1. Sara M. Rey

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    1. Mentioned In 6 Articles

    2. Three- and four-dimensional visualization of cell migration using optical coherence tomography

      Conventionally, cell chemotaxis is studied on two-dimensional (2D) transparent surfaces, due to limitations in optical and image data-collection techniques. However, surfaces that more closely mimic the natural environment of cells are often opaque. Optical coherence tomography (OCT) is a noninvasive label-free imaging technique, which offers the potential to visualize moving cells on opaque surfaces and in three dimensions (3D). Here, we demonstrate that OCT is an effective means of time-lapse ...
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    3. Visualization of 3D cell migration using high speed ultrahigh resolution optical coherence tomography

      Visualization of 3D cell migration using high speed ultrahigh resolution optical coherence tomography
      Using high speed ultrahigh resolution optical coherence tomography (OCT) at 800nm, non-invasive 3D cellular imaging has been accomplished. Cellular resolution imaging on and within these types of substrates is not possible with conventional microscopy techniques such as interference contrast microscopy, and requires the use of fluorescent staining. It is possible to achieve data acquisition rates of 20,000 samples per second with OCT which, in combination with its high axial ...
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  2. About Sara M. Rey

    Sara Rey is with the Biomedical Imaging Group at the School of Optometry and Vision Sciences at Cardiff University.