1. Spanish National Research Council

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    1. Mentioned In 37 Articles

    2. Method for calibrating and correcting the scanning distortion of an optical coherence tomography system

      Method for calibrating and correcting the scanning distortion of an optical coherence tomography system
      Method for calibrating and correcting the scanning distortion of any optical coherence tomography system by using reference patterns and obtaining mathematical relationships between the positions of the reference points in a reference pattern and the local coordinates of said reference points, said coordinates are obtained by means of said optical coherence tomography system
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    3. OCT-based full crystalline lens shape change during accommodation in vivo

      OCT-based full crystalline lens shape change during accommodation in vivo
      The full shape of the accommodating crystalline lens was estimated using custom three-dimensional (3-D) spectral OCT and image processing algorithms. Automatic segmentation and distortion correction were used to construct 3-D models of the lens region visible through the pupil. The lens peripheral region was estimated with a trained and validated parametric model. Nineteen young eyes were measured at 0-6 D accommodative demands in 1.5 D steps. Lens volume, surface ...
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    4. Optical Coherence Tomography Based Estimates of Crystalline Lens Volume, Equatorial Diameter, and Plane Position

      Optical Coherence Tomography Based Estimates of Crystalline Lens Volume, Equatorial Diameter, and Plane Position
      Purpose : Measurement of crystalline lens geometry in vivo is critical to optimize performance of state-of-the-art cataract surgery. We used custom-developed quantitative anterior segment optical coherence tomography (OCT) and developed dedicated algorithms to estimate lens volume (VOL), equatorial diameter (DIA), and equatorial plane position (EPP). Methods : The method was validated ex vivo in 27 human donor (1971 years of age) lenses, which were imaged in three-dimensions by OCT. In vivo conditions ...
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    5. OCT-based crystalline lens topography in accommodating eyes

      OCT-based crystalline lens topography in accommodating eyes
      ustom Spectral Domain Optical Coherence Tomography (SD-OCT) provided with automatic quantification and distortion correction algorithms was used to measure anterior and posterior crystalline lens surface elevation in accommodating eyes and to evaluate relationships between anterior segment surfaces. Nine young eyes were measured at different accommodative demands. Anterior and posterior lens radii of curvature decreased at a rate of 0.78 0.18 and 0.13 0.07 mm/D, anterior ...
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    6. Observation of sound-induced corneal vibrational modes by optical coherence tomography

      Observation of sound-induced corneal vibrational modes by optical coherence tomography
      The mechanical stability of the cornea is critical for maintaining its normal shape and refractive function. Here, we report an observation of the mechanical resonance modes of the cornea excited by sound waves and detected by using phase-sensitive optical coherence tomography. The cornea in bovine eye globes exhibited three resonance modes in a frequency range of 50-400 Hz. The vibration amplitude of the fundamental mode at 80-120 Hz was ~8 ...
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    7. Numerical model of optical coherence tomographic vibrography imaging to estimate corneal biomechanical properties

      Numerical model of optical coherence tomographic vibrography imaging to estimate corneal biomechanical properties
      Most techniques measuring corneal biomechanics in vivo are biased by side factors. We demonstrate the ability of optical coherence tomographic (OCT) vibrography to determine corneal material parameters, while reducing current prevalent restrictions of other techniques (such as intraocular pressure (IOP) and thickness dependency). Modal analysis was performed in a finite-element (FE) model to study the oscillation response in isolated thin corneal flaps/eye globes and to analyse the dependency of ...
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    8. OCT 3-D surface topography of isolated human crystalline lenses

      OCT 3-D surface topography of isolated human crystalline lenses
      Quantitative 3-D Optical Coherence Tomography was used to measure surface topography of 36 isolated human lenses, and to evaluate the relationship between anterior and posterior lens surface shape and their changes with age. All lens surfaces were fitted to 6th order Zernike polynomials. Astigmatism was the predominant surface aberration in anterior and posterior lens surfaces (accounting for ~55% and ~63% of the variance respectively), followed by spherical terms, coma, trefoil ...
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    9. Madrid-MIT +Vision Consortium announces Fellowships in Translational Biomedical Imaging

      Madrid-MIT +Vision Consortium announces Fellowships in Translational Biomedical Imaging
      Madrid-MIT +Vision Consortium announces Fellowships in Translational Biomedical Imaging. Fellowships entail a training program in Madrid and Boston and development of collaborative projects between institutions in both cities. The Institute of Optics-CSIC (Madrid), as a member of the Consortium, encourages postdoctoral applications in the fields of optical ocular imaging within the frame of this program. Application deadline: April 30th 2014. Starting date: September 2th 2014. Full announcement: http://viobiolabs.wordpress ...
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    10. Eye Biometry Using Quantitative 3-D OCT

      Eye Biometry Using Quantitative 3-D OCT
      Cataracts cause the crystalline lens of the eye to progressively lose its transparency, which decreases vision. It is one of the major causes of vision loss in our aging population. Modern cataract surgery involves the replacement of the cloudy lens with an intraocullar lens (IOL). IOL designs are becomeing more sophisticated, with benefits such as aspheric surfaces, multifocality, and the capability to change position ore shape to restore accommodation.
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    11. Intraocular lens alignment from an en face optical coherence tomography image Purkinje-like method

      Intraocular lens alignment from an en face optical coherence tomography image Purkinje-like method
      Measurement of intraocular lens (IOL) alignment implanted in patients in cataract surgery is important to understand their optical performance. We present a method to estimate tilt and decentration of IOLs based on optical coherence tomography (OCT) images. En face OCT images show Purkinje-like images that correspond to the specular reflections from the corneal and IOL surfaces. Unlike in standard Purkinje-imaging, the tomographic nature of OCT allows unequivocal association of the ...
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    12. Ocular and Optical Coherence Tomography-Based Corneal Aberrometry in Keratoconic Eyes Treated by Intracorneal Ring Segments

      Ocular and Optical Coherence Tomography-Based Corneal Aberrometry in Keratoconic Eyes Treated by Intracorneal Ring Segments
      Purpose To analyze corneal and total aberrations using custom-developed anterior segment spectral optical coherence tomography (OCT) and laser ray tracing in keratoconic eyes implanted with intracorneal ring segments (ICRS). Design Evaluation of technology. Prospective study. Case series. Methods Nineteen keratoconic eyes were measured before and after ICRS surgery. Anterior and posterior corneal topographic and pachymetric maps were obtained pre- and postoperatively from 3-dimensional OCT images of the anterior segment, following ...
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    13. Static and dynamic crystalline lens accommodation evaluated using quantitative 3-D OCT

      Static and dynamic crystalline lens accommodation evaluated using quantitative 3-D OCT
      Custom high-resolution high-speed anterior segment spectral domain Optical Coherence Tomography (OCT) provided with automatic quantification and distortion correction algorithms was used to characterize three-dimensionally (3-D) the human crystalline lens in vivo in four subjects, for accommodative demands between 0 to 6 D in 1 D steps. Anterior and posterior lens radii of curvature decreased with accommodative demand at rates of 0.73 and 0.20 mm/D, resulting in an ...
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    14. Three-Dimensional Evaluation of Accommodating Intraocular Lens Shift and Alignment In Vivo

      Three-Dimensional Evaluation of Accommodating Intraocular Lens Shift and Alignment In Vivo
      Objective To quantify 3-dimensionally the anterior segment geometry, biometry, and lens position and alignment in patients before and after implantation of the Crystalens-AO (Bausch Lomb, Rochester, NY) accommodating intraocular lens (A-IOL). Design Prospective, observational study. Participants Ten patients (20 eyes) with cataract before and after implantation of the Crystalens-AO A-IOL. Methods Custom full anterior segment 3-dimensional (3-D) spectral optical coherence tomography (OCT) provided with quantification tools was used to image ...
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  2. About Spanish National Research Council

    Spanish National Research Council

    Spanish National Research Council (Consejo Superior de Investigaciones Cientificas - CSIC) is the largest public institution dedicated to research in Spain and the third largest in Europe. Belonging to the Spanish Ministry of Science and Innovation through the Secretary of State for Research, its main objective is to develop and promote research that will help bring about scientific and technological progress, and it is prepared to collaborate with Spanish and foreign entities in order to achieve this aim. Also see Visual Optics and Biophotonics Lab at CSIC.