1. Robin P. Choudhury

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    1. Mentioned In 7 Articles

    2. The influence of coronary plaque morphology assessed by optical coherence tomography on final microvascular function after stenting in patients with ST-elevation myocardial infarction

      The influence of coronary plaque morphology assessed by optical coherence tomography on final microvascular function after stenting in patients with ST-elevation myocardial infarction
      Objectives: The index of microcirculatory resistance (IMR) provides a reproducible assessment of the status of coronary microvasculature in patients with ST-elevation myocardial infarction (STEMI). Frequency-domain optical coherence tomography (FD-OCT) enables detailed assessment of the morphology of coronary plaque. We sought to determine the influence of the initial culprit coronary plaque anatomy within the infarct-related artery on IMR after stenting in STEMI. Patients and methods: In 25 STEMI patients IMR was ...
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    3. Absolute measurement of subnanometer scale vibration of cochlear partition of an excised guinea pig cochlea using spectral-domain phase-sensitive optical coherence tomography

      Absolute measurement of subnanometer scale vibration of cochlear partition of an excised guinea pig cochlea using spectral-domain phase-sensitive optical coherence tomography
      Direct measurement of absolute vibration parameters from different locations within the mammalian organ of Corti is crucial for understanding the hearing mechanics such as how sound propagates through the cochlea and how sound stimulates the vibration of various structures of the cochlea, namely, basilar membrane (BM), recticular lamina, outer hair cells and tectorial membrane (TM). In this study we demonstrate the feasibility a modified phase-sensitive spectral domain optical coherence tomography ...
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    4. Feature Of The Week 1/1/12: University of Oxford Investigates Molecular Imaging with OCT Using Ligand-Conjugated Microparticles that Detect Activated Endothelial Cells

      Feature Of The Week 1/1/12: University of Oxford Investigates Molecular Imaging with OCT Using Ligand-Conjugated Microparticles that Detect Activated Endothelial Cells
      Optical Coherence Tomography (OCT) is a high resolution imaging technique used to assess superficial atherosclerotic plaque morphology. Utility of OCT may be enhanced by contrast agents targeting molecular mediators of inflammation. We have previously described the use of microparticles of iron oxide (MPIO) as a contrast agent for MRI that can be targeted to molecular mediators of inflammation via conjugation of specific antibodies. 1 and 4.5 μm diameter MPIO ...
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    5. Molecular imaging with optical coherence tomography using ligand-conjugated microparticles that detect activated endothelial cells: Rational design through target quantification

      Molecular imaging with optical coherence tomography using ligand-conjugated microparticles that detect activated endothelial cells: Rational design through target quantification
      Objectives Optical coherence tomography (OCT) is a high resolution imaging technique used to assess superficial atherosclerotic plaque morphology. Utility of OCT may be enhanced by contrast agents targeting molecular mediators of inflammation. Methods and results Microparticles of iron oxide (MPIO; 1 and 4.5μm diameter) in suspension were visualized and accurately quantified using a clinical optical coherence tomography system. Bound to PECAM-1 on a plane of cultured endothelial cells under ...
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  2. About Robin P. Choudhury

    Robin Choudhury,  Wellcome Trust Clinical Research Fellow at the University of Oxford. Department of Cardiovascular Medicine Level 5 John Radcliffe Hospital. Robin Choudhury qualified in medicine at the University of Oxford (1992: BA, BM, BCh; 2002: DM) with postgraduate training in London (Royal Brompton & Hammersmith). In 1999 he moved to Mount Sinai School of Medicine, New York, working in (1) the basics science of vascular disease (effects of HDL-c on atherosclerosis progression / regression, with Professor Edward Fisher) and (2) in the Imaging Science Laboratory (Professors Valentin Fuster & Zahi Fayad) using MRI to phenotype experimental atherosclerosis. He returned to Oxford in 2001 and is currently a Wellcome Trust Intermediate Clinical Fellow and Honorary Consultant Cardiologist to the John Radcliffe Hospital. He serves on the Councils of The Society for Atherosclerosis Imaging and the Royal Society of Medicine Section on Lipids in Clinical Medicine. Since 2005, he has been a London Technology Network Business Fellow, providing an interface between industry and Cardiovascular Medicine.