1. Scott E. Fraser

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    1. Mentioned In 34 Articles

    2. In vivo functional imaging of embryonic chick heart using ultrafast 1310nm-band spectral domain optical coherence tomography

      In vivo functional imaging of embryonic chick heart using ultrafast 1310nm-band spectral domain optical coherence tomography
      ...investigation of cardiac development. Optical Methods in Developmental Biology Andrew M. Rollins; Cecilia Lo; Scott E. Fraser San Francisco, California, USA | February 02, 2013 During the cardiac development, the cardiac...
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    3. Changes in strain and blood flow in the outflow tract of chicken embryo hearts observed with spectral domain optical coherence tomography after outflow tract banding

      Changes in strain and blood flow in the outflow tract of chicken embryo hearts observed with spectral domain optical coherence tomography after outflow tract banding
      ...locities through the OFT as expected. Optical Methods in Developmental Biology Andrew M. Rollins; Cecilia Lo; Scott E. Fraser San Francisco, California, USA | February 02, 2013 In this paper, we demonstrated the use of a...
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    4. Enhanced Optical Angiography Using Intensity Contrast And Phase Contrast Imaging Methods

      Enhanced Optical Angiography Using Intensity Contrast And Phase Contrast Imaging Methods
      The methods described herein are methods to ascertain motion contrast within optical coherence tomography data based upon intensity. The methods of the invention use logarithm operation to convert the multiplicative amplitude or intensity fluctuations (speckle) into the additive variations and recovers the motion contrasts by removing the speckle free signals (static regions) through statistical analysis.
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    5. Treatment for eye disorder

      Treatment for eye disorder
      The present invention relates to altering the physical and/or chemical properties of at least part of at least one tissue in the eye. In a specific embodiment, it relates to the treatment of any eye disorder, although in particular embodiments the individual has a thickened Bruch's membrane. An activating energy source is utilized to effect a controlled diffusion enhancement and/or degradation of Bruch's membrane that enables ...
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    6. In Vivo Human Choroidal Vascular Pattern Visualization Using High-Speed Swept-Source Optical Coherence Tomography at 1060 nm

      In Vivo Human Choroidal Vascular Pattern Visualization Using High-Speed Swept-Source Optical Coherence Tomography at 1060 nm
      Purpose. To investigate the retinal and choroidal vascular pattern, structure, and thickness using high-speed, high axial resolution, swept-source optical coherence tomography (SS-OCT) at 1060 nm, demonstrating enhanced penetration through all choroidal layers. Methods. An ophthalmic SS-OCT system was developed operating at 57,000 A-lines/s with 5.9 μm axial resolution and was used to collect 3D images with scanning angles up to ~70° x 35°. The similar features were ...
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    7. Differential phase-contrast, swept-source optical coherence tomography at 1060 nm for in vivo human retinal and choroidal vasculature visualization

      Differential phase-contrast, swept-source optical coherence tomography at 1060 nm for in vivo human retinal and choroidal vasculature visualization
      Human retinal and choroidal vasculature was visualized by a differential phase-contrast (DPC) method using high-speed, swept-source optical coherence tomography (SS-OCT) at 1060 nm. The vasculature was recognized as regions of motion by creating differential phase-variance (DPV) tomograms: multiple B-scans of individual slices through the retina were collected and the variance of the phase differences was calculated. DPV captured the small vessels and the meshwork of capillaries associated with the inner ...
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    8. Logarithmic intensity and speckle-based motion contrast methods for human retinal vasculature visualization using swept source optical coherence tomography

      Logarithmic intensity and speckle-based motion contrast methods for human retinal vasculature visualization using swept source optical coherence tomography
      ...man retinal vasculature visualization using swept source optical coherence tomography Reza Motaghiannezam and Scott Fraser Biomedical Optics Express, Vol. 3, Issue 3, pp. 503-521 (2012) http://dx.doi.org/10.1364/BOE.3.00...
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    9. Differential intensity contrast swept source optical coherence tomography for human retinal vasculature visualization

      Differential intensity contrast swept source optical coherence tomography for human retinal vasculature visualization
      We demonstrate an intensity-based motion sensitive method, called differential logarithmic intensity variance (DLOGIV), for 3D microvasculature imaging and foveal avascular zone (FAZ) visualization in the in vivo human retina using swept source optical coherence tomography (SS-OCT) at 1060 nm. A motion sensitive SS-OCT system was developed operating at 50,000 A-lines/s with 5.9 μm axial resolution, and used to collect 3D images over 4 mm2 in a normal ...
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    10. Visualization of human retinal capillary networks: a comparison of intensity, speckle-variance and phase-variance optical coherence tomography

      Visualization of human retinal capillary networks: a comparison of intensity, speckle-variance and phase-variance optical coherence tomography
      ...CT techniques and fluorescein angiography (FA). Dae Yu Kim, Jeff Fingler, John S. Werner, Daniel M. Schwartz, Scott E. Fraser and Robert J. Zawadzki, "Visualization of human retinal capillary networks: a comparison of in...
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    11. In vivo human retinal and choroidal vasculature visualization using differential phase contrast swept source optical coherence tomography at 1060 nm

      In vivo human retinal and choroidal vasculature visualization using differential phase contrast swept source optical coherence tomography at 1060 nm
      ...ring the microvasculature and regions of motion through the inner retina and choroid. Reza Motaghiannezam and Scott Fraser, "In vivo human retinal and choroidal vasculature visualization using differential phase contrast...
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    12. Dynamic motion contrast and transverse flow estimation using optical coherence tomography

      Dynamic motion contrast and transverse flow estimation using optical coherence tomography
      The methods described herein are methods to ascertain motion contrast within optical coherence tomography data based upon phase variance. The phase variance contrast observes the nanometer scale motion of scatterers associated with Brownian motion and other non-flow motion. The inventive method of calculating motion contrast from the phase variance can differentiate regions of different mobility based on the motion contrast differences, and can use the phase information to characterize mobility ...
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    13. 16-30 of 34 « 1 2 3 »
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  2. About Scott E. Fraser

    Scott E. Fraser

    Scott E. Fraser is the Anna L. Rosen Professor of Biology and Professor of Bioengineering and Professor of Applied Physics and Director of the Biological Imaging Center at the California Institute of Technology.