1. Sebastien Vergnole

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    1. Mentioned In 21 Articles

    2. Intravascular optical coherence tomography to characterize tissue deformation during angioplasty: preliminary experiments with artery phantoms

      Intravascular optical coherence tomography to characterize tissue deformation during angioplasty: preliminary experiments with artery phantoms
      We explored the potential of intravascular optical coherence tomography (IVOCT) to assess deformation during angioplasty balloon inflation. Using a semi-compliant balloon and artery phantoms, we considered two experimental scenarios. The goal for the first scenario was to investigate if variation in the elasticity of the structure surrounding the balloon could be sensed by IVOCT monitoring. In this scenario, we used three single-layer phantoms with various mechanical properties. Image analysis was ...
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    3. Optimal signal processing of nonlinearity in swept-source and spectral-domain optical coherence tomography

      Optimal signal processing of nonlinearity in swept-source and spectral-domain optical coherence tomography
      We demonstrate the efficiency of the convolution using an optimized Kaiser–Bessel window to resample nonlinear data in wavenumber for Fourier-domain optical coherence tomography (OCT). We extend our previous experimental demonstration that was performed with a specific swept-source nonlinearity. The method is now applied to swept-source OCT data obtained for various simulated swept-source nonlinearities as well as spectral-domain OCT data obtained from both simulations and experiments. Results show that the ...
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    4. Real-time Control of Angioplasty Balloon Inflation Based on Feedback from Intravascular Optical Coherence Tomography: Experimental Validation on an Excised Heart and a Beating Heart Model

      Real-time Control of Angioplasty Balloon Inflation Based on Feedback from Intravascular Optical Coherence Tomography: Experimental Validation on an Excised Heart and a Beating Heart Model
      We report on real-time control of balloon inflation inside porcine arteries. In a first step, experiments were done in a coronary artery of an excised heart. In a second step, experiments were done in a beating heart setup providing conditions very close to in vivo conditions without the complications. A programmable syringe pump was used to inflate a compliant balloon in arteries, while intravascular optical coherence tomography (IVOCT) monitoring was ...
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    5. Real-time Control of Angioplasty Balloon Inflation Based on Feedback from Intravascular Optical Coherence Tomography: Preliminary Study on an Artery Phantom

      Real-time Control of Angioplasty Balloon Inflation Based on Feedback from Intravascular Optical Coherence Tomography: Preliminary Study on an Artery Phantom
      A method is proposed to achieve computerized control of angioplasty balloon inflation, based on feedback from intravascular optical coherence tomography (IVOCT). Controlled balloon inflation could benefit clinical applications, cardiovascular research, and medical device industry. The proposed method was experimentally tested for balloon inflation within an artery phantom. During balloon inflation, luminal contour of the phantom was extracted from IVOCT images in real-time. Luminal diameter was estimated from the obtained contour ...
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    6. Detection of inflating balloon in optical coherence tomography images of a porcine artery in a beating heart experiment

      Detection of inflating balloon in optical coherence tomography images of a porcine artery in a beating heart experiment
      Suboptimal results of angioplasty procedures have been correlated to arterial damage during balloon inflation. We propose to monitor balloon inflation during the angioplasty procedure by detecting the balloon contours with intravascular optical coherence tomography (IVOCT). This will shed more light on the interaction between the balloon and the artery and to assess the artery's mechanical response. An automatic edge detection algorithm is applied for detection of the outer surface ...
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    7. Optical coherence tomography layer thickness characterization of a mock artery during angioplasty balloon deployment

      Optical coherence tomography layer thickness characterization of a mock artery during angioplasty balloon deployment
      Optical coherence tomography (OCT) is used to study the deformation of a mock artery in an angioplasty simulation setup. An OCT probe integrated in a balloon catheter provides intraluminal real-time images during balloon inflation. Swept-source OCT is used for imaging. A 4 mm semi-compliant polyurethane balloon is used for experiments. The balloon is inflated inside a custom-built multi-layer artery phantom. The phantom has three layers to mock artery layers, namely ...
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    8. Tailoring wavelength sweep for SS-OCT with a programmable picosecond laser

      Tailoring wavelength sweep for SS-OCT with a programmable picosecond laser
      This paper presents a unique and novel picosecond laser source that offers complete tailoring of the wavelength sweep and that benefits swept-source optical coherence tomography (SS-OCT) applications. Along with the advantages of a fiber-based architecture, the source is a fully programmable, electronically controlled actively mode-locked laser capable of rapidly tuning the wavelength and pulse characteristics. Furthermore, several sweep modes and configurations are available which can be defined by range, with ...
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    9. Feature Of The Week 9/12/10: Intravascular Optical Coherence Tomography Studies on an Excised Beating Heart – a New Model and an Amazing Video

      Feature Of The Week 9/12/10: Intravascular Optical Coherence Tomography Studies on an Excised Beating Heart – a New Model and an Amazing Video
      ...optical coherence tomography technology.For more information see recent Article. Courtesy of Guy Lamouche and Sebastien Vergnole. Feature Of The Week 9/12/10: This week we have another very impressive presentation from D...
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    10. Optical Coherence Tomography in Canada One-Day Symposium September 28, 2010

      Optical Coherence Tomography in Canada One-Day Symposium September 28, 2010
      The Industrial Materials Institute (IMI) organizes a one-day symposium on Optical Coherence Tomography (OCT) on Tuesday September 28, 2010, at Université Laval (Quebec City). The goals of the symposium are to increase networking between research groups and to provide interested parties an overview of the current status of OCT research in Canada.
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    11. Angioplasty Video: New Imaging Technique Improves Angioplasty (Video)

      Angioplasty Video: New Imaging Technique Improves Angioplasty (Video)
      From Maryland - Advances in imaging may greatly enhance angioplasty, according to a report published in Review of Scientific Instruments. Researchers added optical coherence tomography to the baloon tipped catheter normally inserted into the arteries to flatten plaque and improve blood flow, thereby making it possible to monitor the inflation of the balloon itself.
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    12. Intravascular optical coherence tomography on a beating heart model

      Intravascular optical coherence tomography on a beating heart model
      The advantages and limitations of using a beating heart model in the development of intravascular optical coherence tomography are discussed. The model fills the gap between bench experiments, performed on phantoms and excised arteries, and whole animal in-vivo preparations. The beating heart model is stable for many hours, allowing for extended measurement times and multiple imaging sessions under in-vivo conditions without the complications of maintaining whole-animal preparation. The perfusate supplying ...
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    13. 1-15 of 21 1 2 »
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  2. About Sebastien Vergnole

    Sebastien Vergnole

    Sébastien Vergnole received an engineering school diploma in Physics from “Centrale Marseille” (France) in 2001, the M.S. and Ph.D. degrees in Physics from the University of Limoges (France) in 2002 and 2005. At that time, he was with the Photonics team of the XLIM laboratory and his research interest was stellar interferometry: particularly, he worked on the potential of using photonics crystal fibers in this field and on the instrumental part of the `OHANA project. Characterization of the chromatic dispersion was one of the main aspects of his studies. From 2005 to April 2011, he was a research associate with the Industrial Materials Institute of the National Research Council of Canada in Boucherville (Québec, Canada). His main field of research was optical coherence tomography (OCT) and more specially Fourier domain OCT, the 2nd generation OCT system. He has been involved mainly in instrumentation and signal processing challenges. 

    Since June 2011, he has been project leader with the R&D team of Horiba Scientific (Jobin-Yvon) in Villeneuve d’Ascq (France).