1. Shanghai Jiao Tong University

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    1. Mentioned In 63 Articles

    2. Quantification of Macular Vascular Density Using Optical Coherence Tomography Angiography and Its Relationship with Retinal Thickness in Myopic Eyes of Young Adults

      Quantification of Macular Vascular Density Using Optical Coherence Tomography Angiography and Its Relationship with Retinal Thickness in Myopic Eyes of Young Adults
      Purpose . To quantify macular vascular density using optical coherence tomography angiography (OCTA) and to investigate its relationship with retinal thickness in myopic eyes of young adults. Methods . In this cross-sectional study, 268 myopic eyes without pathological changes were recruited and divided into three groups: mild myopia ( ), moderate myopia ( ), and high myopia ( ). Macular vascular density was quantified by OCTA and compared among three groups. Average retinal thickness, central subfield thickness, and ...
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    3. Paravascular abnormalities observed by spectral domain optical coherence tomography are risk factors for retinoschisis in eyes with high myopia

      Paravascular abnormalities observed by spectral domain optical coherence tomography are risk factors for retinoschisis in eyes with high myopia
      ...2229); The National Science Fund for Distinguished Young Scholars (81425006); Translational Medicine Grant of Shanghai Jiao Tong University, School of Medicine (15ZH4005); Shanghai Engineering Center for Visual Science a...
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    4. In-stent fractional flow reserve variations and related optical coherence tomography findings: the FFR–OCT co-registration study

      In-stent fractional flow reserve variations and related optical coherence tomography findings: the FFR–OCT co-registration study
      We sought to assess in-stent variations in fractional flow reserve (FFR) in patients with previous percutaneous coronary intervention (PCI) and to associate any drop in FFR with findings by optical coherence tomography (OCT) imaging. Suboptimal post-PCI FFR values were previously associated with poor outcomes. It is not known to which extent in-stent pressure loss contributes to reduced FFR. In this single-arm observational study, 26 patients who previously underwent PCI with ...
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    5. Retinal pulse wave velocity measurement using spectral-domain optical coherence tomography

      Retinal pulse wave velocity measurement using spectral-domain optical coherence tomography
      The human eyes provide a natural window for noninvasive measurement of the pulse wave velocity (PWV) of small arteries. By measuring the retinal PWV, the stiffness of small arteries can be assessed, which may better detect early vascular diseases. Therefore, retinal PWV measurement has attracted increasing attention. In this study, a jump-scanning method was proposed for non-invasive measurement of retinal PWV using spectral-domain OCT. The jump-scanning method uses the phase-resolved ...
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    6. Microvasculature dropout detected by the optical coherence tomography angiography in nonarteritic anterior ischemic optic neuropathy

      Microvasculature dropout detected by the optical coherence tomography angiography in nonarteritic anterior ischemic optic neuropathy
      Objective To investigate microcirculation characteristics of peripapillary superficial retina and optic disc in eyes with nonarteritic anterior ischemic optic neuropathy (NAION) using optical coherence tomography angiography (OCTA). Methods Forty-one eyes of 30 NAION patients and 30 eyes of 30 normal subjects were evaluated with OCTA (AngioVue, Optovue). The whole vessel density, inside disc vessel density, peripapillary vessel density, and vessel densities based on the sectorial division in the nerve head ...
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    7. Choroidal Variations in Diabetic Macular Edema: Fluorescein Angiography and Optical Coherence Tomography

      Choroidal Variations in Diabetic Macular Edema: Fluorescein Angiography and Optical Coherence Tomography
      Purposes : To (i) evaluate variations in choroidal thickness (CT) and choroidal volume (CV) in diabetic macular edema (DME), as demonstrated by fluorescein angiography (FA) and enhanced depth-imaging (EDI) optical coherence tomography (OCT) (EDI-OCT) and (ii) correlate these variations with visual acuity. Methods : This study was a retrospective observational case series of patients with diabetic retinopathy (DR) and DME. The study groups comprised 77 DR patients ( n = 87), all of whom ...
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    8. Interchangeability and reliability of macular perfusion parameter measurements using optical coherence tomography angiography

      Interchangeability and reliability of macular perfusion parameter measurements using optical coherence tomography angiography
      Aim The aim of the study was to investigate the interchangeability and reliability of macular perfusion measurements using optical coherence tomography angiography. Methods A prospective cross-sectional observational study. Healthy adult Chinese subjects were recruited. Macular perfusion parameters were automatically analysed by software included in a spectral-domain optical coherence tomography system. The vessel density (VD) of the whole, parafovea, superior-hemi, inferior-hemi, fovea, temporal, superior, nasal and inferior quadrants as well as ...
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    9. Visualization of extensive intraplaque neovascularization by optical coherence tomography

      Visualization of extensive intraplaque neovascularization by optical coherence tomography
      Inflammation plays a key role in pathogenesis and progression of atherosclerosis (1) . Advent of novel intravascular imaging tools such as Optical Coherence Tomography (OCT) has led to visualization of coronary atherosclerotic plaque characteristics in vivo that were previously seen only on histology. Herein we discuss a case of extensive neovascularization, a feature that imparts vulnerability to atherosclerotic plaque in the coronary artery, as seen by two- and three-dimensional OCT images ...
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    10. Repeatability and Reproducibility of Foveal Avascular Zone Area Measurements Using AngioPlex Spectral Domain Optical Coherence Tomography Angiography in Healthy Subjects

      Repeatability and Reproducibility of Foveal Avascular Zone Area Measurements Using AngioPlex Spectral Domain Optical Coherence Tomography Angiography in Healthy Subjects
      Purpose: The aim of this study was to evaluate the repeatability and reproducibility of foveal avascular zone (FAZ) area measurements using AngioPlex spectral domain optical coherence tomography (OCT) angiography in normal subjects. Methods: Twenty-two healthy subjects (25 eyes) underwent FAZ area measurements with AngioPlex OCT. Each volunteer was separately examined 3 consecutive times by the 2 experienced observers. The FAZ area was measured using ImageJ software. Intraobserver repeatability was evaluated ...
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    11. Macular changes of neuromyelitis optica through spectral-domain optical coherence tomography

      Macular changes of neuromyelitis optica through spectral-domain optical coherence tomography
      AIM : To evaluate the thickness of the retinal layers in the macula using spectral-domain optical coherence tomography (SD-OCT) in patients with neuromyelitis optica (NMO). METHODS : Spectralis SD-OCT, utilizing automated macular layer segmentation, was performed in 26 NMO patients and 26 healthy controls. Visual function including visual field tests and pattern visual evoked potential were recorded in study subjects. RESULTS : Forty-one eyes from 26 NMO patients and 52 eyes from 26 ...
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    12. Optical Coherence Tomography Angiography Characteristics of Fovea in Residual Subfoveal Perfluorocarbon Liquid Eye

      Optical Coherence Tomography Angiography Characteristics of Fovea in Residual Subfoveal Perfluorocarbon Liquid Eye
      The authors report a case of optical coherence tomography angiography (OCTA) features of retina and choriocapillaris before and after the surgical removal of a subfoveal perfluorocarbon liquid (PFCL) bubble. Before the surgery, the fovea avascular zone (FAZ) of both superficial and deep inner retinal layers (SRL/DRL) dramatically enlarged. However, after the removal, the FAZ continually decreased in both layers, even becoming close to normal in size. The abnormal choriocapillaris ...
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    13. Endoscopic optical coherence tomography using compressive sensing

      Endoscopic optical coherence tomography using compressive sensing
      Conventionally endoscopic OCT images are reconstructed by uniform sampling in both axial and transverse direction of the image. To shorten the scanning time and reduce the acquisition data, we propose to sparsely sample the axial scans and use compressive sensing (CS) to reconstruct the full endoscopic OCT image with randomly chosen axial scans that are much less than conventional Nyquist criteria requirement. And we study the ratio of sparse sampling ...
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    14. Imaging hemodynamic response after ischemic stroke in mouse cortex using visible-light optical coherence tomography

      Imaging hemodynamic response after ischemic stroke in mouse cortex using visible-light optical coherence tomography
      Visible-light optical coherence tomography (Vis-OCT) is an emerging technology that can image hemodynamic response in microvasculature. Vis-OCT can retrieve blood oxygen saturation (sO 2 ) mapping using intrinsic optical absorption contrast while providing high-resolution anatomical vascular structures at the same time. To improve the accuracy of Vis-OCT oximetry on vessels embedded in highly scattering medium, i.e., brain cortex, we developed and formulated a novel dual-depth sampling and normalization strategy that ...
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    15. Relationship Between Retinal Perfusion and Retinal Thickness in Healthy Subjects: An Optical Coherence Tomography Angiography Study

      Relationship Between Retinal Perfusion and Retinal Thickness in Healthy Subjects: An Optical Coherence Tomography Angiography Study
      Purpose : To investigate the relationship between retinal perfusion and retinal thickness in the peripapillary and macular areas of healthy subjects. Methods : Using spectral-domain optic coherence tomography and split-spectrum amplitude decorrelation angiography (SSADA) algorithm, retinal perfusion and retinal thicknesses in the macular and peripapillary areas were measured in healthy volunteers, and correlations among these variables were analyzed. Results : Overall, 64 subjects (121 eyes) including 28 males and 36 females with a ...
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  2. About Shanghai Jiao Tong University

    Shanghai Jiao Tong University

    Shanghai Jiao Tong University sometimes referred to as Shanghai Jiaotong University or Jiaotong University, is a top public research university located in Shanghai, renowned as one of the oldest and most prestigious selective universities in China. It is a member of the C9 League in China