1. Srinivas R. Sadda

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    1. Mentioned In 182 Articles

    2. Impact of slab selection on quantification of choriocapillaris flow deficits by optical coherence tomography angiography

      Explore American Journal of Ophthalmology Ophthalmology
      Impact of slab selection on quantification of choriocapillaris flow deficits by optical coherence tomography angiography
      Purpose To assess the impact of slab selection on quantitative measurements of choriocapillaris (CC) flow deficits (FDs) using optical coherence tomography angiography (OCTA). Design Cross-sectional study Methods Using a swept-source OCTA device, en face slabs to isolate the CC were first generated using the manufacturers default setting: a 20 m-thick slab starting 29 m posterior to the centerline of the automatically segmented retinal pigment epithelium (RPE) band. The inner and ...
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      Mentions: Srinivas R. Sadda UCLA

    3. Volumetric Analysis of Vascularized Serous Pigment Epithelial Detachment Progression in Neovascular Age-Related Macular Degeneration Using Optical Coherence Tomography Angiography

      Explore IOVS Journal Ophthalmology
      Volumetric Analysis of Vascularized Serous Pigment Epithelial Detachment Progression in Neovascular Age-Related Macular Degeneration Using Optical Coherence Tomography Angiography
      Purpose : To analyze the evolution of type 1 neovascularization associated with vascularized serous pigment epithelial detachment (vsPED) using three-dimensional, volumetric, en face optical coherence tomography angiography (OCTA). Methods : This was a retrospective case series from four tertiary medical centers. OCTA images were analyzed at baseline and at the 3-, 6-, 12-, 18-, and 24-month follow-up visit when available. Visual acuity, number of injections, PED maximal height and PED area and ...
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      Mentions: Tufts University Srinivas R. Sadda Giuseppe Querques

    4. Baseline Spectral Domain Optical Coherence Tomography Characteristics of Age-Related Macular Degeneration

      Explore LWW Online Ophthalmology
      Baseline Spectral Domain Optical Coherence Tomography Characteristics of Age-Related Macular Degeneration
      Purpose: To describe spectral domain optical coherence tomography (SD-OCT) findings in an Amish cohort to assess SD-OCT markers for early age-related macular degeneration (AMD). Methods: The authors performed a family-based prospective cohort study of 1,146 elderly Amish subjects (age range 5099 years) (2,292 eyes) who had a family history of at least 1 individual with AMD. All subjects underwent complete ophthalmic examinations, SD-OCT using both Cirrus and Spectralis ...
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      Mentions: Case Western Reserve University University of Pennsylvania Srinivas R. Sadda

    5. Retinal Vascular Changes During Pregnancy Detected With Optical Coherence Tomography Angiograph

      Explore IOVS Journal Ophthalmology
      Retinal Vascular Changes During Pregnancy Detected With Optical Coherence Tomography Angiograph
      Purpose : To evaluate retinal vascular status during pregnancy by using optical coherence tomography angiography (OCTA). Methods : Women in their third trimester of pregnancy and nonpregnant age-matched women were recruited for this prospective, case-control study. Subjects were imaged with OCTA. Main outcome measures were foveal avascular zone parameters, perfusion density (PD) percentage in the superficial retinal capillary plexus (SCP), PD percentage in the deep retinal capillary plexus (DCP), SCP vessel length ...
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      Mentions: Srinivas R. Sadda UCLA

    6. Optical coherence tomography risk factors for development of late age related macular degeneration in the fellow eyes of patients enrolled in the HARBOR Study

      Explore Ophthalmology Ophthalmology
      Optical coherence tomography risk factors for development of late age related macular degeneration in the fellow eyes of patients enrolled in the HARBOR Study
      Purpose To evaluate the relationship between optical coherence tomography (OCT) features and the progression to late age related macular degeneration (AMD) in the fellow eyes of patients enrolled in the 24-month HARBOR study (NCT00891735) for neovascular AMD. Design post hoc analysis of a phase 3 multicenter, prospective, randomized, double-masked, active treatment-controlled clinical trial. Participants Evaluable subjects (N=501) with macular neovascularization (MNV) secondary to neovascular AMD and early or intermediate ...
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      Mentions: Srinivas R. Sadda UCLA

    7. Macular Microvascular Networks In Healthy Pediatric Subjects

      Explore LWW Online Ophthalmology
      Macular Microvascular Networks In Healthy Pediatric Subjects
      Purpose: To report optical coherence tomography angiography ( OCTA ) values in healthy pediatric eyes and to identify factors that may modify these values. Methods: In this prospective observational cross-sectional study, macular OCTA images were acquired from healthy pediatric patients. Main outcome measures were 1) foveal avascular zone (FAZ) area at the level of the superficial retinal capillary plexus (SCP); 2) SCP and deep retinal capillary plexus (DCP) perfusion density (based on ...
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      Mentions: Srinivas R. Sadda UCLA

    8. Pearls and Pitfalls of Optical Coherence Tomography Angiography Imaging: A Review

      Explore Home - Springer Ophthalmology
      Pearls and Pitfalls of Optical Coherence Tomography Angiography Imaging: A Review
      Optical coherence tomography angiography (OCTA) has significantly expanded our knowledge of the ocular vasculature. Furthermore, this imaging modality has been widely adopted to investigate different ocular and systemic diseases. In this review, a discussion of the fundamental principles of OCTA is followed by the application of this imaging modality to study the retinal and choroidal vessels. A proper comprehension of this imaging modality is essential for the interpretation of OCTA ...
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      Mentions: Srinivas R. Sadda Giuseppe Querques UCLA

    9. Identification and Characterization of Imaging Technique Errors and Artifacts using Anterior Segment Optical Coherence Tomography for Irido-Corneal Angle Evaluations in Glaucom

      Explore ScienceDirect Ophthalmology
      Identification and Characterization of Imaging Technique Errors and Artifacts using Anterior Segment Optical Coherence Tomography for Irido-Corneal Angle Evaluations in Glaucom
      Purpose Anterior segment optical coherence tomography (ASOCT) platforms provide non-invasive and quantifiable evaluations of anterior chamber angle (ACA) anatomy. Even though these ACA measurements have been validated with high repeatability and reproducibility, we are the first study to describe in detail the technique errors and artifacts that may occur during imaging of the ACA. The purpose of this study was to define the different types and quantify the frequency of ...
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      Mentions: Optovue Srinivas R. Sadda UCLA

    10. CORRELATION OF EN FACE OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY AVERAGING VERSUS SINGLE-IMAGE QUANTITATIVE MEASUREMENTS WITH RETINAL VEIN OCCLUSION VISUAL OUTCOMES

      Explore LWW Online Ophthalmology
      CORRELATION OF EN FACE OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY AVERAGING VERSUS SINGLE-IMAGE QUANTITATIVE MEASUREMENTS WITH RETINAL VEIN OCCLUSION VISUAL OUTCOMES
      Purpose: To demonstrate the effect of averaging multiple en face optical coherence tomography angiography images on the correlation between retinal microvasculature quantitative metrics and best-corrected visual acuity (BCVA) in eyes with retinal vein occlusion . Methods: A cross-sectional cohort with unilateral retinal vein occlusion was imaged in both eyes. Five 3 mm 3-mm spectral domain optical coherence tomography angiography images were averaged, and quantitative parameters from averaged versus single images were ...
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      Mentions: Columbia University Carl Zeiss Meditec Srinivas R. Sadda

    11. Impact of segmentation density on spectral domain optical coherence tomography assessment in Stargardt disease

      Explore Home - Springer Ophthalmology
      Impact of segmentation density on spectral domain optical coherence tomography assessment in Stargardt disease
      Purpose Automated spectral domain optical coherence tomography (SD-OCT) segmentation algorithms currently do not perform well in segmenting individual intraretinal layers in eyes with Stargardt disease (STGD). We compared selective B-scan segmentation strategies for generating mean retinal layer thickness and preserved area data from SD-OCT scans in patients with STGD1. Methods Forty-five eyes from 40 Stargardt patients were randomly selected from the ongoing Natural History of the Progression of Atrophy Secondary ...
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      Mentions: Johns Hopkins University University College London Hendrik P. N. Scholl

    12. Summary of 6th International Meeting on OCT Angiography & Advances in OCT in Rome December 2018: A Tremendous Success

      Explore Optical Coherence Tomography News
      Summary of 6th International Meeting on OCT Angiography & Advances in OCT in Rome December 2018: A Tremendous Success
      On December 14 and 15 2018, over 1400 ophthalmologists participated in Rome at tha most important meeting on OCT and OCT Angiography. the 6th international meeting on OCT Angiography, advances in OCT . The organizer, Dr Lumbroso has, since he started to organize these meetings, a well-defined objective: informing ophthalmologist in any country on the new clinical possibilities of Ocular imaging. The policy is to invite the best speakers in the ...
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      Mentions: Philip J. Rosenfeld Massachusetts Institute of Technology James G. Fujimoto

    13. Evaluation of Corneal Epithelial Thickness Imaged by High Definition Optical Coherence Tomography in Healthy Eyes

      Explore LWW Online Ophthalmology
      Evaluation of Corneal Epithelial Thickness Imaged by High Definition Optical Coherence Tomography in Healthy Eyes
      Purpose: To evaluate corneal epithelial thickness (CET) and corneal thickness (CT) in healthy eyes using spectral domain optical coherence tomography. Methods: Thirty-six healthy eyes were imaged using the Cirrus high-definition (HD)-optical coherence tomography device. The average CET and CT were assessed using Cirrus Review Software within predefined concentric corneal ring-shaped zones. Specific regions of CET (superior, inferior, temporal, nasal, superonasal, inferotemporal, superotemporal, and inferonasal) were also assessed. The difference ...
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      Mentions: Srinivas R. Sadda UCLA

    14. Evaluation of Corneal Epithelial Thickness Imaged by the High Definition Optical Coherence Tomography in Healthy Eyes

      Explore LWW Online Ophthalmology
      Evaluation of Corneal Epithelial Thickness Imaged by the High Definition Optical Coherence Tomography in Healthy Eyes
      Purpose: To evaluate corneal epithelial thickness (CET) and corneal thickness (CT) in healthy eyes using spectral domain optical coherence tomography. Methods: Thirty-six healthy eyes were imaged using the Cirrus high-definition (HD)-optical coherence tomography device. The average CET and CT were assessed using Cirrus Review Software within predefined concentric corneal ring-shaped zones. Specific regions of CET (superior, inferior, temporal, nasal, superonasal, inferotemporal, superotemporal, and inferonasal) were also assessed. The difference ...
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      Mentions: Srinivas R. Sadda UCSF

    15. VISUAL FUNCTION AND OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY FEATURES IN CHILDREN BORN PRETERM

      Explore LWW Online Ophthalmology
      VISUAL FUNCTION AND OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY FEATURES IN CHILDREN BORN PRETERM
      Purpose: Preterm children have an increased risk of impaired vision from retinopathy, strabismus, and high refractive error. The aim of this study was to investigate the relationship between foveal parameters generated by optical coherence tomography angiography and visual function in preterm children. Methods: Eighty eyes (32 eyes of former preterm infants and 48 age-matched full-term control eyes) were analyzed. Subjects underwent complete eye examinations including best-corrected visual acuity and retinal ...
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      Mentions: Optovue Srinivas R. Sadda UCLA

    16. Choriocapillaris impairment around the atrophic lesions in patients with geographic atrophy: a swept-source optical coherence tomography angiography study

      Explore BJO Online Ophthalmology
      Choriocapillaris impairment around the atrophic lesions in patients with geographic atrophy: a swept-source optical coherence tomography angiography study
      Aims To evaluate the choriocapillaris (CC) flow alterations around geographic atrophy (GA) in eyes with dry age-related macular degeneration. Methods Using a swept-source optical coherence tomography angiography (SS-OCTA) device, two volume 66 mm scans were acquired in patients with GA presenting between June and December 2017 at the Doheny-UCLA Eye Centers. The area of GA was delineated on the en face structural OCT fundus images. For each eye, the en ...
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      Mentions: Capital Medical University Srinivas R. Sadda UCLA
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  4. About Srinivas R. Sadda

    Srinivas R. Sadda

    Srinivas R. Sadda, MD, Assistant Professor of Ophthalmology, Doheny Image Reading Center, Doheny Eye Institute, UCLA.

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  6. Quotes

    1. With CIRRUS FastTrac, I can place a highest resolution 20x B-Scan precisely on the area I am treating at each successive visit to see the fine details of the patient’s response to treatment...It’s also very helpful for removing any eye motion from the larger cube scans without disturbing my patient flow because it works so quickly. My initial experience is that FastTrac is about 30 percent faster than other tracking methods I have used.
      In Modernized new OCT platforms span full spectrum of multi-modality imaging for glaucoma and retinal disease