1. Reginald Birngruber

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    1. Mentioned In 10 Articles

    2. Simple approach for aberration-corrected OCT imaging of the human retina

      Simple approach for aberration-corrected OCT imaging of the human retina
      Aberration-corrected imaging of human photoreceptor cells, whether hardware or software based, presently requires a complex and expensive setup. Here we use a simple and inexpensive off-axis full-field time-domain optical coherence tomography (OCT) approach to acquire volumetric data of an in vivo human retina. Full volumetric data are recorded in 1.3 s. After computationally correcting for aberrations, single photoreceptor cells were visualized. In addition, the numerical correction of ametropia is ...
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    3. In-vivo retinal imaging with off-axis full-field time-domain optical coherence tomography

      In-vivo retinal imaging with off-axis full-field time-domain optical coherence tomography
      With a simple setup, mainly composed of a low coherence light source and a camera, full-field optical coherence tomography (FF-OCT) allows volumetric tissue imaging. However, fringe washout constrains its use in retinal imaging. Here, we present a novel motion-insensitive approach to FF-OCT, which introduces path-length differences between the reference and the sample light in neighboring pixels using an off-axis reference beam. The temporal carrier frequency in scanned time-domain OCT is ...
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    4. Device with an OCT system for examining and treating living tissue by means of heating of the tissue by absorbing electromagnetic radiation

      Device with an OCT system for examining and treating living tissue by means of heating of the tissue by absorbing electromagnetic radiation
      A device for examining or treating living tissue by means of local heating of the tissue by absorbing electromagnetic radiation, with at least one radiation source emitting electromagnetic radiation, a control unit for controlling the irradiation parameters of the radiation source, and at least one FD-OCT apparatus with a light source emitting a measurement light for illuminating that tissue region in which the electromagnetic radiation is absorbed by the tissue ...
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    5. Validation of two-dimensional and three-dimensional measurements of subpleural alveolar size parameters by optical coherence tomography

      Validation of two-dimensional and three-dimensional measurements of subpleural alveolar size parameters by optical coherence tomography
      Optical coherence tomography (OCT) has been increasingly used for imaging pulmonary alveoli. Only a few studies, however, have quantified individual alveolar areas, and the validity of alveolar volumes represented within OCT images has not been shown. To validate quantitative measurements of alveoli from OCT images, we compared the cross-sectional area, perimeter, volume, and surface area of matched subpleural alveoli from microcomputed tomography (micro-CT) and OCT images of fixed air-filled swine ...
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    6. Imaging of photothermal tissue expansion via phase sensitive optical coherence tomography

      Imaging of photothermal tissue expansion via phase sensitive optical coherence tomography
      Phase sensitive OCT enables the measurement of thermal expansion in laser irradiated material at high lateral and temporal resolution. In principle, a calculation of the 3D temperature distribution and its temporal evolution should be possible by evaluating the local expansion. This could be utilized for a non-invasive and very fast temperature measurement, e.g. to realize an online dosimetry for photocoagulation. The possibilities of quantitative investigations at high axial and ...
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    7. Effects on Choroidal Neovascularization after Anti-VEGF Upload Using Intravitreal Ranibizumab, as Determined by Spectral Domain-Optical Coherence Tomography

      ... as Determined by Spectral Domain-Optical Coherence Tomography Carsten Framme,^1^,2 Georgios Panagakis,^1 and Reginald Birngruber^3 ^From the ^1University Eye Hospital, Regensburg, Germany; ^the ^2University Eye Hospital...
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    8. Effects on Choroidal Neovascularizations after Anti-VEGF Upload Using Intravitreal Ranibizumab as Determined by Spectral Domain Optical Coherence Tomography

      ...mab as Determined by Spectral Domain Optical Coherence Tomography Carsten Framme,^1 Georgios Panagakis,^2 and Reginald Birngruber^3 ^^1Department of Ophthalmology, University of Regensburg, Regensburg, Germany^ ^2Depar...
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    9. Process and arrangement for examining a section of the eye

      Systems, methods, and apparatus are provided for deriving the relative position of an eye by tracking a boundary of the eye such as the limbus (i.e., the interface between the white sclera and the colored iris). A technique for tracking the position of the eye of patient comprises directing light to an annular region of the eye between the sclera and the iris and receiving reflected light from that ...
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  2. About Reginald Birngruber

    Reginald Birngruber

    Reginald Birngruber was from 1 January 1992 to 31 December 2010 Managing Director and Head of Research of the Medical Laser Center Lübeck and led by 01 January 2005 to 31 August 2010, the Institute of Biomedical Optics at the University of Luebeck as a director. Since 1992 he is professor of medical biophysics at the Medical University of Lübeck (UZL). In his academic career, Reginald Birngruber held as a lecturer in Medical Biophysics at the Ludwig-Maximilians-University Munich and the (UZL), as a visiting lecturer and professor of ophthalmology and dermatology at Harvard University, Boston, MA, and as a visiting professor at the Massachusetts Institute of Technology (MIT) lectures in the fields of laser-and photo-medicine, optics, and laser safety ohthalmologische.