1. Ruchire Eranga Wijesinghe

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    1. Mentioned In 36 Articles

    2. Non-invasive optical screening of Streptococcus Pneumonia based inflammatory changes of the tympanic membrane and mastoid mucosa in guinea pig otitis media using optical coherence tomography

      Non-invasive optical screening of Streptococcus Pneumonia based inflammatory changes of the tympanic membrane and mastoid mucosa in guinea pig otitis media using optical coherence tomography
      Abstract: The accurate screening of otitis media (OM) lies in clarifying the numerous confounding and quantitative factors that are discovered during primary inspections. Increased awareness about bacterial biofilms and inflammation has allowed researchers to develop a better understanding of the bacterial infections that occur in the middle ear. In this study, four live guinea pigs were inoculated with Streptococcus pneumonia to induce OM-related inflammatory changes. Since optical techniques have been ...
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    3. Assessment of the Inner Surface Roughness of 3D Printed Dental Crowns via Optical Coherence Tomography Using a Roughness Quantification Algorithm

      Assessment of the Inner Surface Roughness of 3D Printed Dental Crowns via Optical Coherence Tomography Using a Roughness Quantification Algorithm
      Abstract: Dental crowns are used to restore decayed or chipped teeth, where their surfaces play a key role in this restoration process, as they affect the fitting and stable bonding of the prostheses. The surface texture of crowns can interfere with this restoration process, therefore the measurement of their inner surface roughness is very important but difficult to achieve using conventional imaging methods. In this study, the inner surfaces of ...
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    4. Dynamic compensation of path length difference in optical coherence tomography by an automatic temperature control system of optical fiber

      Dynamic compensation of path length difference in optical coherence tomography by an automatic temperature control system of optical fiber
      Optical fiber is widely used in optical coherence tomography (OCT) to propagate light precisely with low attenuation and low dispersion. However, the total optical path length within the optical fiber varies in accordance with changes of the temperature. This leads changes in the total optical travel path of the interfering signals and results in shifting of OCT image position to an unintended depth pixel value. In this paper, we presented ...
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    5. Diagnostic Accuracy of Quantitative Micro-Elastography for Margin Assessment in Breast-Conserving Surgery

      Diagnostic Accuracy of Quantitative Micro-Elastography for Margin Assessment in Breast-Conserving Surgery
      Inadequate margins in breast-conserving surgery (BCS) are associated with an increased likelihood of local recurrence of breast cancer. Currently, approximately 20% of BCS patients require repeat surgery due to inadequate margins at the initial operation. Implementation of an accurate, intraoperative margin assessment tool may reduce this re-excision rate. This study determined, for the first time, the diagnostic accuracy of quantitative micro-elastography (QME), an optical coherence tomography (OCT)based elastography technique ...
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    6. High-resolution Imaging Coupled With Elastography May Accurately Detect Breast Cancer in Surgical Margins

      High-resolution Imaging Coupled With Elastography May Accurately Detect Breast Cancer in Surgical Margins
      A high-resolution, three-dimensional imaging technique, when combined with quantitative measurement of tissue elasticity, could accurately detect cancer within the resected margins of surgical specimens taken from patients undergoing breast-conserving surgery, according to a study published in Cancer Research , a journal of the American Association for Cancer Research. Despite living in the digital age, surgeons must routinely rely on their eyesight and sense of touch to determine if they have removed ...
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    7. Optical Interferometric Fringe Pattern-Incorporated Spectrum Calibration Technique for Enhanced Sensitivity of Spectral Domain Optical Coherence Tomography

      Optical Interferometric Fringe Pattern-Incorporated Spectrum Calibration Technique for Enhanced Sensitivity of Spectral Domain Optical Coherence Tomography
      Depth-visualizing sensitivity can be degraded due to imperfect optical alignment and non-equidistant distribution of optical signals in the pixel array, which requires a measurement of the re-sampling process. To enhance this depth-visualizing sensitivity, reference and sample arm-channeled spectra corresponding to different depths using mirrors were obtained to calibrate the spectrum sampling prior to Fourier transformation. During the process, eight interferogram patterns corresponding to point spread function (PSF) signals at eight ...
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    8. Handheld volumetric manual compression‐based quantitative micro‐elastography

      Handheld volumetric manual compression‐based quantitative micro‐elastography
      Compression optical coherence elastography typically requires a mechanical actuator to impart a controlled uniform strain to the sample. However, for handheld scanning, this adds complexity to the design of the probe and the actuator stroke limits the amount of strain that can be applied. In this work, we present a new volumetric imaging approach that utilises bidirectional manual compression via the natural motion of the user's hand to induce ...
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    9. Identification of multi-dimensional thread geometry using depth-resolved swept-source optical coherence tomography for assessment of dental implant fabrication

      Identification of multi-dimensional thread geometry using depth-resolved swept-source optical coherence tomography for assessment of dental implant fabrication
      The geometrical characteristics of dental implants, such as thread depth and width, facing angle, pitch, and surface roughness, are important to assess their stability and osseointegration after implant surgery. Herein, we demonstrate the potential use of depth-resolved swept-source optical coherence tomography (SS-OCT) to assess the structural quality of widely used dental implants. The implemented SS-OCT system was centered at a wavelength of 1300 nm with a 100 nm full-width at ...
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    10. An averaged intensity difference detection algorithm for identification of human gingival sulcus in optical coherence tomography images

      An averaged intensity difference detection algorithm for identification of human gingival sulcus in optical coherence tomography images
      In the past decade, there has been an increase in the development of sensitive, highresolution, non-invasive diagnostic methods for periodontic diseases. Optical coherence tomography (OCT) has attracted considerable attention in clinical settings. In this study, a reliable, robust algorithm for the detection of gingival sulcus in 2D OCT cross-sectional images is proposed. Previously, the measurement of gingival sulcus in OCT images has been performed by manual identification using two-dimensional (2D ...
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    11. Non-Invasive Morphological Characterization of Rice Leaf Bulliform and Aerenchyma Cellular Regions Using Low Coherence Interferometry

      Non-Invasive Morphological Characterization of Rice Leaf Bulliform and Aerenchyma Cellular Regions Using Low Coherence Interferometry
      Non-invasive investigation of rice leaf specimens to characterize the morphological formation and particular structural information that is beneficial for agricultural perspective was demonstrated using a low coherence interferometric method called swept source optical coherence tomography (SS-OCT). The acquired results non-invasively revealed morphological properties of rice leaf, such as bulliform cells; aerenchyma, parenchyma, and collenchyma layer; and vascular bundle. Beside aforementioned morphologic characteristics, several leaf characteristics associated with cytological mechanisms of ...
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    12. Non-ionized, High-resolution Measurement of Internal and Marginal Discrepancies of Dental Prosthesis Using Optical Coherence Tomography

      Non-ionized, High-resolution Measurement of Internal and Marginal Discrepancies of Dental Prosthesis Using Optical Coherence Tomography
      An internal and marginal fit between prosthesis and abutment are important factors of the durability of dental prosthesis. In this study we have proposed the use of swept-source optical coherence tomography (SS-OCT) as a novel application for non-ionized and high-resolution measurements of internal and marginal discrepancies at anatomically critical four points, such as occlusal, angle, axial, and margin during prosthesis attachment. A tooth model was fabricated by 3D printing technique ...
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    13. Clinical Utility of Intraoperative Tympanomastoidectomy Assessment Using a Surgical Microscope Integrated with an Optical Coherence Tomography

      Clinical Utility of Intraoperative Tympanomastoidectomy Assessment Using a Surgical Microscope Integrated with an Optical Coherence Tomography
      Significant technical and optical advances are required for intraoperative optical coherence tomography (OCT) to be utilized during otological surgeries. Integrating OCT with surgical microscopy makes it possible to evaluate soft tissue in real-time and at a high resolution. Herein, we describe an augmented-reality, intraoperative OCT/microscope system with an extended working distance of 280mm, providing more space for surgical manipulation than conventional techniques. We initially performed ex vivo experiments to ...
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    14. Non-destructive identification of weld-boundary and porosity formation during laser transmission welding by using optical coherence tomography

      Non-destructive identification of weld-boundary and porosity formation during laser transmission welding by using optical coherence tomography
      Laser transmission welding offers significant benefits over conventional welding techniques enabling single-stage rapid plastic joining. The quality of laser transmission welded products are commonly assessed by measuring the weld penetration depth, hardened weld boundary, and inspecting the formation of porosity. However, existing methods of verification are inevitably accompanied by destruction of the specimen. Thus, non-destructive quality assessment methods for laser transmission welding have gained attention recently. Here, we demonstrated an ...
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    15. Biophotonic approach for the characterization of initial bitter-rot progression on apple specimens using optical coherence tomography assessments

      Biophotonic approach for the characterization of initial bitter-rot progression on apple specimens using optical coherence tomography assessments
      The tremendous advances achieved in the biophotonics technologies have intensified the necessity for non-invasive modalities that can characterize diverse biological materials with increased sensitivity and resolution. Optical coherence tomography (OCT) is one of the techniques that has been applied for biological applications in medicine and agriculture to identify structural properties. Herein, we report the successful incorporation of OCT for the identification of morphological changes that occur as a result of ...
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    16. Numerical-Sampling-Functionalized Real-Time Index Regulation for Direct k-Domain Calibration in Spectral Domain Optical Coherence Tomography

      Numerical-Sampling-Functionalized Real-Time Index Regulation for Direct k-Domain Calibration in Spectral Domain Optical Coherence Tomography
      An index-regulation technique functionalized by numerical sampling for direct calibration of the non-linear wavenumber ( k )-domain to a linear domain in spectral domain optical coherence tomography (SD-OCT) is proposed. The objective of the developed method is to facilitate high-resolution identification of microstructures in biomedical imaging. Subjective optical alignments caused by nonlinear sampling of interferograms in the k -domain tend to hinder depth-dependent signal-to-noise ratios (SNR) and axial resolution in SD-OCT ...
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    17. 1-15 of 36 1 2 3 »
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  2. About Ruchire Eranga Wijesinghe

    Ruchire Eranga Wijesinghe

    Ruchire Eranga Wijesinghe received his BSc degree in electrical engineering from Kyungpook National University, Daegu, Republic of Korea. Currently, he is a PhD researcher in the Electronics Engineering Department of Kyungpook National University, since 2014. His research interests are in the development of novel biomedical and biological imaging techniques based on optical coherence tomography and optical coherence microscopy for medical, agricultural, industrial, and entomological applications.