1. Rocco Vergallo

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    1. Mentioned In 48 Articles

    2. Interpretation of optical coherence tomography images : The Lancet

      Interpretation of optical coherence tomography images : The Lancet
      We read with great interest the Clinical Picture reported by Dennis Wong and colleagues (Feb 8, p e11) 1 who took advantage of the unprecedented resolution of optical coherence tomography (OCT) to identify the culprit lesion and guide coronary stenting in a patient with acute myocardial infarction. Over the last decade, OCT has become the method of choice to investigate the mechanisms responsible for acute coronary syndromes. 2 In this ...
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    3. Spatial Heterogeneity of Neoatherosclerosis, and its Relationship with Neovascularization and Adjacent Plaque Characteristics: Optical Coherence Tomography Study

      Spatial Heterogeneity of Neoatherosclerosis, and its Relationship with Neovascularization and Adjacent Plaque Characteristics: Optical Coherence Tomography Study
      ...hD Affiliations + Cardiology Division, Massachusetts General Hospital, Harvard Medical School, Boston, MA , * Rocco Vergallo, MD Affiliations + Cardiology Division, Massachusetts General Hospital, Harvard Medical School,...
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    4. Distinct Morphological Features of Ruptured Culprit Plaque for Acute Coronary Events Compared to those with Silent Rupture and Thin-Cap Fibroatheroma: a Combined Optical Coherence Tomography and Intravascular Ultrasound Study

      Distinct Morphological Features of Ruptured Culprit Plaque for Acute Coronary Events Compared to those with Silent Rupture and Thin-Cap Fibroatheroma: a Combined Optical Coherence Tomography and Intravascular Ultrasound Study
      Objectives To identify specific morphological characteristics of ruptured culprit plaques (RCP) responsible for acute events, and compare them with ruptured non-culprit plaques (RNCP) and non-ruptured thin-cap fibroatheroma (TCFA) in patients presenting with acute coronary syndromes (ACS). Background Non-ruptured TCFA and multiple ruptured plaques are detected in the same patients with ACS. It remains unknown whether certain morphological characteristics determine rupture of TCFA and subsequently result in ACS. Methods We analyzed ...
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    5. Comprehensive overview of definitions for optical coherence tomography-based plaque and stent analyses

      Comprehensive overview of definitions for optical coherence tomography-based plaque and stent analyses
      Optical coherence tomography (OCT) is the current state-of-the-art intracoronary imaging modality that allows visualization of detailed morphological characteristics of both atherosclerotic plaque and stent. So far, three expert review documents have been released for standardization of OCT image analysis. In the real world, a variety of definitions are being used by different groups and by different core laboratories to analyze OCT findings because of different clinical/procedural contexts in which ...
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    6. Pancoronary Plaque Vulnerability in Patients with Acute Coronary Syndrome and Ruptured Culprit Plaque: A Three-Vessel Optical Coherence Tomography Study

      Pancoronary Plaque Vulnerability in Patients with Acute Coronary Syndrome and Ruptured Culprit Plaque: A Three-Vessel Optical Coherence Tomography Study
      Background Recent studies described different clinical and underlying plaque characteristics between patients with and without plaque rupture presenting with acute coronary syndrome (ACS). In light of the systemic nature of atherosclerosis, we hypothesized that non-culprit plaques might also express different morphological features in these two groups of patients. Methods Thirty-eight patients with ACS who underwent 3-vessel optical coherence tomography (OCT) imaging were identified from the Massachusetts General Hospital OCT Registry ...
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    7. Features of Coronary Plaque in Patients with Metabolic Syndrome and Diabetes Mellitus Assessed by 3-vessel Optical Coherence Tomography

      Features of Coronary Plaque in Patients with Metabolic Syndrome and Diabetes Mellitus Assessed by 3-vessel Optical Coherence Tomography
      Background The pathophysiologic basis for the association between metabolic syndrome (MetS) and coronary artery disease is not well understood. We sought to characterize coronary plaques in patients with MetS using optical coherence tomography (OCT). Methods and Results We identified 451 coronary plaques from 171 subjects who underwent OCT imaging in three coronary arteries. Subjects were divided into 3 groups: diabetes mellitus (DM, n=77), MetS (n=35), and a control ...
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    8. Feature Of The Week 8/4/13: MGH OCT Registry Reports on In Vivo OCT Studies of Plaque Erosion and Calcified Nodule In Acute Coronary Syndrome

      Feature Of The Week 8/4/13: MGH OCT Registry Reports on In Vivo OCT Studies of Plaque Erosion and Calcified Nodule In Acute Coronary Syndrome
      Pathology studies reported that three most common causes of acute coronary syndrome (ACS) or sudden cardiac death are plaque rupture, plaque erosion and calcified nodules. The morphological and clinical characteristics of the underlying pathology of ACS, especially plaque erosion and calcified nodule, have never been well studied in vivo. Using optical coherence tomography, we found that plaque erosions are the substrate for ACS in 31% of patients and calcified nodules ...
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    9. Correlation Between Degree of Neointimal Hyperplasia and Incidence and Characteristics of Neoatherosclerosis as Assessed by Optical Coherence Tomography

      Correlation Between Degree of Neointimal Hyperplasia and Incidence and Characteristics of Neoatherosclerosis as Assessed by Optical Coherence Tomography
      ...lasia and Incidence and Characteristics of Neoatherosclerosis as Assessed by Optical Coherence Tomography * Rocco Vergallo, MD Affiliations + Cardiology Division, Massachusetts General Hospital, Harvard Medical School,...
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    10. In Vivo Diagnosis of Plaque Erosion and Calcified Nodule in Patients with Acute Coronary Syndrome by Intravascular Optical Coherence Tomography

      In Vivo Diagnosis of Plaque Erosion and Calcified Nodule in Patients with Acute Coronary Syndrome by Intravascular Optical Coherence Tomography
      ...^4, * Stanley Chia, MD, MRCP^5, * Harry Lowe, MBChB, PhD^6, * Koji Kato, MD, PhD^2, * Taishi Yonetsu, MD^2, * Rocco Vergallo, MD^2, * Sining Hu, MD^1^, ^2, * Jinwei Tian, MD, PhD^1^, ^2, * Hang Lee, PhD^7, * Seung-Jung P...
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    11. 31-45 of 48 « 1 2 3 4 »
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  2. About Rocco Vergallo

    Rocco Vergallo

    Rocco Vergallo  is a research fellow in the Cardiovascular Research Center of Massachusetts General Hospital. He received his MD in 2011 from the Catholic University of Rome and came to Mass General in July 2012 to work with Dr. Jang on the Mass General OCT Registry. His main research interests are investigating the relationship between OCT plaque characteristics and novel circulating biomarkers, and clarifying the mechanisms of plaque vulnerability.