Articles that mention Shuichi Makita -Optical Coherence Tomography News

Shuichi Makita

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1. Mentioned In 97 Articles
2. Optical coherence tomography-based tissue dynamics imaging for longitudinal and drug response evaluation of tumor spheroids
  
  Explore OSA | OSA Publishing Dec 9 2020
  
  We present optical coherence tomography (OCT)-based tissue dynamics imaging method to visualize and quantify tissue dynamics such as subcellular motion based on statistical analysis of rapid-time-sequence OCT signals at the same location. The analyses include logarithmic intensity variance (LIV) method and two types of OCT correlation decay speed analysis (OCDS). LIV is sensitive to the magnitude of the signal fluctuations, while OCDSs including early- and late-OCDS (OCDS e and ...
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  Mentions: Shuichi Makita Yoshiaki Yasuno University of Tsukuba
3. Quantitative multi-contrast in vivo mouse imaging with polarization diversity optical coherence tomography and angiography
  
  Explore OSA | OSA Publishing Nov 11 2020 Ophthalmology
  
  Retinal microvasculature and the retinal pigment epithelium (RPE) play vital roles in maintaining the health and metabolic activity of the eye. Visualization of these retina structures is essential for pre-clinical studies of vision-robbing diseases, such as age-related macular degeneration (AMD). We have developed a quantitative multi-contrast polarization diversity OCT and angiography (QMC-PD-OCTA) system for imaging and visualizing pigment in the RPE using degree of polarization uniformity (DOPU), along with flow ...
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  Mentions: Shuichi Makita Yoshiaki Yasuno University of British Columbia
4. Depth‐resolved investigation of multiple optical properties and wrinkle morphology in eye‐corner areas with multi‐contrast Jones matrix optical coherence tomography
  
  Explore Wiley Online Library Oct 30 2020 Dermatology
  
  Background Multi‐contrast Jones matrix optical coherence tomography (JM‐OCT) can provide quantitative depth‐resolved local optical properties by improving the measurement algorithm. Materials and methods We examined the relationship between depth‐resolved local optical properties of eye‐corner skin measured by JM‐OCT and corresponding wrinkle morphology of aged women (n = 21; age range, 71.7 1.7 years). Wrinkle morphology was analyzed by measuring the surface topography of ...
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  Mentions: Shuichi Makita Yoshiaki Yasuno University of Tsukuba
5. Bulk-phase-error correction for phase-sensitive signal processing of optical coherence tomography
  
  Explore OSA | OSA Publishing Oct 4 2020
  
  We present a numerical phase stabilization method for phase-sensitive signal processing of optical coherence tomography (OCT). This method removes the bulk phase error caused by the axial bulk motion of the sample and the environmental perturbation during volumetric acquisition. In this method, the partial derivatives of the phase error are computed along both fast and slow scanning directions, so that the vectorial gradient field of the phase error is given ...
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  Mentions: Shuichi Makita Yoshiaki Yasuno University of Tsukuba
6. Polarization-sensitive optical coherence elastography
  
  Explore OSA | OSA Publishing Sep 22 2019
  
  Polarization-sensitive optical coherence elastography (PS-OCE) is developed for improved tissue discrimination. It integrates Jones matrix-based PS-optical coherence tomography (PS-OCT) with compression OCE. The method simultaneously measures the OCT intensity, attenuation coefficient, birefringence, and microstructural deformation (MSD) induced by tissue compression. Ex vivo porcine aorta and esophagus tissues were investigated by PS-OCE and histological imaging. The tissue properties measured by PS-OCE are shown as cross-sectional images and a three-dimensional (3-D) depth-trajectory ...
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  Mentions: Shuichi Makita Yoshiaki Yasuno University of Tsukuba
7. Evaluation of Retinal Pigment Epithelium Layer Change in Vogt-Koyanagi-Harada Disease With Multicontrast Optical Coherence Tomography
  
  Explore IOVS Journal Aug 6 2019 Ophthalmology
  
  Purpose : Clinical evaluation of retinal pigment epithelium (RPE) change is important for the therapeutic management of chronic Vogt-Koyanagi-Harada (VKH) disease. We evaluated long-term change in the RPE layer in VKH disease, using near-infrared (NIR; 817 nm) images and autofluorescence images at 488 nm (short-wavelength [SW]-AF) and 785 nm (NIR-AF), and compared those images with images from multicontrast optical coherence tomography (MC-OCT). MC-OCT is capable of simultaneous measurement of OCT ...
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  Mentions: Shuichi Makita Yoshiaki Yasuno Masahiro Miura
8. Multi-scale and -contrast sensorless adaptive optics optical coherence tomography
  
  Explore Home May 28 2019 Ophthalmology
  
  Background: The roles of the retinal microvasculature and the retinal pigment epithelium (RPE) in maintaining the health and metabolic activity of the retina lend great clinical value to their high-resolution visualization. Methods: By integrating polarization diversity detection (PDD) into multi-scale and -contrast sensorless adaptive optics optical coherence tomography (MSC-SAO-OCT), we have developed a novel multi-contrast SAO OCT system for imaging pigment in the RPE as well as flow in the ...
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  Mentions: Shuichi Makita Yoshiaki Yasuno Oregon Health & Science University
9. Clinical prototype of pigment and flow imaging optical coherence tomography for posterior eye investigation
  
  Explore OSA | OSA Publishing Aug 25 2018
  
  Measurements of the randomness of polarization (RP) obtained using polarization-sensitive optical coherence tomography (PS-OCT) are applied in several applications, and RP is attractive for posterior eye imaging. The addition of RP without retardation requires a minimal extension to standard OCT; therefore, we developed a prototype OCT system with a simplified scheme for RP measurement. A compact polarization-diversity receiver module is the only required hardware extension to a standard OCT system ...
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  Mentions: Shuichi Makita Yoshiaki Yasuno University of Tsukuba
10. Machine-learning based segmentation of the optic nerve head using multi-contrast Jones matrix optical coherence tomography with semi-automatic training dataset generation
  
  Explore OSA | OSA Publishing Jun 26 2018
  
  A pixel-by-pixel tissue classification framework using multiple contrasts obtained by Jones matrix optical coherence tomography (JM-OCT) is demonstrated. The JM-OCT is an extension of OCT that provides OCT, OCT angiography, birefringence tomography, degree-of-polarization uniformity tomography, and attenuation coefficient tomography, simultaneously. The classification framework consists of feature engineering, k -means clustering that generates a training dataset, training of a tissue classifier using the generated training dataset, and tissue classification by the ...
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  Mentions: Shuichi Makita Yoshiaki Yasuno University of Tsukuba
11. Pixel-wise segmentation of severely pathologic retinal pigment epithelium and choroidal stroma using multi-contrast Jones matrix optical coherence tomography
  
  Explore OSA | OSA Publishing Jun 12 2018 Ophthalmology
  
  Tissue segmentation of retinal optical coherence tomography (OCT) is widely used in ophthalmic diagnosis. However, its performance in severe pathologic cases is still insufficient. We propose a pixel-wise segmentation method that uses the multi-contrast measurement capability of Jones matrix OCT (JM-OCT). This method is applicable to both normal and pathologic retinal pigment epithelium (RPE) and choroidal stroma. In this method, features, which are sensitive to specific tissues of interest, are ...
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  Mentions: Shuichi Makita Yoshiaki Yasuno Masahiro Miura
12. Simultaneous tissue birefringence and deformation measurement by polarization sensitive optical coherence elastography with active compression
  
  Explore SPIE Digital Library Apr 16 2018
  
  Polarization sensitive optical coherence tomography (PS-OCT) measures tissue birefringence, while optical coherence elastography (OCE) reveals the mechanical property of the tissue. Since both birefringence and mechanical properties are associated with tissue microstructures such as collagen, simultaneous PS-OCT and OCE measurement will provide useful insight for the tissue microstructures. In this paper, we present a combined PS-OCT and OCE technique. The PS-OCT is based on Jones matrix OCT theory. It measures ...
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  Mentions: Shuichi Makita Yoshiaki Yasuno University of Tsukuba
13. Objective evaluation of choroidal melanin contents with polarization-sensitive optical coherence tomography
  
  Explore SPIE Digital Library Feb 27 2018 Ophthalmology
  
  We non-invasively evaluated choroidal melanin contents in human eyes with PS-OCT. We calculated the percentage area of low DOPU in the choroidal interstitial stroma for Vogt-Koyanagi- Harada disease with sunset glow fundus, without sunset glow fundus, control group and tessellated fundus with high myopia. The mean percentage area of low DOPU in the sunset group was significantly lower than the other groups. PS-OCT provides an in vivo objective evaluation of ...
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  Mentions: Shuichi Makita Yoshiaki Yasuno Masahiro Miura
14. Eye-motion-corrected optical coherence tomography angiography using Lissajous scanning
  
  Explore OSA | OSA Publishing Feb 17 2018
  
  To correct eye motion artifacts in en face optical coherence tomography angiography (OCT-A) images, a Lissajous scanning method with subsequent software-based motion correction is proposed. The standard Lissajous scanning pattern is modified to be compatible with OCT-A and a corresponding motion correction algorithm is designed. The effectiveness of our method was demonstrated by comparing en face OCT-A images with and without motion correction. The method was further validated by comparing ...
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  Mentions: Shuichi Makita Yoshiaki Yasuno University of Tsukuba
15. Generation and optimization of superpixels as image processing kernels for Jones matrix optical coherence tomography
  
  Explore OSA | OSA Publishing Sep 12 2017
  
  Jones matrix-based polarization sensitive optical coherence tomography (JM-OCT) simultaneously measures optical intensity, birefringence, degree of polarization uniformity, and OCT angiography. The statistics of the optical features in a local region, such as the local mean of the OCT intensity, are frequently used for image processing and the quantitative analysis of JM-OCT. Conventionally, local statistics have been computed with fixed-size rectangular kernels. However, this results in a trade-off between image sharpness ...
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  Mentions: Shuichi Makita Yoshiaki Yasuno University of Tsukuba
16. Noise-bias and polarization-artifact corrected optical coherence tomography by maximum a-posteriori intensity estimation
  
  Explore OSA | OSA Publishing Mar 4 2017 Ophthalmology
  
  We propose using maximum a-posteriori (MAP) estimation to improve the image signal-to-noise ratio (SNR) in polarization diversity (PD) optical coherence tomography. PD-detection removes polarization artifacts, which are common when imaging highly birefringent tissue or when using a flexible fiber catheter. However, dividing the probe power to two polarization detection channels inevitably reduces the SNR. Applying MAP estimation to PD-OCT allows for the removal of polarization artifacts while maintaining and improving ...
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  Mentions: Shuichi Makita Yoshiaki Yasuno Masahiro Miura
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