1. Raju Poddar

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    1. Mentioned In 18 Articles

    2. Real-time assessment and characterization of immobilized lipase onto a natural matrix and qualitative reaction kinetic studies using swept-source optical coherence tomography

      Real-time assessment and characterization of immobilized lipase onto a natural matrix and qualitative reaction kinetic studies using swept-source optical coherence tomography
      The current study presents a method based on Optical Coherence Tomography (OCT) for non-destructive, real-time analysis and portrayal of immobilization efficacy for lipase on a natural matrix namely, eggshell. Subsequently, qualitative biochemical reaction kinetics of immobilized lipase was also studied. Successful immobilization of lipase on eggshell was confirmed by the presence of a clear peak in A scan of OCT image. From immobilization kinetics it is clearly observed that the ...
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    3. Synthesis of NaGdF4:Er3+/Yb3+ Upconversion Particles as Exogenous Contrast Agent for Swept-Source Optical Coherence Tomography: In vitro Animal Tissue Imaging

      Synthesis of NaGdF4:Er3+/Yb3+ Upconversion Particles as Exogenous Contrast Agent for Swept-Source Optical Coherence Tomography: In vitro Animal Tissue Imaging
      Swept-source optical coherence tomography (SSOCT) is a non-contact, non-invasive bioimaging tool that usesvarious probes to get high contrast images. Rare-earth based upconversion particles (UCPs) providea uniqueplatform to enhance the capabilities of bioimaging techniques. The UCPs can act as contrast enhancers for SSOCT with additional optical functionality and hence in this work upconversion emission optimized PVP/NaGdF4:Er3+/Yb3+UCPs were synthesized and then injected to chicken breast tissues to enhance ...
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    4. In Vitro Imaging of Animal Tissue with Upconversion Nanoparticles (UCNPs) as a Molecular Probing Agent Using Swept Source Optical Coherence Tomography (SSOCT)

      In Vitro Imaging of Animal Tissue with Upconversion Nanoparticles (UCNPs) as a Molecular Probing Agent Using Swept Source Optical Coherence Tomography (SSOCT)
      Purpose The aim of the current study is to demonstrate the potential of rare earth (RE) based upconversion nanoparticles (UCNPs) as molecular probing agents for non-invasive depth-resolved bioimaging technique, swept-source optical coherence tomography (SSOCT). Methods The Na + doped La 2 O 3 :Er 3+ /Yb 3+ UCNPs were synthesized using a solution combustion route with characterization for emission spectra and morphological study. A custom made SSOCT system was also incorporated ...
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    5. Towards characterization of bacterial colonies and biofilms: an approach based on swept source optical coherence tomography

      Towards characterization of bacterial colonies and biofilms: an approach based on swept source optical coherence tomography
      The continuous development of microorganism colonies may lead to the development of biofilms. The ability to observe bacterial layers in real time using Optical Coherence Tomography (OCT) can be beneficial for cross-sectional growth studies of bacterial biofilms. A new mathematical model has been developed and utilized to calculate the backscattering optical properties of sample and estimate the necessary parameters. The spectroscopic based analytical method has been successfully demonstrated for characterization ...
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      Mentions: Raju Poddar
    6. Investigation of Puccinia triticina contagion on wheat leaves using swept source optical coherence tomography

      Investigation of Puccinia triticina contagion on wheat leaves using swept source optical coherence tomography
      We present an investigation on applicability of swept-source optical coherence tomography (SSOCT) to examine the internal structures of plant leaves. This study helps to identify the growth and spread of the leaf rust disease in leaves of wheat plants, caused by Puccinia triticina . The epidermal cell layer and parenchyma cell layer of the acquired OCT images are correlated with the histological images to show distinctive leaf morphological boundaries. In the ...
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      Mentions: Raju Poddar
    7. Zinc oxide nanoparticles (ZnONPs) as contrast agent for imaging of animal tissue using swept source optical coherence tomography (SSOCT)

      Zinc oxide nanoparticles (ZnONPs) as contrast agent for imaging of animal tissue using swept source optical coherence tomography (SSOCT)
      We present applicability of ZnO nanoparticles (ZnONPs) as a potential contrast agent for Optical Coherence Tomography (OCT) imaging. A 1064nm laser source was used in a swept source configuration capable of a scanning rate of 100kHz (100,000A-lines/s). Swept Source Optical Coherence Tomography (SSOCT) is a variation of OCT, offering greater scan rates, higher resolution and signal-to-noise ratios. To enhance the contrast of an OCT frame, ZnO nanoparticles were ...
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      Mentions: Raju Poddar
    8. Imaging of human finger nail-fold with MHz A-scan rate swept source optical coherence tomography

      Imaging of human finger nail-fold with MHz A-scan rate swept source optical coherence tomography
      We present a non-invasive three-dimensional depth-resolved micro-structure and micro-vasculature imaging of a human fingernail-fold with a swept-source optical coherence tomography (ssOCT) system at a 1064nm center wavelength. A phase variance OCT angiography (OCTA) method was implemented for motion contrast OCT imaging. A Fourier-domain mode-locked light source with an A-scan rate of 1.7 MHz (1 700000 A-scans s 1 ) was utilized for imaging. The experimental setup demonstrates OCT and OCTA ...
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      Mentions: Raju Poddar
    9. TiO2 nanoparticles as exogenous contrast agent for 1 µm swept source optical coherence tomography: an in vitro study

      TiO2 nanoparticles as exogenous contrast agent for 1 µm swept source optical coherence tomography: an in vitro study
      Optical coherence tomography (OCT) is a rapidly evolving, robust technology that has profoundly changed the practice of medical imaging. Swept source OCT (SSOCT) combines the standard time domain and the spatially encoded frequency domain OCT. We have employed a high-speed SSOCT system that utilizes a swept source laser with an A-scan rate of 100kHz and a central wavelength of 1060nm for the imaging of the tissue. SSOCT at 1060nm allows ...
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      Mentions: Raju Poddar
    10. Silver nanoparticles (AgNPs) as a contrast agent for imaging of animal tissue using swept-source optical coherence tomography (SSOCT)

      Silver nanoparticles (AgNPs) as a contrast agent for imaging of animal tissue using swept-source optical coherence tomography (SSOCT)
      We present noninvasive three-dimensional depth-resolved imaging of animal tissue with a swept-source optical coherence tomography system at 1064nm center wavelength and silver nanoparticles (AgNPs) as a potential contrast agent. A swept-source laser light source is used to enable an imaging rate of 100kHz (100000 A-scans s 1 ). Swept-source optical coherence tomography is a new variant of the optical coherence tomography (OCT) technique, offering unique advantages in terms of sensitivity, reduction ...
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      Mentions: Raju Poddar
    11. Challenges and advantages in wide-field optical coherence tomography angiography imaging of the human retinal and choroidal vasculature at 1.7-MHz A-scan rate

      Challenges and advantages in wide-field optical coherence tomography angiography imaging of the human retinal and choroidal vasculature at 1.7-MHz A-scan rate
      We present noninvasive, three-dimensional, depth-resolved imaging of human retinal and choroidal blood circulation with a swept-source optical coherence tomography (OCT) system at 1065-nm center wavelength. Motion contrast OCT imaging was performed with the phase-variance OCT angiography method. A Fourier-domain mode-locked light source was used to enable an imaging rate of 1.7 MHz. We experimentally demonstrate the challenges and advantages of wide-field OCT angiography (OCTA). In the discussion, we consider ...
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    12. Imaging of the human choroid with a 1.7 MHz A-scan rate FDML swept source OCT system

      Imaging of the human choroid with a 1.7 MHz A-scan rate FDML swept source OCT system
      We demonstrate OCT angiography (OCTA) and Doppler OCT imaging of the choroid in the eyes of two healthy volunteers and in a geographic atrophy case. We show that visualization of specific choroidal layers requires selection of appropriate OCTA methods. We investigate how imaging speed, B-scan averaging and scanning density influence visualization of various choroidal vessels. We introduce spatial power spectrum analysis of OCT en face angiographic projections as a method ...
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    13. Implementation of the swept source optical coherence tomography (SSOCT) system with a statistical method to analyze optical properties of turbid media

      Implementation of the swept source optical coherence tomography (SSOCT) system with a statistical method to analyze optical properties of turbid media
      We present a spectroscopic OCT (sOCT) system to extract spectroscopic properties of turbid media using principle component analysis (PCA) and swept source optical coherence tomography (SSOCT). Extracted results are well comparable with the standard photo spectrometer technique. This system has potential for real time measurement of blood oxygen saturation and monitoring of relative concentration for other metabolic compounds inside human body.
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      Mentions: Raju Poddar
    14. In vivo volumetric depth-resolved vasculature imaging of human limbus and sclera with 1μm swept source phase-variance optical coherence angiography

      In vivo volumetric depth-resolved vasculature imaging of human limbus and sclera with 1μm swept source phase-variance optical coherence angiography
      We present in vivo volumetric depth-resolved vasculature images of the anterior segment of the human eye acquired with phase-variance based motion contrast using a high-speed (100 kHz, 10 5 A-scans/s) swept source optical coherence tomography system (SSOCT). High phase stability SSOCT imaging was achieved by using a computationally efficient phase stabilization approach. The human corneoscleral junction and sclera were imaged with swept source phase-variance optical coherence angiography and compared ...
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    15. In vivo imaging of human vasculature in the chorioretinal complex using phase-variance contrast method with phase-stabilized 1-μm swept-source optical coherence tomography

      In vivo imaging of human vasculature in the chorioretinal complex using phase-variance contrast method with phase-stabilized 1-μm swept-source optical coherence tomography
      We present a noninvasive phase-variance (pv)based motion contrast method for depth-resolved imaging of the human chorioretinal complex microcirculation with a newly developed phase-stabilized high speed (100-kHz A-scans/s) 1 - m swept-source optical coherence tomography (SSOCT) system. Compared to our previous spectral-domain (spectrometer based) pv-spectral domain OCT (SDOCT) system, this system has the advantages of higher sensitivity, reduced fringe wash-out for high blood flow speeds and deeper penetration in choroid ...
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    16. In vitro 3D anterior segment imaging in lamb eye with extended depth range swept source optical coherence tomography

      In vitro 3D anterior segment imaging in lamb eye with extended depth range swept source optical coherence tomography
      A complex conjugate resolved, extended depth range, high speed 1 m swept-source optical coherence tomography (SSOCT) provides a dense three-dimensional (3-D) imaging of the entire anterior segment of eye. SSOCT system utilizes coherence revival characteristics of the light source (external cavity tunable laser, ECTL), which is automatically phase modulated. We describe implementation of this with a common swept laser with built-in k-clock to allow imaging in high depth range, 10 ...
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  2. About Raju Poddar

    Raju Poddar

    Raju Poddar has received BS in Physics, MS in Biophysics, MTech in Biotechnology. He has a doctoral degree in technology received from Birla Institute of Technology, India. He has completed his scientific trainings from NTU, Singapore (Research Associate), Tsukuba University, Japan (post-doctoral position) and VSRI University of California, Davis, USA (visiting assistant professor and post-doctoral position). He is currently an assistant professor at the Dept. of Bio-Engineering, Birla Institute of Technology, Ranchi, India. He has published more than 35 peer-reviewed papers. His current research interests include optical coherence tomography, medical imaging, and optoelectronic systems