1. Ruikang K. Wang

    0 Comments Leave a Comment

    1-15 of 326 1 2 3 4 ... 20 21 22 »
    1. Mentioned In 326 Articles

    2. Polarization sensitive optical coherence tomography for imaging microvascular information within living tissue without polarization-induced artifacts

      Polarization sensitive optical coherence tomography for imaging microvascular information within living tissue without polarization-induced artifacts
      When imaging birefringent samples using optical coherence tomography angiography (OCTA), the phase retardation may appear opposite to the phase change due to the blood flow in the orthogonal signals, for which a cancellation effect can occur when deriving OCTA signals. This effect can diminish the ability of OCTA to detect vascular information, leading to an erroneous interpretation of the final OCTA images. To mitigate this issue, we demonstrate polarization-sensitive optical ...
      Read Full Article
    3. Handheld swept-source optical coherence tomography guided by smartphone-enabled wide-field autofluorescence photography for imaging facial sebaceous glands

      Handheld swept-source optical coherence tomography guided by smartphone-enabled wide-field autofluorescence photography for imaging facial sebaceous glands
      We report a method to image facial sebaceous glands (SGs) using smartphone-enabled wide-field autofluorescence photography (AFP) and handheld swept-source optical coherence tomography (SS-OCT). Smartphone-enabled AFP provides a 2D wide-field fluorescence image that is used both as a functional mapping of the sebum and a positioning guidance for OCT imaging of the SG. Following the guidance, handheld SS-OCT conducts the volume scan to investigate depth-resolved conditions of the SG in the ...
      Read Full Article
    4. Macular microvascular parameters in the ganglion cell-inner plexiform layer derived by optical coherence tomography angiography: Vascular structure-central visual function analysis

      Macular microvascular parameters in the ganglion cell-inner plexiform layer derived by optical coherence tomography angiography: Vascular structure-central visual function analysis
      Purpose To investigate the relationships between global and sectoral macular vascular microcirculation parameters in the ganglion cell-inner plexiform layer (GCIPL) assessed by optical coherence tomography angiography (OCTA), and global and sectoral visual field (VF) central mean sensitivity (CMS) assessed by standard automated perimetry. Methods Fifty-four eyes with open angle glaucoma were scanned using a swept-source OCTA (Plex Elite 9000, Zeiss, Dublin, CA) and macular vascular microcirculation was measured by calculating ...
      Read Full Article
    5. Optical microangiography reveals temporal and depth-resolved hemodynamic change in mouse barrel cortex during whisker stimulation

      Optical microangiography reveals temporal and depth-resolved hemodynamic change in mouse barrel cortex during whisker stimulation
      Significance: Cerebral blood flow (CBF) regulation at neurovascular coupling (NVC) plays an important role in normal brain functioning to support oxygen delivery to activating neurons. Therefore, studying the mechanisms of CBF adjustment is crucial for the improved understanding of brain activity. Aim: We investigated the temporal profile of hemodynamic signal change in mouse cortex caused by neural activation and its variation over cortical depth. Approach: Following the cranial window surgery ...
      Read Full Article
    6. Semi-automated registration and segmentation for gingival tissue volume measurement on 3D OCT images

      Semi-automated registration and segmentation for gingival tissue volume measurement on 3D OCT images
      The change in gingival tissue volume may be used to indicate changes in gingival inflammation, which may be useful for the clinical assessment of gingival health. Properly quantifying gingival tissue volume requires a robust technique for accurate registration and segmentation of longitudinally captured 3-dimensional (3D) images. In this paper, a semi-automated registration and segmentation method for micrometer resolution measurement of gingival-tissue volume is proposed for 3D optical coherence tomography (OCT ...
      Read Full Article
    7. Guidelines for imaging the choriocapillaris using OCT angiography

      Guidelines for imaging the choriocapillaris using OCT angiography
      Purpose To provide guidance on how to appropriately quantitate various choriocapillaris (CC) parameters with optical coherence tomography angiography (OCTA). Design Evidence-based perspective. Methods Review of literature and experience of authors. Results Accurate and reliable quantification of the CC using OCTA requires that the CC can be visualized and that the measurements of various CC parameters are validated. For accurate visualization, the selected CC slab must be physiologically sound, must produce ...
      Read Full Article
    8. Post Doc Positions in Optical Coherence Tomography and Optical Imaging at University of Washington

      Post Doc Positions in Optical Coherence Tomography and Optical Imaging at University of Washington
      There are a number of postdoctoral/professional scientist positions immediately available in Wang Lab [Biophotonics and Imaging Laboratory (BAIL)], Department of Bioengineering and Department of Ophthalmology, University of Washington. We are located in beautiful and best to live Seattle area. We are looking for highly motivated individuals to join our vibrant lab to develop innovative optical imaging techniques (e.g. optical coherence tomography and angiography, and smartphone-based healthcare technology) for ...
      Read Full Article
    9. Automated vessel diameter quantification and vessel tracing for OCT angiography

      Automated vessel diameter quantification and vessel tracing for OCT angiography
      Optical coherence tomography angiography (OCTA) is capable of non‐invasively imaging the vascular networks within circulatory tissue beds in vivo. Following improvements in OCTA image quality, it is now possible to extract vascular parameters from imaging data to potentially facilitate the diagnosis and treatment of human disease. In this paper, we present a method for automated mapping of vessel diameter down to the individual capillary level, through gradient‐guided minimum ...
      Read Full Article
    10. OCT Angiography to Predict Geographic Atrophy Progression using Choriocapillaris Flow Void as a Biomarker

      OCT Angiography to Predict Geographic Atrophy Progression using Choriocapillaris Flow Void as a Biomarker
      Purpose : To investigate the relationship between choriocapillaris (CC) flow void (FV) percentage and geographic atrophy (GA) growth rate, and study how variations in FV percentage surrounding GA predict regional GA growth. Methods : This prospective, longitudinal study enrolled subjects with GA secondary to nonexudative age-related macular degeneration. Optical coherence tomography angiography imaged the CC and FV percentage was evaluated using a validated algorithm. GA growth rate was measured as the difference ...
      Read Full Article
    11. Quantifying Subclinical and Longitudinal Microvascular Changes Following Episcleral Plaque Brachytherapy Using Spectral Domain–Optical Coherence Tomography Angiography

      Quantifying Subclinical and Longitudinal Microvascular Changes Following Episcleral Plaque Brachytherapy Using Spectral Domain–Optical Coherence Tomography Angiography
      Purpose: This work assesses longitudinal microvascular changes in eyes treated with iodine-125 episcleral plaque brachytherapy (EPB). Methods: High-resolution optical coherence tomography angiograms (OCTAs) of the central 33-mm macula were obtained from iodine-125 EPBtreated and untreated fellow eyes of 61 patients. Previously validated semiautomated algorithms quantified capillary density (vessel skeleton density [VSD]) and caliber (vessel diameter index). Nonperfusion was also quantified as flow impairment region (FIR). Examinations from treated and fellow ...
      Read Full Article
    12. Peripapillary and Macular Microcirculation in Glaucoma Patients of African and European Descent Using Optical Coherence Tomography Angiography

      Peripapillary and Macular Microcirculation in Glaucoma Patients of African and European Descent Using Optical Coherence Tomography Angiography
      Prcis: We found no significant differences in peripapillary and macula microcirculation blood flow metrics in eyes with open angle glaucoma of African descent (AD) and European Descent (ED) as detected by optical coherence tomography-angiography ( OCTA ). Purpose: To investigate the peripapillary retinal nerve fiber layer (RNFL) and macular vascular microcirculation in subjects of African descent (AD) and European descent (ED) with open-angle glaucoma using optical coherence tomography-angiography ( OCTA ). Patients and Methods ...
      Read Full Article
    13. Validation of a Compensation Strategy used to Detect Choriocapillaris Flow Deficits Under Drusen with Swept Source OCT Angiography

      Validation of a Compensation Strategy used to Detect Choriocapillaris Flow Deficits Under Drusen with Swept Source OCT Angiography
      Purpose A compensation strategy that was developed to measure the choriocapillaris (CC) flow deficits (FDs) under drusen was tested in eyes with large drusen from age-related macular degeneration (AMD) before and after the drusen spontaneously resolved without evidence of disease progression. Design Prospective, observational consecutive case series. Methods Patients with AMD were enrolled in a prospective SS-OCT imaging study (PLEX Elite 9000, Carl Zeiss Meditec). Consecutive eyes with large drusen ...
      Read Full Article
    14. University of Washington Receives NIH Grant for Ultra-Wide Field Optical Coherence Tomography Based Angiography for Imaging Diabetic Retinopathy

      University of Washington Receives NIH Grant for Ultra-Wide Field Optical Coherence Tomography Based Angiography for Imaging Diabetic Retinopathy
      ...ptical Coherence Tomography Based Angiography for Imaging Diabetic Retinopathy. The principal investigator is Ruikang Wang. Below is a summary of the proposed work. 

      The increasin...

      Read Full Article
    15. Clinical Utility of Triplicate En Face Image Averaging for Optical Coherence Tomography Angiography in Glaucoma and Glaucoma Suspects

      Clinical Utility of Triplicate En Face Image Averaging for Optical Coherence Tomography Angiography in Glaucoma and Glaucoma Suspects
      Prcis: Averaging triplicate en face angiograms of the radial peripapillary capillary plexus with optical coherence tomography angiography (OCTA) improves vessel visualization, reduces vessel density parameters, and increases the diagnostic accuracy for glaucoma of one such parameter. Purpose: To test the hypothesis that triplicate averaging of the radial peripapillary capillary (RPC) layer improves visualization and diagnostic accuracy of optical coherence tomography angiography (OCTA) for glaucoma . Methods: This is a cross-sectional study ...
      Read Full Article
    16. Mean-Subtraction Method for De-shadowing of Tail Artifacts in Cerebral OCTA Images: A Proof of Concept

      Mean-Subtraction Method for De-shadowing of Tail Artifacts in Cerebral OCTA Images: A Proof of Concept
      When imaging brain vasculature with optical coherence tomography angiography (OCTA), volumetric analysis of cortical vascular networks in OCTA datasets is frequently challenging due to the presence of artifacts, which appear as multiple-scattering tails beneath superficial large vessels in OCTA images. These tails shadow underlying small vessels, making the assessment of vascular morphology in the deep cortex difficult. In this work, we introduce an image processing technique based on mean subtraction ...
      Read Full Article
    17. 1-15 of 326 1 2 3 4 ... 20 21 22 »
  1. Categories

    1. Applications:

      Art, Cardiology, Dentistry, Dermatology, Developmental Biology, Gastroenterology, Gynecology, Microscopy, NDE/NDT, Neurology, Oncology, Ophthalmology, Other Non-Medical, Otolaryngology, Pulmonology, Urology
    2. Business News:

      Acquisition, Clinical Trials, Funding, Other Business News, Partnership, Patents
    3. Technology:

      Broadband Sources, Probes, Tunable Sources
    4. Miscellaneous:

      Jobs & Studentships, Student Theses, Textbooks
  2. About Ruikang K. Wang

    Ruikang K. Wang

    Ruikang K. Wang is a professor in the biomedical engineering department at Washington University. He interests include: High resolution functional optical imaging using coherence gating and confocal gating techniques as applied to healthcare, Optical biopsy and functional imaging in tissue engineering, Photoacoustic imaging, and Light propagation in biological tissue.