1. San Raffaele Scientfic Institute

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    1. Mentioned In 60 Articles

    2. CAPILLARY NETWORK ALTERATIONS IN X-LINKED RETINOSCHISIS IMAGED ON OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY

      CAPILLARY NETWORK ALTERATIONS IN X-LINKED RETINOSCHISIS IMAGED ON OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY
      Purpose: To assess foveal and parafoveal vasculature at the superficial capillary plexus, deep capillary plexus, and choriocapillaris of patients with X-linked retinoschisis by means of optical coherence tomography angiography. Methods: Six patients with X-linked retinoschisis (12 eyes) and seven healthy controls (14 eyes) were recruited and underwent complete ophthalmologic examination, including best-corrected visual acuity, dilated fundoscopy, and 3 3-mm optical coherence tomography angiography macular scans (DRI OCT Triton; Topcon Corp ...
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    3. Acute macular neuroretinopathy: pathogenetic insights from optical coherence tomography angiography

      Acute macular neuroretinopathy: pathogenetic insights from optical coherence tomography angiography
      Aim To describe the optical coherence tomography angiography (OCT-A) features of patients affected by acute macular neuroretinopathy (AMN). Methods This is a prospective, observational, cross-sectional study. Multimodal imaging, including spectral domain OCT (Spectralis HRA+OCT; Heidelberg Engineering, Heidelberg, Germany) and 66mm swept source OCT-A (ZEISS PLEX Elite 9000; ZEISS, Dublin, California), was performed on all patients. The primary outcome measure was assessment of the vascular alterations of the superficial (SCP ...
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    4. Procedural and follow-up insights from optical coherence tomography-guided management of intracoronary stent loss and crushing

      Procedural and follow-up insights from optical coherence tomography-guided management of intracoronary stent loss and crushing
      A 55-year-old man underwent left anterior descending (LAD) chronic total occlusion intervention (Fig. 1A, B). The occlusion was crossed antegradely and predilated (Fig. 1C). During delivery of a 3.0 33-mm stent, the operator encountered significant resistance, and soon noticed stent dislodgment from the delivery system. Since the stent appeared deformed and was located in front of the circumflex and first diagonal (D1) ostia (Fig. 1D), the operator chose to ...
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    5. Retinal Vascular Impairment in Best Vitelliform Macular Dystrophy Assessed by Means of Optical Coherence Tomography Angiography

      Retinal Vascular Impairment in Best Vitelliform Macular Dystrophy Assessed by Means of Optical Coherence Tomography Angiography
      Purpose To evaluate vascular abnormalities at superficial (SCP), deep (DCP) capillary plexuses and choriocapillaris (CC) in patients with Best vitelliform macular dystrophy (BVMD) by means of optical coherence tomography angiography (OCT-A). Design Cross-sectional case series. Methods Sixty-six eyes of 33 patients with BVMD (sixteen males) and 33 controls were consecutively enrolled. Patients were subdivided in classic stages and underwent best-corrected visual acuity (BCVA), fundus autofluorescence and spectral domain-optical coherence tomography ...
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    6. Zero-contrast percutaneous coronary intervention guided by dextran-based optical coherence tomography

      Zero-contrast percutaneous coronary intervention guided by dextran-based optical coherence tomography
      Subjects with advanced chronic kidney disease (CKD) and coronary artery disease are often denied percutaneous coronary intervention (PCI) due to the aversion to the risk of contrast-induced nephropathy. We present the case of a 76-year-old man with stage 4 CKD requiring coronary revascularization. Zero-contrast PCI was successfully performed using dextran-based optical coherence tomography (OCT) guidance. Our report suggests the feasibility of dextran-based OCT-guided zero-contrast PCI in patients with advanced CKD ...
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    7. OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY FEATURES OF ANGIOID STREAKS

      OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY FEATURES OF ANGIOID STREAKS
      Purpose: To analyze the optical coherence tomography angiography features of eyes affected with angioid streaks (AS) and to evaluate their ability to predict choroidal neovascularization (CNV) activity. Methods: Angioid streaks were individuated from a pool of consecutive patients. Eyes with and without CNV were evaluated by multimodal imaging. Results: Thirty-eight eyes of 19 consecutive patients diagnosed with AS were included. Thirty of 38 eyes with CNV and 8 of 38 ...
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    8. Refining Coats’ disease by ultra-widefield imaging and optical coherence tomography angiography

      Refining Coats’ disease by ultra-widefield imaging and optical coherence tomography angiography
      ...nsecutive patients affected by Coats disease were prospectively recruited at the Department of Ophthalmology, San Raffaele Hospital, Milan, Italy in this cross-sectional, observational study. Patients underwent UWF color...
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    9. Optical Coherence Tomography Angiography of Retinal Cavernous Hemangioma

      Optical Coherence Tomography Angiography of Retinal Cavernous Hemangioma
      etinal cavernous hemangioma is a rare, benign, retinal tumor characterized by angiomatous proliferation of vessels within the inner retina or the optic disc.1 Here we report a case of retinal cavernous hemangioma on the margin of the optic disc in the right eye of a 61-year-old asymptomatic female. The lesion was studied with multimodal imaging which included structural optical coherence tomography, fluorescein angiography, blue fundus auto-fluorescence, optical coherence tomography ...
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    10. Effect Of Intravitreal Ranibizumab On Ganglion Cell Complex And Peripapillary Retinal Nerve Fiber Layer In Neovascular AGE-RELATED Macular Degeneration Using Spectral Domain Optical Coherence Tomography

      Effect Of Intravitreal Ranibizumab On Ganglion Cell Complex And Peripapillary Retinal Nerve Fiber Layer In Neovascular AGE-RELATED Macular Degeneration Using Spectral Domain Optical Coherence Tomography
      Purpose: To analyze the changes in ganglion cell complex and peripapillary retinal nerve fiber layer thickness, in central macular thickness and choroidal thickness on spectral domain optical coherence tomography in patients with neovascular age-related macular degeneration treated with intravitreal ranibizumab injections. Methods: All consecutive patients with untreated neovascular age-related macular degeneration received loading phase of three monthly intravitreal ranibizumab, followed by retreatments on a pro re nata protocol for 12 ...
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    11. Optical coherence tomography angiography of the peripapillary retina and optic nerve head in dominant optic atrophy

      Optical coherence tomography angiography of the peripapillary retina and optic nerve head in dominant optic atrophy
      Peripapillar and nerve head vessel density (VD) was measured in 10 patients affected by Dominant optic atrophy (DOA) using optical coherence tomography angiography (OCT-A) and compared to the measurements of 15 age- and gender-matched controls. DOA patients showed VD reduction, mostly in the temporal and inferotemporal peripapillary sectors, according to the preferential involvement of the papillomacular bundle. Despite poor best-corrected visual acuity (BCVA), OCT-A revealed good repeatability. VD correlated with ...
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    12. Optical coherence tomography angiography features of chorioretinal folds: a case series

      Optical coherence tomography angiography features of chorioretinal folds: a case series
      ...ology, and follow-up data of patients referred for chorioretinal folds to the Medical Retina Imaging Unit of San Raffaele Hospital in the period January-March 2016 were collected. Multimodal imaging evaluation, comprehe...
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    13. Optical coherence tomography in Best vitelliform macular dystrophy

      Optical coherence tomography in Best vitelliform macular dystrophy
      To analyze spectral-domain optical coherence tomography (SD-OCT)-specific findings in the different stages of vitelliform macular dystrophy (VMD). Thirty-seven patients were prospectively recruited. All the patients underwent a complete ophthalmologic examination, including best-corrected visual acuity (BCVA), biomicroscopy, and SD-OCT. The examined findings were vitelliform material, neurosensory detachment, intraretinal hyperreflective foci, and the status of external limiting membrane, ellipsoid zone, and retinal pigment epithelium. The primary outcome was the stratification of ...
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  2. About San Raffaele Scientfic Institute

    San Raffaele Scientfic Institute

    San Raffaele Hospital is a private Scientific Institute, belonging to the San Raffaele del Monte Tabor Foundation, recognised by the Italian Ministry of Health as a Scientific Institute carrying out biomedical research and clinical activities of relevant national interest (IRCCS). According to the inspiring principles of its founding Organisation, the mission of the San Raffaele is to cure and assist diseased individuals, following the Gospel proposition: "Go, teach, heal". Such a mission is accomplished by focusing every aspect of the Institute’s activities on Man, viewed as an multifaceted entity endowed with inseparable biological, psychological and spiritual elements