1. Shaosong Zhang

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    1. Mentioned In 37 Articles

    2. Incidence and Clinical Significance of Poststent Optical Coherence Tomography Findings: One-Year Follow-Up Study From a Multicenter Registry

      Incidence and Clinical Significance of Poststent Optical Coherence Tomography Findings: One-Year Follow-Up Study From a Multicenter Registry
      Background Optical coherence tomography (OCT) was recently introduced to optimize percutaneous coronary intervention. However, the exact incidence and significance of poststent OCT findings are unknown. Methods and Results A total of 900 lesions treated with 1001 stents in 786 patients who had postprocedure OCT imaging were analyzed to evaluate the incidence of poststent OCT findings and to identify the OCT predictors for device-oriented clinical end points, including cardiac death, target ...
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    3. Pancoronary Plaque Vulnerability in Patients with Acute Coronary Syndrome and Ruptured Culprit Plaque: A Three-Vessel Optical Coherence Tomography Study

      Pancoronary Plaque Vulnerability in Patients with Acute Coronary Syndrome and Ruptured Culprit Plaque: A Three-Vessel Optical Coherence Tomography Study
      Background Recent studies described different clinical and underlying plaque characteristics between patients with and without plaque rupture presenting with acute coronary syndrome (ACS). In light of the systemic nature of atherosclerosis, we hypothesized that non-culprit plaques might also express different morphological features in these two groups of patients. Methods Thirty-eight patients with ACS who underwent 3-vessel optical coherence tomography (OCT) imaging were identified from the Massachusetts General Hospital OCT Registry ...
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    4. Feature Of The Week 8/4/13: MGH OCT Registry Reports on In Vivo OCT Studies of Plaque Erosion and Calcified Nodule In Acute Coronary Syndrome

      Feature Of The Week 8/4/13: MGH OCT Registry Reports on In Vivo OCT Studies of Plaque Erosion and Calcified Nodule In Acute Coronary Syndrome
      Pathology studies reported that three most common causes of acute coronary syndrome (ACS) or sudden cardiac death are plaque rupture, plaque erosion and calcified nodules. The morphological and clinical characteristics of the underlying pathology of ACS, especially plaque erosion and calcified nodule, have never been well studied in vivo. Using optical coherence tomography, we found that plaque erosions are the substrate for ACS in 31% of patients and calcified nodules ...
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    5. Correlation Between Degree of Neointimal Hyperplasia and Incidence and Characteristics of Neoatherosclerosis as Assessed by Optical Coherence Tomography

      Correlation Between Degree of Neointimal Hyperplasia and Incidence and Characteristics of Neoatherosclerosis as Assessed by Optical Coherence Tomography
      ...n Medical University, Key Laboratory of Myocardial Ischemia, Chinese Ministry of Education, Harbin, China , * Shaosong Zhang, MD, PhD Affiliations + LightLab Imaging Inc., St. Jude Medical Inc., Westford, Massachusetts ,...
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    6. Comparison of Nonculprit Coronary Plaque Characteristics Between Patients With and Without Diabetes : A 3-Vessel Optical Coherence Tomography Study

      Comparison of Nonculprit Coronary Plaque Characteristics Between Patients With and Without Diabetes : A 3-Vessel Optical Coherence Tomography Study
      ...MD^⁎, * Hang Lee, PhD^‡, * Iris McNulty, RN^⁎, * Robert W. Yeh, MD, MSc^⁎, * Rahul Sakhuja, MD, MPP, MSc^§, * Shaosong Zhang, MD, PhD^∥^, ^¶, * Shiro Uemura, MD, PhD^#, * Bo Yu, MD, PhD^††, * Kyoichi Mizuno, MD, PhD^⁎^, ...
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    7. OCT Assessment of Allograft Vasculopathy in Heart Transplant Recipients

      OCT Assessment of Allograft Vasculopathy in Heart Transplant Recipients
      Letter to the editor. Coronary Angiogram, OCT, and IVUS Imaging in a Patient 8 Years After Heart Transplantation (A) Quantitative coronary analysis showed 14% diameter stenosis in the midleft anterior descending artery (arrow) . (B) Optical coherence tomography (OCT) revealed intimal hyperplasia (IH) with thickness of 150 m. (C) Accurate measurement of IH was difficult with intravascular ultrasound (IVUS).
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    8. Validation of a New AnimalModel of Vulnerable Plaques by Intravascular Optical Coherence Tomography In Vivo

      Validation of a New AnimalModel of Vulnerable Plaques by Intravascular Optical Coherence Tomography In Vivo
      We aimed to establish a rabbit model of vulnerable plaques (VPs) with the morphology and component characteristics of human VPs and to evaluate the microstructural features of VPs in vivo using intravascular optical coherence tomography (OCT). Twelve rabbits underwent endothelial denudation of the carotid artery and consumed a 1% high-cholesterol diet (HCD). They were equally divided into two groups: group A (modified needle injury) and group B (balloon injury). OCT ...
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    9. Significance of intraplaque neovascularisation for vulnerability: optical coherence tomography study

      Significance of intraplaque neovascularisation for vulnerability: optical coherence tomography study
      Objectives This study aimed to investigate the role of intraplaque neovascularisation (NV) in culprit lesions and non-culprit lesions of unstable angina pectoris (UAP) and in lesions of stable angina pectoris (SAP) using optical coherence tomography (OCT). Design This study was a retrospective study. Setting The significance of NV for culprit and non-culprit plaques remains unclear. Participants A total of 356 plaques from 92 UAP patients and 25 SAP patients who ...
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    10. Comparison of Incidence and Time Course of Neoatherosclerosis Between Bare Metal Stents and Drug-Eluting Stents Using Optical Coherence Tomography

      Comparison of Incidence and Time Course of Neoatherosclerosis Between Bare Metal Stents and Drug-Eluting Stents Using Optical Coherence Tomography
      ...ons + Biostatistics Center, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts , * Shaosong Zhang, MD, PhD Affiliations + LightLab Imaging, Westford, Massachusetts and Harbin Medical University...
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    11. Nonculprit Plaques in Patients With Acute Coronary Syndromes Have More Vulnerable Features Compared With Those With Non–Acute Coronary Syndromes: A 3-Vessel Optical Coherence Tomography Study

      Nonculprit Plaques in Patients With Acute Coronary Syndromes Have More Vulnerable Features Compared With Those With Non–Acute Coronary Syndromes: A 3-Vessel Optical Coherence Tomography Study
      Background—Patients with acute coronary syndrome (ACS) have a higher incidence of recurrent ischemic events. The aim of this study was to compare the plaque characteristics of non-culprit lesions between ACS and non-ACS patients using optical coherence tomography (OCT) imaging. Methods and Results—Patients who had 3-vessel OCT imaging were selected from the Massachusetts General Hospital (MGH) OCT Registry. MGH registry is a multicenter registry of patients undergoing OCT. The ...
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    12. Feasibility and Safety of the Second-Generation, Frequency Domain Optical Coherence Tomography (FD-OCT): A Multicenter Study

      Feasibility and Safety of the Second-Generation, Frequency Domain Optical Coherence Tomography (FD-OCT): A Multicenter Study
      Abstract: Objectives. This study sought to assess the effectiveness and safety of the second-generation frequency-domain optical coherence tomography (FD-OCT) system. Background. The second-generation FD-OCT was recently developed, with simplified imaging technique and faster acquisition time compared to the first-generation time-domain OCT. However, the safety and effectiveness of the FD-OCT has not been evaluated, and this study was conceived as a pre-approval study for Food and Drug Administration clearance for clinical ...
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    13. 16-30 of 37 « 1 2 3 »
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  2. About Shaosong Zhang

    Shaosong Zhang , MD, is vice president of clinical affairs at Lightlab Imaging. Dr. Zhang joined LightLab Imaging in 2004. He came to LightLab from the Cardiology Division, School of Medicine at Washington University in St. Louis, where he was an Assistant Professor of Medicine. There, he focused his work on the mechanisms of cardiac hypertrophy and heart failure, and authored multiple articles published in journals such as Circulation, Circulation Research and Journal of Clinical Investigation. He attained his M.D. from Harbin Medical University in China. After residency, Dr. Zhang trained in interventional cardiology in China and Japan before becoming an attending physician at Harbin First General Hospital. He then obtained a Ph.D. in Cardiology from the School of Medicine at Niigata University in Japan. He received his post-doctoral training at University of Wisconsin School of Medicine, specializing in endothelial cell function. He is also a faculty member at Harbin Medical University as a visiting professor.