1. South China Normal University

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    1. Mentioned In 45 Articles

    2. The effects of electrical pulses-mediated gold and silver nanoparticles on the optical properties of ex vivo human femoral head tissue with optical coherence tomography

      The effects of electrical pulses-mediated gold and silver nanoparticles on the optical properties of ex vivo human femoral head tissue with optical coherence tomography
      This study aims to monitor and assess the penetration and accumulation of gold nanoparticles (Au NPs) or silver nanoparticles (Ag NPs) (average particle size 40 nm) and the penetration of the Au NPs or Ag NPs assisted by electrical impulses (EP) in human normal femoral head (NFH) and pathological femoral head (PFH) tissues. The results show that optical coherence tomography images can easily distinguish NFH from PFH tissues. The control ...
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    3. Optical coherence hyperspectral microscopy with a single supercontinuum light source

      Optical coherence hyperspectral microscopy with a single supercontinuum light source
      In the paper, we have developed an optical coherence hyperspectral microscopy with a single supercontinuum light source. The microscopy consists of optical coherence tomography (OCT) and hyperspectral imaging (HSI), which can visualize the structural and functional characteristics of biological tissues. The 500-700 nm band is selected for HSI and OCT imaging, where HSI enables imaging of oxygen saturation and hemoglobin (Hb) content, while OCT acquires structural characteristics to assess the ...
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    4. Retinal cross‐section motion correction in three‐dimensional retinal optical coherence tomography

      Retinal cross‐section motion correction in three‐dimensional retinal optical coherence tomography
      Motion correction is an important issue in ophthalmic optical coherence tomography (OCT), and can improve the ability of datasets to reflect the physiological structures of tissues and make visualization and subsequent analysis easier. In this study, we present a novel method to correct the cross-sectional motion artifacts in retinal OCT volumes. Motion along the x-direction (fast-scan direction) is corrected through the normalized cross-correlation algorithm, while axial motion compensation is performed ...
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    5. Redox responsive nanoparticle encapsulating black phosphorus quantum dots for cancer theranostics

      Redox responsive nanoparticle encapsulating black phosphorus quantum dots for cancer theranostics
      Effective cancer treatment puts high demands for cancer theranostics. For cancer diagnostics, optical coherence tomography (OCT) technology (including photothermal optical coherence tomography (PT-OCT)) has been widely investigated since it induces changes in optical phase transitions in tissue through environmental changes (such as temperature change for PT-OCT). In this report, redox responsive nanoparticle encapsulating black phosphorus quantum dots was developed as a robust PT-OCT agent. Briefly, black phosphorus quantum dots (BPQDs ...
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    6. Towards quantitative assessment of burn based on photoacoustic and optical coherence tomography

      Towards quantitative assessment of burn based on photoacoustic and optical coherence tomography
      Accurate and timely assessment of the severity of burn is essential for the treatment of burns. Currently, although most first‐degree and third‐degree burns are easily diagnosed through visual inspection or auxiliary diagnostic methods, the second‐degree burn is still difficult to distinguish due to the ambiguity boundaries of second‐degree with first‐degree and third‐degree burns. In this study, we proposed a non‐invasive technique by combing ...
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    7. Multi-parameter characterization of atherosclerotic plaques based on optical coherence tomography, photoacoustic and viscoelasticity imaging

      Multi-parameter characterization of atherosclerotic plaques based on optical coherence tomography, photoacoustic and viscoelasticity imaging
      Detection of atherosclerotic plaque vulnerability is the critical step in prevention of acute coronary events. Fibrous cap thickness, lipid core size, and inflammation extent are three key parameters for assessing plaque vulnerability. Here, we report on multimodality imaging of mice aortic plaques using a system that integrates optical coherence tomography (OCT), photoacoustic imaging (PAI), and photoacoustic viscoelasticity imaging (PAVEI). The thickness of fibrous cap is accurately evaluated by OCT, and ...
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    8. Optical Biopsy of Melanoma and Basal Cell Carcinoma Progression by Noncontact Photoacoustic and Optical Coherence Tomography: In vivo Multi-parametric Characterizing Tumor Microenvironment

      Optical Biopsy of Melanoma and Basal Cell Carcinoma Progression by Noncontact Photoacoustic and Optical Coherence Tomography: In vivo Multi-parametric Characterizing Tumor Microenvironment
      Measuring the structural and functional status of tumor microenvironment for malignant melanoma (MM) and basal cell carcinoma (BCC) is of profound significance in understanding dermatological condition for biopsy. However, conventional optical imaging techniques are limited to visualize superficial skin features and parameter information is deficient to depict pathophysiology correlations of skin diseases. Here, we demonstrate a preclinical device, all-optically integrated photoacoustic and optical coherence tomography (AOPA/OCT), that, for the ...
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    9. Co-impulse multispectral photoacoustic microscopy and optical coherence tomography system using a single supercontinuum laser

      Co-impulse multispectral photoacoustic microscopy and optical coherence tomography system using a single supercontinuum laser
      A combination of multispectral photoacoustic microscopy (PAM) and optical coherence tomography (OCT) by a single light source was previously realized discretely; however, this is unfavorable for visualizing vital physiological and pathological activities in vivo . Here, a co-impulse dual-mode imaging system that simultaneously enables multispectral PAM and OCT using a megahertz supercontinuum pulse laser in vivo is presented. The 500600 nm band is used for functional PAM imaging, which can flexibly ...
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    10. Cross-correlation photothermal optical coherence tomography with high effective resolution

      Cross-correlation photothermal optical coherence tomography with high effective resolution
      We developed a cross-correlation photothermal optical coherence tomography (CC-PTOCT) system for photothermal imaging with high lateral and axial resolution. The CC-PTOCT system consists of a phase-sensitive OCT system, a modulated pumping laser, and a digital cross-correlator. The pumping laser was used to induce the photothermal effect in the sample, causing a slight phase modulation of the OCT signals. A spatial phase differentiation method was employed to reduce phase accumulation. The ...
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    11. Optical biopsy approach to basal cell carcinoma and melanoma based on all-optically integrated photoacoustic and optical coherence tomography

      Optical biopsy approach to basal cell carcinoma and melanoma based on all-optically integrated photoacoustic and optical coherence tomography
      Basal cell carcinoma (BCC) and melanoma (MM), with the highest morbidity and mortality, respectively, are considered as two skin cancers of concern in dermatology. Histological studies have demonstrated that vascular patterns and collagenous stroma serve as key parameters for BCC and MM classification. In this Letter, we sought to identify BCC and MM based on the dual parameters of vascular patterns and scattering structures provided by all-optically integrated photoacoustic and ...
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    12. Noninvasive monitoring of blood glucose concentration in diabetic patients with optical coherence tomography

      Noninvasive monitoring of blood glucose concentration in diabetic patients with optical coherence tomography
      Optical coherence tomography (OCT) has been used to noninvasively monitor the blood glucose concentration (BGC) in healthy subjects with good accuracy and acceptable specificity. Based on this, the paper further considered the possibility of OCT in noninvasive monitoring BGC in diabetic patients. The OCT signal slope (OCTSS) changed with variation of BGC. The correlation coefficient R between BGC and OCTSS in diabetic patients was 0.91; while the correlation coefficient ...
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    13. Simultaneous imaging of atherosclerotic plaque composition and structure with dual-mode photoacoustic and optical coherence tomography

      Simultaneous imaging of atherosclerotic plaque composition and structure with dual-mode photoacoustic and optical coherence tomography
      The composition of plaque is a major determinant of coronary-related clinical syndromes. By combining photoacoustic tomography (PAT) and optical coherence tomography (OCT), the optical absorption and scattering properties of vascular plaque can be revealed and subsequently used to distinguish the plaque composition and structure. The feasibility and capacity of the dual-mode PAT-OCT technique for resolving vascular plaque was first testified by plaque composition mimicking experiment. PAT obtained lipid information due ...
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    14. A Correlation Study between Two Adjacent Same-Meridian Acupoints after Laser-Needle Acupuncture with Optical Coherence Tomography and Diffuse Reflectance Spectra

      A Correlation Study between Two Adjacent Same-Meridian Acupoints after Laser-Needle Acupuncture with Optical Coherence Tomography and Diffuse Reflectance Spectra
      This study is to investigate the correlations among Sanjian (LI3), Hegu (LI4), and Yangxi (LI5) acupoints and their corresponding nonacupoints on the Yangming Large Intestine Meridian of Hand before and after laser irradiation using optical coherence tomography (OCT) and diffuse reflectance spectra. The experiment was conducted on 10 healthy people. A 658nm laser with 50mW output power was used for irradiating LI4, LI5 acupoints and their corresponding nonacupoints. As to ...
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    15. In Vivo Detection of the Effect of Electroacupuncture on “Zusanli” Acupoint in Rats with Adjuvant-Induced Arthritis through Optical Coherence Tomography

      In Vivo Detection of the Effect of Electroacupuncture on “Zusanli” Acupoint in Rats with Adjuvant-Induced Arthritis through Optical Coherence Tomography
      This study aimed to investigate the effect of electroacupuncture (EA) treatment through optical coherence tomography (OCT) in vivo on rats with adjuvant-induced arthritis. OCT images were obtained from the ankle of the right hind paws of the rats in control, model, and EA groups before modelling and 1 day, 8 days, 15 days, 22 days, and 29 days after modelling. Results demonstrated that the OCT signal of the ankle of ...
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    16. All-optically integrated multimodality imaging system: combined photoacoustic microscopy, optical coherence tomography, and fluorescence imaging

      All-optically integrated multimodality imaging system: combined photoacoustic microscopy, optical coherence tomography, and fluorescence imaging
      We have developed a multimodality imaging system by optically integrating all-optical photoacoustic microscopy (AOPAM), optical coherence tomography (OCT) and fluorescence microscopy (FLM) to provide complementary information including optical absorption, optical back-scattering and fluorescence contrast of biological tissue. By sharing the same low-coherence Michelson interferometer, AOPAM and OCT could be organically optically combined to obtain the absorption and scattering information of the biological tissues. Also, owing to using the same laser ...
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    17. 1-15 of 45 1 2 3 »
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  2. About South China Normal University

    South China Normal University

    South China Normal University is an institution of higher learning with a long history and a rich legacy. Situated in Guangzhou, an open metropolis in South China, the University is imbued with Lingnan’s pioneering and pragmatic spirit. It has a tradition of elegant simplicity and a favourable learning atmosphere. In the past seventy years or so, the University has all along preserved its distinguishing characteristics, mainly concentrating on teacher-education and training, and has dedicated itself to training qualified teachers and professionals of other kind, viz., outstanding personnel of moral integrity, high thinking, inventive ability, with a sense of responsibility.