1. Ryerson University

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    1. Mentioned In 92 Articles

    2. High speed, wide velocity dynamic range Doppler optical coherence tomography (Part IV): split spectrum processing in rotary catheter probes

      High speed, wide velocity dynamic range Doppler optical coherence tomography (Part IV): split spectrum processing in rotary catheter probes
      ...D. Yang^1,^3,^4,^* ^1Biophotonics and Bioengineering Laboratory, Dept. Electrical and Computer Engineering, Ryerson University, Toronto, ON, Canada ^2Department of Integrative Oncology - Cancer Imaging Unit, British ...
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    3. Detecting apoptosis in vivo and ex vivo using spectroscopic OCT and dynamic light scattering

      Detecting apoptosis in vivo and ex vivo using spectroscopic OCT and dynamic light scattering
      We present an in vivo implementation of a multi-parametric technique for detecting apoptosis using optical coherence tomography in a mouse tumor model. Solid tumors were grown from acute myeloid leukemia cells in the hind leg of SCID mice and treated with a single dose of cisplatin and dexamethasone to induce apoptosis. Both spectral features and speckle decorrelation times indicated good consistency between control mice and reasonable agreement with in vitro ...
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    4. Optical coherence tomography detection of shear wave propagation in MCF7 cell modules

      Optical coherence tomography detection of shear wave propagation in MCF7 cell modules
      In this work, we explored the potential of measuring shear wave propagation using Optical Coherence Elastography (OCE) in MCF7 cell modules (comprised of MCF7 cells and collagen) and based on a swept-source optical coherence tomography (OCT) system. Shear waves were generated using a piezoelectric transducer transmitting sine-wave bursts of 400 s, synchronized with an OCT swept source wavelength sweep imaging system. Acoustic radiation force was applied to the MCF7 cell ...
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    5. Imaging of electro-kinetic properties of tissue using the amplitude and the phase of optical coherence tomography

      Imaging of electro-kinetic properties of tissue using the amplitude and the phase of optical coherence tomography
      The electric field induced optical changes (EIOC) measured by the optical coherence tomography (OCT) reflect the local electro-kinetic properties of the tissue. In this study we developed a method to use the phase of the complex OCT images to map EIOC in tissue samples. Switching the polarity of the electric field induced significant reversible changes in the phase of the complex OCT images. Since the resulting phase was degraded by ...
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    6. Quantifying temperature changes in tissue-mimicking fluid phantoms using optical coherence tomography and envelope statistics

      Quantifying temperature changes in tissue-mimicking fluid phantoms using optical coherence tomography and envelope statistics
      Several therapies make use of a hypo or hyperthermia tissue environment to induce cell death in both benign and malignant tumors. Current progression in optical technologies, such as optical coherence tomography (OCT) and fiber Bragg gratings (FBG) sensors, could potentially provide viable information to explore the response of tissue when these temperature induced treatments are implemented. Studies were conducted with tissue-mimicking phantoms fabricated with polystyrene microspheres and glycerin to observe ...
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    7. Optical coherence tomography detection of shear wave propagation in inhomogeneous tissue equivalent phantoms and ex-vivo carotid artery samples

      Optical coherence tomography detection of shear wave propagation in inhomogeneous tissue equivalent phantoms and ex-vivo carotid artery samples
      In this work, we explored the potential of measuring shear wave propagation using optical coherence elastography (OCE) in an inhomogeneous phantom and carotid artery samples based on a swept-source optical coherence tomography (OCT) system. Shear waves were generated using a piezoelectric transducer transmitting sine-wave bursts of 400 s duration, applying acoustic radiation force (ARF) to inhomogeneous phantoms and carotid artery samples, synchronized with a swept-source OCT (SS-OCT) imaging system. The ...
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    8. Imaging the Electro-Kinetic Response of Biological Tissues with Optical Coherence Tomography (Thesis)

      Imaging the Electro-Kinetic Response of Biological Tissues with Optical Coherence Tomography (Thesis)
      This thesis reports on developing a novel approach to imaging the electro-kinetic response of biological tissues with optical coherence tomography (OCT). The changes of backscattered OCT signal from tissues were investigated with a low frequency AC electric field being applied to the tissues. Advanced processing algorithms were developed to analyze the amplitude and phase changes of OCT signal. Two-dimensional electrically induced optical changes (EIOC) amplitude and phase images related to ...
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    9. Digital image correlation–based optical coherence elastography

      Digital image correlation–based optical coherence elastography
      Optical coherence elastography (OCE) provides deformation or material properties, mapping of soft tissue. We aim to develop a robust speckle tracking OCE technique with improved resolution and accuracy. A digital image correlation (DIC)-based OCE technique was developed by combining an advanced DIC algorithm with optical coherence tomography (OCT). System calibration and measurement error evaluation demonstrated that this DIC-based OCE technique had a resolution of 0.6 m displacement and ...
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    10. Imaging pancreatobiliary ductal system with optical coherence tomography: A review

      Imaging pancreatobiliary ductal system with optical coherence tomography: A review
      An accurate, noninvasive and cost-effective method of in situ tissue evaluation during endoscopy would be highly advantageous for the detection of dysplasia or early cancer and for identifying different disease stages. Optical coherence tomography (OCT) is a noninvasive, high-resolution (1-10 m) emerging optical imaging method with potential for identifying microscopic subsurface features in the pancreatic and biliary ductal system. Tissue microstructure of pancreaticobiliary ductal system has been successfully imaged by ...
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    11. Analyzing effects of temperature on tissue equivalent phantoms using fiber Bragg gratings and optical coherence tomography

      Analyzing effects of temperature on tissue equivalent phantoms using fiber Bragg gratings and optical coherence tomography
      There exist a multitude of therapeutic options for the treatment of both benign and malignant tumors, where several of these options induce temperature changes in the tissue from several degrees centigrade to temperatures that ablate the region of interest (ROI). Recent advances in optical imaging technologies, namely optical coherence tomography (OCT) and Fiber Bragg Gratings (FBG), may provide the necessary hardware/software components to both monitor and quantify the direct ...
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    12. In vivo lung microvasculature visualized in three dimensions using fiber-optic color Doppler optical coherence tomography

      In vivo lung microvasculature visualized in three dimensions using fiber-optic color Doppler optical coherence tomography
      For the first time, the use of fiber-optic color Doppler optical coherence tomography (CDOCT) to map in vivo the three-dimensional (3-D) vascular network of airway segments in human lungs is demonstrated. Visualizing the 3-D vascular network in the lungs may provide new opportunities for detecting and monitoring lung diseases such as asthma, chronic obstructive pulmonary disease, and lung cancer. Our CDOCT instrument employs a rotary fiber-optic probe that provides simultaneous ...
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    13. Review of speckle and phase variance optical coherence tomography to visualize microvascular networks

      Review of speckle and phase variance optical coherence tomography to visualize microvascular networks
      High-resolution mapping of microvasculature has been applied to diverse body systems, including the retinal and choroidal vasculature, cardiac vasculature, the central nervous system, and various tumor models. Many imaging techniques have been developed to address specific research questions, and each has its own merits and drawbacks. Understanding, optimization, and proper implementation of these imaging techniques can significantly improve the data obtained along the spectrum of unique research projects to obtain ...
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    14. Optical coherence tomography detection of shear wave propagation in layered tissue equivalent phantoms

      Optical coherence tomography detection of shear wave propagation in layered tissue equivalent phantoms
      In this work, we explored the potential of measuring shear wave propagation using Optical Coherence Elastography (OCE) in a layered phantom and based on a swept-source optical coherence tomography (OCT) system. Shear waves were generated using a piezoelectric transducer transmitting sine-wave bursts of 400 s, synchronized with an OCT swept source wavelength sweep imaging system. The acoustic radiation force was applied to layered phantoms. The phantoms were composed of gelatin ...
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    15. 31-45 of 92 « 1 2 3 4 5 6 »
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  2. About Ryerson University

    Ryerson University

    Ryerson University is Canada’s leader in innovative, career-focused education and a university clearly on the move. It is a distinctly urban university with a mission to serve societal need, and a long-standing commitment to engaging its community. Guided by a bold new Academic Plan, an ambitious research agenda, and a recently-completed Master Plan to revitalize the campus and surrounding neighbourhood, Ryerson is now the most applied-to university in Ontario relative to available spaces, and its reputation with business and community leaders continues to rise. In just a few years since the introduction of its first master's program, Ryerson has grown to host 2,000 graduate students in 34 programs, including nine at the doctoral level. The University now ranks third in Canada - and first in Ontario - in terms of research growth. And Ryerson is reshaping the downtown core of Toronto with two new buildings: a Photography Gallery and Research Centre in the heart of campus, and a Student Learning Centre on the site of the iconic Sam the Record Man property on Yonge Street, in the heart of the city. Since 1948, Ryerson has built its reputation on the strength of its academic curriculum, and offers close to 100 PhD, master's, and undergraduate programs, with a total enrolment of 25,000 and more than 65,000 registrations annually in The G. Raymond Chang School of Continuing Education.