1. Rainer A. Leitgeb

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    1. Mentioned In 95 Articles

    2. Feature Of The Week 07/01/2018: Endoscopic Optical Coherence Tomography with a Flexible Fiber Bundle

      Explore Optical Coherence Tomography News
      Feature Of The Week 07/01/2018: Endoscopic Optical Coherence Tomography with a Flexible Fiber Bundle
      We demonstrate in vivo endoscopic optical coherence tomography (OCT) imaging in the forward direction using a flexible fiber bundle (FB). In comparison to current conventional forward-looking probe schemes, our approach simplifies the endoscope design by avoiding the integration of any beam steering components in the distal probe end due to two-dimensional scanning of a focused light beam over the proximal FB surface. We describe the challenges that arise when OCT ...
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      Mentions: Rainer A. Leitgeb Medical University of Vienna Abhishek Kumar

    3. Endoscopic optical coherence tomography with a flexible fiber bundle

      Explore SPIE Digital Library
      Endoscopic optical coherence tomography with a flexible fiber bundle
      We demonstrate in vivo endoscopic optical coherence tomography (OCT) imaging in the forward direction using a flexible fiber bundle (FB). In comparison to current conventional forward-looking probe schemes, our approach simplifies the endoscope design by avoiding the integration of any beam steering components in the distal probe end due to two-dimensional scanning of a focused light beam over the proximal FB surface. We describe the challenges that arise when OCT ...
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      Mentions: Rainer A. Leitgeb Medical University of Vienna Abhishek Kumar

    4. Compact akinetic swept source optical coherence tomography angiography at 1060 nm supporting a wide field of view and adaptive optics imaging modes of the posterior eye

      Explore OSA | OSA Publishing Ophthalmology
      Compact akinetic swept source optical coherence tomography angiography at 1060 nm supporting a wide field of view and adaptive optics imaging modes of the posterior eye
      Imaging of the human retina with high resolution is an essential step towards improved diagnosis and treatment control. In this paper, we introduce a compact, clinically user-friendly instrument based on swept source optical coherence tomography (SS-OCT). A key feature of the system is the realization of two different operation modes. The first operation mode is similar to conventional OCT imaging and provides large field of view (FoV) images (up to ...
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      Mentions: Rainer A. Leitgeb Wolfgang Drexler Michael Pircher

    5. Endoscopic optical coherence tomography with a flexible fiber bundle

      Explore arxiv.org Probes
      Endoscopic optical coherence tomography with a flexible fiber bundle
      We demonstrate in vivo endoscopic optical coherence tomography (OCT) imaging in the forward direction using a flexible fiber bundle. In comparison to current conventional forward looking probe schemes, our approach simplifies the endoscope design by avoiding the integration of any beam steering components in the distal probe end due to 2D scanning of a focused light beam over the proximal fiber bundle surface. We describe the challenges that arise when ...
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      Mentions: Rainer A. Leitgeb Medical University of Vienna Abhishek Kumar

    6. Holographic line field en-face OCT with digital adaptive optics in the retina in vivo

      Explore OSA | OSA Publishing
      Holographic line field en-face OCT with digital adaptive optics in the retina in vivo
      We demonstrate a high-resolution line field en-face time domain optical coherence tomography (OCT) system using an off-axis holography configuration. Line field en-face OCT produces high speed en-face images at rates of up to 100 Hz. The high frame rate favors good phase stability across the lateral field-of-view which is indispensable for digital adaptive optics (DAO). Human retinal structures are acquired in-vivo with a broadband light source at 840 nm, and ...
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      Mentions: Rainer A. Leitgeb Medical University of Vienna Tilman Schmoll

    7. Non-invasive multimodal optical coherence and photoacoustic tomography for human skin imaging

      Explore Nature Publishing Group Dermatology
      Non-invasive multimodal optical coherence and photoacoustic tomography for human skin imaging
      The cutaneous vasculature is involved in many diseases. Current clinical examination techniques, however, cannot resolve the human vasculature with all plexus in a non-invasive manner. By combining an optical coherence tomography system with angiography extension and an all optical photoacoustic tomography system, we can resolve in 3D the blood vessels in human skin for all plexus non-invasively. With a customized imaging unit that permits access to various parts of patients ...
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      Mentions: Rainer A. Leitgeb Wolfgang Drexler Medical University of Vienna

    8. Noniterative digital aberration correction for cellular resolution retinal optical coherence tomography in vivo

      Explore OSA | OSA Publishing Ophthalmology
      Noniterative digital aberration correction for cellular resolution retinal optical coherence tomography in vivo
      .... Visual Sci. 52, 3908–3913 (2011). [Crossref] L. Ginner, C. Blatter, D. Fechtig, T. Schmoll, M. Gröschl, and R. A. Leitgeb, “Wide-field OCT angiography at 400 KHz utilizing spectral splitting,” Photonics 1, 369–379 (201...
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      Mentions: Rainer A. Leitgeb Michael Pircher Medical University of Vienna

    9. Twenty-five years of optical coherence tomography: the paradigm shift in sensitivity and speed provided by Fourier domain OCT

      Explore OSA | OSA Publishing
      Twenty-five years of optical coherence tomography: the paradigm shift in sensitivity and speed provided by Fourier domain OCT
      Optical coherence tomography (OCT) has become one of the most successful optical technologies implemented in medicine and clinical practice mostly due to the possibility of non-invasive and non-contact imaging by detecting back-scattered light. OCT has gone through a tremendous development over the past 25 years. From its initial inception in 1991 [Science 254 , 1178 (1991)] it has become an indispensable medical imaging technology in ophthalmology. Also in fields like cardiology ...
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      Mentions: Johannes F. de Boer Rainer A. Leitgeb Maciej Wojtkowski

    10. Visualization of micro-capillaries using optical coherence tomography angiography with and without adaptive optics

      Explore OSA | OSA Publishing Ophthalmology
      Visualization of micro-capillaries using optical coherence tomography angiography with and without adaptive optics
      The purpose of this work is to investigate the benefits of adaptive optics (AO) technology for optical coherence tomography angiography (OCTA). OCTA has shown great potential in non-invasively enhancing the contrast of vessels and small capillaries. Especially the capability of the technique to visualize capillaries with a lateral extension that is below the transverse resolution of the system opens unique opportunities in diagnosing retinal vascular diseases. However, there are some ...
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      Mentions: Rainer A. Leitgeb Wolfgang Drexler Michael Pircher

    11. Comparative study between a spectral domain and a high-speed single-beam swept source OCTA system for identifying choroidal neovascularization in AMD

      Explore Nature Publishing Group Ophthalmology
      Comparative study between a spectral domain and a high-speed single-beam swept source OCTA system for identifying choroidal neovascularization in AMD
      This comparative study between a SD- and SS-OCTA system for visualizing neovascular patterns in AMD, also assessed the influence of cataract on OCTA imaging. 25 eyes with active CNV (AMD) were documented by FA, ICGA and SD-OCT. Two OCTA devices were used: A custom built SS-OCTA (1050nm, 400,000 A-scans/s, 55mm, no image segmentation); AngioVue (OptoVue, CA, USA) SD-OCTA (840nm, 70.000 A-scans/s, 33mm, SSADA technology). Two retina ...
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      Mentions: Rainer A. Leitgeb Optovue Medical University of Vienna

    12. Comprehensive vascular imaging using optical coherence tomography-based angiography and photoacoustic tomography

      Explore SPIE | Journal
      Comprehensive vascular imaging using optical coherence tomography-based angiography and photoacoustic tomography
      Studies have proven the relationship between cutaneous vasculature abnormalities and dermatological disorders, but to image vasculature noninvasively in vivo , advanced optical imaging techniques are required. In this study, we imaged a palm of a healthy volunteer and three subjects with cutaneous abnormalities with photoacoustic tomography (PAT) and optical coherence tomography with angiography extension (OCTA). Capillaries in the papillary dermis that are too small to be discerned with PAT are visualized ...
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      Mentions: Rainer A. Leitgeb Wolfgang Drexler University College London

    13. Combined multi-modal photoacoustic tomography, optical coherence tomography (OCT) and OCT angiography system with an articulated probe for in vivo human skin structure and vasculature imaging

      Explore OSA | OSA Publishing Dermatology
      Combined multi-modal photoacoustic tomography, optical coherence tomography (OCT) and OCT angiography system with an articulated probe for in vivo human skin structure and vasculature imaging
      Cutaneous blood flow accounts for approximately 5% of cardiac output in human and plays a key role in a number of a physiological and pathological processes. We show for the first time a multi-modal photoacoustic tomography (PAT), optical coherence tomography (OCT) and OCT angiography system with an articulated probe to extract human cutaneous vasculature in vivo in various skin regions. OCT angiography supplements the microvasculature which PAT alone is unable ...
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      Mentions: Rainer A. Leitgeb Wolfgang Drexler University College London

    15. Key Developments for Partial Coherence Biometry and Optical Coherence Tomography in the Human Eye Made in Vienna

      Explore IOVS Journal Ophthalmology
      Key Developments for Partial Coherence Biometry and Optical Coherence Tomography in the Human Eye Made in Vienna
      Purpose : To describe key developments of optical biometry and optical coherence tomography (OCT) for ophthalmic applications made by one of the pioneering research groups. Methods : Partial coherence interferometry (PCI) as the basic ranging technology for modern optical biometry and for OCT was introduced for biomedical applications in the 1980s. Later, Fourier domain (FD) OCT was introduced and demonstrated to provide superior sensitivity as compared to time domain OCT. Further developments ...
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      Mentions: Adolf F. Fercher Christoph K. Hitzenberger Rainer A. Leitgeb

    16. Systems and methods for sub-aperture based aberration measurement and correction in interferometric imaging

      Explore uspto.gov Patents
      Systems and methods for sub-aperture based aberration measurement and correction in interferometric imaging
      Systems and methods for sub-aperture correlation based wavefront measurement in a thick sample and correction as a post processing technique for interferometric imaging to achieve near diffraction limited resolution are described. Theory, simulation and experimental results are presented for the case of full field interference microscopy. The inventive technique can be applied to any coherent interferometric imaging technique and does not require knowledge of any system parameters. In one embodiment ...
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      Mentions: Rainer A. Leitgeb Carl Zeiss Meditec Alexandre R. Tumlinson
    17. 1-15 of 95 1 2 3 4 5 6 7 »
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  4. About Rainer A. Leitgeb

    Rainer A. Leitgeb

    Rainer Andreas Leitgeb is at the Center of Biomedical Engineering and Physics at the Medical University of Vienna, Vienna, Austria. Dr. Leitgeb is a physicist specializing in coherent imaging techniques and advanced microscopy. He researches modern techniques of Doppler tomography and is actively working in the functional imaging of tissue physiology.

  5. Related Topics

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    2. Comparison of three-dimensional optical coherence tomography and high resolution photography for art conservation studies
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    3. Cyclic reconstruction of 4D retinal blood flow with pulse synchronization
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    4. Processing advantages of linear chirped fiber Bragg gratings in the time domain realization of optical frequency-domain reflectometry
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    5. Ultrahigh resolution optical coherence tomography and pancorrection for cellular imaging of the living human retina
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  6. Quotes

    1. The condition of the vascular network carries important information on tissue health and its nutrition...Currently, the value of this information is not utilized to its full extent.
      In Tissues Tell the Tale: Non-Invasive Optical Technique Detects Cancer By Looking Under the Skin