Ping An completes multi-center clinical trials for world's first intelligent OCT retinal disease screening system
...al of Fudan University in Shanghai, Shanghai First People's Hospital of Shanghai Jiao Tong University, and Shanghai Tenth People's Hospital of Tongji University.
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Retinal and choroidal vascular changes in coronary heart disease: an optical coherence tomography angiography study
To reveal the association between retinal microvasculature changes and coronary heart disease (CHD), we assessed the full retinal thicknesses of eight areas, the vessel density of four layers (consisting of nine areas) and the flow area in two layers with optical coherence tomography angiography (OCTA) in CHD patients and healthy controls. The mean vessel density of several layers was significantly lower in patients. The difference in choroid capillary flow (negative ...
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Case Report: Optical Coherence Tomography Can Find Typical Features in Pregnancy-induced Hypertension with Retinopathy
SIGNIFICANCE Pregnancy-induced hypertension is a unique yet common complication in pregnant women and may cause retinopathy. Optical coherence tomography (OCT) may help find the features of retinopathy that are difficult to observe through fundus examination. Not all patients can fully recover from retinopathy. PURPOSE This report describes a case of pregnancy-induced hypertension with retinopathy and represents the features of retinopathy in OCT and fundus fluorescein angiography. CASE REPORT A 29-year-old ...
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Shanghai Jiao Tong University
Appearance of Polypoidal Lesions in Patients With Polypoidal Choroidal Vasculopathy Using Swept-Source Optical Coherence Tomographic Angiography
Importance Polypoidal choroidal vasculopathy (PCV) is a major cause of visual loss worldwide, particularly in Asia, and the appropriate understanding of the structures in PCV previously described as polypoidal lesions is important for understanding their pathogenesis, diagnosis, and prognosis. Objective To report the morphologic characteristics of polypoidal lesions and their association with branching vascular networks (BVNs) in eyes with PCV using swept-source optical coherence tomographic angiography (SS-OCTA). Design, Setting, and ...
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Influence of Axial Length on Parafoveal and Peripapillary Metrics from Swept Source Optical Coherence Tomography Angiography.
Purpose : To assess the effect of axial length (AL) on the quantification of superficial vessel density of both macular and disc region using swept source optical coherence tomography angiography (SSOCTA). Methods : This is a cross-sectional clinical study. Seventy-five eyes from 75 Chinese healthy participants (56 females) with a mean age of 26.66.8 (range 19-50) years were included in this study. All eyes were imaged with SSOCTA, using a ...
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Shanghai Jiao Tong University
Automatic Choroid Layer Segmentation from Optical Coherence Tomography Images Using Deep Learning
The choroid layer is a vascular layer in human retina and its main function is to provide oxygen and support to the retina. Various studies have shown that the thickness of the choroid layer is correlated with the diagnosis of several ophthalmic diseases. For example, diabetic macular edema (DME) is a leading cause of vision loss in patients with diabetes. Despite contemporary advances, automatic segmentation of the choroid layer remains ...
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Shanghai Jiao Tong University
Robust deep learning method for choroidal vessel segmentation on swept source optical coherence tomography images
Accurate choroidal vessel segmentation with swept-source optical coherence tomography (SS-OCT) images provide unprecedented quantitative analysis towards the understanding of choroid-related diseases. Motivated by the leading segmentation performance in medical images from the use of deep learning methods, in this study, we proposed the adoption of a deep learning method, RefineNet, to segment the choroidal vessels from SS-OCT images. We quantitatively evaluated the RefineNet on 40 SS-OCT images consisting of ~3 ...
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High-performance optical coherence velocimeter: theory and applications
We proposed a high-performance optical coherence velocimeter (OCV) based on broadband optical interference which achieves spatial resolution from interference cancellation or enhancement of different components of the broadband light. There is a challengeable issue for OCV that the interference fringes become blurred when the velocity of detected object is relatively large, hindering the pace of OCV application in high-velocity field. To resolve this, the relationship between blurry coefficient and OCV ...
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The safety of renal denervation as assessed by optical coherence tomography: pre- and post-procedure comparison with multi-electrode ablation catheter in animal experiment
Objective Prove the effectiveness and safety of multi-electrode ablation catheter in renal denervation (RDN) by optical coherence tomography (OCT). Methods 16 renal arteries were enrolled from 8 pigs. Angiography and OCT were used to obtain the morphology changes before RDN and 1-month follow-up. Blood pressure and creatinine were tested to prove the effectiveness and safety of the catheter. Results 1 renal artery was excluded because of the small diameter. 15 ...
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Dynamic Optical Coherence Tomography Is a New Technique for Imaging Skin Around Lower Extremity Wounds
Chronic wounds such as venous leg ulcers invariably heal slowly and recur. In the case of venous leg ulcers, poor healing of chronic wounds is variously attributed to ambulatory hypertension, impaired perfusion and diffusion, presence of chronic inflammation at wound sites, lipodermatosclerosis, and senescence. The aim of this study was to investigate whether a new technique, optical coherence tomography (OCT), which permits imaging of blood capillaries in the peri-wound skin ...
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Faster 3-D imaging could aid diagnosis of cardiovascular, gastrointestinal disease
...ificant amounts of imaging data they require limits imaging speed," said research team leader, Jigang Wu from Shanghai Jiao Tong University. "Our new method solves this problem by forming 3-D images from much less data."...
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Three-dimensional endoscopic OCT using sparse sampling with a miniature magnetic-driven scanning probe
We propose to apply sparse sampling and compressive sensing (CS) reconstruction in three-dimensional (3D) endoscopic optical coherence tomography (OCT) to reduce the amount of data required in the imaging process. We used a homemade miniature side-imaging magnetic-driven scanning probe with an outer diameter of 1.4 mm in a 1310 nm swept-source OCT system to acquire two-dimensional (2D) circumferential cross-sectional images of an ex vivo pigeon trachea sample. 3D imaging ...
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Assessing the biomechanical properties of the porcine crystalline lens as a function of intraocular pressure with optical coherence elastography
In this study, we investigated the relationship between the biomechanical properties of the crystalline lens and intraocular pressure (IOP) using a confocal acoustic radiation force (ARF) and phase-sensitive optical coherence elastography (OCE) system. ARF induced a small displacement at the apex of porcine lenses in situ at various artificially controlled IOPs. Maximum displacement, relaxation rate, and Youngs modulus were utilized to assess the stiffness of the crystalline lens. The results ...
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First Presentation of Integration of Intravascular Optical Coherence Tomography and Computational Fractional Flow Reserve
Observation of anterior chamber volume after cataract surgery with swept-source optical coherence tomography
Purpose To investigate the changes in the anterior chamber volume (ACV) with swept-source optical coherence tomography (SS-OCT) after cataract surgery and the factors that influence these ACV changes. Methods This was a prospective cohort study. Fifty-one patients who underwent cataract surgery were enrolled. Their ACV, anterior chamber depth, and angle widths were measured with SS-OCT before and 1 day, 1 week, and 1 month after surgery. The associations between the ...
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About Shanghai Jiao Tong University
Shanghai Jiao Tong University sometimes referred to as Shanghai Jiaotong University or Jiaotong University, is a top public research university located in Shanghai, renowned as one of the oldest and most prestigious selective universities in China. It is a member of the C9 League in China