1. Srinivas R. Sadda

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    1. Mentioned In 105 Articles

    2. Reproducibility and Agreement Between 2 Spectral Domain Optical Coherence Tomography Devices for Anterior Chamber Angle Measurements

      Reproducibility and Agreement Between 2 Spectral Domain Optical Coherence Tomography Devices for Anterior Chamber Angle Measurements
      Purpose: To compare anterior chamber angle parameters based on the location of Schwalbe line (SL) from 2 spectral domain optical coherence tomography (SD-OCT) instruments and to measure their reproducibility. Methods: Forty-two eyes from 21 normal, healthy participants underwent imaging of the inferior irido-corneal angle with the Spectralis and Cirrus SD-OCT under tightly controlled low-light conditions. SL-angle opening distance (SL-AOD) and SL-trabecular iris space area (SL-TISA) were measured by masked, certified ...
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    3. Optical Coherence Tomography Angiography of Type 1 Neovascularization in Age-Related Macular Degenerati

      Optical Coherence Tomography Angiography of Type 1 Neovascularization in Age-Related Macular Degenerati
      Purpose To analyze type 1 neovascular membranes in age-related macular degeneration (AMD) using optical coherence tomography (OCT) angiography, to correlate morphological characteristics with imaging and clinical criteria, and to analyze structural features of type 1 neovascularization sequentially after anti-vascular endothelial growth factor (VEGF) therapy. Design Prospective interventional case series. Methods Macular OCT angiography images were acquired using the RTVue XR Avanti with AngioVue. Distinct morphological patterns and quantifiable features of ...
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    4. Optical Coherence Tomography Angiography of Type 1 Neovascularization in Age-Related Macular Degeneration

      Optical Coherence Tomography Angiography of Type 1 Neovascularization in Age-Related Macular Degeneration
      Purpose To analyze type 1 neovascular membranes in age-related macular degeneration (AMD) using optical coherence tomography (OCT) angiography, to correlate morphological characteristics with imaging and clinical criteria, and to analyze structural features of type 1 neovascularization sequentially after anti-vascular endothelial growth factor (VEGF) therapy. Design Prospective interventional case series. Methods Macular OCT angiography images were acquired using the RTVue XR Avanti with AngioVue. Distinct morphological patterns and quantifiable features of ...
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    5. Noninvasive Visualization and Analysis of the Human Parafoveal Capillary Network Using Swept Source OCT Optical Microangiography

      Noninvasive Visualization and Analysis of the Human Parafoveal Capillary Network Using Swept Source OCT Optical Microangiography
      Purpose. We characterized the foveal avascular zone (FAZ) and the parafoveal capillary network in healthy subjects using swept source OCT optical microangiography (OMAG). Methods. We acquired OMAG images of the macula of 19 eyes (13 healthy individuals) using a prototype swept source laser OCT. En face images of the retinal vasculature were generated for superficial and deep inner retinal layers (SRL/DRL) in regions of interest 250 (ROI-250) and 500 ...
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    6. Subretinal fluid in eyes with active ocular toxoplasmosis observed using spectral domain optical coherence tomography

      Subretinal fluid in eyes with active ocular toxoplasmosis observed using spectral domain optical coherence tomography
      Purpose To describe the clinical finding of subretinal fluid (SRF) in the posterior pole by spectral domain optical coherence tomography (SD-OCT) in eyes with active ocular toxoplasmosis (OT). Design Retrospective case series. Participants Thirty-eight eyes from 39 patients with active OT. Methods Eyes with active OT which underwent SD-OCT were reviewed. SRFs in the posterior pole were further analyzed. Main Outcome Measures Presence of SRF; its accompanying features, e.g ...
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    7. OCT angiography and sequential quantitative analysis of type 2 neovascularization after ranibizumab therapy

      OCT angiography and sequential quantitative analysis of type 2 neovascularization after ranibizumab therapy
      Purpose To study the precise structural aspects of a type 2 neovascular membrane in a patient with age-related macular degeneration (AMD) using optical coherence tomography (OCT) angiography and perform sequential quantitative analysis of the membrane after ranibizumab therapy. Patients and methods Split-spectrum amplitude-decorrelation (SSADA) OCT angiography macular cubes (3 3 mm) were acquired with a light source centered at 840 nm, a bandwidth of 45 nm, and an A-scan-rate of ...
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    8. Improved Repeatability of Retinal Thickness Measurements Using Line-Scan Ophthalmoscope Image-Based Retinal Tracking

      Improved Repeatability of Retinal Thickness Measurements Using Line-Scan Ophthalmoscope Image-Based Retinal Tracking
      ...Meditec and Optos. The remaining authors report no relevant financial disclosures. Address correspondence to SriniVas R. Sadda, MD, Professor of Ophthalmology, University of Southern California, Keck School of Medicine,...
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    9. A Promising Future for Optical Coherence Tomography Angiography

      A Promising Future for Optical Coherence Tomography Angiography
      This Viewpoint reports on optical coherence tomography angiography and how its use could greatly enrich our understanding of the ischemic processes affecting different layers of the retinal vasculature. Fluorescein angiography has been the gold standard imaging modality for the retinal vasculature since its groundbreaking introduction in 1961 by Alvis and Novotny and has revolutionized our ability to diagnose diseases of the retinal vasculature and to identify retinal and choroidal neovascularization ...
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    10. Comparison of Physiologic versus Pharmacologic Mydriasis on Anterior Chamber Angle Measurements Using Spectral Domain Optical Coherence Tomography

      Comparison of Physiologic versus Pharmacologic Mydriasis on Anterior Chamber Angle Measurements Using Spectral Domain Optical Coherence Tomography
      Purpose. To compare the effects of physiologic versus pharmacologic pupil dilation on anterior chamber angle (ACA) measurements obtained with spectral domain optical coherence tomography (SD-OCT). Methods. Forty eyes from 20 healthy, phakic individuals with open angles underwent anterior segment OCT imaging under 3 pupillary states: (1) pupil constricted under standard room lighting, (2) physiologic mydriasis in a darkened room, and (3) postpharmacologic mydriasis. Inferior angle Schwalbes line-angle opening distance (SL-AOD ...
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    11. Arvo Special Interest Group Meeting on Optical Coherence Tomography Angiography of the Eye

      Arvo Special Interest Group Meeting on Optical Coherence Tomography Angiography of the Eye
      The ARVO Special Interest Group meeting on "Optical Coherence Tomography Angiography of the Eye" wwill take place during ARVO 2015 meeting, in Denver Colorado. SIG Session Number: 125 Session Date/Start Time: M ay 3, 2015 from 1:30 PM to 3:00 PM Room: 2C/3C Mile High Ballroom Organizers: David Huang, Philip Rosenfeld, Moderators: Carmen Puliafito, James Fujimoto Participating in the Technology panel: David Huang, Yoshiaki Yasuno, Ruikang ...
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    12. Comparison of Retinal Thicknesses Measured Using Swept-Source and Spectral-Domain Optical Coherence Tomography Devices

      Comparison of Retinal Thicknesses Measured Using Swept-Source and Spectral-Domain Optical Coherence Tomography Devices
      To compare retinal thicknesses measured using swept-source optical coherence tomography (SS-OCT) and spectral-domain (SD) OCT devices. PATIENTS AND METHODS: In a cohort study of 76 healthy eyes and 21 eyes with high myopia, mean retinal thicknesses in ETDRS subfields were compared between OCT scans obtained from the Topcon DRI OCT-1 (Topcon, Tokyo, Japan), Spectralis OCT (Heidelberg Engineering, Heidelberg, Germany), and Cirrus HD-OCT (Carl Zeiss Meditec, Dublin, CA). RESULTS: Central retinal ...
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    13. Measurement of retinal blood flow in normal Chinese American subjects by Doppler Fourier-domain optical coherence tomography

      Measurement of retinal blood flow in normal Chinese American subjects by Doppler Fourier-domain optical coherence tomography
      PURPOSE: To measure total retinal blood flow (TRBF) in normal, healthy Chinese-Americans using semi-automated analysis of Doppler Fourier-domain optical coherence tomography (FD-OCT) scans. METHODS: Two hundred sixty-six normal, healthy Chinese-American participants (266 eyes) were enrolled from The Chinese American Eye Study (CHES). All participants underwent complete ophthalmic examination, including best-corrected visual acuity, indirect ophthalmoscopy and Doppler FD-OCT imaging, using the circumpapillary double circular scan protocol. TRBF and other vascular parameters ...
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    14. TYPE 3 NEOVASCULARIZATION: Evolution, Association With Pigment Epithelial Detachment, and Treatment Response as Revealed by Spectral Domain Optical Coherence Tomography

      TYPE 3 NEOVASCULARIZATION: Evolution, Association With Pigment Epithelial Detachment, and Treatment Response as Revealed by Spectral Domain Optical Coherence Tomography
      Purpose: To demonstrate the evolution and treatment response of Type 3 neovascularization using spectral domain optical coherence tomography. Methods: We retrospectively analyzed 40 eyes treated with intravitreal anti-vascular endothelial growth factor therapy for Type 3 neovascularization over a variable follow-up period. Results: In 17 eyes, spectral domain optical coherence tomography captured the development of Type 3 neovascularization from punctate hyperreflective foci that preceded any outer retinal defect. The more mature ...
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  2. About Srinivas R. Sadda

    Srinivas R. Sadda

    Srinivas R. Sadda, MD, Assistant Professor of Ophthalmology, Doheny Image Reading Center, Doheny Eye Institute, Keck School of Medicine of the University of Southern California.

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    1. With CIRRUS FastTrac, I can place a highest resolution 20x B-Scan precisely on the area I am treating at each successive visit to see the fine details of the patient’s response to treatment...It’s also very helpful for removing any eye motion from the larger cube scans without disturbing my patient flow because it works so quickly. My initial experience is that FastTrac is about 30 percent faster than other tracking methods I have used.
      In Modernized new OCT platforms span full spectrum of multi-modality imaging for glaucoma and retinal disease