1. Robert Schmitt

    0 Comments Leave a Comment

    1-17 of 17
    1. Mentioned In 17 Articles

    2. Polarization-sensitive optical coherence tomography-based imaging, parameterization, and quantification of human cartilage degeneration

      Polarization-sensitive optical coherence tomography-based imaging, parameterization, and quantification of human cartilage degeneration
      Polarization-sensitive optical coherence tomography (PS-OCT) is a light-based, high-resolution, real-time, noninvasive, and nondestructive imaging modality yielding quasimicroscopic cross-sectional images of cartilage. As yet, comprehensive parameterization and quantification of birefringence and tissue properties have not been performed on human cartilage. PS-OCT and algorithm-based image analysis were used to objectively grade human cartilage degeneration in terms of surface irregularity, tissue homogeneity, signal attenuation, as well as birefringence coefficient and band width, height ...
      Read Full Article
    3. Towards Optical Coherence Tomography-Based Elastographic Evaluation of Human Cartilage

      Towards Optical Coherence Tomography-Based Elastographic Evaluation of Human Cartilage
      Optical Coherence Tomography (OCT) is an imaging technique that allows the surface and subsurface evaluation of semitransparent tissues by generating microscopic cross-sectional images in real time, to millimeter depths and at micrometer resolutions. As the differentiation of cartilage degeneration remains diagnostically challenging to standard imaging modalities, an OCT- and MRI-compatible indentation device for the assessment of cartilage functional properties was developed and validated in the present study. After describing the ...
      Read Full Article
    4. 3D Human cartilage surface characterization by optical coherence tomography

      3D Human cartilage surface characterization by optical coherence tomography
      Early diagnosis and treatment of cartilage degeneration is of high clinical interest. Loss of surface integrity is considered one of the earliest and most reliable signs of degeneration, but cannot currently be evaluated objectively. Optical Coherence Tomography (OCT) is an arthroscopically available light-based non-destructive real-time imaging technology that allows imaging at micrometre resolutions to millimetre depths. As OCT-based surface evaluation standards remain to be defined, the present study investigated the ...
      Read Full Article
    5. Evaluation of Single-Impact-Induced Cartilage Degeneration by Optical Coherence Tomography

      Evaluation of Single-Impact-Induced Cartilage Degeneration by Optical Coherence Tomography
      Posttraumatic osteoarthritis constitutes a major cause of disability in our increasingly elderly population. Unfortunately, current imaging modalities are too insensitive to detect early degenerative changes of this disease. Optical coherence tomography (OCT) is a promising nondestructive imaging technique that allows surface and subsurface imaging of cartilage, at near-histological resolution, and is principally applicable in vivo during arthroscopy. Thirty-four macroscopically normal human cartilage-bone samples obtained from total joint replacements were subjected ...
      Read Full Article
    6. Optical coherence tomography-based parameterization and quantification of articular cartilage surface integrity

      Optical coherence tomography-based parameterization and quantification of articular cartilage surface integrity
      Loss of articular cartilage surface integrity is considered the earliest sign of osteoarthritis; however, its reliable detection has not been established by clinical routine diagnostics. This study comprehensively assesses a set of 11 algorithm-based 2-D Optical Coherence Tomography roughness parameters and investigates their clinical impact. Histology and manual irregularity quantification of 105 human cartilage samples with variable degeneration served as reference. The majority of parameters revealed a close-to-linear correlation with ...
      Read Full Article
    7. Feature Of The Week 03/01/15: Three-dimensional Imaging and Analysis of Human Cartilage Degeneration Using Optical Coherence Tomography

      Feature Of The Week 03/01/15: Three-dimensional Imaging and Analysis of Human Cartilage Degeneration Using Optical Coherence Tomography
      Optical Coherence Tomography (OCT) is an evolving imaging technology allowing non-destructive imaging of cartilage tissue at near-histological resolution. In this study, the diagnostic value of 3-D OCT in comparison to 2-D OCT in the comprehensive grading of human cartilage degeneration is investigated. In total, 53 human osteochondral samples were harvested. The imaging was performed by obtaining a single B-scan image (2-D OCT) and by collecting 100 consecutive B-scan images to ...
      Read Full Article
    8. Feature of the Week 10/26/14: 3D Polymer Weld Seam Characterization Based on OCT Laser Transmission Welding Applications

      Feature of the Week 10/26/14: 3D Polymer Weld Seam Characterization Based on OCT Laser Transmission Welding Applications
      ...smission welding will be presented. For more information see recent Article . Courtesy Guilherme Mallmann and Robert Schmitt from RWTH Aachen University . Plastics have low weight but a high weight to strength ratio and ...
      Read Full Article
    9. 3D Polymer Weld Seam Characterization Based on Optical Coherence Tomography for Laser Transmission Welding Applications

      3D Polymer Weld Seam Characterization Based on Optical Coherence Tomography for Laser Transmission Welding Applications
      Laser transmission welding is an established single-stage plastic joining process, which enables hermetically sealed joints under the workpiece surface. The process requires joining partners with proper degrees of transmission and absorption to the processing wavelength. For reaching a stable process an in-process quality assurance is very valuable. Current monitoring systems have a limited usage, as no quantitative information of the weld itself is obtained without its destruction. In medical and ...
      Read Full Article
    10. Optical coherence tomography investigation of growth cycles of engineered skin tissue

      Optical coherence tomography investigation of growth cycles of engineered skin tissue
      Engineered skin tissues are widely used in dermatological, pharmacological and toxicological studies and as autologous transplants in wound healing. Due to the high demand for artificial skin equivalents, there is a need for an automation of the manual production process to achieve a high-grade product. Thus, non-invasive monitoring of engineered tissue during the growth cycles is of major significance to understand and consequently improve the growth characteristics of in vitro ...
      Read Full Article
    11. Non-destructive detection of defects in artificial skin tissue by optical coherence tomography

      The application of optical coherence tomography OCT in tissue engineering facilities offers great potential for the automated detection of defects or inhomogeneities in tissue products. This non-invasive and non-destructive measurement technique enables the high speed generation of two dimensional cross sections of tissue with micron resolution. The integration of an OCT device into a tissue production facility allows the monitoring and quality control of tissue engineering products. By the selective ...
      Read Full Article
    12. 1-17 of 17
  1. Categories

    1. Applications:

      Art, Cardiology, Dentistry, Dermatology, Developmental Biology, Gastroenterology, Gynecology, Microscopy, NDE/NDT, Neurology, Oncology, Ophthalmology, Other Non-Medical, Otolaryngology, Pulmonology, Urology
    2. Business News:

      Acquisition, Clinical Trials, Funding, Other Business News, Partnership, Patents
    3. Technology:

      Broadband Sources, Probes, Tunable Sources
    4. Miscellaneous:

      Jobs & Studentships, Student Theses, Textbooks
  2. About Robert Schmitt

    Robert Schmitt

    Robert Schmitt is Head of the Chair of Metrology and Quality Management and member of the board of directors for the Laboratory for Machine Tools and Production Engineering WZL of the RWTH Aachen University. He is also Head of the Department Production Metrology and