1. Queen's University Belfast

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    1. Mentioned In 24 Articles

    2. Diagnostic accuracy of spectral domain optical coherence tomography circumpapillary, optic nerve head and macular parameters in the detection of perimetric glaucoma

      Diagnostic accuracy of spectral domain optical coherence tomography circumpapillary, optic nerve head and macular parameters in the detection of perimetric glaucoma
      Objective To evaluate the diagnostic accuracy of circumpapillary retinal nerve fibre layer (cRNFL), optic nerve head and macular parameters for the detection of glaucoma using Heidelberg Spectralis optical coherence tomography (OCT). Design Cross-sectional study. Participants Participants of the Northern Ireland Cohort for the Longitudinal Study of Ageing (NICOLA) with a vertical cup to disc ratio (VCDR) 0.7 and/or VCDR asymmetry 0.2 and/or vertical neuroretinal rim ratio ...
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    3. Fundus autofluorescence and spectral domain optical coherence tomography as predictors for long-term functional outcome in rhegmatogenous retinal detachment

      Fundus autofluorescence and spectral domain optical coherence tomography as predictors for long-term functional outcome in rhegmatogenous retinal detachment
      Purpose To detect pre- and postoperative retinal changes in fundus autofluorescence (AF) and spectral domain optical coherence tomography (SD-OCT) and to correlate these with functional outcome in patients with primary rhegmatogenous retinal detachment (RRD). Methods A prospective, 30-month study of patients operated with 25-gauge vitrectomy for primary RRD. Patients were examined preoperatively and after 6 and 30 months, using ultrawide-field AF images (UWFI) (Optos 200Tx) and SD-OCT (Topcon 3D OCT-2000 ...
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    4. Confocal infrared imaging with optical coherence tomography provides superior detection of a number of common macular lesions compared to colour fundus photography

      Confocal infrared imaging with optical coherence tomography provides superior detection of a number of common macular lesions compared to colour fundus photography
      Purpose To compare diagnostic accuracy of confocal infrared reflectance (IR), with and without optical coherence tomography (OCT), to colour fundus photography (CFP) in the Northern Ireland Cohort for the Longitudinal Study of Ageing (NICOLA) Study. Methods Cross‐sectional observational study of participants in NICOLA. CFP, IR and IR/OCT of 640 eyes were graded for hard, soft and reticular pseudodrusen; geographic atrophy; choroidal neovascularisation; naevus; epiretinal membrane; and haemorrhages. Test ...
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    5. The diagnostic accuracy of OCT angiography in naive and treated neovascular age-related macular degeneration: a review

      The diagnostic accuracy of OCT angiography in naive and treated neovascular age-related macular degeneration: a review
      Optical coherence tomography angiography (OCTA) is a non-invasive retinal imaging innovation that has been gaining popularity for the evaluation of the retinal vasculature. Of clinical importance is its current use either as an alternative or in conjunction with conventional dye-based angiography in neovascular age-related macular degeneration. OCTA is not without limitations and these include image artefact, a relatively small field of view and failure of the segmentation algorithms, which can ...
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    6. Tomographic Biomarkers Predicting Progression to Fibrosis in Treated Neovascular Age-Related Macular Degeneration: A Multimodal Imaging Study

      Tomographic Biomarkers Predicting Progression to Fibrosis in Treated Neovascular Age-Related Macular Degeneration: A Multimodal Imaging Study
      Purpose To describe the photoreceptorretinal pigment epithelium (RPE) interface changes and to analyze the relationships between these features and hyperreflective material (HRM) with scarring and atrophy at the macula of patients with neovascular age-related macular degeneration (nAMD). Design Retrospective single-center observational study. Participants A total of 150 eyes from 144 patients with naive nAMD were included. Methods All patients had OCT (HRA-OCT Spectralis, Heidelberg Engineering, Heidelberg, Germany) at baseline and ...
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    7. Diagnostic accuracy of optical coherence tomography for diagnosing glaucoma: secondary analyses of the GATE study

      Diagnostic accuracy of optical coherence tomography for diagnosing glaucoma: secondary analyses of the GATE study
      Background/Aims To assess the diagnostic performance of retinal nerve fibre layer (RNFL) data of optical coherence tomography (OCT) for detecting glaucoma. Methods Secondary analyses of a prospective, multicentre diagnostic study (Glaucoma Automated Tests Evaluation (GATE)) referred to hospital eye services in the UK were conducted. We included data from 899 of 966 participants referred to hospital eye services with suspected glaucoma or ocular hypertension. We used both eyes data ...
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    8. Changes in Neovascular Lesion Hyperreflectivity After Anti-VEGF Treatment in Age-Related Macular Degeneration: An Integrated Multimodal Imaging Analysis

      Changes in Neovascular Lesion Hyperreflectivity After Anti-VEGF Treatment in Age-Related Macular Degeneration: An Integrated Multimodal Imaging Analysis
      Purpose : To correlate presence of hyperreflective material (HRM) on spectral-domain optical coherence tomography (SD-OCT) with color fundus photography (CFP) in patients with different subtypes of neovascular age-related macular degeneration (n-AMD). Methods : Retrospective assessments were made at baseline and months 1, 3, and 12 after initiation of treatment. At baseline, CFP images were graded for the presence of blood, fibrin and lipid exudates, and retinal angiograms for n-AMD subtype. At the ...
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    9. Optical coherence tomography angiography in paracentral acute middle maculopathy secondary to central retinal vein occlusion

      Optical coherence tomography angiography in paracentral acute middle maculopathy secondary to central retinal vein occlusion
      Purpose To report the clinical course and the optical coherence tomography angiography (OCTA) findings of patients presenting with paracentral acute middle maculopathy (PAMM) and central retinal vein occlusion (CRVO). Methods Retrospective case series. Clincal records and multimodal imaging findings of patients presenting with PAMM and CRVO were reviewed. Results Three eyes of three patients (2 males; mean age: 66 years) were included in the study. Mean follow-up was 9 months ...
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    10. Automated imaging technologies for the diagnosis of glaucoma: a comparative diagnostic study for the evaluation of the diagnostic accuracy, performance as triage tests and cost-effectiveness (GATE study

      Automated imaging technologies for the diagnosis of glaucoma: a comparative diagnostic study for the evaluation of the diagnostic accuracy, performance as triage tests and cost-effectiveness (GATE study
      Background Many glaucoma referrals from the community to hospital eye services are unnecessary. Imaging technologies can potentially be useful to triage this population. Objectives To assess the diagnostic performance and cost-effectiveness of imaging technologies as triage tests for identifying people with glaucoma. Design Within-patient comparative diagnostic accuracy study. Markov economic model comparing the cost-effectiveness of a triage test with usual care. Setting Secondary care. Participants Adults referred from the community ...
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    11. Optical coherence tomography for the diagnosis, monitoring and guiding of treatment for neovascular age-related macular degeneration: a systematic review and economic evaluation

      Optical coherence tomography for the diagnosis, monitoring and guiding of treatment for neovascular age-related macular degeneration: a systematic review and economic evaluation
      Background Age-related macular degeneration is the most common cause of sight impairment in the UK. In neovascular age-related macular degeneration (nAMD), vision worsens rapidly (over weeks) due to abnormal blood vessels developing that leak fluid and blood at the macula. Objectives To determine the optimal role of optical coherence tomography (OCT) in diagnosing people newly presenting with suspected nAMD and monitoring those previously diagnosed with the disease. Data sources Databases ...
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    12. Optical coherence tomography for the diagnosis of neovascular age-related macular degeneration: a systematic review

      Optical coherence tomography for the diagnosis of neovascular age-related macular degeneration: a systematic review
      The purpose is to study the diagnostic performance of optical coherence tomography (OCT) and alternative diagnostic tests for neovascular age-related macular degeneration (nAMD). Methods employed are as follows:systematic review and meta-analysis; Index test: OCT including time-domain (TD-OCT) and the most recently developed spectral domain (SD-OCT); comparator tests: visual acuity, clinical evaluation (slit lamp), Amsler chart, colour fundus photographs, infra-red reflectance, red-free images / blue reflectance, fundus autofluorescence imaging (FAF), indocyanine ...
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    13. A proposed model membrane and test method for microneedle insertion studies

      A proposed model membrane and test method for microneedle insertion studies
      A commercial polymeric film (Parafilm M , a blend of a hydrocarbon wax and a polyolefin) was evaluated as a model membrane for microneedle (MN) insertion studies. Polymeric MN arrays were inserted into Parafilm M (PF) and also into excised neonatal porcine skin. Parafilm M was folded before the insertions to closely approximate thickness of the excised skin. Insertion depths were evaluated using optical coherence tomography (OCT) using either a force ...
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    14. Proposed Lexicon for Anatomic Landmarks in Normal Posterior Segment Spectral-Domain Optical Coherence Tomography: The IN•OCT Consensus

      Proposed Lexicon for Anatomic Landmarks in Normal Posterior Segment Spectral-Domain Optical Coherence Tomography: The IN•OCT Consensus
      Purpose To develop a consensus nomenclature for the classification of retinal and choroidal layers and bands visible on spectral-domain optical coherence tomography (SD-OCT) images of a normal eye. Design An international panel with expertise in retinal imaging (International Nomenclature for Optical Coherence Tomography [INOCT] Panel) was assembled to define a consensus for OCT imaging terminology. Participants A panel of retina specialists. Methods A set of 3 B-scan images from a ...
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  2. About Queen's University Belfast

    Queen's University Belfast

    Queen's University Belfast has a record of academic achievement which stretches back more than 150 years. Founded by Queen Victoria, the Queen's University in Ireland, was designed to be a non-denominational alternative to Trinity College Dublin which was controlled by the Anglican Church. The University was made up of three Queen's Colleges - in Cork, Galway and Belfast. Although it was the first University in the north of Ireland, Queen's drew on a tradition of learning which goes back to 1810 and the foundation of the Belfast Academical Institution. Its collegiate department, which provided University-style education, closed with the establishment of Queen's and four of its professors and many of its students transferred to the new college. Founded in 1845, Queen's opened in 1849 when the first students entered the magnificent new college building designed and built by Charles Lanyon. Since then, the University estate has grown to more than 300 buildings - many of them listed for their architectural importance. The first batch of students numbered 90. Today there are some 24,000.