1. Shanghai Jiao Tong University

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    1. Mentioned In 56 Articles

    2. Interchangeability and reliability of macular perfusion parameter measurements using optical coherence tomography angiography

      Interchangeability and reliability of macular perfusion parameter measurements using optical coherence tomography angiography
      Aim The aim of the study was to investigate the interchangeability and reliability of macular perfusion measurements using optical coherence tomography angiography. Methods A prospective cross-sectional observational study. Healthy adult Chinese subjects were recruited. Macular perfusion parameters were automatically analysed by software included in a spectral-domain optical coherence tomography system. The vessel density (VD) of the whole, parafovea, superior-hemi, inferior-hemi, fovea, temporal, superior, nasal and inferior quadrants as well as ...
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    3. Visualization of extensive intraplaque neovascularization by optical coherence tomography

      Visualization of extensive intraplaque neovascularization by optical coherence tomography
      Inflammation plays a key role in pathogenesis and progression of atherosclerosis (1) . Advent of novel intravascular imaging tools such as Optical Coherence Tomography (OCT) has led to visualization of coronary atherosclerotic plaque characteristics in vivo that were previously seen only on histology. Herein we discuss a case of extensive neovascularization, a feature that imparts vulnerability to atherosclerotic plaque in the coronary artery, as seen by two- and three-dimensional OCT images ...
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    4. Repeatability and Reproducibility of Foveal Avascular Zone Area Measurements Using AngioPlex Spectral Domain Optical Coherence Tomography Angiography in Healthy Subjects

      Repeatability and Reproducibility of Foveal Avascular Zone Area Measurements Using AngioPlex Spectral Domain Optical Coherence Tomography Angiography in Healthy Subjects
      Purpose: The aim of this study was to evaluate the repeatability and reproducibility of foveal avascular zone (FAZ) area measurements using AngioPlex spectral domain optical coherence tomography (OCT) angiography in normal subjects. Methods: Twenty-two healthy subjects (25 eyes) underwent FAZ area measurements with AngioPlex OCT. Each volunteer was separately examined 3 consecutive times by the 2 experienced observers. The FAZ area was measured using ImageJ software. Intraobserver repeatability was evaluated ...
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    5. Macular changes of neuromyelitis optica through spectral-domain optical coherence tomography

      Macular changes of neuromyelitis optica through spectral-domain optical coherence tomography
      AIM : To evaluate the thickness of the retinal layers in the macula using spectral-domain optical coherence tomography (SD-OCT) in patients with neuromyelitis optica (NMO). METHODS : Spectralis SD-OCT, utilizing automated macular layer segmentation, was performed in 26 NMO patients and 26 healthy controls. Visual function including visual field tests and pattern visual evoked potential were recorded in study subjects. RESULTS : Forty-one eyes from 26 NMO patients and 52 eyes from 26 ...
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    6. Optical Coherence Tomography Angiography Characteristics of Fovea in Residual Subfoveal Perfluorocarbon Liquid Eye

      Optical Coherence Tomography Angiography Characteristics of Fovea in Residual Subfoveal Perfluorocarbon Liquid Eye
      The authors report a case of optical coherence tomography angiography (OCTA) features of retina and choriocapillaris before and after the surgical removal of a subfoveal perfluorocarbon liquid (PFCL) bubble. Before the surgery, the fovea avascular zone (FAZ) of both superficial and deep inner retinal layers (SRL/DRL) dramatically enlarged. However, after the removal, the FAZ continually decreased in both layers, even becoming close to normal in size. The abnormal choriocapillaris ...
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    7. Endoscopic optical coherence tomography using compressive sensing

      Endoscopic optical coherence tomography using compressive sensing
      Conventionally endoscopic OCT images are reconstructed by uniform sampling in both axial and transverse direction of the image. To shorten the scanning time and reduce the acquisition data, we propose to sparsely sample the axial scans and use compressive sensing (CS) to reconstruct the full endoscopic OCT image with randomly chosen axial scans that are much less than conventional Nyquist criteria requirement. And we study the ratio of sparse sampling ...
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    8. Imaging hemodynamic response after ischemic stroke in mouse cortex using visible-light optical coherence tomography

      Imaging hemodynamic response after ischemic stroke in mouse cortex using visible-light optical coherence tomography
      Visible-light optical coherence tomography (Vis-OCT) is an emerging technology that can image hemodynamic response in microvasculature. Vis-OCT can retrieve blood oxygen saturation (sO 2 ) mapping using intrinsic optical absorption contrast while providing high-resolution anatomical vascular structures at the same time. To improve the accuracy of Vis-OCT oximetry on vessels embedded in highly scattering medium, i.e., brain cortex, we developed and formulated a novel dual-depth sampling and normalization strategy that ...
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    9. Relationship Between Retinal Perfusion and Retinal Thickness in Healthy Subjects: An Optical Coherence Tomography Angiography Study

      Relationship Between Retinal Perfusion and Retinal Thickness in Healthy Subjects: An Optical Coherence Tomography Angiography Study
      Purpose : To investigate the relationship between retinal perfusion and retinal thickness in the peripapillary and macular areas of healthy subjects. Methods : Using spectral-domain optic coherence tomography and split-spectrum amplitude decorrelation angiography (SSADA) algorithm, retinal perfusion and retinal thicknesses in the macular and peripapillary areas were measured in healthy volunteers, and correlations among these variables were analyzed. Results : Overall, 64 subjects (121 eyes) including 28 males and 36 females with a ...
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    10. Choroidal and Retinal Thickness in Children with Different Refractive Status Measured by Swept-Source Optical Coherence Tomography

      Choroidal and Retinal Thickness in Children with Different Refractive Status Measured by Swept-Source Optical Coherence Tomography
      Purpose To investigate the choroidal and retinal thickness in myopic, emmetropic, and hyperopic Chinese children by swept-source longer-wavelength optical coherence tomography. Design Cross-sectional study. Methods Two-hundred-and-seventy-six school children aged 713 years underwent comprehensive ophthalmic examinations, including cycloplegic refraction, and swept-source optical coherence tomography measurements. The thickness of the choroid, retina, ganglion cell layer, and nerve fiber layer were compared among children of different refractive status. The topographic variation and factors ...
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    11. The Diagnostic Accuracy of Optical Coherence Tomography Angiography for Neovascular Age-Related Macular Degeneration: A Comparison with Fundus Fluorescein Angiography

      The Diagnostic Accuracy of Optical Coherence Tomography Angiography for Neovascular Age-Related Macular Degeneration: A Comparison with Fundus Fluorescein Angiography
      Purpose. To describe the morphological characteristics and efficacy of OCTA in detecting CNV in nAMD. We retrospectively reviewed 53 patients (86 eyes) with suspected CNV secondary to wet AMD. All the patients underwent a multimodal assessment for CNV. Two independent readers calculated the sensitivity and specificity of OCTA in detecting CNV compared with FA. A qualitative analysis of OCTA was also performed to describe the morphological appearance of CNV. Among ...
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    12. Macular Thickness in Myopia: An OCT Study of Young Chinese Patients

      Macular Thickness in Myopia: An OCT Study of Young Chinese Patients
      Purposes : To investigate macular thickness (MT) in young myopic Chinese patients using Spectralis optical coherence tomography (OCT) and to assess its association with gender, axial length (AL), spherical equivalent (SE), and intraocular pressure (IOP). Methods : Included in this study were 133 myopic Chinese patients, aged 1830 years. All underwent complete ophthalmic examinations and Spectralis OCT. Inner, central, and outer foveal regions of the macula were measured. Results : The central fovea ...
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    13. Compensation of optical source phase noise in long-range OFDR by using an optical fiber delay loop

      Compensation of optical source phase noise in long-range OFDR by using an optical fiber delay loop
      We demonstrate a novel method to compensate the optical source phase noise in long-range OFDR by using an optical fiber delay loop (OFDL). In this method, a 10 km OFDL is incorporated in the reference interferometer of the reflectometry. A frequency shifter is used to count the circulation rounds of the light traveling in OFDL. The preliminary proof-of-concept experiment shows a successful compensation effect and an 11 cm spatial resolution ...
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    14. Impact of Side Branch Modeling on Computation of Endothelial Shear Stress in Coronary Artery Disease Coronary Tree Reconstruction by Fusion of 3D Angiography and OCT

      Impact of Side Branch Modeling on Computation of Endothelial Shear Stress in Coronary Artery Disease Coronary Tree Reconstruction by Fusion of 3D Angiography and OCT
      Background Computational fluid dynamics allow virtual evaluation of coronary physiology and shear stress (SS). Most studies hitherto assumed the vessel as a single conduit without accounting for the flow through side branches. Objectives This study sought to develop a new approach to reconstruct coronary geometry that also computes outgoing flow through side branches in hemodynamic and biomechanical calculations, using fusion of optical coherence tomography (OCT) and 3-dimensional (3D) angiography. Methods ...
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    15. Dual band dual focus optical coherence tomography for imaging the whole eye segment

      Dual band dual focus optical coherence tomography for imaging the whole eye segment
      We developed an improved dual band dual focus spectral domain optical coherence tomography (SD-OCT) for in vivo 2D/3D imaging of the whole eye segment, including the whole anterior segment and retina. The system featured two OCT channels with two different bands centered at 840 nm and 1050 nm, which were designed to image the retina and the anterior segments of the eye, respectively. By combing the two probe light ...
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    16. Miniaturized magnetic-driven scanning probe for endoscopic optical coherence tomography

      Miniaturized magnetic-driven scanning probe for endoscopic optical coherence tomography
      We designed and implemented a magnetic-driven scanning (MDS) probe for endoscopic optical coherence tomography (OCT). The probe uses an externally-driven tiny magnet in the distal end to achieve unobstructed 360-degree circumferential scanning at the side of the probe. The design simplifies the scanning part inside the probe and thus allows for easy miniaturization and cost reduction. We made a prototype probe with an outer diameter of 1.4 mm and ...
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  2. About Shanghai Jiao Tong University

    Shanghai Jiao Tong University

    Shanghai Jiao Tong University sometimes referred to as Shanghai Jiaotong University or Jiaotong University, is a top public research university located in Shanghai, renowned as one of the oldest and most prestigious selective universities in China. It is a member of the C9 League in China