1. Seoul National University

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    1. Mentioned In 99 Articles

    2. Parapapillary Choroidal Microvasculature Dropout in Glaucoma A Comparison between Optical Coherence Tomography Angiography and Indocyanine Green Angiography

      Parapapillary Choroidal Microvasculature Dropout in Glaucoma  A Comparison between Optical Coherence Tomography Angiography and Indocyanine Green Angiography
      Purpose To investigate whether the parapapillary choroidal microvasculature dropout (MvD) determined by optical coherence tomography angiography (OCTA) in glaucomatous eyes indicates a true perfusion defect and whether the MvD accurately represents the area of nonperfusion. Design Observational case series. Participants Thirty primary open-angle glaucoma (POAG) patients with choroidal MvD as determined by OCTA and 13 POAG patients without this dropout. Methods Peripapillary circulation was evaluated using both OCTA and indocyanine ...
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    3. Diagnostic Ability of Wide-field Retinal Nerve Fiber Layer Maps Using Swept-Source Optical Coherence Tomography for Detection of Preperimetric and Early Perimetric Glaucoma

      Diagnostic Ability of Wide-field Retinal Nerve Fiber Layer Maps Using Swept-Source Optical Coherence Tomography for Detection of Preperimetric and Early Perimetric Glaucoma
      Methods: One hundred eighty-four eyes, including 67 healthy eyes, 43 eyes with PPG, and 74 eyes with EG, were analyzed. Patients underwent a comprehensive ocular examination including red-free RNFL photography, visual field testing and wide-field SS-OCT scanning (DRI-OCT-1 Atlantis; Topcon, Tokyo, Japan). SS-OCT provides a wide-field RNFL thickness map and a SuperPixel map, which are composed of the RNFL deviation map of the peripapillary area and the deviation map of ...
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    4. Underlying Microstructure of Parapapillary Deep-Layer Capillary Dropout Identified by Optical Coherence Tomography Angiography

      Underlying Microstructure of Parapapillary Deep-Layer Capillary Dropout Identified by Optical Coherence Tomography Angiography
      Purpose : To characterize the microstructure underlying the parapapillary deep-layer microvasculature dropout (MvD) identified by optical coherence tomography (OCT) angiography (OCTA) in eyes with primary open-angle glaucoma (POAG). Methods : Parapapillary MvD was defined as a focal sectoral capillary dropout without any visible microvascular network identified in deep-layer en face images obtained using swept-source OCTA. The peripapillary microstructure was characterized in 188 POAG patients with MvD in the parapapillary deep layer. Twelve ...
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    5. Improved accuracy in periodontal pocket depth measurement using optical coherence tomography

      Improved accuracy in periodontal pocket depth measurement using optical coherence tomography
      Purpose The purpose of this study was to examine whether periodontal pocket could be satisfactorily visualized by optical coherence tomography (OCT) and to suggest quantitative methods for measuring periodontal pocket depth. Methods We acquired OCT images of periodontal pockets in a porcine model and determined the actual axial resolution for measuring the exact periodontal pocket depth using a calibration method. Quantitative measurements of periodontal pockets were performed by real axial ...
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    6. Study on application to the field of dentistry using optical coherence tomography (OCT)

      Study on application to the field of dentistry using optical coherence tomography (OCT)
      Purpose This paper describes the basic principles and the feasibility of the field of dental diagnosis of optical coherence tomography (OCT) used in diverse field of medical diagnosis. Materials and methods In this review, the research data of OCT were searched from PubMed, medical journal and related papers. Results Generally, OCT is non-invasive and is possible to secure an excellent spatial resolution and real-time images of biological microstructure. Conclusion This ...
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    7. Thrombus and Plaque Erosion Characterized by Optical Coherence Tomography in Patients With Vasospastic Angin

      Thrombus and Plaque Erosion Characterized by Optical Coherence Tomography in Patients With Vasospastic Angin
      Introduction and objectives Vasospastic angina (VSA) can result in endothelial damage and thrombus formation. The aim of this study was to evaluate the incidence of thrombus and plaque characteristics at coronary spasm segments compared with nonspasm segments by using optical coherence tomography (OCT) in patients with suspected VSA. Methods One hundred and eighty-three patients with suspected VSA were enrolled in this study. The ergonovine provocation test was performed in all ...
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    8. Glaucoma Diagnostic Ability of Layer-by-Layer Segmented Ganglion Cell Complex by Spectral-Domain Optical Coherence Tomography

      Glaucoma Diagnostic Ability of Layer-by-Layer Segmented Ganglion Cell Complex by Spectral-Domain Optical Coherence Tomography
      Purpose : To evaluate the diagnostic ability of layer-by-layer segmented macular ganglion cell complex (GCC) using spectral-domain optical coherence tomography (OCT) for detection of glaucoma and to analyze the topographic patterns of the segmented thicknesses in open-angle glaucoma. Methods : Seventy-seven open-angle glaucoma patients and 59 healthy subjects were enrolled in this cross-sectional study. Spectral-domain OCT with automated segmentation was used to measure the separate thicknesses of macular retinal nerve fiber layer ...
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    9. Spectral-domain optical coherence tomography in manifest glaucoma: its additive role in structural diagnosis

      Spectral-domain optical coherence tomography in manifest glaucoma: its additive role in structural diagnosis
      Purpose To investigate the additive role of spectral-domain optical coherence tomography (SD-OCT) in the structural diagnosis in glaucoma. Design Reliability and validity analysis. Methods Structural examinations from 109 eyes of 109 healthy individuals and 151 eyes of 151 glaucoma patients with different severities were included. Four structural-diagnostic examination sets were prepared using stereo optic disc photography (SDP), red-free retinal nerve fiber layer photography (RNFLP), and SD-OCT: (1) SDP (S), (2 ...
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    10. Imaging Laser-Induced Choroidal Neovascularization in the Rodent Retina Using Optical Coherence Tomography Angiography

      Imaging Laser-Induced Choroidal Neovascularization in the Rodent Retina Using Optical Coherence Tomography Angiography
      Purpose : The purpose of this study was to evaluate the performance of optical coherence tomography angiography (OCTA) in visualizing laser-induced choroidal neovascularization (CNV) in the rodent retina. Methods : Choroidal neovascularization was induced via laser photocoagulation in 2 male Brown Norway rats and 2 male C57BL/6 mice. For qualitative comparison, the animals were imaged in vivo with OCTA, indocyanine green angiography (ICGA), and fluorescein angiography (FA), and ex vivo with ...
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    11. Assessment of Open-Angle Glaucoma Peripapillary and Macular Choroidal Thickness Using Swept-Source Optical Coherence Tomography (SS-OCT)

      Assessment of Open-Angle Glaucoma Peripapillary and Macular Choroidal Thickness Using Swept-Source Optical Coherence Tomography (SS-OCT)
      Objective To compare peripapillary and macular choroidal thickness (PCT and MCT) between open-angle glaucoma (OAG) and normal controls using swept-source optical coherence tomography (SS-OCT), and to evaluate global and localized relationships between choroidal thickness and various factors in OAG, also using SS-OCT. Methods In this cross-sectional comparative study, 134 OAG patients and 73 normal controls were examined. PCT (global, 12 clock-hour sectors), MCT (global, six sectors) were measured by SS-OCT ...
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    12. Estimation of the flow resistances exerted in coronary arteries using a vessel length-based method

      Estimation of the flow resistances exerted in coronary arteries using a vessel length-based method
      Flow resistances exerted in the coronary arteries are the key parameters for the image-based computer simulation of coronary hemodynamics. The resistances depend on the anatomical characteristics of the coronary system. A simple and reliable estimation of the resistances is a compulsory procedure to compute the fractional flow reserve (FFR) of stenosed coronary arteries, an important clinical index of coronary artery disease. The cardiac muscle volume reconstructed from computed tomography (CT ...
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    13. Retinal Nerve Fiber Layer Thickness Measurement Comparison Using Spectral Domain and Swept Source Optical Coherence Tomography

      Retinal Nerve Fiber Layer Thickness Measurement Comparison Using Spectral Domain and Swept Source Optical Coherence Tomography
      Purpose To investigate the retinal nerve fiber layer (RNFL) thickness concordance when measured by spectral domain (SD) and swept source (SS) optical coherence tomography (OCT), and to compare glaucoma-discriminating capability. Methods RNFL thicknesses were measured with the scan circle, centered on the optic nerve head, in 55 healthy, 41 glaucoma suspected, and 87 glaucomatous eyes. The RNFL thickness measured by the SD-OCT (sdRNFL thickness) and SS-OCT (ssRNFL thickness) were compared ...
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    14. Early Retinal Changes in Hunter Syndrome According to Spectral Domain Optical Coherence Tomography

      Early Retinal Changes in Hunter Syndrome According to Spectral Domain Optical Coherence Tomography
      Dear Editor, Mucopolysaccharidosis is an inheritable storage disease with deficiency of lysosomal enzymes that degrade glycosaminoglycans [ 1 ]. Mucopolysaccharidosis type II, also known as Hunter syndrome, is an X-linked inherited deficiency of enzyme iduronate 2-sulfatase, resulting in progressive accumulation of dermatan sulfate and heparin sulfate [ 1 ]. In many mucopolysaccharidoses, glycosaminoglycans accumulate in the retinal pigment epithelial (RPE) cells, resulting in pronounced lysosomal distension [ 2 ]. Previous studies have revealed outer nuclear layer ...
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    15. Microperimetry and spectral domain optical coherence tomography in myelinated retinal nerve fibers

      Microperimetry and spectral domain optical coherence tomography in myelinated retinal nerve fibers
      Dear Sir, I write to present the correlation between microperimetric (MP) values and the density of myelinated retinal nerve fibers (MNFs) in optical coherence tomography (OCT) imaging. MNFs appear as white or gray-white striated patches that correspond in shape to the distribution of retinal nerve fibers and demonstrate frayed borders[1] . Visual system myelination normally begins at the optic tracts at 7mo of gestational age and progresses anteriorly, finishing within ...
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  2. About Seoul National University

    Seoul National University

    Seoul National University is a public research university located in Seoul, Republic of Korea, ranked 50th in the world and 8th in Asia by US News and World Report, and 24th in the world in publications by the Science Citation Index Founded in 1946, Seoul National University was the first national university in South Korea, and served as a model for the many national and public universities in the country. Seoul National University has been recognized for its leading role in Korean academia. 

    Seoul National University Hospital is located in Gumi-dong, Bundang, Seongnam, Gyeonggi-do, South Korea. It began its first treatment on 10 May 2003. It was set up due to a rapid increase in demand for geriatric treatment and the government's request for the establishment of a medical facility for local residents. Seoul National University Bundang Hospital, consists of 6 departments : the Geriatric Medical Centre, Heart Centre, Cranial nerve Centre, Lung Centre, Articulation Centre, and the Health Improvement Centre, and 23 departments, such as Internal Medicine, Surgery, Chest Surgery, Neurosurgery, Orthopaedics, Plastic Surgery, Obstetrics and Gynaecology, and Pediatrics. There is also an accident and emergency department.