1. Ruikang K. Wang

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    1. Mentioned In 138 Articles

    2. Laser induced surface acoustic wave combined with phase sensitive optical coherence tomography for superficial tissue characterization: a solution for practical application

      Laser induced surface acoustic wave combined with phase sensitive optical coherence tomography for superficial tissue characterization: a solution for practical application
      ..., and Zhihong Huang »View Author Affiliations Chunhui Li,^1 Guangying Guan,^2,^3 Fan Zhang,^2 Ghulam Nabi,^1 Ruikang K. Wang,^2,^3 and Zhihong Huang^2 ^1Division of Imaging Technology, School of Medicine, University o...
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    3. Improved microcirculation imaging of human skin in vivo using optical microangiography with a correlation mapping mask

      Improved microcirculation imaging of human skin in vivo using optical microangiography with a correlation mapping mask

      Optical microangiography based on optical coherence tomography (OCT) is prone to noise that arises from a static tissue region. Here, we propose a method that can significantly reduce this noise. The method is developed based on an approach that uses the magnitude information of OCT signals to produce tissue microangiograms, especially suitable for the case where a swept-source OCT system is deployed. By combined use of two existing OCT microangiography methods—ultrahigh-sensitive optical microangiography (UHS-OMAG) and correlation mapping OCT (cmOCT)—the final tissue microangiogram is generated by masking UHS-OMAG image using the binary representation of cmOCT image. We find that ...

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    4. University of Washington Receives NIH Grant for Studying Non-Invasive Real-Time Label-Free 3D Imaging of Retinal Microcircuation

      University of Washington Receives NIH Grant for Studying Non-Invasive Real-Time Label-Free 3D Imaging of Retinal Microcircuation
      ...udying Non-Invasive Real-Time Label-Free 3D Imaging of Retinal Microcircuation. The principal investigator is Ruikang Wang. The program began in 2014 and ends in 2018. Below is a summary of the proposed work. Non-invasi...
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    5. Noninvasive Imaging of Retinal Morphology and Microvasculature in Obese Mice using Optical Coherence Tomography and Optical Microangiography

      Noninvasive Imaging of Retinal Morphology and Microvasculature in Obese Mice using Optical Coherence Tomography and Optical Microangiography

      Purpose:To evaluate early diabetes-induced changes in retinal thickness and microvasculature in a type II diabetic mouse model using OCT/OMAG. Methods:22 week old obese BTBR mice (OB, n=10) and wild type control mice (WT, n=10) were imaged. Three-dimensional data were captured with OCT using an ultrahigh sensitive OMAG scanning protocol for 3D angiography of the retina and dense A-scan protocol for measurement of the total retinal blood flow (RBF) rate. The thickness of the nerve fiber layer (NFL) and NFL to inner plexiform layer (IPL) were measured and compared between OB and WT mice. The linear ...

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    6. Shear wave pulse compression for dynamic elastography using phase-sensitive optical coherence tomography

      Shear wave pulse compression for dynamic elastography using phase-sensitive optical coherence tomography

      Assessing the biomechanical properties of soft tissue provides clinically valuable information to supplement conventional structural imaging. In the previous studies, we introduced a dynamic elastography technique based on phase-sensitive optical coherence tomography (PhS-OCT) to characterize submillimetric structures such as skin layers or ocular tissues. Here, we propose to implement a pulse compression technique for shear wave elastography. We performed shear wave pulse compression in tissue-mimicking phantoms. Using a mechanical actuator to generate broadband frequency-modulated vibrations (1 to 5 kHz), induced displacements were detected at an equivalent frame rate of 47 kHz using a PhS-OCT. The recorded signal was digitally compressed ...

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    7. Changes in cochlear blood flow in mice due to loud sound exposure measured with Doppler optical microangiography and laser Doppler flowmetry

      Changes in cochlear blood flow in mice due to loud sound exposure measured with Doppler optical microangiography and laser Doppler flowmetry
      ...ography and laser Doppler flowmetry Authors: Roberto Reif, Zhongwei Zhi, Suzan Dziennis, Alfred L. Nuttall, Ruikang K. Wang Abstract In this work we determined the contributions of loud sound exposure (LSE) on coc...
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  2. About Ruikang K. Wang

    Ruikang K. Wang

    Ruikang K. Wang is a professor in the biomedical engineering department at Washington University. He interests include: High resolution functional optical imaging using coherence gating and confocal gating techniques as applied to healthcare, Optical biopsy and functional imaging in tissue engineering, Photoacoustic imaging, and Light propagation in biological tissue.