Articles that mention Rainer A. Leitgeb -Optical Coherence Tomography News

Rainer A. Leitgeb

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1. Mentioned In 99 Articles
2. Synthetic subaperture-based angle-independent Doppler flow measurements using single-beam line field optical coherence tomography in vivo
  
  Explore OSA | OSA Publishing Feb 13 2019
  
  We demonstrate a synthetic subaperture-based angle-independent Doppler flow calculation, using a line field spectral domain optical coherence tomography system. The high speed of the system features a high phase stability over the volume, which is necessary to apply synthetic subapertures in the aperture plane. Thus, the flow component for each subaperture can be reconstructed in postprocessing. Capillary phantom and in vivo retinal imaging experiments were performed to validate and demonstrate ...
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  Mentions: Rainer A. Leitgeb Medical University of Vienna Lara M. Wurster
3. Numerically focused full-field swept-source optical coherence microscopy with structured illumination
  
  Explore OSA | OSA Publishing Dec 19 2018
  
  This paper presents an experimental investigation of the possibility of transverse resolution improvement combined with effective numerically focused 3D imaging in full-field swept-source optical coherence microscopy (OCM) by using structured illumination and specific numerical post-processing. The possibility of transverse resolution improvement of the OCM coherence signal combined with the possibility of numerical focusing is demonstrated by imaging a resolution test target in the optical focus and defocus regions. The possibility ...
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  Mentions: Rainer A. Leitgeb Medical University of Vienna
4. Combination of High-Resolution Optical Coherence Tomography and Raman Spectroscopy for Improved Staging and Grading in Bladder Cancer
  
  Explore MDPI Open Access Journals Platform Nov 23 2018 Oncology , Urology
  
  We present a combination of optical coherence tomography (OCT) and Raman spectroscopy (RS) for improved diagnosis and discrimination of different stages and grades of bladder cancer ex vivo by linking the complementary information provided by these two techniques. Bladder samples were obtained from biopsies dissected via transurethral resection of the bladder tumor (TURBT). As OCT provides structural information rapidly, it was used as a red-flag technology to scan the bladder ...
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  Mentions: Rainer A. Leitgeb Wolfgang Drexler Medical University of Vienna
5. Multimodal Optical Medical Imaging Concepts based on Optical Coherence Tomography
  
  Explore Frontiers Oct 2 2018
  
  Optical medical imaging techniques in general exhibit outstanding resolution and molecule-specific contrast. They come however with a limited penetration in depth and small field of view. Multimodal concepts help to combine complementary strengths of different imaging technologies. The present article reviews the advantages of optical multimodal imaging concepts using optical coherence tomography (OCT) as core technology. In particular we first discuss polarization sensitive OCT, Doppler OCT and OCT angiography, OCT ...
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  Mentions: Rainer A. Leitgeb Medical University of Vienna Bernhard Baumann
6. Feature Of The Week 07/01/2018: Endoscopic Optical Coherence Tomography with a Flexible Fiber Bundle
  
  Explore Optical Coherence Tomography News Jun 30 2018
  
  We demonstrate in vivo endoscopic optical coherence tomography (OCT) imaging in the forward direction using a flexible fiber bundle (FB). In comparison to current conventional forward-looking probe schemes, our approach simplifies the endoscope design by avoiding the integration of any beam steering components in the distal probe end due to two-dimensional scanning of a focused light beam over the proximal FB surface. We describe the challenges that arise when OCT ...
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  Mentions: Rainer A. Leitgeb Medical University of Vienna Abhishek Kumar
7. Endoscopic optical coherence tomography with a flexible fiber bundle
  
  Explore SPIE Digital Library Jun 15 2018
  
  We demonstrate in vivo endoscopic optical coherence tomography (OCT) imaging in the forward direction using a flexible fiber bundle (FB). In comparison to current conventional forward-looking probe schemes, our approach simplifies the endoscope design by avoiding the integration of any beam steering components in the distal probe end due to two-dimensional scanning of a focused light beam over the proximal FB surface. We describe the challenges that arise when OCT ...
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  Mentions: Rainer A. Leitgeb Medical University of Vienna Abhishek Kumar
8. Compact akinetic swept source optical coherence tomography angiography at 1060 nm supporting a wide field of view and adaptive optics imaging modes of the posterior eye
  
  Explore OSA | OSA Publishing Apr 16 2018 Ophthalmology
  
  Imaging of the human retina with high resolution is an essential step towards improved diagnosis and treatment control. In this paper, we introduce a compact, clinically user-friendly instrument based on swept source optical coherence tomography (SS-OCT). A key feature of the system is the realization of two different operation modes. The first operation mode is similar to conventional OCT imaging and provides large field of view (FoV) images (up to ...
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  Mentions: Rainer A. Leitgeb Wolfgang Drexler Michael Pircher
9. Endoscopic optical coherence tomography with a flexible fiber bundle
  
  Explore arxiv.org Feb 27 2018 Probes
  
  We demonstrate in vivo endoscopic optical coherence tomography (OCT) imaging in the forward direction using a flexible fiber bundle. In comparison to current conventional forward looking probe schemes, our approach simplifies the endoscope design by avoiding the integration of any beam steering components in the distal probe end due to 2D scanning of a focused light beam over the proximal fiber bundle surface. We describe the challenges that arise when ...
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  Mentions: Rainer A. Leitgeb Medical University of Vienna Abhishek Kumar
10. Holographic line field en-face OCT with digital adaptive optics in the retina in vivo
  
  Explore OSA | OSA Publishing Jan 15 2018
  
  We demonstrate a high-resolution line field en-face time domain optical coherence tomography (OCT) system using an off-axis holography configuration. Line field en-face OCT produces high speed en-face images at rates of up to 100 Hz. The high frame rate favors good phase stability across the lateral field-of-view which is indispensable for digital adaptive optics (DAO). Human retinal structures are acquired in-vivo with a broadband light source at 840 nm, and ...
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  Mentions: Rainer A. Leitgeb Medical University of Vienna Tilman Schmoll
11. Non-invasive multimodal optical coherence and photoacoustic tomography for human skin imaging
  
  Explore Nature Publishing Group Dec 26 2017 Dermatology
  
  The cutaneous vasculature is involved in many diseases. Current clinical examination techniques, however, cannot resolve the human vasculature with all plexus in a non-invasive manner. By combining an optical coherence tomography system with angiography extension and an all optical photoacoustic tomography system, we can resolve in 3D the blood vessels in human skin for all plexus non-invasively. With a customized imaging unit that permits access to various parts of patients ...
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  Mentions: Rainer A. Leitgeb Wolfgang Drexler Medical University of Vienna
12. Noniterative digital aberration correction for cellular resolution retinal optical coherence tomography in vivo
  
  Explore OSA | OSA Publishing Jul 31 2017 Ophthalmology
  
  .... Visual Sci. 52, 3908–3913 (2011). [Crossref] L. Ginner, C. Blatter, D. Fechtig, T. Schmoll, M. Gröschl, and R. A. Leitgeb, “Wide-field OCT angiography at 400 KHz utilizing spectral splitting,” Photonics 1, 369–379 (201...
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  Mentions: Rainer A. Leitgeb Michael Pircher Medical University of Vienna
13. Twenty-five years of optical coherence tomography: the paradigm shift in sensitivity and speed provided by Fourier domain OCT
  
  Explore OSA | OSA Publishing Jun 20 2017
  
  Optical coherence tomography (OCT) has become one of the most successful optical technologies implemented in medicine and clinical practice mostly due to the possibility of non-invasive and non-contact imaging by detecting back-scattered light. OCT has gone through a tremendous development over the past 25 years. From its initial inception in 1991 [Science 254 , 1178 (1991)] it has become an indispensable medical imaging technology in ophthalmology. Also in fields like cardiology ...
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  Mentions: Johannes F. de Boer Rainer A. Leitgeb Maciej Wojtkowski
14. Visualization of micro-capillaries using optical coherence tomography angiography with and without adaptive optics
  
  Explore OSA | OSA Publishing Dec 17 2016 Ophthalmology
  
  The purpose of this work is to investigate the benefits of adaptive optics (AO) technology for optical coherence tomography angiography (OCTA). OCTA has shown great potential in non-invasively enhancing the contrast of vessels and small capillaries. Especially the capability of the technique to visualize capillaries with a lateral extension that is below the transverse resolution of the system opens unique opportunities in diagnosing retinal vascular diseases. However, there are some ...
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  Mentions: Rainer A. Leitgeb Wolfgang Drexler Michael Pircher
15. Comparative study between a spectral domain and a high-speed single-beam swept source OCTA system for identifying choroidal neovascularization in AMD
  
  Explore Nature Publishing Group Dec 10 2016 Ophthalmology
  
  This comparative study between a SD- and SS-OCTA system for visualizing neovascular patterns in AMD, also assessed the influence of cataract on OCTA imaging. 25 eyes with active CNV (AMD) were documented by FA, ICGA and SD-OCT. Two OCTA devices were used: A custom built SS-OCTA (1050nm, 400,000 A-scans/s, 55mm, no image segmentation); AngioVue (OptoVue, CA, USA) SD-OCTA (840nm, 70.000 A-scans/s, 33mm, SSADA technology). Two retina ...
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  Mentions: Rainer A. Leitgeb Optovue Medical University of Vienna
16. Comprehensive vascular imaging using optical coherence tomography-based angiography and photoacoustic tomography
  
  Explore SPIE | Journal Sep 23 2016
  
  Studies have proven the relationship between cutaneous vasculature abnormalities and dermatological disorders, but to image vasculature noninvasively in vivo , advanced optical imaging techniques are required. In this study, we imaged a palm of a healthy volunteer and three subjects with cutaneous abnormalities with photoacoustic tomography (PAT) and optical coherence tomography with angiography extension (OCTA). Capillaries in the papillary dermis that are too small to be discerned with PAT are visualized ...
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  Mentions: Rainer A. Leitgeb Wolfgang Drexler University College London
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