1. Shanghai Jiao Tong University

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    1. Mentioned In 140 Articles

    2. Prediction of the short-term efficacy of anti-VEGF therapy for neovascular age-related macular degeneration using optical coherence tomography angiography

      Prediction of the short-term efficacy of anti-VEGF therapy for neovascular age-related macular degeneration using optical coherence tomography angiography
      Background: To evaluate whether the specific choroidal neovascularization (CNV) characteristics measured using optical coherence tomography angiography (OCTA) can predict the 6-month prognosis of neovascular age-related macular degeneration (nAMD) after anti-vascular endothelial growth factor (anti-VEGF) therapy. Methods: Patients with type 1, type 2, or mixed-type neovascularization (NV) were prospectively included. Participants underwent an initial loading phase of three consecutive monthly intravitreal injections of Conbercept (0.5 mg) and were switched to ...
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    3. Physiologic and compositional coronary artery disease extension in patients with takotsubo syndrome assessed using artificial intelligence: an optical coherence tomography study

      Physiologic and compositional coronary artery disease extension in patients with takotsubo syndrome assessed using artificial intelligence: an optical coherence tomography study
      Background: Takotsubo syndrome (TTS) is an acute and reversible ventricular motion abnormality without epicardial coronary obstruction. Optical flow ratio (OFR) is an approach to evaluate the coronary stenosis significance based on three-dimensional optical coherence tomography (3D-OCT). The aim of this study is to utilize OCT and an artificial intelligence plaque characterization model to show the prevalence and composition of atherosclerotic disease in coronary vessels of patients with TTS. Methods: This ...
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    4. Association of Neutrophil to Lymphocyte Ratio With Plaque Rupture in Acute Coronary Syndrome Patients With Only Intermediate Coronary Artery Lesions Assessed by Optical Coherence Tomography

      Association of Neutrophil to Lymphocyte Ratio With Plaque Rupture in Acute Coronary Syndrome Patients With Only Intermediate Coronary Artery Lesions Assessed by Optical Coherence Tomography
      Objectives: Plaque vulnerability and rupture rather than plaque size are the major cause of clinical events in patients with intermediate coronary lesions. Therefore, the present study was aimed to explore potential markers associated with plaque rupture in acute coronary syndrome (ACS) patients with intermediate coronary lesions. Methods: A total of 82 ACS patients presenting with only intermediate coronary lesions (4070% stenosis demonstrated by quantitative coronary angiography) and no severe stenosis ...
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    5. Development and Clinical Validation of Semi-Supervised Generative Adversarial Networks for Detection of Retinal Disorders in Optical Coherence Tomography Images Using Small Dataset

      Development and Clinical Validation of Semi-Supervised Generative Adversarial Networks for Detection of Retinal Disorders in Optical Coherence Tomography Images Using Small Dataset
      Purpose: To develop and test semi-supervised generative adversarial networks (GANs) that detect retinal disorders on optical coherence tomography (OCT) images using a small-labeled dataset. Methods: From a public database, we randomly chose a small supervised dataset with 400 OCT images (100 choroidal neovascularization, 100 diabetic macular edema, 100 drusen, and 100 normal) and assigned all other OCT images to unsupervised dataset (107,912 images without labeling). We adopted a semi-supervised ...
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    6. Association between Different Grades of Myopic Tractional Maculopathy and OCT-Based Macular Scleral Deformation

      Association between Different Grades of Myopic Tractional Maculopathy and OCT-Based Macular Scleral Deformation
      Purpose: To investigate the characteristics of macular outward scleral height (MOSH) in different grades of myopic tractional maculopathy (MTM) and explore the risk factors for MTM. Methods: A total of 188 eyes (188 participants) with high myopia were divided into the no MTM (nMTM) group and the MTM group, which was further graded into foveoschisis, foveal detachment, full-thickness macular hole, and macular hole with retinal detachment. Swept-source optical coherence tomography ...
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    7. Optical coherence tomography angiography for the detection and evaluation of optic disc neovascularization: a retrospective, observational study

      Optical coherence tomography angiography for the detection and evaluation of optic disc neovascularization: a retrospective, observational study
      Background: To assess and characterize neovascularization of the optic disc (NVD) using optical coherence tomography angiography (OCTA) and different OCTA-based methods. Methods: This retrospective, observational study included patients who were suspected of having early PDR with no presence of clinically apparent neovascularization (NV) bur were clinically diagnosed with proliferative diabetic retinopathy (PDR), or severe NPDR. Patients underwent standard clinical examinations and OCTA imaging using a 6 6 montage scan. Two ...
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    8. Three-Dimensional Choroidal Vascularity Index in High Myopia Using Swept-Source Optical Coherence Tomography

      Three-Dimensional Choroidal Vascularity Index in High Myopia Using Swept-Source Optical Coherence Tomography
      Purpose: To characterize the choroidal vasculature in high myopic eyes by three-dimensional choroidal vascularity index (CVI) using swept-source optical coherence tomography (SS-OCT). Subjects and methods: A cross-sectional observational study of 98 right eyes from 98 consecutive nonpathological myopic patients, including 46 high myopes (HM) and 52 low to moderate myopes (LMM). OCT and OCT angiography covering an area of 6 6 mm 2 centered on the fovea was conducted with ...
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    9. Combined Use of Multiple Intravascular Imaging Techniques in Acute Coronary Syndrome

      Combined Use of Multiple Intravascular Imaging Techniques in Acute Coronary Syndrome
      Recent advances in intravascular imaging techniques have made it possible to assess the culprit lesions of acute coronary syndrome (ACS) in the clinical setting. Intravascular ultrasound (IVUS) is the most commonly used intravascular imaging technique that provides cross-sectional images of coronary arteries. IVUS can assess plaque burden and vessel remodeling. Optical coherence tomography (OCT) is a high-resolution (10 m) intravascular imaging technique that uses near-infrared light. OCT can identify key ...
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    10. Optical Coherence Tomography Classification Systems for Diabetic Macular Edema and Their Associations With Visual Outcome and Treatment Responses

      Optical Coherence Tomography Classification Systems for Diabetic Macular Edema and Their Associations With Visual Outcome and Treatment Responses
      Optical coherence tomography (OCT) is an invaluable imaging tool in detecting and assessing diabetic macular edema (DME). Over the past decade, there have been different proposed OCT-based classification systems for DME. In this review, we present an update of spectral-domain OCT (SDOCT)-based DME classifications over the past 5 years. In addition, we attempt to summarize the proposed OCT qualitative and quantitative parameters from different classification systems in relation to ...
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    11. Association of Microvasculature and Macular Sensitivity in Idiopathic Macular Epiretinal Membrane: Using OCT Angiography and Microperimetry

      Association of Microvasculature and Macular Sensitivity in Idiopathic Macular Epiretinal Membrane: Using OCT Angiography and Microperimetry
      Purpose: To investigate the correlation between retinal capillary structure and macular function in patients with idiopathic epiretinal membrane (iERM) by using optical coherence tomography angiography (OCTA) and microperimetry. Methods: This retrospective and observational study included 30 idiopathic ERM eyes of 30 consecutive patients. OCTA was performed to evaluate macular microvasculature including the superficial capillary plexus, deep capillary plexus, and foveal avascular zone. Best corrected visual acuity (BCVA) and microperimetry were ...
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    12. Choroidal Changes in Eyes With Polypoidal Choroidal Vasculopathy After Anti-VEGF Therapy Imaged With Swept-Source OCT Angiography

      Choroidal Changes in Eyes With Polypoidal Choroidal Vasculopathy After Anti-VEGF Therapy Imaged With Swept-Source OCT Angiography
      Purpose: Swept-source optical coherence tomography angiography was used to investigate choroidal changes and their association with pigment epithelial detachments (PEDs) in eyes with polypoidal choroidal vasculopathy (PCV) after treatment with vascular endothelial growth factor (VEGF) inhibitors. Methods: Patients with treatment-nave PCV were included and underwent anti-VEGF therapy. Mean choroidal thickness (MCT), choroidal vascularity index (CVI), and PED volume measurements were obtained before and after treatment. Results: Thirty-four treatment-nave PCV eyes ...
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    13. Assessment of the retinal vasculature in healthy Chinese preschool children aged 4-6 years old using optical coherence tomography angiography

      Assessment of the retinal vasculature in healthy Chinese preschool children aged 4-6 years old using optical coherence tomography angiography
      Purpose: To establish normal parameters of macular and optic disc vasculature by optical coherence tomography angiography (OCTA) in healthy preschool children aged 4-6 years old in China. OCTA reflects retinal metabolism and development in children at these ages and could be used clinically and in future studies to aid diagnosis and prediction of retinal abnormalities and developmental stagnation. Methods: In this cross-sectional study, we measured foveal, parafoveal, and perifoveal vessel ...
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    14. Optical Coherence Tomography-Derived Changes in Plaque Structural Stress Over the Cardiac Cycle: A New Method for Plaque Biomechanical Assessment

      Optical Coherence Tomography-Derived Changes in Plaque Structural Stress Over the Cardiac Cycle: A New Method for Plaque Biomechanical Assessment
      Introduction: Cyclic plaque structural stress has been hypothesized as a mechanism for plaque fatigue and eventually plaque rupture. A novel approach to derive cyclic plaque stress in vivo from optical coherence tomography (OCT) is hereby developed. Materials and Methods: All intermediate lesions from a previous OCT study were enrolled. OCT cross-sections at representative positions within each lesion were selected for plaque stress analysis. Detailed plaque morphology, including plaque composition, lumen ...
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    15. Optical coherence tomography and coronary revascularization: from indication to procedural optimization

      Optical coherence tomography and coronary revascularization: from indication to procedural optimization
      Angiography alone is the most commonly used imaging modality for guidance of percutaneous coronary interventions. Angiography is limited, however, by several factors, including that it only portrays a low resolution, two-dimensional outline of the lumen and does not inform on plaque composition and functional stenosis severity. Optical coherence tomography (OCT) is an intracoronary imaging technique that has superior spatial resolution compared to all other imaging modalities. High-resolution imaging of the ...
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    16. Noise reduction by adaptive-SIN filtering for retinal OCT images

      Noise reduction by adaptive-SIN filtering for retinal OCT images
      Optical coherence tomography (OCT) images is widely used in ophthalmic examination, but their qualities are often affected by noises. Shearlet transform has shown its effectiveness in removing image noises because of its edge-preserving property and directional sensitivity. In the paper, we propose an adaptive denoising algorithm for OCT images. The OCT noise is closer to the Poisson distribution than the Gaussian distribution, and shearlet transform assumes additive white Gaussian noise ...
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  2. About Shanghai Jiao Tong University

    Shanghai Jiao Tong University

    Shanghai Jiao Tong University sometimes referred to as Shanghai Jiaotong University or Jiaotong University, is a top public research university located in Shanghai, renowned as one of the oldest and most prestigious selective universities in China. It is a member of the C9 League in China