1. Srinivas R. Sadda

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    1. Mentioned In 197 Articles

    2. Subtype-differentiated impacts of subretinal drusenoid deposits on photoreceptors revealed by adaptive optics scanning laser ophthalmoscopy

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      Subtype-differentiated impacts of subretinal drusenoid deposits on photoreceptors revealed by adaptive optics scanning laser ophthalmoscopy
      Purpose To examine the structure of photoreceptors surrounding two subtypes of subretinal drusenoid deposits (SDD), namely, dot and ribbon SDD, using multimodal imaging including adaptive optics scanning laser ophthalmoscopy (AOSLO) and spectral-domain optical coherence tomography (SD-OCT). Methods Twenty-six eyes of 13 patients with age-related macular degeneration (AMD) and SDD and 16 eyes of 8 subjects in normal chorioretinal health were studied. SDD presence, stage, and subtype were determined using color ...
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      Mentions: Srinivas R. Sadda Yuhua Zhang UCLA

    3. Thresholding strategies to measure vessel density by optical coherence tomography angiography

      Explore ScienceDirect Ophthalmology
      Thresholding strategies to measure vessel density by optical coherence tomography angiography
      Objective A variety of binarization strategies have been used to measure vessel density by optical coherence tomography angiography (OCT-A), but it is uncertain if they produce similar results. The purpose of the study was to evaluate the impact of different thresholding methods and contrast and brightness adjustment on OCT-A vessel density metrics. Design Observational, cross-sectional case series. Participants Consecutive healthy volunteers. Methods Healthy volunteers underwent fovea-centred 3 mm 3 mm ...
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      Mentions: Srinivas R. Sadda University of Milan UCLA

    4. Optimizing the Repeatability of Choriocapillaris Flow Deficit Measurement from Optical Coherence Tomography Angiography

      Explore American Journal of Ophthalmology Ophthalmology
      Optimizing the Repeatability of Choriocapillaris Flow Deficit Measurement from Optical Coherence Tomography Angiography
      Purpose To evaluate impact of processing technique and slab selection on the repeatability of choriocapillaris (CC) flow deficit (FD) measurements as assessed using optical coherence tomography angiography (OCTA) Design: prospective, cross-sectional study Methods Healthy subjects were imaged with four consecutive 3x3mm OCTA using a swept source OCT (PLEX elite 9000, Carl Zeiss Meditec, Dublin, CA). OCTA images were generated using the Max projection, and three 10 m-thick slabs starting 11 ...
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      Mentions: Carl Zeiss Meditec Srinivas R. Sadda UCLA

    5. Effect of image averaging on optical coherence tomography angiography data in eyes with branch retinal vein occlusion

      Explore Home - Springer Ophthalmology
      Effect of image averaging on optical coherence tomography angiography data in eyes with branch retinal vein occlusion
      Purpose To investigate the effect of image averaging on qualitative and quantitative assessments of optical coherence tomography angiography (OCTA) images from eyes of patients with branch retinal vein occlusion (BRVO). Methods Macular OCTA images of 33 eyes of 33 patients with BRVO were obtained using the HS100 HR-SD-OCT system (Canon, Inc.). For each eye, five OCTA cube scans were obtained with a 33 mm scan protocol, and the data were ...
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      Mentions: Srinivas R. Sadda Akitaka Tsujikawa UCLA

    6. Reproducibility and agreement of four anterior segment-optical coherence tomography devices for anterior chamber angle measurements

      Explore Home - Springer Ophthalmology
      Reproducibility and agreement of four anterior segment-optical coherence tomography devices for anterior chamber angle measurements
      Purpose To compare the reproducibility and agreement of anterior chamber angle (ACA) parameters and metrics obtained by four different anterior segment-optical coherence tomography (AS-OCT) devices. Methods In this prospective study, 30 eyes from 15 normal subjects underwent anterior segment angle scanning using the Spectralis, Cirrus, and Optovue spectral domain optical coherence tomography (SD-OCT), as well as the Visante time-domain optical coherence tomography (TD-OCT). For each eye, the scan line was ...
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      Mentions: Optovue Srinivas R. Sadda UCLA

    7. Quantitative assessment of the retinal microvasculature and choriocapillaris in myopic patients using swept-source optical coherence tomography angiography

      Explore Home - Springer Ophthalmology
      Quantitative assessment of the retinal microvasculature and choriocapillaris in myopic patients using swept-source optical coherence tomography angiography
      Purpose To study the retinal capillary microvasculature and the choriocapillaris (CC) in myopic eyes using swept-source optical coherence tomography angiography (SS-OCTA). Methods Patients with high myopia (6D; axial length26.5 mm), moderate myopia (3D, 6D), and age-matched healthy subjects presenting to the Shanghai General Hospital and Doheny-UCLA Eye Centers were enrolled in this prospective, multicenter study. Any subjects with evidence of macular abnormalities suggestive of pathologic myopia were excluded. SS-OCTA ...
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      Mentions: Srinivas R. Sadda UCLA Shanghai Jiao Tong University

    8. Appearance of cysts and capillary non perfusion areas in diabetic macular edema using two different OCTA devices

      Explore Nature Publishing Group Ophthalmology
      Appearance of cysts and capillary non perfusion areas in diabetic macular edema using two different OCTA devices
      The aim of this paper was to distinguish the appearance of cysts and non-perfusion areas (NPAs) in diabetic macular edema (DME) using two different Optical Coherence Tomography Angiography (OCTA) devices. In this study, patients underwent OCTA using the AngioVue XR Avanti Spectral Domain (SD) OCTA and the PLEX Elite 9000 Swept-Source (SS) OCTA. Foveal and extrafoveal regions of interest (ROI), defined as any area with an altered flow signal comparing ...
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      Mentions: Optovue Srinivas R. Sadda Giuseppe Querques

    10. Pearls and Pitfalls of Optical Coherence Tomography Angiography Image Interpretation

      Explore The JAMA Network Ophthalmology
      Pearls and Pitfalls of Optical Coherence Tomography Angiography Image Interpretation
      The advent of optical coherence tomography angiography (OCTA), a relatively new tool to image the retinal and choroidal microvasculature with depth-resolved capability, has been met with great excitement by some ophthalmologists. This noninvasive technology is a potentially valuable instrument to differentiate flow impairment in the superficial vs deep retinal capillary plexus, and it can quantify nonperfusion in eyes with retinal vascular disease. Moreover, OCTA has advanced understanding of the microvascular ...
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      Mentions: Srinivas R. Sadda UCLA

    11. Effect of Choroidal Vessel Density on the Ellipsoid Zone and Visual Function in Retinitis Pigmentosa Using Optical Coherence Tomography Angiography

      Explore IOVS Journal
      Effect of Choroidal Vessel Density on the Ellipsoid Zone and Visual Function in Retinitis Pigmentosa Using Optical Coherence Tomography Angiography
      Purpose : We evaluate the effect of choroidal vessel density on the residual length of the ellipsoid zone (EZ) and visual function in patients with retinitis pigmentosa (RP) using optical coherence tomography angiography (OCTA). Methods : Fifty-three patients with RP ( n = 101 eyes) and 53 normal participants ( n = 76 eyes) were enrolled in this study. Patients with RP were assigned to three groups according to their best-corrected visual acuity (BCVA). All patients ...
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      Mentions: Sun Yat-Sen University Srinivas R. Sadda

    13. Impact of slab selection on quantification of choriocapillaris flow deficits by optical coherence tomography angiography

      Explore American Journal of Ophthalmology Ophthalmology
      Impact of slab selection on quantification of choriocapillaris flow deficits by optical coherence tomography angiography
      Purpose To assess the impact of slab selection on quantitative measurements of choriocapillaris (CC) flow deficits (FDs) using optical coherence tomography angiography (OCTA). Design Cross-sectional study Methods Using a swept-source OCTA device, en face slabs to isolate the CC were first generated using the manufacturers default setting: a 20 m-thick slab starting 29 m posterior to the centerline of the automatically segmented retinal pigment epithelium (RPE) band. The inner and ...
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      Mentions: Srinivas R. Sadda UCLA

    14. Volumetric Analysis of Vascularized Serous Pigment Epithelial Detachment Progression in Neovascular Age-Related Macular Degeneration Using Optical Coherence Tomography Angiography

      Explore IOVS Journal Ophthalmology
      Volumetric Analysis of Vascularized Serous Pigment Epithelial Detachment Progression in Neovascular Age-Related Macular Degeneration Using Optical Coherence Tomography Angiography
      Purpose : To analyze the evolution of type 1 neovascularization associated with vascularized serous pigment epithelial detachment (vsPED) using three-dimensional, volumetric, en face optical coherence tomography angiography (OCTA). Methods : This was a retrospective case series from four tertiary medical centers. OCTA images were analyzed at baseline and at the 3-, 6-, 12-, 18-, and 24-month follow-up visit when available. Visual acuity, number of injections, PED maximal height and PED area and ...
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      Mentions: Tufts University Srinivas R. Sadda Giuseppe Querques

    15. Baseline Spectral Domain Optical Coherence Tomography Characteristics of Age-Related Macular Degeneration

      Explore LWW Online Ophthalmology
      Baseline Spectral Domain Optical Coherence Tomography Characteristics of Age-Related Macular Degeneration
      Purpose: To describe spectral domain optical coherence tomography (SD-OCT) findings in an Amish cohort to assess SD-OCT markers for early age-related macular degeneration (AMD). Methods: The authors performed a family-based prospective cohort study of 1,146 elderly Amish subjects (age range 5099 years) (2,292 eyes) who had a family history of at least 1 individual with AMD. All subjects underwent complete ophthalmic examinations, SD-OCT using both Cirrus and Spectralis ...
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      Mentions: Case Western Reserve University University of Pennsylvania Srinivas R. Sadda

    16. Retinal Vascular Changes During Pregnancy Detected With Optical Coherence Tomography Angiograph

      Explore IOVS Journal Ophthalmology
      Retinal Vascular Changes During Pregnancy Detected With Optical Coherence Tomography Angiograph
      Purpose : To evaluate retinal vascular status during pregnancy by using optical coherence tomography angiography (OCTA). Methods : Women in their third trimester of pregnancy and nonpregnant age-matched women were recruited for this prospective, case-control study. Subjects were imaged with OCTA. Main outcome measures were foveal avascular zone parameters, perfusion density (PD) percentage in the superficial retinal capillary plexus (SCP), PD percentage in the deep retinal capillary plexus (DCP), SCP vessel length ...
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      Mentions: Srinivas R. Sadda UCLA
    17. 1-15 of 197 1 2 3 4 ... 11 12 13 »
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  4. About Srinivas R. Sadda

    Srinivas R. Sadda

    Srinivas R. Sadda, MD, Assistant Professor of Ophthalmology, Doheny Image Reading Center, Doheny Eye Institute, UCLA.

  5. Related Topics

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    3. Comparison of the Optical Coherence Tomographic Features of Choroidal Neovascular Membranes in Pathologic Myopia versus Age-Related Macular Degeneration, using Quantitative Subanalysis
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  6. Quotes

    1. With CIRRUS FastTrac, I can place a highest resolution 20x B-Scan precisely on the area I am treating at each successive visit to see the fine details of the patient’s response to treatment...It’s also very helpful for removing any eye motion from the larger cube scans without disturbing my patient flow because it works so quickly. My initial experience is that FastTrac is about 30 percent faster than other tracking methods I have used.
      In Modernized new OCT platforms span full spectrum of multi-modality imaging for glaucoma and retinal disease