OCT) and spectral domain OCT (SD-OCT) devices for point thickness measurements. We aimed to assess the comparability of mean macular CT measurements between SS-OCT and SD-OCT devices. Methods In a prospective cohort study of 25 healthy volunteers, OCT scans were performed sequentially with the deep range imaging (DRI) OCT-1 and Spectralis OCT using standardised imaging protocols. These OCT ...
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    8. Optical Coherence Tomography Angiography Of Type 3 Neovascularization Secondary To AGE-RELATED Macular Degeneration

      Optical Coherence Tomography Angiography Of Type 3 Neovascularization Secondary To AGE-RELATED Macular Degeneration
      Purpose: To characterize the vascular structure of Type 3 neovascularization secondary to age-related macular degeneration using optical coherence tomography angiography. Methods: Optical coherence tomography angiography cube scans (3 mm 3 mm) were acquired in 29 eyes of 24 patients with Type 3 lesions secondary to age-related macular degeneration using the RTVue XR Avanti with AngioVue, Split-spectrum amplitude-decorrelation, and motion correction technology. Automated layer segmentation boundaries were adjusted to best visualize ...
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    9. Evaluation of objective vitritis grading method using optical coherence tomography: influence of phakic status and previous vitrectomy - American Journal of Ophthalmology

      Evaluation of objective vitritis grading method using optical coherence tomography: influence of phakic status and previous vitrectomy - American Journal of Ophthalmology
      Purpose To evaluate a proposed method for objective measurement of vitreous inflammation using an spectral domain optical coherence tomography (SD-OCT) device in a large cohort of uveitis eyes, including pseudophakic eyes and vitrectomized eyes. Design Retrospective, observational, cohort study. Methods One-hundred five uveitis eyes (105 patients) with different vitreous haze score grades according to standardized protocols and corresponding SD-OCT images (Cirrus HD-OCT, Carl Zeiss Meditec) were included. Clinical data recorded ...
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    10. OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY IN RETINAL ARTERY OCCLUSION

      OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY IN RETINAL ARTERY OCCLUSION
      Purpose: To describe the retinal microvasculature of the eyes with nonarteritic retinal artery occlusion (RAO) based on optical coherence tomography angiography. Methods: Cross-sectional, prospective, observational study performed from September 2014 through February 2015. En face projection of optical coherence tomography angiography images centered at the macula and optic disk of the eyes presenting with RAO were acquired using the RTVue XR Avanti with AngioVue software. Qualitative analysis of the morphology ...
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    11. SUBRETINAL NEOVASCULARIZATION IN MACULAR TELANGIECTASIA TYPE 2: OPTICAL COHERENCE TOMOGRAPHIC ANGIOGRAPHY AND TREATMENT RESPONSE

      SUBRETINAL NEOVASCULARIZATION IN MACULAR TELANGIECTASIA TYPE 2: OPTICAL COHERENCE TOMOGRAPHIC ANGIOGRAPHY AND TREATMENT RESPONSE
      Purpose: To report the optical coherence tomographic angiography findings and response to treatment in a case of macular telangiectasia Type 2 with subretinal neovascularization. Methods: Case report. Results: A 64-year-old man with macular telangiectasia Type 2 developed subretinal neovascularization, which was imaged on optical coherence tomographic angiography. He was treated with intravitreal aflibercept, and there was a remarkable reduction of flow in the subretinal neovascular network on optical coherence tomographic ...
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    12. Agreement in Quantitative Anterior Chamber Angle Metrics between RTVue and Cirrus Spectral Domain Optical Coherence Tomography

      Agreement in Quantitative Anterior Chamber Angle Metrics between RTVue and Cirrus Spectral Domain Optical Coherence Tomography
      Purpose: To investigate the agreement between two spectral domain optical coherence tomography (SD-OCT) instruments in Schwalbes line (SL) based anterior chamber angle parameters and to evaluate their repeatability and reproducibility. Methods: The inferior irido-corneal angle of 114 eyes from 59 participants (29 glaucoma and 30 normal) were scanned twice with the Optovue SD-OCT and Cirrus SD-OCT under controlled low luminance conditions. SL angle opening distance (SL-AOD) and SL trabecular-iris-space area ...
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    13. EN FACE OPTICAL COHERENCE TOMOGRAPHY OF MACULAR MICROCYSTS DUE TO OPTIC NEUROPATHY FROM NEUROMYELITIS OPTICA

      EN FACE OPTICAL COHERENCE TOMOGRAPHY OF MACULAR MICROCYSTS DUE TO OPTIC NEUROPATHY FROM NEUROMYELITIS OPTICA
      Purpose: To describe the multimodal imaging, including en face optical coherence tomography (OCT) and OCT angiography, findings of a case of macular microcysts associated with neuromyelitis optica. Methods: Findings on clinical examination, color fundus photography, fluorescein angiography, fundus autofluorescence, visual fields, and OCT including en face OCT and OCT angiography are presented. Results: A 12-year-old African American boy presented with bilateral optic atrophy from neuromyelitis optica. Clinical examination was notable ...
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  2. About Srinivas R. Sadda

    Srinivas R. Sadda

    Srinivas R. Sadda, MD, Assistant Professor of Ophthalmology, Doheny Image Reading Center, Doheny Eye Institute, Keck School of Medicine of the University of Southern California.

  3. Quotes

    1. With CIRRUS FastTrac, I can place a highest resolution 20x B-Scan precisely on the area I am treating at each successive visit to see the fine details of the patient’s response to treatment...It’s also very helpful for removing any eye motion from the larger cube scans without disturbing my patient flow because it works so quickly. My initial experience is that FastTrac is about 30 percent faster than other tracking methods I have used.
      In Modernized new OCT platforms span full spectrum of multi-modality imaging for glaucoma and retinal disease