1. Ruikang K. Wang

    0 Comments Leave a Comment

    1-15 of 246 1 2 3 4 ... 15 16 17 »
    1. Mentioned In 246 Articles

    2. Imaging collector channel entrance with a new intraocular micro-probe swept-source optical coherence tomography

      Imaging collector channel entrance with a new intraocular micro-probe swept-source optical coherence tomography
      Purpose To describe the use of a newly developed side-viewing catheter probe to provide the cross-sectional images of collector channel entrance (CCE), achieved by swept-source optical coherence tomography (SS-OCT). Methods A side-viewing SS-OCT catheter probe was developed that has a core probe diameter of 0.15 mm and an outer diameter of 0.25 mm, for the purpose of imaging CCEs within eye globe. Cadaver eyes harvested from swine and ...
      Read Full Article
    3. Quantitative microvascular analysis of retinal venous occlusions by spectral domain optical coherence tomography angiography

      Quantitative microvascular analysis of retinal venous occlusions by spectral domain optical coherence tomography angiography
      Purpose To quantitatively evaluate the retinal microvasculature in human subjects with retinal venous occlusions (RVO) using optical coherence tomography angiography (OCTA). Design Retrospective, cross-sectional, observational case series. Participants Sixty subjects (84 eyes) were included (20 BRVO, 14 CRVO, 24 unaffected fellow eyes, and 26 controls). Methods OCTA was performed on a prototype, spectral domain-OCTA system in the 3x3mm central macular region. Custom software was used to quantify morphology and density ...
      Read Full Article
    4. OHSU Receives NIH Grant for Studies in Glaucomatous Optic Nerve Damage

      OHSU Receives NIH Grant  for Studies in Glaucomatous Optic Nerve Damage
      ...assessment of retina and ONH perfusion with Doppler-Optical Coherence Tomography, adapted for rat eyes by Dr. Ruikang Wang at the University of Washington. Specific Aim 3 will demonstrate that inhibition of the Jak2/Stat...
      Read Full Article
    5. Comparison Between Spectral-Domain and Swept-Source Optical Coherence Tomography Angiographic Imaging of Choroidal Neovascularization

      Comparison Between Spectral-Domain and Swept-Source Optical Coherence Tomography Angiographic Imaging of Choroidal Neovascularization
      Purpose : The purpose of this study was to compare imaging of choroidal neovascularization (CNV) using swept-source (SS) and spectral-domain (SD) optical coherence tomography angiography (OCTA). Methods : Optical coherence tomography angiography was performed using a 100-kHz SS-OCT instrument and a 68-kHz SD-OCTA instrument (Carl Zeiss Meditec, Inc.). Both 3 3- and 6 6-mm 2 scans were obtained on both instruments. The 3 3-mm 2 SS-OCTA scans consisted of 300 A-scans per ...
      Read Full Article
    6. Ultralong-range optical coherence tomography-based angiography by akinetic swept source

      Ultralong-range optical coherence tomography-based angiography by akinetic swept source
      Most of current OCT-based angiography suffers from small FOV with short imaging range. Here we implement an ultralong-range OCT system for vascular imaging based on an akinetic swept source. This swept-source OCT (SS-OCT) system enables us to achieve up to 46 mm long imaging range with unprecedented roll-off performance. To compare with traditional spectral domain OCT (SD-OCT) system, we demonstrated the vascular imaging of the entire mice brain with wide ...
      Read Full Article
    7. Non-contact rapid optical coherence elastography by high-speed 4D imaging of elastic waves

      Non-contact rapid optical coherence elastography by high-speed 4D imaging of elastic waves
      Shear wave OCE (SW-OCE) uses an OCT system to track propagating mechanical waves, providing the information needed to map the elasticity of the target sample. In this study we demonstrate high speed, 4D imaging to capture transient mechanical wave propagation. Using a high-speed Fourier domain mode-locked (FDML) swept-source OCT (SS-OCT) system operating at ~1.62 MHz A-line rate, the equivalent volume rate of mechanical wave imaging is 16 kvps (kilo-volumes ...
      Read Full Article
    8. Optical coherence tomography based angiography [Invited]

      Optical coherence tomography based angiography [Invited]
      Optical coherence tomography (OCT)-based angiography (OCTA) providesin vivo, three-dimensional vascular information by the use of flowing red blood cells as intrinsic contrast agents, enabling the visualization of functional vessel networks within microcirculatory tissue beds non-invasively, without a need of dye injection. Because of these attributes, OCTA has been rapidly translated to clinical ophthalmology within a short period of time in the development. Various OCTA algorithms have been developed to ...
      Read Full Article
    9. Acoustic micro-tapping for non-contact 4D imaging of tissue elasticity

      Acoustic micro-tapping for non-contact 4D imaging of tissue elasticity
      Elastography plays a key role in characterizing soft media such as biological tissue. Although this technology has found widespread use in both clinical diagnostics and basic science research, nearly all methods require direct physical contact with the object of interest and can even be invasive. For a number of applications, such as diagnostic measurements on the anterior segment of the eye, physical contact is not desired and may even be ...
      Read Full Article
    10. Wide field and highly sensitive angiography based on optical coherence tomography with akinetic swept source

      Wide field and highly sensitive angiography based on optical coherence tomography with akinetic swept source
      Wide-field vascular visualization in bulk tissue that is of uneven surface is challenging due to the relatively short ranging distance and significant sensitivity fall-off for most current optical coherence tomography angiography (OCTA) systems. We report a long ranging and ultra-wide-field OCTA (UW-OCTA) system based on an akinetic swept laser. The narrow instantaneous linewidth of the swept source with its high phase stability, combined with high-speed detection in the system enable ...
      Read Full Article
    11. Association between OCT-based microangiography perfusion indices and diabetic retinopathy severity

      Association between OCT-based microangiography perfusion indices and diabetic retinopathy severity
      Aim To evaluate the association between retinal capillary non-perfusion and diabetic retinopathy (DR) severity using optical coherence tomography-based microangiography (OMAG). Methods 33 patients (51 eyes) with a history of diabetes underwent imaging with a 68 kHz Cirrus-5000 spectral domain OMAG prototype. Demographic and clinical characteristics were collected. The perfusion index (PI) was defined as per cent coverage of area by retinal vessels with flow, measured within a minimum of 6 ...
      Read Full Article
    12. Projection Artifact Removal Improves Visualization and Quantitation of Macular Neovascularization Imaged by Optical Coherence Tomography Angiography

      Projection Artifact Removal Improves Visualization and Quantitation of Macular Neovascularization Imaged by Optical Coherence Tomography Angiography
      Purpose To visualize and quantify the size and vessel density of macular neovascularization (MNV) using optical coherence tomography angiography (OCTA) with a projection artifact removal algorithm. Design Multicenter, observational study. Participants Subjects with MNV in 1 eye. Methods Patients were imaged using either a swept-source OCTA prototype system or a spectral-domain OCTA prototype system. The optical microangiography (OMAG) algorithm was used to generate the OCTA images. Projection artifacts from the ...
      Read Full Article
    13. Cerebral capillary velocimetry based on temporal OCT speckle contrast

      Cerebral capillary velocimetry based on temporal OCT speckle contrast
      We propose a new optical coherence tomography (OCT) based method to measure red blood cell (RBC) velocities of single capillaries in the cortex of rodent brain. This OCT capillary velocimetry exploits quantitative laser speckle contrast analysis to estimate speckle decorrelation rate from the measured temporal OCT speckle signals, which is related to microcirculatory flow velocity. We hypothesize that OCT signal due to sub-surface capillary flow can be treated as the ...
      Read Full Article
    14. Evaluation of bilateral central retinal artery occlusions with optical coherence tomography-based microangiography

      Evaluation of bilateral central retinal artery occlusions with optical coherence tomography-based microangiography
      Background We report a case of bilateral central retinal artery occlusion and the evaluation of retinal vasculature and capillaries by using optical coherence tomography angiography. Case presentation A 75-year-old white man presented with central retinal artery occlusion in one eye and underwent a carotid angioplasty. Upon discontinuing anticoagulant, he had a subsequent central retinal artery occlusion in the other eye. Optical coherence tomography angiography images were obtained to compare the ...
      Read Full Article
    15. Long-range and wide field of view optical coherence tomography for in vivo 3D imaging of large volume object based on akinetic programmable swept source

      Long-range and wide field of view optical coherence tomography for in vivo 3D imaging of large volume object based on akinetic programmable swept source
      ... 036005 (2016). [Crossref] [PubMed] S. Song, W. Wei, B.-Y. Hsieh, I. Pelivanov, T. T. Shen, M. O’Donnell, and R. K. Wang, “Strategies to improve phase-stability of ultrafast swept source optical coherence tomography for ...
      Read Full Article
    16. Optical coherence tomography based microangiography provides an ability to longitudinally image arteriogenesis in vivo

      Optical coherence tomography based microangiography provides an ability to longitudinally image arteriogenesis in vivo
      Purpose : To perform an analysis of optical coherence tomography (OCT) abnormalities in patients with MEWDS, during the acute and recovery stages, using enhanced depth imaging-OCT (EDI-OCT). Methods : A retrospective case series of five patients with MEWDS was included. EDI-OCT imaging was evaluated to detect retinal and choroidal features. Results : In the acute phase, focal impairment of the ellipsoid zone and external limiting membrane, hyperreflective dots in the inner choroid, and ...
      Read Full Article
    17. 1-15 of 246 1 2 3 4 ... 15 16 17 »
  1. Categories

    1. Applications:

      Art, Cardiology, Dentistry, Dermatology, Developmental Biology, Gastroenterology, Gynecology, Microscopy, NDE/NDT, Neurology, Oncology, Ophthalmology, Other Non-Medical, Otolaryngology, Pulmonology, Urology
    2. Business News:

      Acquisition, Clinical Trials, Funding, Other Business News, Partnership, Patents
    3. Technology:

      Broadband Sources, Probes, Tunable Sources
    4. Miscellaneous:

      Jobs & Studentships, Student Theses, Textbooks
  2. About Ruikang K. Wang

    Ruikang K. Wang

    Ruikang K. Wang is a professor in the biomedical engineering department at Washington University. He interests include: High resolution functional optical imaging using coherence gating and confocal gating techniques as applied to healthcare, Optical biopsy and functional imaging in tissue engineering, Photoacoustic imaging, and Light propagation in biological tissue.