1. Soochow University

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    1. Mentioned In 49 Articles

    2. Algorithm for Detection and Quantification of Hyperreflective Dots on Optical Coherence Tomography in Diabetic Macular Edema

      Algorithm for Detection and Quantification of Hyperreflective Dots on Optical Coherence Tomography in Diabetic Macular Edema
      Purpose: To develop an algorithm to detect and quantify hyperreflective dots (HRDs) on optical coherence tomography (OCT) in patients with diabetic macular edema (DME). Materials and Methods: Twenty OCTs (each OCT contains 128 b scans) from 20 patients diagnosed with DME were included in this study. Two types of HRDs, hard exudates and small HRDs (hypothesized to be activated microglia), were identified and labeled independently by two raters. An algorithm ...
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    3. Development of a handheld compression optical coherence elastography probe with a disposable stress sensor

      Development of a handheld compression optical coherence elastography probe with a disposable stress sensor
      Optical coherence elastography (OCE) is a functional extension of optical coherence tomography (OCT). OCE measures a samples deformation under force stimuli. Compression is often used to generate the force stimuli in OCE. In this Letter, we report the development of a handheld quantitative compression OCE probe with a novel stress senor, dedicated to measuring the force. The stress sensor consists of a circular glass window and a metal ring which ...
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    4. Inspection of Intraocular Lens with Dual-side View Optical Coherence Tomography

      Inspection of Intraocular Lens with Dual-side View Optical Coherence Tomography
      Intraocular lens (IOL) is widely used for cataract treatment. Its optical properties are crucial to obtain a good treatment efficacy and thus need to be evaluated and controlled. In this study, we propose a novel method based on optical coherence tomography (OCT) for noncontact and accurate in vitro measurement of thickness, refractive index and dioptric power of IOL implants. The OCT setup is specially designed to create two sampling optics ...
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    5. Changes in circumpapillary retinal vessel density after acute primary angle closure episode via OCT angiography

      Changes in circumpapillary retinal vessel density after acute primary angle closure episode via OCT angiography
      Purpose: To investigate the changes and evaluate the diagnosis value of circumpapillary vessel density (VD) in cases of acute primary angle closure (APAC). Design: Case-control study. Methods: APAC patients with a history of unilateral acute attack were enrolled. The eyes with acute episode constituted the case group while the contralateral eyes without attack consisted of the control group. Ophthalmic examinations including slit-lamp examination, best-corrected visual acuity, intraocular pressure and visual ...
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    6. Speckle Noise Reduction for OCT Images based on Image Style Transfer and Conditional GAN

      Speckle Noise Reduction for OCT Images based on Image Style Transfer and Conditional GAN
      Raw optical coherence tomography (OCT) images typically are of low quality because speckle noise blurs retinal structures, severely compromising visual quality and degrading performances of subsequent image analysis tasks. In our previous study, we have developed a Conditional Generative Adversarial Network (cGAN) for speckle noise removal in OCT images collected by several commercial OCT scanners, which we collectively refer to as scanner T. In this paper, we improve the cGAN ...
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    7. A Joint Model for Macular Edema Analysis in Optical Coherence Tomography Images Based on Image Enhancement and Segmentation

      A Joint Model for Macular Edema Analysis in Optical Coherence Tomography Images Based on Image Enhancement and Segmentation
      Optical coherence tomography (OCT) provides the visualization of macular edema which can assist ophthalmologists in the diagnosis of ocular diseases. Macular edema is a major cause of vision loss in patients with retinal vein occlusion (RVO). However, manual delineation of macular edema is a laborious and time-consuming task. This study proposes a joint model for automatic delineation of macular edema in OCT images. This model consists of two steps: image ...
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    8. Axial and horizontal registration guided speckle suppression in single-line HD mode for retinal optical coherence tomography images

      Axial and horizontal registration guided speckle suppression in single-line HD mode for retinal optical coherence tomography images
      We propose an image registration method to suppress the speckle noise in retinal optical coherence tomography(OCT) adapted to single-line HD mode hardware implementation. In single-line HD mode, multiple cross-section images at the same straight scan line are obtained repeatedly and rapidly for averaging the speckle noise. Not like static objects, cross-section retinal images are often blurred by direct averaging due to unintentional eye/head motions in axial and horizontal ...
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    9. Semi-Supervised Capsule cGAN for Speckle Noise Reduction in Retinal OCT Images

      Semi-Supervised Capsule cGAN for Speckle Noise Reduction in Retinal OCT Images
      Speckle noise is the main cause of poor optical coherence tomography (OCT) image quality. Convolutional neural networks (CNNs) have shown remarkable performances for speckle noise reduction. However, speckle noise denoising still meets great challenges because the deep learning-based methods need a large amount of labeled data whose acquisition is time-consuming or expensive. Besides, many CNNs-based methods design complex structure based networks with lots of parameters to improve the denoising performance ...
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    10. Analysis of macular microvasculature and thickness after ICL implantation in patients with myopia using optical coherence tomography

      Analysis of macular microvasculature and thickness after ICL implantation in patients with myopia using optical coherence tomography
      AIM To investigate changes in macular vessels and thickness in myopic eyes after intraocular collamer lens (ICL) implantation using quantitative optical coherence tomography angiography (OCTA). METHODS This retrospective included 73 myopic eyes of 73 patients (average age, 27.536.16y) who underwent ICL implantation (28 eyes were Toric ICL). Axial length (AL), uncorrected visual acuity (UCVA), refractive dioptre (RD), intraocular pressure (IOP) and OCTA were measured and compared with before ...
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    11. Quantitative Analysis of Macular Retina Using Light Reflection Indices Derived from SD-OCT for Pituitary Adenoma

      Quantitative Analysis of Macular Retina Using Light Reflection Indices Derived from SD-OCT for Pituitary Adenoma
      Purpose: To quantitatively investigate the macular retinal light reflection characteristic using optical property indices derived from spectral-domain optical coherence tomography (SD-OCT) scans with depth attenuation compensation for pituitary adenoma. Methods: This study included 38 patients (mean age 44.66 13.77 years old) with diagnosis of pituitary adenoma and 43 age-matched controls. All SD-OCT scans were light attenuation compensated by a depth-resolved model. Attenuation coefficient, the corrected intensity, and the ...
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    12. AGE challenge: Angle Closure Glaucoma Evaluation in Anterior Segment Optical Coherence Tomography

      AGE challenge: Angle Closure Glaucoma Evaluation in Anterior Segment Optical Coherence Tomography
      Angle closure glaucoma (ACG) is a more aggressive disease than open-angle glaucoma, where the abnormal anatomical structures of the anterior chamber angle (ACA) may cause an elevated intraocular pressure and gradually lead to glaucomatous optic neuropathy and eventually to visual impairment and blindness. Anterior Segment Optical Coherence Tomography (AS-OCT) imaging provides a fast and contactless way to discriminate angle closure from open angle. Although many medical image analysis algorithms have ...
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    13. Low Tensor Train- and Low Multilinear Rank Approximationsfor De-speckling and Compression of 3D Optical Coherence Tomography Images

      Low Tensor Train- and Low Multilinear Rank Approximationsfor De-speckling and Compression of 3D Optical Coherence Tomography Images
      This paper proposes low tensor-train (TT) rank and low multilinear (ML) rank approximations for de-speckling and compression of 3D optical coherence tomography (OCT) images for a given compression ratio (CR). To this end, we derive the alternating direction method of multipliers based algorithms for the related problems constrained with the low TT- and low ML rank. Rank constraints are implemented through the Schatten-p (Sp) norm, p e {0, 1/2 ...
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    14. Characterization of the Three Distinct Retinal Capillary Plexuses Using Optical Coherence Tomography Angiography in Myopic Eyes

      Characterization of the Three Distinct Retinal Capillary Plexuses Using Optical Coherence Tomography Angiography in Myopic Eyes
      Purpose : To segment and quantify three distinct retinal capillary plexuses using optical coherence tomography angiography (OCTA) in myopic eyes. Methods : We analyzed 96 eyes from 62 subjects with myopia (27.76 7.05 years of age) and evaluated 30 normal eyes from 15 subjects (28.33 3.13 years of age) for controls. En face OCTA images generated by AngioPlex (Carl Zeiss; Oberkochen, Germany) were manually segmented by the progressive ...
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    15. AGE Challenge: Angle Closure Glaucoma Evaluation in Anterior Segment Optical Coherence Tomography

      AGE Challenge: Angle Closure Glaucoma Evaluation in Anterior Segment Optical Coherence Tomography
      Angle closure glaucoma (ACG) is a more aggressive disease than open-angle glaucoma, where the abnormal anatomical structures of the anterior chamber angle (ACA) may cause an elevated intraocular pressure and gradually leads to glaucomatous optic neuropathy and eventually to visual impairment and blindness. Anterior Segment Optical Coherence Tomography (AS-OCT) imaging provides a fast and contactless way to discriminate angle closure from open angle. Although many medical image analysis algorithms have ...
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    16. Dual-side view optical coherence tomography for thickness measurement on opaque materials

      Dual-side view optical coherence tomography for thickness measurement on opaque materials
      Optical coherence tomography (OCT), as an optical interferometric imaging technique, has found wide applications in various fields. In principle, OCT is well suited for imaging layered structures, and thus, one of the typical applications is thickness measurement. However, due to the limited imaging depth resulting from light attenuation, thickness measurement by OCT is limited to non-opaque materials. In this study, we developed a novel (to the best of our knowledge ...
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  2. About Soochow University

    Soochow University

    Soochow University is a university in Suzhou , Jiangsu , China. The School of Humanities, School of Textile and Clothing Engineering, School of Chemistry, Chemical Engineering and Materials Science, and School of Medicine are the university's most visibly distinguished schools.