1. Robert A. Huber

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    1. Mentioned In 99 Articles

    2. Simultaneous morphological and flow imaging enabled by megahertz intravascular Doppler optical coherence tomography

      Explore IEEE Xplore Cardiology
      Simultaneous morphological and flow imaging enabled by megahertz intravascular Doppler optical coherence tomography
      We demonstrate three-dimensional intravascular flow imaging compatible with routine clinical image acquisition workflow by means of megahertz (MHz) intravascular Doppler Optical Coherence Tomography (OCT). The OCT system relies on a 1.1 mm diameter motorized imaging catheter and a 1.5 MHz Fourier Domain Mode Locked (FDML) laser. Using a post processing method to compensate the drift of the FDML laser output, we can resolve the Doppler phase shift between ...
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      Mentions: Robert A. Huber Gijs van Soest Anton F. W. van der Steen

    3. Motorized capsule for shadow-free OCT imaging and synchronous beam control

      Explore OSA | OSA Publishing Gastroenterology , Probes
      Motorized capsule for shadow-free OCT imaging and synchronous beam control
      We demonstrate a tethered motorized capsule for unobstructed optical coherence tomography (OCT) imaging of the esophagus. By using a distal reflector design, we avoided the common shadow artifact induced by the motor wires. A synchronous driving technique features three types of beam-scanning modes of the capsule, i.e., circumferential beam scanning, localized beam scanning, and accurate beam positioning. We characterized these three modes and carried out ex vivo imaging experiments ...
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      Mentions: Brett E. Bouma Massachusetts General Hospital Harvard University

    4. OptoRes presents world-record 3 MHz swept laser at SPIE BiOS / Photonics West in San Francisco

      Explore Optical Coherence Tomography News Other Business News , Tunable Sources
      OptoRes presents world-record 3 MHz swept laser at SPIE BiOS / Photonics West in San Francisco
      ...on. Optores GmbH is a privately held company based in Munich, Germany. It was founded in 2013 based on Prof. Robert Huber’s groundbreaking work on Fourier-domain mode-locked lasers and ultrafast OCT, for which he was aw...
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      Mentions: James G. Fujimoto Robert A. Huber University of Lübeck

    5. High-speed fiber scanning endoscope for volumetric multi-megahertz optical coherence tomography

      Explore OSA | OSA Publishing Probes
      High-speed fiber scanning endoscope for volumetric multi-megahertz optical coherence tomography
      We present a forward-viewing fiber scanning endoscope (FSE) for high-speed volumetric optical coherence tomography (OCT). The reduction in size of the probe was achieved by substituting the focusing optics by an all-fiber-based imaging system which consists of a combination of scanning single-mode fibers, a glass spacer, made from a step-index multi-mode fiber, and a gradient-index fiber. A lateral resolution of 11 m was achieved at a working distance of 1 ...
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      Mentions: Robert A. Huber Gereon Hüttmann University of Lübeck

    6. Ultra low noise Fourier domain mode locked laser for high quality megahertz optical coherence tomography

      Explore OSA | OSA Publishing Tunable Sources
      Ultra low noise Fourier domain mode locked laser for high quality megahertz optical coherence tomography
      We investigate the origin of high frequency noise in Fourier domain mode locked (FDML) lasers and present an extremely well dispersion compensated setup which virtually eliminates intensity noise and dramatically improves coherence properties. We show optical coherence tomography (OCT) imaging at 3.2 MHz A-scan rate and demonstrate the positive impact of the described improvements on the image quality. Especially in highly scattering samples, at specular reflections and for strong ...
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      Mentions: Robert A. Huber University of Lübeck Technical University of Munich

    7. High-resolution retinal swept source optical coherence tomography with an ultra-wideband Fourier-domain mode-locked laser at MHz A-scan rates

      Explore OSA | OSA Publishing Ophthalmology , Tunable Sources
      High-resolution retinal swept source optical coherence tomography with an ultra-wideband Fourier-domain mode-locked laser at MHz A-scan rates
      We present a new 1060 nm Fourier domain mode locked laser (FDML laser) with a record 143 nm sweep bandwidth at 2∙ 417 kHz = 834 kHz and 120 nm at 1.67 MHz, respectively. We show that not only the bandwidth alone, but also the shape of the spectrum is critical for the resulting axial resolution, because of the specific wavelength-dependent absorption of the vitreous. The theoretical limit of our ...
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      Mentions: Robert A. Huber University of Lübeck Tom Pfeiffer

    8. Swept source OCT system and method with phase-locked detection

      Explore uspto.gov Patents , Tunable Sources
      Swept source OCT system and method with phase-locked detection
      A swept source OCT system and related method are disclosed. The system comprises a control device for operating a tunable light source in response to an electronic sweep control signal such that the tunable light source carries out wave length sweeps with a repetition rate f.sub.sweep, which depends on the frequency of the sweep control signal. The system further comprises a detection device for the time-resolved detection of ...
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      Mentions: Robert A. Huber Wolfgang Wieser Thomas Klein

    9. Feature Of The Week 09/10/2017: Thermo-elastic Optical Coherence Tomography

      Explore Optical Coherence Tomography News
      Feature Of The Week 09/10/2017: Thermo-elastic Optical Coherence Tomography
      The conventional OCT image contrast is derived from elastic scattering, and shows the internal structure of the sample. The determination of the tissue type in OCT images usually depends on the interpretation by the image reader. More accurate tissue type contrast may be achieved by new OCT-based imaging modalities, with sensitivity to other physical parameters than scattering alone. Phase-sensitive OCT can detect tissue motion on nanometer-to- micrometer length scales using ...
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      Mentions: Robert A. Huber Delft University of Technology Chinese Academy of Sciences

    10. Thermo-elastic optical coherence tomography

      Explore OSA | OSA Publishing
      Thermo-elastic optical coherence tomography
      The absorption of nanosecond laser pulses induces rapid thermo-elastic deformation in tissue. A sub-micrometer scale displacement occurs within a few microseconds after the pulse arrival. In this Letter, we investigate the laser-induced thermo-elastic deformation using a 1.5 MHz phase-sensitive optical coherence tomography (OCT) system. A displacement image can be reconstructed, which enables a new modality of phase-sensitive OCT, called thermo-elastic OCT. An analysis of the results shows that the ...
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      Mentions: Robert A. Huber Delft University of Technology Chinese Academy of Sciences

    11. Method for reducing the dimensionality of a spatially registered signal derived from the optical properties of a sample, and device therefor

      Explore uspto.gov Patents
      Method for reducing the dimensionality of a spatially registered signal derived from the optical properties of a sample, and device therefor
      At least one embodiment of the method is designed to create a two-dimensional image of a three-dimensional sample. The method comprises the following steps: provision of a wave-length-tunable light source (1) that emits primary radiation (P) with wavelengths that vary over time; sampling of location points of the sample (2) with the primary radiation (P); collection of secondary radiation (S), wherein the secondary radiation (S) is a part of the ...
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      Mentions: Robert A. Huber Wolfgang Wieser Thomas Klein

    13. INTRAPAPILLARY PROLIFERATION IN OPTIC DISK PITS: Clinical Findings and Time-Related Changes

      Explore LWW Online Ophthalmology
      INTRAPAPILLARY PROLIFERATION IN OPTIC DISK PITS: Clinical Findings and Time-Related Changes
      Purpose: To investigate the structural changes of intrapapillary proliferations associated with optic disk pits (ODPs) and optic disk pit maculopathy (ODP-M) using enhanced depth-spectral domain-optical coherence tomography (SD-EDI-OCT) and megahertz optical coherence tomography (MHz-OCT). Methods: Sixteen eyes of patients with ODPs were studied. Papillary and peripapillary areas were repeatedly examined with SD-EDI-OCT over time. To evaluate swept-source OCT, some of the patients additionally received MHz-OCT-imaging. Results: MHz-OCT or SD-EDI images ...
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      Mentions: Robert A. Huber Wolfgang Wieser University of Lübeck

    14. Feature tracking for automated volume of interest stabilization on 4D-OCT images

      Explore Conference Proceedings
      Feature tracking for automated volume of interest stabilization on 4D-OCT images
      A common representation of volumetric medical image data is the triplanar view (TV), in which the surgeon manually selects slices showing the anatomical structure of interest. In addition to common medical imaging such as MRI or computed tomography, recent advances in the field of optical coherence tomography (OCT) have enabled live processing and volumetric rendering of four-dimensional images of the human body. Due to the region of interest undergoing motion ...
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      Mentions: Robert A. Huber University of Lübeck University of Hannover

    15. Analysis of FDML lasers with meter range coherence

      Explore Conference Proceedings Tunable Sources
      Analysis of FDML lasers with meter range coherence
      FDML lasers provide sweep rates in the MHz range at wide optical bandwidths, making them ideal sources for high speed OCT. Recently, at lower speed, ultralong-range swept-source OCT has been demonstrated using a tunable vertical cavity surface emitting laser (VCSEL) and also using a Vernier-tunable laser. These sources provide relatively high sweep rates and meter range coherence lengths. In order to achieve similar coherence, we developed an extremely well dispersion ...
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      Mentions: Robert A. Huber Wolfgang Wieser University of Lübeck

    16. High-speed OCT light sources and systems [Invited]

      Explore OSA | OSA Publishing
      High-speed OCT light sources and systems [Invited]
      Imaging speed is one of the most important parameters that define the performance of optical coherence tomography (OCT) systems. During the last two decades, OCT speed has increased by over three orders of magnitude. New developments in wavelength-swept lasers have repeatedly been crucial for this development. In this review, we discuss the historical evolution and current state of the art of high-speed OCT systems, with focus on wavelength swept light ...
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      Mentions: Robert A. Huber University of Lübeck Thomas Klein
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  4. About Robert A. Huber

    Robert A. Huber

    Robert Huber the studied general physics at the Ludwig-Maximilians-Universität (LMU) in Munich, Germany, where he received his PhD for work on ultrafast electron transfer processes at dye-semiconductor surfaces in 2002. From 2002-2003 Robert Huber worked as Postdoc at the Institute of Physical and Theoretical Chemistry at the J. W. Goethe University in Frankfurt. From 2003 to 2006 he joined the group of Prof. J. G. Fujimoto at the Massachusetts Institute of Technology as postdoctoral associate. Since 2007 he leads an independent research group at the LMU Munich in the Emmy Noether program of the DFG and the ERC starting grant program of the European Union. His group was partner in the European consortium “FUN-OCT”. Robert Huber coauthored more than 90 peer reviewed publications and holds more than 6 patents. In 2003 he received the Albert-Weller award from the German Chemical Society for an outstanding PhD thesis, in 2008 he received the Rudolf-Kaiser for his work on femtosecond spectroscopy and the development of Fourier domain mode locked lasers. In 2011 and 2012 he was ranked amongst the top 40 young talents in the field of science in Germany by the business magazine "Capital". Since September 2013 Robert Huber is a professor for biomedical imaging at the Institute of Biomedical Optics at the University zu Lübeck.

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