1. Queen's University Belfast

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    1. Mentioned In 32 Articles

    2. Analyzing Anatomical Factors Contributing to Angle Closure Based on Anterior Segment Optical Coherence Tomography Imaging

      Analyzing Anatomical Factors Contributing to Angle Closure Based on Anterior Segment Optical Coherence Tomography Imaging
      Purpose To analyze anatomical factors contributing to angle closure based on anterior segment optical coherence tomography (AS-OCT) imaging. Methods A total of 238 patients with angle closure and 1122 normal controls were consecutively recruited for this study. Participants eyes were imaged using AS-OCT under the same darkened ambient light conditions. The following parameters were analyzed: central anterior chamber depth (ACD); anterior chamber area (ACA); anterior chamber volume (ACV), anterior chamber ...
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    3. OPTICAL COHERENCE TOMOGRAPHY FEATURES OF POLYPOIDAL LESION CLOSURE IN POLYPOIDAL CHOROIDAL VASCULOPATHY TREATED WITH AFLIBERCEPT

      OPTICAL COHERENCE TOMOGRAPHY FEATURES OF POLYPOIDAL LESION CLOSURE IN POLYPOIDAL CHOROIDAL VASCULOPATHY TREATED WITH AFLIBERCEPT
      Purpose: To evaluate whether optical coherence tomography (OCT) can determine polypoidal lesion (PL) perfusion in polypoidal choroidal vasculopathy (PCV) eyes following 12-months of aflibercept monotherapy. PL perfusion status, assessed by indocyanine green angiography (ICGA), is an important anatomical outcome in PCV management. Methods: Post-hoc data from a prospective randomised, open-label, study in eyes with PCV undergoing monotherapy with aflibercept evaluated PL perfusion status based on ICGA (gold standard) and OCT ...
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    4. Diabetic vascular hyperpermeability: optical coherence tomography angiography and functional loss assessments of relationships among retinal vasculature changes

      Diabetic vascular hyperpermeability: optical coherence tomography angiography and functional loss assessments of relationships among retinal vasculature changes
      Our study assessed the influence of vascular permeability on vascular flow density (FD)-correlated retinal sensitivity (RS) in DR. In this cross-sectional, prospective, consecutive study, RS in the extrafoveal macula of DR patient was measured by microperimetry. FD was measured in the total, superficial, and deep capillary plexus layers (TCP, SCP, and DCP) by optical coherence tomography angiography. All measurement points were classified into four categories according to intensity of ...
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    5. Association of ambient air pollution with age-related macular degeneration and retinal thickness in UK Biobank

      Association of ambient air pollution with age-related macular degeneration and retinal thickness in UK Biobank
      Aim To examine the associations of air pollution with both self-reported age-related macular degeneration (AMD), and in vivo measures of retinal sublayer thicknesses. Methods We included 115954 UK Biobank participants aged 4069 years old in this cross-sectional study. Ambient air pollution measures included particulate matter, nitrogen dioxide (NO 2 ) and nitrogen oxides (NO x ). Participants with self-reported ocular conditions, high refractive error ( 6 or +6 diopters) and poor spectral-domain optical ...
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    6. Objective quantification of lens nuclear opacities using swept-source anterior segment optical coherence tomography

      Objective quantification of lens nuclear opacities using swept-source anterior segment optical coherence tomography
      Background/aims: The primary objective is to quantify the lens nuclear opacity using swept-source anterior segment optical coherence tomography (SS-ASOCT) and to evaluate its correlations with Lens Opacities Classification System III (LOCS-III) system and surgical parameters. The secondary objective is to assess the diagnostic performance for hard nuclear cataract. Methods: This cross-sectional study included 1222 patients eligible for cataract surgery (1222 eyes). The latest SS-ASOCT (CASIA-2) was used to obtain ...
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    7. Optical coherence tomography angiography measured area of retinal neovascularization is predictive of treatment response and progression of disease in patients with proliferative diabetic retinopathy

      Optical coherence tomography angiography measured area of retinal neovascularization is predictive of treatment response and progression of disease in patients with proliferative diabetic retinopathy
      Background The purpose of this study was to evaluate the area of retinal neovascularization in patients with treatment-nave proliferative diabetic retinopathy (PDR) as measured by optical coherence tomography angiography (OCT-A) as a marker of subsequent treatment response after panretinal photocoagulation (PRP), and to examine if this area correlated with area of retinal neovascularization as measured by fluorescein angiography (FA). Methods En face OCT-A scans (4.5 4.5 mm) of ...
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    8. The long-term effects of anti-vascular endothelial growth factor therapy on the optical coherence tomography angiographic appearance of neovascularization in age-related macular degeneration

      The long-term effects of anti-vascular endothelial growth factor therapy on the optical coherence tomography angiographic appearance of neovascularization in age-related macular degeneration
      Background The short-term effects of anti-vascular endothelial growth factor (anti-VEGF) treatment on macular neovascularization (MNV) morphology is well described, but long-term studies on morphologic changes and correlation of such changes to the type of MNV have not been conducted. This study aims to determine if different types of MNVs in neovascular AMD (nAMD) behave differently with anti-VEGF treatment as visualized on optical coherence tomography angiography (OCTA). Methods Treatment-nave nAMD patients ...
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    9. Assessment of the Vitreomacular Interface Using High Resolution Optical Coherence Tomography in a Population Based Cohort Study of Older Adults

      Assessment of the Vitreomacular Interface Using High Resolution Optical Coherence Tomography in a Population Based Cohort Study of Older Adults
      Objective To describe the prevalence of vitreomacular interface (VMI) features classified using spectral-domain optical coherence tomography (SD-OCT) and their associated risk factors in the Northern Ireland Cohort for the Longitudinal Study of Ageing (NICOLA Study). Design Cross-sectional population-based study Participants Non-institutionalised Northern Irish adults aged 40 years. Methods Using geographic stratification, a representative sample of people in Northern Ireland was invited to participate in the NICOLA Study. SD-OCT images of ...
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    10. Diagnostic accuracy of spectral domain optical coherence tomography circumpapillary, optic nerve head and macular parameters in the detection of perimetric glaucoma

      Diagnostic accuracy of spectral domain optical coherence tomography circumpapillary, optic nerve head and macular parameters in the detection of perimetric glaucoma
      Objective To evaluate the diagnostic accuracy of circumpapillary retinal nerve fibre layer (cRNFL), optic nerve head and macular parameters for the detection of glaucoma using Heidelberg Spectralis optical coherence tomography (OCT). Design Cross-sectional study. Participants Participants of the Northern Ireland Cohort for the Longitudinal Study of Ageing (NICOLA) with a vertical cup to disc ratio (VCDR) 0.7 and/or VCDR asymmetry 0.2 and/or vertical neuroretinal rim ratio ...
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    11. Fundus autofluorescence and spectral domain optical coherence tomography as predictors for long-term functional outcome in rhegmatogenous retinal detachment

      Fundus autofluorescence and spectral domain optical coherence tomography as predictors for long-term functional outcome in rhegmatogenous retinal detachment
      Purpose To detect pre- and postoperative retinal changes in fundus autofluorescence (AF) and spectral domain optical coherence tomography (SD-OCT) and to correlate these with functional outcome in patients with primary rhegmatogenous retinal detachment (RRD). Methods A prospective, 30-month study of patients operated with 25-gauge vitrectomy for primary RRD. Patients were examined preoperatively and after 6 and 30 months, using ultrawide-field AF images (UWFI) (Optos 200Tx) and SD-OCT (Topcon 3D OCT-2000 ...
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    12. Confocal infrared imaging with optical coherence tomography provides superior detection of a number of common macular lesions compared to colour fundus photography

      Confocal infrared imaging with optical coherence tomography provides superior detection of a number of common macular lesions compared to colour fundus photography
      Purpose To compare diagnostic accuracy of confocal infrared reflectance (IR), with and without optical coherence tomography (OCT), to colour fundus photography (CFP) in the Northern Ireland Cohort for the Longitudinal Study of Ageing (NICOLA) Study. Methods Cross‐sectional observational study of participants in NICOLA. CFP, IR and IR/OCT of 640 eyes were graded for hard, soft and reticular pseudodrusen; geographic atrophy; choroidal neovascularisation; naevus; epiretinal membrane; and haemorrhages. Test ...
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    13. The diagnostic accuracy of OCT angiography in naive and treated neovascular age-related macular degeneration: a review

      The diagnostic accuracy of OCT angiography in naive and treated neovascular age-related macular degeneration: a review
      Optical coherence tomography angiography (OCTA) is a non-invasive retinal imaging innovation that has been gaining popularity for the evaluation of the retinal vasculature. Of clinical importance is its current use either as an alternative or in conjunction with conventional dye-based angiography in neovascular age-related macular degeneration. OCTA is not without limitations and these include image artefact, a relatively small field of view and failure of the segmentation algorithms, which can ...
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    14. Tomographic Biomarkers Predicting Progression to Fibrosis in Treated Neovascular Age-Related Macular Degeneration: A Multimodal Imaging Study

      Tomographic Biomarkers Predicting Progression to Fibrosis in Treated Neovascular Age-Related Macular Degeneration: A Multimodal Imaging Study
      Purpose To describe the photoreceptorretinal pigment epithelium (RPE) interface changes and to analyze the relationships between these features and hyperreflective material (HRM) with scarring and atrophy at the macula of patients with neovascular age-related macular degeneration (nAMD). Design Retrospective single-center observational study. Participants A total of 150 eyes from 144 patients with naive nAMD were included. Methods All patients had OCT (HRA-OCT Spectralis, Heidelberg Engineering, Heidelberg, Germany) at baseline and ...
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    15. Diagnostic accuracy of optical coherence tomography for diagnosing glaucoma: secondary analyses of the GATE study

      Diagnostic accuracy of optical coherence tomography for diagnosing glaucoma: secondary analyses of the GATE study
      Background/Aims To assess the diagnostic performance of retinal nerve fibre layer (RNFL) data of optical coherence tomography (OCT) for detecting glaucoma. Methods Secondary analyses of a prospective, multicentre diagnostic study (Glaucoma Automated Tests Evaluation (GATE)) referred to hospital eye services in the UK were conducted. We included data from 899 of 966 participants referred to hospital eye services with suspected glaucoma or ocular hypertension. We used both eyes data ...
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    16. Changes in Neovascular Lesion Hyperreflectivity After Anti-VEGF Treatment in Age-Related Macular Degeneration: An Integrated Multimodal Imaging Analysis

      Changes in Neovascular Lesion Hyperreflectivity After Anti-VEGF Treatment in Age-Related Macular Degeneration: An Integrated Multimodal Imaging Analysis
      Purpose : To correlate presence of hyperreflective material (HRM) on spectral-domain optical coherence tomography (SD-OCT) with color fundus photography (CFP) in patients with different subtypes of neovascular age-related macular degeneration (n-AMD). Methods : Retrospective assessments were made at baseline and months 1, 3, and 12 after initiation of treatment. At baseline, CFP images were graded for the presence of blood, fibrin and lipid exudates, and retinal angiograms for n-AMD subtype. At the ...
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    17. 1-15 of 32 1 2 »
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  2. About Queen's University Belfast

    Queen's University Belfast

    Queen's University Belfast has a record of academic achievement which stretches back more than 150 years. Founded by Queen Victoria, the Queen's University in Ireland, was designed to be a non-denominational alternative to Trinity College Dublin which was controlled by the Anglican Church. The University was made up of three Queen's Colleges - in Cork, Galway and Belfast. Although it was the first University in the north of Ireland, Queen's drew on a tradition of learning which goes back to 1810 and the foundation of the Belfast Academical Institution. Its collegiate department, which provided University-style education, closed with the establishment of Queen's and four of its professors and many of its students transferred to the new college. Founded in 1845, Queen's opened in 1849 when the first students entered the magnificent new college building designed and built by Charles Lanyon. Since then, the University estate has grown to more than 300 buildings - many of them listed for their architectural importance. The first batch of students numbered 90. Today there are some 24,000.