1. Sharon F. Freedman

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    1. Mentioned In 39 Articles

    2. Overhead Mounted Optical Coherence Tomography in Childhood Glaucoma Evaluation

      Overhead Mounted Optical Coherence Tomography in Childhood Glaucoma Evaluation
      Prcis: Overhead mounted spectral-domain optical coherence tomography enables high quality imaging of the optic nerve and macula in childhood glaucoma and is particularly useful when standard tabletop optical coherence tomography has failed or is not possible. Purpose: Tabletop optical coherence tomography, integral to adult glaucoma management, can be limited in childhood glaucoma patients due to young age, poor cooperation, and/or technical challenges. To address these imaging difficulties, we determined ...
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    3. Reversal of Cupping in an Infant, Shown by Optical Coherence Tomography

      Reversal of Cupping in an Infant, Shown by Optical Coherence Tomography
      A 10-month-old white male infant with primary congenital glaucoma underwent successful goniotomy in the right eye, lowering intraocular pressure from 34 mm Hg to 11 mm Hg and decreasing axial length from 23.4 mm to 22.8 mm. We used optical coherence tomography (HRA+OCT Spectralis with Flex module [Heidelberg Engineering]) to image the optic nerve preoperatively and at 1 month postoperatively. The cup-disc ratio decreased from 0.6 ...
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    4. Optical Coherence Tomography normative peripapillary retinal nerve fiber layer and macular data in children ages 0-5 years

      Optical Coherence Tomography normative peripapillary retinal nerve fiber layer and macular data in children ages 0-5 years
      Purpose To determine reference values for the peripapillary retinal nerve fiber layer (pRNFL) and macula in children ages 0-5 years. Design Prospective cross-sectional study Setting Single large academic pediatric ophthalmology practice Study Population Healthy, full-term children ages 0 to 6 years presenting for surgery under general anesthesia were prospectively recruited for participation. Excluded were children with systemic neurologic disease, optic nerve or retinal disease (even if unilateral), or any bilateral ...
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    5. Handheld Optical Coherence Tomography Normative Inner Retinal Layer Measurements for Children <5 Years

      Handheld Optical Coherence Tomography Normative Inner Retinal Layer Measurements for Children <5 Years
      Purpose Measurements of the ganglion cell complex (GCC), comprising the retinal nerve fiber (RNFL), ganglion cell, and inner plexiform layers, can be correlated with vision loss caused by optic nerve disease. Handheld optical coherence tomography (HH-OCT) can be used with sedation in children not amenable to traditional imaging. Purpose: to report GCC and RNFL measurements in normal children using HH-OCT. Design Prospective observational study of normal children 5-years of age ...
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    6. Handheld Optical Coherence Tomography Normative Inner Retinal Layer Measurements for Children

      Handheld Optical Coherence Tomography Normative Inner Retinal Layer Measurements for Children
      Purpose Measurements of the ganglion cell complex (GCC), comprising the retinal nerve fiber (RNFL), ganglion cell, and inner plexiform layers, can be correlated with vision loss caused by optic nerve disease. Handheld optical coherence tomography (HH-OCT) can be used with sedation in children not amenable to traditional imaging. Purpose: to report GCC and RNFL measurements in normal children using HH-OCT. Design Prospective observational study of normal children 5-years of age ...
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    7. Hyperreflective Vitreous Opacities on Optical Coherence Tomography in a Patient With Bilateral Retinoblastoma

      Hyperreflective Vitreous Opacities on Optical Coherence Tomography in a Patient With Bilateral Retinoblastoma
      An investigational, portable spectral-domain optical coherence tomography (SD-OCT) unit revealed small hyperreflective opacities in both eyes of a patient with bilateral retinoblastoma. There was no evidence of vitreous seeding on ophthalmoscopy of either eye. Although the opacities may initially raise concern for potential vitreous seeding, this report suggests alternate potential etiologies for such opacities, which were also seen on imaging of a cohort of normal eyes in pediatric patients.
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    8. Imaging infant retinal vasculature with optical coherence tomography angiography

      Imaging infant retinal vasculature with optical coherence tomography angiography
      Study of infant retinal vascular development has been limited to histopathological reports. We report herein depth-resolved visualization of full-term infant parafoveal microvasculature and their similarity to that of young children using a portable optical coherence tomography angiography system.
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    9. Four-dimensional Microscope-Integrated Optical Coherence Tomography to Visualize Suture Depth in Strabismus Surgery

      Four-dimensional Microscope-Integrated Optical Coherence Tomography to Visualize Suture Depth in Strabismus Surgery
      The authors report the use of swept-source microscope-integrated optical coherence tomography (SS-MIOCT), capable of live four-dimensional (three-dimensional across time) intraoperative imaging, to directly visualize suture depth during lateral rectus resection. Key surgical steps visualized in this report included needle depth during partial and full-thickness muscle passes along with scleral passes.
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    10. Use of Optical Coherence Tomography in the Eyes of Children

      Use of Optical Coherence Tomography in the Eyes of Children
      OCT has found its niche within virtually all ophthalmic subspecialties, be it glaucoma, retina/vitreous, or anterior segment. OCTs role in the diagnosis, management, and treatment of pediatric eye disease continues to evolve. Monumental gains have been made in our understanding of various physiologic principles and pathological processes as a result of this relatively new technology. While not intended to be an exhaustive catalogue of the opportunities afforded by OCT ...
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    11. Spectral domain optical coherence tomography (SD-OCT) Imaging of the Vascular-Avascular junction in the nursery in infants with retinopathy of prematurity

      Spectral domain optical coherence tomography (SD-OCT) Imaging of the Vascular-Avascular junction in the nursery in infants with retinopathy of prematurity
      Since the publication of Foos, there has been little additional microanatomic data on the vascular-avascular junction in retinopathy of prematurity (ROP) in infants. We hypothesize that one could view retinal development across the vascular-avascular (V-AV) junction in infants with ROP using portable bedside SDOCT imaging and novel image analysis.
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    12. Optical coherence tomography macular segmentation as predictor for optic atrophy in children with acute papilledema

      Optical coherence tomography macular segmentation as predictor for optic atrophy in children with acute papilledema
      New Spectralis (Heidelberg, Germany) segmentation software allows automatic quantitation of the thickness of each macular layer. We evaluated the role of Spectralis spectral domain optical coherence tomography (SD-OCT) segmentation in children during acute papilledema to predict the subsequent development of optic atrophy.
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    13. Macular segmentation via optical coherence tomography in pediatric optic nerve head drusen and mild papilledema

      Macular segmentation via optical coherence tomography in pediatric optic nerve head drusen and mild papilledema
      Optic nerve head drusen (ONHD) and papilledema in children can lead to partial optic atrophy, and frequently children with idiopathic intracranial hypertension may have both. The purpose of this study is to use SD-OCT to identify possible subclinical atrophy of the inner macula in eyes of children with pseudopapilledema due to ONHD and mild papilledema.
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    14. The macula in pediatric glaucoma: quantifying the inner and outer layers via optical coherence tomography automatic segmentation

      The macula in pediatric glaucoma: quantifying the inner and outer layers via optical coherence tomography automatic segmentation
      Background Recent Spectralis (Heidelberg, Germany) spectral domain optical coherence tomography (SD-OCT) research software can automatically quantify the thickness of each individual retinal layer. The macular ganglion cell layer (GCL) and ganglion cell complex may be more sensitive for detecting glaucoma than the peripapillary retinal nerve fiber layer (pRNFL). The aim of this study was to characterize and compare the volume of each macular layer in the eyes of children with ...
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    15. The macula in pediatric glaucoma: quantifying the inner and outer layers via optical coherence tomography segmentation

      The macula in pediatric glaucoma: quantifying the inner and outer layers via optical coherence tomography segmentation
      Recent Spectralis (Heidelberg, Germany) spectral domain optical coherence tomography research software can quantify the thickness of each individual retinal layer. There is a suggestion that the macular ganglion cell layer (GCL) and ganglion cell complex may be more sensitive for detecting glaucoma than the peripapillary retinal nerve fiber layer (pRNFL). The purpose of this study was to characterize/compare the thickness of each macular layer among children with glaucoma versus ...
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    16. 1-15 of 39 1 2 3 »
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  2. About Sharon F. Freedman

    Sharon F. Freedman

    Sharon F. Freedman, MD, is a Professor of Ophthalmology and Pediatrics and Chief, Pediatric Ophthalmology and Strabismus Service,Glaucoma Service, and the Duke Eye Center, Duke University.