1. Quing Zhu

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    1. Mentioned In 26 Articles

    2. 3D visualization of the ovarian tissue scattering coefficient with swept-source optical coherence tomography

      3D visualization of the ovarian tissue scattering coefficient with swept-source optical coherence tomography
      It is important to provide timely information to surgeons on diagnosis of a suspicious ovarian tissue before excision to avoid unnecessary surgery, especially for young women. In this report, we introduce a new 3-D surface mapping technique to map ovarian tissue scattering properties by fitting the swept-source optical coherence tomography (SS-OCT) signals to a scattering model. We observed that lower scattering coefficients and heterogeneous spatial distribution were associated with malignant ...
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      Mentions: Quing Zhu
    3. Classification of human ovarian tissue using full field optical coherence tomography

      Classification of human ovarian tissue using full field optical coherence tomography
      The feasibility of a full-field optical coherence tomography (FFOCT) system for rapid wide field optical analysis of normal and malignant human ovarian tissue pathologies was demonstrated. Five features were extracted from the normalized image histogram from 56 FFOCT images, based on the differences in the morphology of the normal and malignant tissue samples.
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    4. Classification and analysis of human ovarian tissue using full field optical coherence tomography

      Classification and analysis of human ovarian tissue using full field optical coherence tomography
      In this study, a full field optical coherence tomography (FFOCT) system was used to analyze and classify normal and malignant human ovarian tissue. 14 ovarian tissue samples (7 normal, 7 malignant) were imaged with the FFOCT system and five features were extracted by analyzing the normalized image histogram from 56 FFOCT images, based on the differences in the morphology of the normal and malignant tissue samples. A generalized linear model ...
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    5. Correlating optical coherence elastography based strain measurements with collagen content of the human ovarian tissue

      Correlating optical coherence elastography based strain measurements with collagen content of the human ovarian tissue
      In this manuscript, the initial feasibility of a catheter based phase stabilized swept source optical coherence tomography (OCT) system was studied for characterization of the strain inside different human ovarian tissue groups. The ovarian tissue samples were periodically compressed with 500 Hz square wave signal along the axial direction between the surface of an unfocused transducer and a glass cover slide. The displacement and corresponding strain were calculated during loading ...
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    6. Optical and Photoacoustic Imaging for Ovarian Cancer Detection (Thesis)

      Optical and Photoacoustic Imaging for Ovarian Cancer Detection (Thesis)
      Ovarian cancer is the fifth most common cancer among women and has the highest mortality rate of all gynecologic cancers. Current clinical imaging modalities are limited by poor sensitivity and specificity. Therefore, there is an urgent need to develop effective tools to detect ovarian cancer. In this dissertation, two imaging modalities, optical coherence tomography (OCT) and photoacoustic imaging have been investigated for ovarian cancer detection and characterization. In the first ...
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    7. Indocyanine green enhanced co-registered diffuse optical tomography and photoacoustic tomography

      Indocyanine green enhanced co-registered diffuse optical tomography and photoacoustic tomography
      To overcome the intensive light scattering in biological tissue, diffuse optical tomography (DOT) in the near-infrared range for breast lesion detection is usually combined with other imaging modalities, such as ultrasound, x-ray, and magnetic resonance imaging, to provide guidance. However, these guiding imaging modalities may depend on different contrast mechanisms compared to the optical contrast in the DOT. As a result, they cannot provide reliable guidance for DOT because some ...
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    8. A three-parameter logistic model to characterize ovarian tissue using polarization-sensitive optical coherence tomography

      A three-parameter logistic model to characterize ovarian tissue using polarization-sensitive optical coherence tomography
      Wang, Tianheng; Yang, Yi; Zhu, QuingIn this paper, a logistic prediction model is introduced to characterize the ovarian tissue. A new parameter, the phase retardation rate, was extracted from phase images of polarization-sensitive optical coherence tomography (PS-OCT). Statistical significance of this parameter between normal and ... [Biomed. Opt. Express 4, 772-777 (2013)]
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    9. Quantitative analysis of angle-resolved scattering properties of ovarian tissue using optical coherence tomography

      Quantitative analysis of angle-resolved scattering properties of ovarian tissue using optical coherence tomography
      Angle-resolved optical scattering properties of ovarian tissue, on different optical coherence tomography (OCT) imaging planes, were quantitatively measured by fitting the compounded OCT A-lines into a single scattering model. Higher cross correlation value of angle-resolved scattering coefficients between different OCT imaging planes was found in normal ovaries than was present in malignant ovaries. The mean cross correlation coefficient (MCC) was introduced in this pilot study to characterize and differentiate normal ...
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    10. Assessment of collagen changes in ovarian tissue by extracting optical scattering coefficient from OCT images

      Assessment of collagen changes in ovarian tissue by extracting optical scattering coefficient from OCT images
      Optical scattering coefficient from ex-vivo unfixed normal and malignant ovarian tissue was quantitatively extracted by fitting optical coherence tomography (OCT) A-line signals to a single scattering model. 1097 average A-line measurements at a wavelength of 1310nm were performed at 108 sites obtained from 18 ovaries. The average scattering coefficient obtained from normal group consisted of 833 measurements from 88 sites was 2.41 mm-1 (±0.59), while the average coefficient ...
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  2. About Quing Zhu

    Quing Zhu

    Quing Zhu is an Associate Professor in the Department of Electrical & Computer Engineering at the University of Connecticut.