1. Ryerson University

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    1. Mentioned In 92 Articles

    2. Blood flow velocity measurement by endovascular Doppler optical coherence tomography

      Blood flow velocity measurement by endovascular Doppler optical coherence tomography
      Blood flow velocity and volumetric flow measurements are important parameters for assessment of the severity of stenosis and the outcome of interventional therapy. However, feasibility of intravascular flow measurement using a rotational catheter based phase resolved Doppler optical coherence tomography (DOCT) is difficult. Motion artefacts induced by the rotating optical imaging catheter, and the radially dependent noise background of measured Doppler signals are the main challenges encountered. In this study ...
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    3. Development of quantitative parameters to assess in-vivo optical coherence tomography images of late oral radiation toxicity patients

      Development of quantitative parameters to assess in-vivo optical coherence tomography images of late oral radiation toxicity patients
      Late oral radiation toxicity is a common condition occurring in a considerable percentage of head and neck cancer patients after radiation therapy which reduces their quality of life. The current examination of these patients is based on a visual inspection of the surface of the oral cavity; however, it is well known that many of the complications start in the subsurface layers before any superficial manifestation. Considering the currently suboptimal ...
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    4. In vivo feasibility of endovascular Doppler optical coherence tomography

      In vivo feasibility of endovascular Doppler optical coherence tomography
      Feasibility of detecting intravascular flow using a catheter based endovascular optical coherence tomography (OCT) system is demonstrated in a porcine carotid model in vivo. The effects of A-line density, radial distance, signal-to-noise ratio, non-uniform rotational distortion (NURD), phase stability of the swept wavelength laser and interferometer system on Doppler shift detection limit were investigated in stationary and flow phantoms. Techniques for NURD induced phase shift artifact removal were developed by ...
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    5. Intraoperative handheld optical coherence tomography forward-viewing probe: physical performance and preliminary animal imaging

      Intraoperative handheld optical coherence tomography forward-viewing probe: physical performance and preliminary animal imaging
      A prototype intraoperative hand-held optical coherence tomography (OCT) imaging probe was developed to provide micron resolution cross-sectional images of subsurface tissue during open surgery. This new ergonomic probe was designed based on electrostatically driven optical fibers, and packaged into a catheter probe in the form factor of clinically accepted Bayonet shaped neurosurgical probes. Optical properties of the probe were measured to have a ~20 μm spot size, 5 mm working ...
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    6. Hybrid intravascular ultrasound and optical coherence tomography catheter for imaging of coronary atherosclerosis

      Hybrid intravascular ultrasound and optical coherence tomography catheter for imaging of coronary atherosclerosis
      Objective To demonstrate the feasibility of imaging human coronary atherosclerosis using a novel hybrid intravascular ultrasound (IVUS) and optical coherence tomography (OCT) imaging catheter. Background IVUS and OCT have synergistic advantages and recent studies involving both modalities suggest the use of a hybrid imaging catheter may offer improved guidance of coronary interventions and plaque characterization. Methods A 1.3 m custom hybrid IVUS-OCT imaging probe was built within a 4F ...
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    7. Comprehensive data visualization for high resolution endovascular carotid arterial wall imaging

      Comprehensive data visualization for high resolution endovascular carotid arterial wall imaging
      Carotid angioplasty and stenting is a minimally invasive endovascular procedure that may benefit from in vivo high resolution imaging for monitoring the physical placement of the stent and potential complications. The purpose of this pilot study was to evaluate the ability of optical coherence tomography to construct high resolution 2D and 3D images of stenting in porcine carotid artery. Four Yorkshire pigs were anaesthetized and catheterized. A state-of-the-art optical coherence ...
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    8. Feasibility of optical coherence elastography measurements of shear wave propagation in homogeneous tissue equivalent phantoms

      Feasibility of optical coherence elastography measurements of shear wave propagation in homogeneous tissue equivalent phantoms
      In this work, we explored the potential of measuring shear wave propagation using optical coherence elastography (OCE) based on a swept-source optical coherence tomography (OCT) system. Shear waves were generated using a 20 MHz piezoelectric transducer (circular element 8.5 mm diameter) transmitting sine-wave bursts of 400 μs, synchronized with the OCT swept source wavelength sweep. The acoustic radiation force (ARF) was applied to two gelatin phantoms (differing in gelatin ...
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    9. Speckle variance optical coherence tomography of the rodent spinal cord: in vivo feasibility

      Speckle variance optical coherence tomography of the rodent spinal cord: in vivo feasibility
      Optical coherence tomography (OCT) has the combined advantage of high temporal (µsec) and spatial (less than 10µm) resolution. These features make it an attractive tool to study the dynamic relationship between neural activity and the surrounding blood vessels in the spinal cord, a topic that is poorly understood. Here we present work that aims to optimize an in vivo OCT imaging model of the rodent spinal cord. In this study ...
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    10. Quantification of glucose levels in flowing blood using M-mode swept source optical coherence tomography

      Quantification of glucose levels in flowing blood using M-mode swept source optical coherence tomography
      Abstract  The increase of glucose levels in blood changes the viscosity of flowing fluids and shape of the erythrocytes. Both of these can affect the details of light scattering as can be quantified via decorrelation times measured by optical coherence tomography (OCT). The relative contributions of these competing effects have been studied by examining the motion dynamics of deformable asymmetrical (red blood cells, RBCs with ∼7 μm diameter and ∼2 ...
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    11. Noninvasive in vivo structural and vascular imaging of human oral tissues with spectral domain optical coherence tomography

      Noninvasive in vivo structural and vascular imaging of human oral tissues with spectral domain optical coherence tomography
      A spectral domain optical coherence tomography (SD-OCT) system and an oral imaging probe have been developed to visualize the microstructural morphology and microvasculature in the human oral cavity. Structural OCT images of ex vivo pig oral tissues with the histology of the same sites were acquired and compared for correlations. Structural in vivo OCT images of healthy human tissue as well as a pathologic site (ulcer) were obtained and analyzed ...
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    12. Vascular Wall Imaging of Vulnerable Atherosclerotic Carotid Plaques: Current State of the Art and Potential Future of Endovascular Optical Coherence Tomography

      Vascular Wall Imaging of Vulnerable Atherosclerotic Carotid Plaques: Current State of the Art and Potential Future of Endovascular Optical Coherence Tomography
      ...rtment of Electrical and Computer Engineering, and Medical Physics Program (V.X.D.Y.), Department of Physics, Ryerson University, Toronto, Ontario, Canada; Division of Neurosurgery (J.S., V.X.D.Y.), University of Toronto...
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    13. Feasibility and methodology of optical coherence tomography imaging of human intracranial aneurysms: ex vivo pilot study

      Feasibility and methodology of optical coherence tomography imaging of human intracranial aneurysms: ex vivo pilot study
      Rupture of intracranial aneurysm is a common cause of subarachnoid hemorrhage. An aneurysm may undergo microscopic morphological changes or remodeling of the vessel wall prior to rupture, which could potentially be imaged. In this study we present methods of tissue sample preparation of intracranial aneurysms and correlation between optical coherence tomography imaging and routine histology. OCT has a potential future in the assessment of microscopic features of aneurysms, which may ...
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    14. Biomechanical properties of soft tissue measurement using optical coherence elastography

      Biomechanical properties of soft tissue measurement using optical coherence elastography
      Optical Coherence Tomography (OCT) provides images at near histological resolution, which allows for the identification of micron sized morphological tissue structures. Optical coherence elastography (OCE) measures tissue displacement and utilizes the high resolution of OCT to generate high-resolution stiffness maps. In this work, we explored the potential of measuring shear wave propagation using OCE. A swept-source OCT system was used in this study. The laser had a center wavelength of ...
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    15. 46-60 of 92 « 1 2 3 4 5 6 »
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  2. About Ryerson University

    Ryerson University

    Ryerson University is Canada’s leader in innovative, career-focused education and a university clearly on the move. It is a distinctly urban university with a mission to serve societal need, and a long-standing commitment to engaging its community. Guided by a bold new Academic Plan, an ambitious research agenda, and a recently-completed Master Plan to revitalize the campus and surrounding neighbourhood, Ryerson is now the most applied-to university in Ontario relative to available spaces, and its reputation with business and community leaders continues to rise. In just a few years since the introduction of its first master's program, Ryerson has grown to host 2,000 graduate students in 34 programs, including nine at the doctoral level. The University now ranks third in Canada - and first in Ontario - in terms of research growth. And Ryerson is reshaping the downtown core of Toronto with two new buildings: a Photography Gallery and Research Centre in the heart of campus, and a Student Learning Centre on the site of the iconic Sam the Record Man property on Yonge Street, in the heart of the city. Since 1948, Ryerson has built its reputation on the strength of its academic curriculum, and offers close to 100 PhD, master's, and undergraduate programs, with a total enrolment of 25,000 and more than 65,000 registrations annually in The G. Raymond Chang School of Continuing Education.