1. Semmelweis University

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    1. Mentioned In 43 Articles

    2. Influence of Posterior Subcapsular Cataract on Structural OCT and OCT Angiography Vessel Density Measurements in the Peripapillary Retina

      Influence of Posterior Subcapsular Cataract on Structural OCT and OCT Angiography Vessel Density Measurements in the Peripapillary Retina
      Purpose: To investigate the influence of posterior subcapsular cataract (PSC) on structural optical coherence tomography (OCT) and OCT angiography vessel density (VD) measurements. Methods: One eye each of 10 consecutive participants with PSC were imaged using the Angiovue/RTvue-XR OCT via undilated pupil, and 30 minutes later via dilated pupil. Peripapillary retinal nerve fiber layer thickness (RNFLT), peripapillary capillaries and all-vessels VD, ganglion cell complex thickness (GCC), parafoveal VD and ...
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    3. Semi-manual Vessel Density Analysis on Optical Coherence Tomography Angiography Images of Healthy Adults

      Semi-manual Vessel Density Analysis on Optical Coherence Tomography Angiography Images of Healthy Adults
      Optical coherence tomography angiography (OCTA) is a software upgrade on conventional spectral-domain or swept-source optical coherence tomography devices that enables non-invasive, dye-free, three dimensional analysis of the retinal vessels. Vessel density is a very important parameter almost in all retinal disorders. In the recent past, automated quantification software was built into some OCTA devices which can automatically calculate the retinal vessel density as well. In this study two semi-manual techniques ...
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    4. Valsalva Maneuver and Peripapillary OCT Angiography Vessel Density

      Valsalva Maneuver and Peripapillary OCT Angiography Vessel Density
      Purpose: To investigate the potential influence of breath holding on the results of peripapillary vessel density (VD) measurement with optical coherence tomography angiography. Materials and Methods: Three peripapillary VD measurements were made at 2-minute intervals on the right eye of 12 healthy young volunteers using the Angiovue/RTvue-XR OCT (software version 2017.1, Phase 7 update) without changing the head and body positions. During the first 2 measurements the volunteers ...
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    5. Choroidal thickness changes in non-treated eyes of patients with diabetes: swept-source optical coherence tomography study

      Choroidal thickness changes in non-treated eyes of patients with diabetes: swept-source optical coherence tomography study
      Aims To measure choroidal thickness (CT) in diabetic eyes and its correlation with metabolic status and the severity of diabetic retinopathy (DR). Materials and methods Prospective cross-sectional study using swept-source optical coherence tomography. CT maps of 96 treatment nave eyes of 48 patients with diabetes were compared to 46 eyes of 23 healthy controls. CT changes and their relation to diabetes, age, gender, disease duration, hypertension (HT), hemoglobin A1c level ...
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    6. The Use of Optical Coherence Tomography for the Detection of Early Diabetic Retinopathy

      The Use of Optical Coherence Tomography for the Detection of Early Diabetic Retinopathy
      Diabetic retinopathy (DR) is one of the leading causes of vision loss globally with a severe burden on all societies due to its high treatment and rehabilitation costs. The early diagnosis of DR may provide preventive steps (including retinal laser therapy and tight carbohydrate, blood pressure, and cholesterol control) that could in turn help to avoid progression of the pathology with the resultant vision loss. Optical coherence tomography (OCT) enables ...
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    7. Comparison of Peripapillary OCT Angiography Vessel Density and Retinal Nerve Fiber Layer Thickness Measurements for Their Ability to Detect Progression in Glaucoma

      Comparison of Peripapillary OCT Angiography Vessel Density and Retinal Nerve Fiber Layer Thickness Measurements for Their Ability to Detect Progression in Glaucoma
      Purpose: The aim of this study was to investigate the applicability of peripapillary optical coherence tomography angiography angioflow vessel density measurements in the retinal nerve fiber layer for the detection of glaucomatous progression and to compare its performance with that of retinal nerve fiber layer thickness (RNFLT) measurements. Methods: Prospective RNFLT and vessel density measurements with the same Angiovue/RTVue-XR instrument were made immediately one after another on 1 eye ...
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    8. Optical Coherence Tomography Angiography Examinations in Chronic Retinal Artery Occlusion (RAO-OCTA)

      Optical Coherence Tomography Angiography Examinations in Chronic Retinal Artery Occlusion (RAO-OCTA)
      Occlusion of the retinal arteries is an emergency which causes sudden, painless unilateral vision loss. Loss of blood flow causes ischemic damage to the retina. The extent of damage depends on the area affected. Following the acute phase of the disease re-canalization occurs and lesser blood flow can be detected usually without functional recovery. Purpose of the study is to examine the retinal blood flow in chronic cases of retinal ...
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    9. Optical Coherence Tomography Angiography to Better understand Glaucoma

      Optical Coherence Tomography Angiography to Better understand Glaucoma
      The term optical coherence tomography angiography (OCTA) comprises different OCT-based technologies which all allow noninvasive assessment of retinal perfusion, based on moving red blood cells. The main areas where OCTA is currently used are investigation of perfusion and vascular structure of the macular retina (e.g., in macular degenerations and diabetic macular diseases) and the disk and peripapillary retina (in glaucoma and other optic disk diseases). The current editorial provides ...
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    10. Relationship Between OCT Angiography Temporal Peripapillary Vessel-Density and Octopus Perimeter Paracentral Cluster Mean Defect

      Relationship Between OCT Angiography Temporal Peripapillary Vessel-Density and Octopus Perimeter Paracentral Cluster Mean Defect
      Purpose of the Study: The purpose of the study was to investigate the relationship between optical coherence tomography angiography angioflow vessel-density (PAFD) measured in the retinal nerve fiber layer in the temporal peripapillary sector and the average of the spatially corresponding superior and inferior paracentral cluster mean defect values (mean paracentral MD) measured with Octopus perimetry. Materials and Methods: Spaermans correlation between temporal peripapillary PAFD acquired with the Angiovue OCT ...
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    11. Two-dimensional fractal analysis of retinal tissue of healthy and diabetic eyes with optical coherence tomography

      Two-dimensional fractal analysis of retinal tissue of healthy and diabetic eyes with optical coherence tomography
      In the ophthalmic research, the measurement of the retinal thickness is usually employed for characterizing the structural changes of the retinal tissue. However, changes in the fractal dimension (FD) may provide additional information regarding the structure of the retinal layers and their early damage in ocular diseases. In the present paper, we investigated the possibility of detecting changes in the structure of the cellular layers of the retina by applying ...
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    12. Evaluation of Retinal Nerve Fiber Layer Thickness and Ganglion Cell Complex Progression Rates in Healthy, Ocular Hypertensive, and Glaucoma Eyes With the Avanti RTVue-XR Optical Coherence Tomograph Based on 5-Year Follow-up

      Evaluation of Retinal Nerve Fiber Layer Thickness and Ganglion Cell Complex Progression Rates in Healthy, Ocular Hypertensive, and Glaucoma Eyes With the Avanti RTVue-XR Optical Coherence Tomograph Based on 5-Year Follow-up
      Purpose: To determine retinal nerve fiber layer thickness (RNFLT) and ganglion cell complex (GCC) progression rates for healthy eyes and undertreatment ocular hypertensive (OHT) and glaucoma eyes with the Avanti RTVue-XR optical coherence tomography. Materials and Methods: Seventeen healthy subjects (34 eyes), 17 medically treated OHT patients (34 eyes), and 67 medically treated glaucoma patients (122 eyes) were imaged prospectively at 6-month intervals (median follow-up 5.3 y, 11 visits ...
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    13. Influence of myelinated retinal nerve fibers on retinal vessel density measurement with AngioVue OCT angiography

      Influence of myelinated retinal nerve fibers on retinal vessel density measurement with AngioVue OCT angiography
      Myelinated retinal nerve fibers (MRNF) represent an asymptomatic developmental anomaly in which myelin sheaths extend to a group of retinal nerve fibers along their intraocular portion. The additional volume of the myelin sheaths causes displacement of the axons toward the vitreous body. We investigated the effect of localized MRNF on peripapillary vessel density measurement results using optical coherence tomography (OCT) angiography. Peripapillary angioflow density measurements (PAFD, % of the analyzed retinal ...
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    14. Vessel density calculated from OCT angiography in 3 peripapillary sectors in normal, ocular hypertensive, and glaucoma eyes

      Vessel density calculated from OCT angiography in 3 peripapillary sectors in normal, ocular hypertensive, and glaucoma eyes
      Disturbed peripapillary microcirculation may have a role in the development of glaucoma. Recently, using noninvasive optical coherence tomography (OCT) angiography with the AngioVue OCT (Optovue Inc., Fremont, CA, USA), reduced peripapillary vessel density was found in glaucoma. In this case series, we investigate the relationship between retinal nerve fiber layer (RNFL) damage and peripapillary angioflow density (PAFD, % of the analyzed retinal area) in the superotemporal (ST), inferotemporal (IT), and temporal ...
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  2. About Semmelweis University

    Semmelweis University

    Semmelweis University was founded in 1769 and is the oldest medical school in Hungary. The faculty became an independent medical school after the Second World War and developed into a university that teaches medicine, dentistry, pharmacy, health sciences, health management, and physical education and sport sciences.  The University is named after Ignác Semmelweis (1818-1865), the revolutionary obstetrician who discovered the cause of puerperal fever in the 1840s, and is therefore also known as “the savior of mothers”.   Today, Semmelweis University is widely recognized as one of Europe’s leading centers of medicine and health sciences, combining innovation and a time-tested tradition in three main areas: education, research and health care.