1. Sapienza University of Rome

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    1. Mentioned In 11 Articles

    2. Choroidal Thinning as a New Finding in Alzheimer's Disease: Evidence from Enhanced Depth Imaging Spectral Domain Optical Coherence Tomography

      Choroidal Thinning as a New Finding in Alzheimer's Disease: Evidence from Enhanced Depth Imaging Spectral Domain Optical Coherence Tomography

      Background: The involvement of retina and its vasculature has been recently described in Alzheimer's disease (AD). However, none of the previous works have yet investigated the choroid in vivo. Objective: Spectral domain optical coherence tomography (SD-OCT) and enhanced depth imaging (EDI) technique is non-invasively used to assess choroidal thickness in patients with AD and to determine whether the peripapillary retinal nerve fiber layer (RNFL) and central retinal thickness are reduced compared to normal subjects. Methods: Forty-two eyes of 21 patients (mean age, 73.1 ± 6.9 years) with a diagnosis of mild to moderate AD and 42 eyes of ...

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    3. Stent-related defects in patients presenting with stent thrombosis: differences at optical coherence tomography between subacute and late/very late thrombosis in the Mechanism Of Stent Thrombosis (MOST) study

      Stent-related defects in patients presenting with stent thrombosis: differences at optical coherence tomography between subacute and late/very late thrombosis in the Mechanism Of Stent Thrombosis (MOST) study

      Aims: Subacute, late, and very late stent thrombosis (ST) may occur after stent implantation, but they are characterised by different underlying pathophysiological mechanisms. We sought to appraise differences between subacute and late/very late ST at the thrombus site by optical coherence tomography (OCT). The Mechanism Of Stent Thrombosis (MOST) study was a prospective multicentre non-randomised registry which enrolled six subacute ST and six controls (subacute ST study), and 17 late/very late ST and 17 controls (late/very late ST study). Methods and results: Patients with subacute ST had a minimum stent area at the thrombus site of 2 ...

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    4. Epiretinal Membranes in Patients with Uveitis: Morphological and Functional Analysis with Spectral Domain Optical Coherence Tomography

      Epiretinal Membranes in Patients with Uveitis: Morphological and Functional Analysis with Spectral Domain Optical Coherence Tomography

      Purpose . To correlate the uveitic epiretinal membrane (ERM) features using spectral-domain optical coherence tomography (SD-OCT) with visual acuity (VA). Methods . Forty-one eyes of 32 patients were included in this retrospective study. SD-OCT was performed in all patients and data were collected at the time of ERM diagnosis and at the final visit. Both best corrected visual acuity (BCVA) and ERM thickness were correlated with the morphological and clinical features. Results . Final BCVA was positively correlated with male sex and the focal pattern of ERM attachment and negatively correlated with IS/OS photoreceptor junction disruption . BVCA change showed a positive correlation ...

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    5. Macular thickness changes evaluated with spectral domain optical coherence tomography after uncomplicated phacoemulsification

      Macular thickness changes evaluated with spectral domain optical coherence tomography after uncomplicated phacoemulsification

      Purpose To determine macular thickness changes after uncomplicated cataract surgery using spectral domain optical coherence tomography (OCT). Methods This was a prospective non-randomized, clinical study. Data were analysed for 40 healthy patients undergoing uneventful phacoemulsification. OCT measurements were performed before surgery and postoperatively at day 1, week 1 and 2, and month 1, 2, 3, and 6. The retinal map was divided into central point thickness (CPT), central 1-mm subfield (CSF), and two peripheral ring areas with diameters of 3 and 6   mm. Fellow eyes were used as controls. Retinal thickness change between the operated and fellow eyes were compared ...

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    6. Transcatheter renal sympathetic ablation for resistant hypertension: in vivo insights in humans from optical coherence tomography

      Transcatheter renal sympathetic ablation for resistant hypertension: in vivo insights in humans from optical coherence tomography
      ..., Italy , * Giuseppe Biondi-Zoccai Affiliations + Department of Medico-Surgical Sciences and Biotechnologies, Sapienza University of Rome, Latina, Italy + Centro per la Lotta contro l'Infarto (CLI) Foundation, Rome, Ital...
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    7. Molecular imaging in atherosclerosis

      Molecular imaging in atherosclerosis

      Atherosclerosis is the major cause of cardiovascular disease, which still has the leading position in morbidity and mortality in the Western world. Many risk factors and pathobiological processes are acting together in the development of atherosclerosis. This leads to different remodelling stages (positive and negative) which are both associated with plaque physiology and clinical presentation. The different remodelling stages of atherosclerosis are explained with their clinical relevance. Recent advances in basic science have established that atherosclerosis is not only a lipid storage disease, but that also inflammation has a fundamental role in all stages of the disease. The molecular events ...

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  2. About Sapienza University of Rome

    Sapienza University of Rome

    Sapienza University of Rome is the largest European university and the most ancient of Rome's three state-funded universities. In Italian , Sapienza means "wisdom" or "knowledge".