1. Srinivas R. Sadda

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    1. Mentioned In 153 Articles

    2. Repeatability and Reproducibility of Superficial Macular Retinal Vessel Density Measurements Using Optical Coherence Tomography Angiography En Face Images

      Explore The JAMA Network Ophthalmology
      Repeatability and Reproducibility of Superficial Macular Retinal Vessel Density Measurements Using Optical Coherence Tomography Angiography En Face Images
      Importance The repeatability and reproducibility of quantitative metrics from optical coherence tomographic angiography (OCTA) must be assessed before these data can be confidently interpreted in clinical research and practice. Objective To evaluate the repeatability and reproducibility of OCTA-derived retinal vascular quantitative metrics. Design, Setting and Participants In this cross-sectional study, 21 healthy volunteers (42 eyes) and 22 patients with retinal disease (22 eyes), including 14 with age-related macular degeneration, 3 ...
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      Mentions: University of Southern California Carl Zeiss Meditec Srinivas R. Sadda

    3. CLASSIFICATION AND QUANTITATIVE ANALYSIS OF GEOGRAPHIC ATROPHY JUNCTIONAL ZONE USING SPECTRAL DOMAIN OPTICAL COHERENCE TOMOGRAPHY

      Explore LWW Online Ophthalmology
      CLASSIFICATION AND QUANTITATIVE ANALYSIS OF GEOGRAPHIC ATROPHY JUNCTIONAL ZONE USING SPECTRAL DOMAIN OPTICAL COHERENCE TOMOGRAPHY
      Purpose: The junctional zone at the border of areas of geographic atrophy (GA) in eyes with nonneovascular age-related macular degeneration is an important target region for future therapeutic strategies. The goal of this study was to perform a detailed classification and quantitative characterization of the junctional zone using spectral domain optical coherence tomography. Methods: Spectral domain optical coherence tomography volume cube scans (Spectralis OCT, 1024 x 37, Automatic Real Time ...
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      Mentions: Srinivas R. Sadda UCSF

    4. Quantitative Features of the Choriocapillaris in Healthy Individuals Using Swept-Source Optical Coherence Tomography Angiography

      Explore Healio.com Ophthalmology
      Quantitative Features of the Choriocapillaris in Healthy Individuals Using Swept-Source Optical Coherence Tomography Angiography
      BACKGROUND AND OBJECTIVE: To quantify vessel density (VD) and grey value (GV) as a measure of flow in the choriocapillaris (CC) in healthy subjects with optical coherence tomography angiography (OCTA). PATIENTS AND METHODS: In this prospective, noncomparative case series, 3 mm 3 mm OCTA images of 36 eyes of 22 healthy individuals were obtained using a swept-source instrument. VD and GV levels were calculated on CC en face slabs in ...
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      Mentions: Carl Zeiss Meditec University of Bonn David Geffen School of Medicine

    6. Spectral Domain Optical Coherence Tomography in Macular Disease (Textbook)

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      Spectral Domain Optical Coherence Tomography in Macular Disease (Textbook)
      . This book aims to build concepts and create a solid foundation in the field of optical coherence tomography (OCT) for the general ophthalmologists as well as for the resident trainees and fellows. The chapters are written by leading international authorities in a style comprehensible to a broad audience. Numerous clinical pictures and SD-OCT scans help elucidate various clinical entities.OCT is the optical analog of ultrasound imaging and has emerged ...
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      Mentions: Srinivas R. Sadda Sandeep Saxena UCLA

    7. Proposal of a simple optical coherence tomography-based scoring system for progression of age-related macular degeneration

      Explore Home - Springer Ophthalmology
      Proposal of a simple optical coherence tomography-based scoring system for progression of age-related macular degeneration
      Purpose To develop a simple, clinically practical, optical coherence tomography (OCT)-based scoring system for early age-related macular degeneration (AMD) to prognosticate risk for progression to late AMD. Methods We retrospectively reviewed OCT images (512 128 macular cube, Cirrus) from 138 patients diagnosed of early AMD in at least one eye and follow-up of at least 12 months. For patients with early AMD in both eyes, only the right eye ...
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      Mentions: Srinivas R. Sadda UCLA

    8. BIOMARKERS OF NEOVASCULAR ACTIVITY IN AGE-RELATED MACULAR DEGENERATION USING OCT ANGIOGRAPHY

      Explore LWW Online Ophthalmology
      BIOMARKERS OF NEOVASCULAR ACTIVITY IN AGE-RELATED MACULAR DEGENERATION USING OCT ANGIOGRAPHY
      Purpose: To study the qualitative and quantitative features of choroidal neovascular (NV) membranes in age-related macular degeneration using optical coherence tomography angiography in patients with active and quiescent NV lesions before and after treatment with anti-vascular endothelial growth factor. Methods: Macular optical coherence tomography angiography images were obtained using RTVue XR Avanti with AngioVue. Morphologic features and quantitative measurements of the NV lesion were analyzed using en face projection images ...
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      Mentions: Srinivas R. Sadda UCLA

    9. Choroidal Imaging with Swept-Source Optical Coherence Tomography in Patients with Birdshot Chorioretinopathy

      Explore Ophthalmology Ophthalmology
      Choroidal Imaging with Swept-Source Optical Coherence Tomography in Patients with Birdshot Chorioretinopathy
      Purpose To characterize choroidal thickness and choroidal reflectivity in the eyes of patients with birdshot chorioretinopathy (BSCR). Design Cross-sectional observational study. Participants Two hundred twenty BSCR patients and 59 healthy controls. Methods Patients with BSCR and healthy controls underwent imaging of the macula in both eyes with a swept-source optical coherence tomography device (DRI-OCT1 Atlantis; Topcon). Images were exported from the device, and analysis was performed by 2 graders in ...
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      Mentions: Srinivas R. Sadda UCLA

    10. Impact of Multiple En Face Image Averaging on Quantitative Assessment from Optical Coherence Tomography Angiography Images

      Explore Elsevier Health Ophthalmology
      Impact of Multiple En Face Image Averaging on Quantitative Assessment from Optical Coherence Tomography Angiography Images
      Purpose To investigate the impact of multiple en face image averaging on quantitative measurements of the retinal microvasculature using optical coherence tomography angiography (OCTA). Design Prospective, observational, cross-sectional case series. Participants Twenty-one healthy individuals with normal eyes. Methods Macular OCTA images were acquired from all participants using the Zeiss Cirrus 5000 with Angioplex OCTA software (Carl Zeiss Meditec, Dublin, CA). Nine OCTA cube scans per eye were obtained and 9 ...
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      Mentions: Srinivas R. Sadda UCSF

    11. Variability of Retinal Thickness Measurements in Tilted or Stretched Optical Coherence Tomography Images

      Explore TVST Journal Ophthalmology
      Variability of Retinal Thickness Measurements in Tilted or Stretched Optical Coherence Tomography Images
      Purpose : To investigate the level of inaccuracy of retinal thickness measurements in tilted and axially stretched optical coherence tomography (OCT) images. Methods : A consecutive series of 50 eyes of 50 patients with age-related macular degeneration were included in this study, and Cirrus HD-OCT images through the foveal center were used for the analysis. The foveal thickness was measured in three ways: (1) parallel to the orientation of the A-scan (Tx ...
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      Mentions: Srinivas R. Sadda UCLA

    12. QUANTIFICATION OF INTRARETINAL HARD EXUDATES IN EYES WITH DIABETIC RETINOPATHY BY OPTICAL COHERENCE TOMOGRAPHY

      Explore LWW Online Ophthalmology
      QUANTIFICATION OF INTRARETINAL HARD EXUDATES IN EYES WITH DIABETIC RETINOPATHY BY OPTICAL COHERENCE TOMOGRAPHY
      Purpose: To evaluate the reproducibility of intraretinal hard exudate (HE) quantification from spectral domain optical coherence tomography (SD-OCT) images of eyes with diabetic retinopathy (DR). Methods: Cases with diabetic macular edema were enrolled. The area of HE obtained by B-scan segmentation was compared with the area obtained by en face segmentation. Results: The mean +/- SD for the HE area was 1.78 +/- 1.37 mm2 with B-scan segmentation and 0 ...
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      Mentions: University of Bonn Srinivas R. Sadda UCLA

    13. En Face OCT Analysis to Assess the Spectrum of Perivenular Ischemia and Paracentral Acute Middle Maculopathy in Retinal Vein Occlusion

      Explore Elsevier Health Ophthalmology
      En Face OCT Analysis to Assess the Spectrum of Perivenular Ischemia and Paracentral Acute Middle Maculopathy in Retinal Vein Occlusion
      Purpose To assess the spectrum of perivenular ischemia in eyes with retinal vascular obstruction (typically central or hemicentral retinal vein obstruction) using en face optical coherence tomography (OCT). Design Retrospective observational case series. Methods Eyes with recent retinal vascular occlusion illustrating paracentral acute middle maculopathy (PAMM) in a perivenular fern-like pattern with en face OCT were evaluated in this study. Multimodal retinal imaging including en face OCT segmentation of the ...
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      Mentions: Richard B. Rosen Srinivas R. Sadda UCLA

    14. Optical coherence tomography angiography of the optic disc; an overview

      Explore jovr.org Ophthalmology
      Optical coherence tomography angiography of the optic disc; an overview
      Different diseases of the optic disc may be caused by or lead to abnormal vasculature at the optic nerve head. Optical coherence tomography angiography (OCTA) is a novel technology that provides high resolution mapping of the retinal and optic disc vessels. Recent studies have shown the ability of OCTA to visualize vascular abnormalities in different optic neuropathies. In addition, quantified OCTA measurements were found promising for differentiating optic neuropathies from ...
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      Mentions: Srinivas R. Sadda UCLA

    15. Semiautomated segmentation and analysis of retinal layers in three-dimensional spectral-domain optical coherence tomography images of patients with atrophic age-related macular degeneration

      Explore SPIE | Journal Neurology , Ophthalmology
      Semiautomated segmentation and analysis of retinal layers in three-dimensional spectral-domain optical coherence tomography images of patients with atrophic age-related macular degeneration
      Historically, regular drusen and geographic atrophy (GA) have been recognized as the hallmarks of nonneovascular age-related macular degeneration (AMD). Recent imaging developments have revealed another distinct nonneovascular AMD phenotype, reticular pseudodrusen (RPD). We develop an approach to semiautomatically quantify retinal surfaces associated with various AMD lesions (i.e., regular drusen, RPD, and GA) in spectral domain (SD) optical coherence tomography (OCT) images. More specifically, a graph-based algorithm was used to ...
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      Mentions: Srinivas R. Sadda UCLA Zhihong Hu

    16. Retinal vessel density from optical coherence tomography angiography to differentiate early glaucoma, pre-perimetric glaucoma and normal eyes

      Explore Journals | PLOS Ophthalmology
      Retinal vessel density from optical coherence tomography angiography to differentiate early glaucoma, pre-perimetric glaucoma and normal eyes
      Purpose To evaluate optic nerve vascular density using swept source optical coherence tomography angiography (OCTA) in patients with early primary open angle glaucoma (POAG), pre-perimetric glaucoma and normal eyes. Methods This is a prospective, observational study including 56 eyes in total and divided into 3 groups; 20 eyes with mild POAG, 20 pre-perimetric glaucoma eyes, and 16 age-matched normal eyes as controls. The optic disc region was imaged by a ...
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      Mentions: Topcon Medical Systems Carl Zeiss Meditec Srinivas R. Sadda
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  4. About Srinivas R. Sadda

    Srinivas R. Sadda

    Srinivas R. Sadda, MD, Assistant Professor of Ophthalmology, Doheny Image Reading Center, Doheny Eye Institute, Keck School of Medicine of the University of Southern California.

  5. Related Topics

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    2. Association Of The Extent Of Diabetic Macular Edema As Assessed By Optical Coherence Tomography With Visual Acuity And Retinal Outcome Variables.
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    3. Comparison of the Optical Coherence Tomographic Features of Choroidal Neovascular Membranes in Pathologic Myopia versus Age-Related Macular Degeneration, using Quantitative Subanalysis
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  6. Quotes

    1. With CIRRUS FastTrac, I can place a highest resolution 20x B-Scan precisely on the area I am treating at each successive visit to see the fine details of the patient’s response to treatment...It’s also very helpful for removing any eye motion from the larger cube scans without disturbing my patient flow because it works so quickly. My initial experience is that FastTrac is about 30 percent faster than other tracking methods I have used.
      In Modernized new OCT platforms span full spectrum of multi-modality imaging for glaucoma and retinal disease