1. Robert J. Zawadzki

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    1. Mentioned In 113 Articles

    2. Post-Doc Position for biomedical engineer / vision scientist in the UC Davis EyePod - Small Animal Retinal Imaging Laboratory at University of California, Davis

      Explore Optical Coherence Tomography News Jobs & Studentships
      Post-Doc Position for biomedical engineer / vision scientist in the UC Davis EyePod - Small Animal Retinal Imaging Laboratory at University of California, Davis
      ...he names of 3 references. Inquires by e-mail (rjzawadzki@ucdavis.edu) are welcome before formal application. Robert J. Zawadzki https://scholar.google.com/citations?user=LfflHRgAAAAJhl=enoi=ao Applications are invited f...
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      Mentions: UC Davis Robert J. Zawadzki

    3. Kilohertz retinal FF-SS-OCT and flood imaging with hardware-based adaptive optics

      Explore OSA | OSA Publishing Ophthalmology
      Kilohertz retinal FF-SS-OCT and flood imaging with hardware-based adaptive optics
      A retinal imaging system was designed for full-field (FF) swept-source (SS) optical coherence tomography (OCT) with cellular resolution. The system incorporates a real-time adaptive optics (AO) subsystem and a very high-speed CMOS sensor, and is capable of acquiring volumetric images of the retina at rates up to 1 kHz. While digital aberration correction (DAC) is an attractive potential alternative to AO, it has not yet been shown to provide resolution ...
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      Mentions: UC Davis Robert J. Zawadzki Ravi S. Jonnal

    4. Visible light OCT improves imaging through a highly scattering retinal pigment epithelial wall

      Explore OSA | OSA Publishing
      Visible light OCT improves imaging through a highly scattering retinal pigment epithelial wall
      Here we provide a counter-example to the conventional wisdom in biomedical optics that longer wavelengths aid deeper imaging in tissue. Specifically, we investigate visible light optical coherence tomography of Bruchs membrane (BM) in the non-pathologic eyes of humans and two mouse strains. Surprisingly, we find that shorter visible wavelengths improve the visualization of BM in pigmented eyes, where it is located behind a highly scattering layer of melanosomes in the ...
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      Mentions: Vivek J. Srinivasan UC Davis Robert J. Zawadzki

    5. Optoretinogram: optical measurement of human cone and rod photoreceptor responses to light

      Explore OSA | OSA Publishing Ophthalmology
      Optoretinogram: optical measurement of human cone and rod photoreceptor responses to light
      Noninvasive, objective measurement of rod function is as significant as that of cone function, and for retinal diseases such as retinitis pigmentosa and age-related macular degeneration, rod function may be a more sensitive biomarker of disease progression and efficacy of treatment than cone function. Functional imaging of single human rod photoreceptors, however, has proven difficult because their small size and rapid functional response pose challenges for the resolution and speed ...
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      Mentions: John S. Werner UC Davis Robert J. Zawadzki

    7. Temporal speckle-averaging of optical coherence tomography volumes for in-vivo cellular resolution neuronal and vascular retinal imaging

      Explore SPIE Digital Library Ophthalmology
      Temporal speckle-averaging of optical coherence tomography volumes for in-vivo cellular resolution neuronal and vascular retinal imaging
      It has been recently demonstrated that structures corresponding to the cell bodies of highly transparent cells in the retinal ganglion cell layer could be visualized noninvasively in the living human eye by optical coherence tomography (OCT) via temporal averaging. Inspired by this development, we explored the application of volumetric temporal averaging in mice, which are important models for studying human retinal diseases and therapeutic interventions. A general framework of temporal ...
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      Mentions: UC Davis Robert J. Zawadzki Pengfei Zhang

    8. Coextensive synchronized SLO-OCT with adaptive optics for human retinal imaging

      Explore OSA | OSA Publishing Ophthalmology
      Coextensive synchronized SLO-OCT with adaptive optics for human retinal imaging
      We describe the details of a multimodal retinal imaging system which combines adaptive optics (AO) with an integrated scanning light ophthalmoscopy (SLO) and optical coherence tomography (OCT) imaging system. The OCT subsystem consisted of a swept-source, Fourier-domain mode-locked (FDML) laser, with a very high A-scan rate (1.6 MHz), whose beam was raster scanned on the retina by two scannersone resonant scanner and one galvanometer. The high sweep rate of ...
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      Mentions: John S. Werner Robert J. Zawadzki UCSD

    9. Directional optical coherence tomography reveals melanin concentration-dependent scattering properties of retinal pigment epithelium

      Explore SPIE Digital Library Ophthalmology
      Directional optical coherence tomography reveals melanin concentration-dependent scattering properties of retinal pigment epithelium
      Optical coherence tomography (OCT) is a powerful tool in ophthalmology that provides in vivo morphology of the retinal layers and their light scattering properties. The directional (angular) reflectivity of the retinal layers was investigated with focus on the scattering from retinal pigment epithelium (RPE). The directional scattering of the RPE was studied in three mice strains with three distinct melanin concentrations: albino (BALB/c), agouti (129S1/SvlmJ), and strongly pigmented ...
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      Mentions: Oregon Health & Science University UC Davis Robert J. Zawadzki

    10. Feature Of The Week 03/01/2019: Functional Retina lmaging using Adaptive Optics Swept-Source OCT at 1.6 MHz

      Explore Optical Coherence Tomography News Ophthalmology
      Feature Of The Week 03/01/2019: Functional Retina lmaging using Adaptive Optics Swept-Source OCT at 1.6 MHz
      Functional assessment of the retina is a critical part of both clinical ophthalmology and vision research. Several techniques exist for measuring retinal function, such as Visual acuity/contrast sensitivity tests, Psychophysics and ERG (Electroretinogram and multifocal Electroretinogram). However, these approaches have important limitations, poor spatial resolution, slightly invasive; long duration of tests. There is great excitement about emerging noninvasive approaches to measuring retinal function, both from clinical and basic scientific ...
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      Mentions: John S. Werner UC Davis Robert J. Zawadzki

    11. Functional retinal imaging using adaptive optics swept-source OCT at 1.6  MHz

      Explore OSA | OSA Publishing
      Functional retinal imaging using adaptive optics swept-source OCT at 1.6  MHz
      Objective optical assessment of photoreceptor function may permit earlier diagnosis of retinal disease than current methods such as perimetry, electrophysiology, and clinical imaging. In this work, we describe an adaptive optics (AO) optical coherence tomography (OCT) system designed to measure functional responses of single cones to visible stimuli. The OCT subsystem consisted of a raster-scanning Fourier-domain mode-locked laser that acquires A scans at 1.64 MHz with a center wavelength ...
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      Mentions: John S. Werner Robert J. Zawadzki UCSD

    13. Megahertz-rate optical coherence tomography angiography improves the contrast of the choriocapillaris and choroid in human retinal imaging

      Explore OSA | OSA Publishing Ophthalmology
      Megahertz-rate optical coherence tomography angiography improves the contrast of the choriocapillaris and choroid in human retinal imaging
      Angiographic imaging of the human eye with optical coherence tomography (OCT) is becoming an increasingly important tool in the scientific investigation and clinical management of several blinding diseases, including age-related macular degeneration and diabetic retinopathy. We have observed that OCT angiography (OCTA) of the human choriocapillaris and choroid with a 1.64 MHz A-scan rate swept-source laser yields higher contrast images as compared to a slower rate system operating at ...
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      Mentions: John S. Werner Nicolaus Copernicus University UC Davis

    14. Intraframe motion correction for raster-scanned adaptive optics images using strip-based cross-correlation lag biases

      Explore Journals | PLOS Ophthalmology
      Intraframe motion correction for raster-scanned adaptive optics images using strip-based cross-correlation lag biases
      In retinal raster imaging modalities, fixational eye movements manifest as image warp, where the relative positions of the beam and retina change during the acquisition of single frames. To remove warp artifacts, strip-based registration methodsin which fast-axis strips from target images are registered to a reference framehave been applied in adaptive optics (AO) scanning light ophthalmoscopy (SLO) and optical coherence tomography (OCT). This approach has enabled object tracking and frame ...
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      Mentions: Thorlabs Dalsa Superlum

    15. Aperture Phase Modulation with Adaptive Optics: A Novel Approach for Speckle Reduction and Structure Extraction in Optical Coherence Tomography

      Explore bioRxiv.org Ophthalmology
      Aperture Phase Modulation with Adaptive Optics: A Novel Approach for Speckle Reduction and Structure Extraction in Optical Coherence Tomography
      Speckle is an inevitable consequence of the use of coherent light in optical coherence tomography (OCT), and often acts as noise that obscures micro-structures of biological tissue. We here present a novel method of suppressing speckle noise intrinsically compatible with adaptive optics (AO) in OCT system: by modulating the phase inside the imaging system pupil aperture with a segmented deformable mirror, thus producing minor perturbations in the point spread function ...
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      Mentions: Oregon Health & Science University UC Davis Robert J. Zawadzki
    17. 1-15 of 113 1 2 3 4 5 6 7 8 »
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  4. About Robert J. Zawadzki

    Robert J. Zawadzki

    Robert J. Zawadzki (b.1975) received his MSc in Medical Physics from Nicholas Copernicus University (NCU), Torun, Poland under Prof. Andrzej Kowalczyk  supervision. He received his PhD in natural sciences from Technical University of Vienna, Vienna, Austria based on his work in the field of OCT at Medical Physics Institute, University of Vienna under Prof. Adolf F. Fercher supervision.

    Presently he has a faculty position of assistant professional research in Dept. of Ophthalmology and Vision Science at University of California Davis, Sacramento, CA USA and works together with Prof. John S. Werner in his Vision Science and Advanced Retinal Imaging Laboratory. His research interest includes development and application of novel instrumentation for high resolution in-vivo retinal imaging. This includes Adaptive Optics (AO), Optical Coherence Tomography (OCT), Scanning Laser Ophthalmoscopy (SLO) and its combination.

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