1. Shanghai Jiao Tong University

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    1. Mentioned In 154 Articles

    2. A moderate dosage of coffee causes acute retinal capillary perfusion decrease in healthy young individuals

      A moderate dosage of coffee causes acute retinal capillary perfusion decrease in healthy young individuals
      im: Caffeinated beverages are very popular across populations and cultures, but quantitative evidence of the acute effects of moderate coffee doses on retinal perfusion is sparse and contradicting. Thus, the aim of this randomized, cross-over and parallel-group design study was to investigate whether moderate consumption of coffee alters macular retinal capillary perfusion in young healthy individuals. Methods: Twenty-seven young healthy individuals were recruited for this study. Acute changes in retinal ...
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    3. An overview of artificial intelligence in diabetic retinopathy and other ocular diseases

      An overview of artificial intelligence in diabetic retinopathy and other ocular diseases
      Artificial intelligence (AI), also known as machine intelligence, is a branch of science that empowers machines using human intelligence. AI refers to the technology of rendering human intelligence through computer programs. From healthcare to the precise prevention, diagnosis, and management of diseases, AI is progressing rapidly in various interdisciplinary fields, including ophthalmology. Ophthalmology is at the forefront of AI in medicine because the diagnosis of ocular diseases heavy reliance on ...
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    4. Monte Carlo-based full-wavelength simulator of Fourier-domain optical coherence tomography

      Monte Carlo-based full-wavelength simulator of Fourier-domain optical coherence tomography
      Monte Carlo (MC) simulation has been widely used to study imaging procedures, including Fourier-domain optical coherence tomography (FD-OCT). Despite the broadband nature of FD-OCT, the results obtained at a single wavelength are often used in previous studies. Some wavelength-relied imaging applications, such as spectroscopic OCT (S-OCT), are unlikely to be simulated in this way due to the lack of information from the entire spectrum. Here, we propose a novel simulator ...
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    5. Progress in Probe-Based Sensing Techniques for In Vivo Diagnosis

      Progress in Probe-Based Sensing Techniques for In Vivo Diagnosis
      Advancements in robotic surgery help to improve the endoluminal diagnosis and treatment with minimally invasive or non-invasive intervention in a precise and safe manner. Miniaturized probe-based sensors can be used to obtain information about endoluminal anatomy, and they can be integrated with medical robots to augment the convenience of robotic operations. The tremendous benefit of having this physiological information during the intervention has led to the development of a variety ...
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    6. Risk Stratification in Acute Coronary Syndrome by Comprehensive Morphofunctional Assessment With Optical Coherence Tomography

      Risk Stratification in Acute Coronary Syndrome by Comprehensive Morphofunctional Assessment With Optical Coherence Tomography
      Background: Artificial intelligence enables simultaneous evaluation of plaque morphology and computational physiology from optical coherence tomography (OCT). Objectives: This study sought to appraise the predictive value of major adverse cardiovascular events (MACE) by combined plaque morphology and computational physiology. Methods: A total of 604 patients with acute coronary syndrome who underwent OCT imaging in 1 nonculprit vessel during index coronary angiography were retrospectively enrolled. A novel morphologic index, named the ...
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    7. Dynamic analysis of iris changes and a deep learning system for automated angle-closure classification based on AS-OCT videos

      Dynamic analysis of iris changes and a deep learning system for automated angle-closure classification based on AS-OCT videos
      Background: To study the association between dynamic iris change and primary angle-closure disease (PACD) with anterior segment optical coherence tomography (AS-OCT) videos and develop an automated deep learning system for angle-closure screening as well as validate its performance. Methods: A total of 369 AS-OCT videos (19,940 frames)-159 angle-closure subjects and 210 normal controls (two datasets using different AS-OCT capturing devices)-were included. The correlation between iris changes (pupil ...
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    8. In-hospital heart failure in patients with Takotsubo cardiomyopathy due to coronary artery disease: An artificial intelligence and optical coherence tomography study

      In-hospital heart failure in patients with Takotsubo cardiomyopathy due to coronary artery disease: An artificial intelligence and optical coherence tomography study
      Background: Takotsubo syndrome (TTS) is often associated with symptoms of heart failure (HF) during the acute phase of the disease. 3-dimensional optical coherence tomography (OCT) may be used to assess the extent of angiographically silent underlying coronary artery disease (CAD). This study aims to use an artificial intelligence algorithm to analyze OCT findings and to determine whether the presence of pre-existing CAD predisposes TTS patients to present HF at admission ...
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    9. Radial wall strain: a novel angiographic measure of plaque composition and vulnerability

      Radial wall strain: a novel angiographic measure of plaque composition and vulnerability
      Background: The lipid-to-cap ratio (LCR) and thin-cap fibroatheroma (TCFA) derived from optical coherence tomography (OCT) are indicative of plaque vulnerability. Aims: We aimed to explore the association of a novel method to estimate radial wall strain (RWS) from angiography with plaque composition and features of vulnerability assessed by OCT. Methods: Anonymised data from patients with intermediate stenosis who underwent coronary angiography (CAG) and OCT were analysed in a core laboratory ...
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    10. Effect of ocular magnification on macular choroidal thickness measurements made using optical coherence tomography in children

      Effect of ocular magnification on macular choroidal thickness measurements made using optical coherence tomography in children
      Purpose/aim of the study: To evaluate the relationship between ocular magnification correction and macular choroidal thickness (ChT) measurements in children, and to demonstrate when ocular magnification correction is necessary. Materials and methods: Chinese children aged 6-9 years with various refractive statuses were included. Swept-source optical coherence tomography was used to measure macular ChT. A self-designed program was adopted to simulate ChT changes in each sector of the ETDRS grid ...
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    11. The Efficacy of Anti-VEGF Therapy for Putative or Visible CNV in Central Serous Chorioretinopathy by Optical Coherence Tomography Angiography

      The Efficacy of Anti-VEGF Therapy for Putative or Visible CNV in Central Serous Chorioretinopathy by Optical Coherence Tomography Angiography
      ... The study was approved by the Clinical Research Ethical Committee of Shanghai General Hospital affiliated to Shanghai Jiao Tong University, Shanghai, China (Permit No. 2020KY205-2). The participants underwent full ophth...
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    12. Changes in dimensions and functions of crystalline lens in high myopia using CASIA2 optical coherence tomography

      Changes in dimensions and functions of crystalline lens in high myopia using CASIA2 optical coherence tomography
      Introduction: Crystalline lens is the major dioptric component and varies with refractive status. In this study, we aim to evaluate the changes of dimensions and functions of crystalline lens in high myopia and its correlated variables using CASIA2 swept-source optical coherence tomography (SS-OCT). Methods: One hundred and thirty eligible eyes of myopic patients from 18-40 years old were enrolled and divided into low-to-moderate myopia (LMM) and high myopia (HM) groups ...
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    13. Relationship Between Optical Coherence Tomography and Anterior Chamber Depth after Pupillary Dilation in Primary Angle Closure Suspects

      Relationship Between Optical Coherence Tomography and Anterior Chamber Depth after Pupillary Dilation in Primary Angle Closure Suspects
      Precis: Anterior chamber depth change after pupillary dilation is correlated with lens vault and anterior chamber width, as observed by SS-OCT at both horizontal and vertical scans in patients with PACS and cataract. Purpose: To evaluate the association between anterior chamber depth (ACD) and other anterior chamber parameters after pharmacological dilation in patients with primary angle closure suspect (PACS) and cataract. Patients and Methods: Swept-source optical coherence tomography (SS-OCT) was ...
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    14. Choroid automatic segmentation and thickness quantification on swept-source optical coherence tomography images of highly myopic patients

      Choroid automatic segmentation and thickness quantification on swept-source optical coherence tomography images of highly myopic patients
      Background: Thinning of the choroid has been linked with various ocular diseases, including high myopia (HM), which can lead to visual impairment. Although various artificial intelligence (AI) algorithms have been developed to quantify choroidal thickness (ChT), few patients with HM were included in their development. The choroid in patients with HM tends to be thinner than that of normal patients, making it harder to segment. Therefore, in this study, we ...
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    15. Prediction of the short-term efficacy of anti-VEGF therapy for neovascular age-related macular degeneration using optical coherence tomography angiography

      Prediction of the short-term efficacy of anti-VEGF therapy for neovascular age-related macular degeneration using optical coherence tomography angiography
      Background: To evaluate whether the specific choroidal neovascularization (CNV) characteristics measured using optical coherence tomography angiography (OCTA) can predict the 6-month prognosis of neovascular age-related macular degeneration (nAMD) after anti-vascular endothelial growth factor (anti-VEGF) therapy. Methods: Patients with type 1, type 2, or mixed-type neovascularization (NV) were prospectively included. Participants underwent an initial loading phase of three consecutive monthly intravitreal injections of Conbercept (0.5 mg) and were switched to ...
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  2. About Shanghai Jiao Tong University

    Shanghai Jiao Tong University

    Shanghai Jiao Tong University sometimes referred to as Shanghai Jiaotong University or Jiaotong University, is a top public research university located in Shanghai, renowned as one of the oldest and most prestigious selective universities in China. It is a member of the C9 League in China