1. Qiang Wang

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    1-16 of 16
    1. Mentioned In 16 Articles

    2. Short-time series optical coherence tomography angiography and its application to cutaneous microvasculature

      Short-time series optical coherence tomography angiography and its application to cutaneous microvasculature
      We present a new optical coherence tomography (OCT) angiography method for imaging tissue microvasculature in vivo based on the characteristic frequency-domain flow signature in a short time series of a single voxel. The angiography signal is generated by Fourier transforming the OCT signal time series from a given voxel in multiple acquisitions and computing the average magnitude of non-zero (high-pass) frequency components. Larger temporal variations of the OCT signal caused ...
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    3. Label‐free volumetric imaging of conjunctival collecting lymphatics ex vivo by optical coherence tomography lymphangiography

      Label‐free volumetric imaging of conjunctival collecting lymphatics ex vivo by optical coherence tomography lymphangiography
      We employ optical coherence tomography (OCT) and optical coherence microscopy (OCM) to study conjunctival lymphatics in porcine eyes ex vivo . This study is a precursor to the development of in vivo imaging of the collecting lymphatics for potentially guiding and monitoring glaucoma filtration surgery. OCT scans at 1300 nm and higher‐resolution OCM scans at 785 nm reveal the lymphatic vessels via their optical transparency. Equivalent signal characteristics are also ...
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    4. Adaptive optics optical coherence tomography for measuring phase and reflectance dynamics of photoreceptors

      Adaptive optics optical coherence tomography for measuring phase and reflectance dynamics of photoreceptors
      Optical coherence tomography with adaptive optics (AO-OCT) is a noninvasive method for imaging the living retina at the microscopic level. We used AO-OCT technology to follow changes in cone photoreceptor outer segment (OS) length and reflectance. To substantially increase sensitivity of the length measurements, a novel phase retrieval technique was demonstrated, capable of detecting changes on a nanometer scale. We acquired volume videos of 0.65°x0.65° retinal patches ...
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    5. Adaptive optics and the eye (super resolution OCT)

      Adaptive optics and the eye (super resolution OCT)
      The combination of adaptive optics (AO) and optical coherence tomography (OCT) was first reported 8 years ago and has undergone tremendous technological advances since then. The technical benefits of adding AO to OCT (increased lateral resolution, smaller speckle, and enhanced sensitivity) increase the imaging capability of OCT in ways that make it well suited for three-dimensional (3D) cellular imaging in the retina. Today, AO–OCT systems provide ultrahigh 3D resolution ...
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    6. Three-dimensional optical coherence tomography imaging of retinal sheet implants in live rats

      Three-dimensional optical coherence tomography imaging of retinal sheet implants in live rats
      Purpose To obtain three-dimensional images from retinal transplants in live animals and evaluate the placement and structural quality of the transplants. Methods Donor retinal sheets were isolated from E19 fetuses of transgenic rats expressing human alkaline phosphatase (hPAP), and transplanted to the subretinal space of 19–56 days old S334ter-3 rat recipients with fast retinal degeneration (average age at surgery 32 days). A total of 143 rats were imaged 1 ...
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    7. Imaging retinal nerve fiber bundles at ultrahigh-speed and ultrahigh-resolution using OCT with adaptive optics

      Imaging retinal nerve fiber bundles at ultrahigh-speed and ultrahigh-resolution using OCT with adaptive optics
      Ultrahigh speed line scan detectors based on CMOS technology have been recently demonstrated in ultrahigh resolution spectral-domain optical coherence tomography (UHR-SD-OCT) for retinal imaging. While successful, fundamental tradeoffs exist been image acquisition time, image sampling density, and sensitivity, all of which impact the extent of motion artifacts, visualization of fine spatial detail, and detection of faint reflections. Here we investigate these tradeoffs for imaging retinal nerve fiber bundles (RNFBs) using ...
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    8. High-speed and wide bandwidth Fourier domain mode-locked wavelength swept laser with multiple SOAs.

      Related Articles High-speed and wide bandwidth Fourier domain mode-locked wavelength swept laser with multiple SOAs. Opt Express. 2008 Feb 18;16(4):2547-54 Authors: Jeon MY, Zhang J, Wang Q, Chen Z We report on the development of a high-speed, wide bandwidth Fourier domain mode-locked (FDML) wavelength swept laser of around 1300 nm using two gain media for high-resolution and high-speed Fourier domain optical coherence tomography. The wavelength swept laser ...
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    9. Thermoelastic optical Doppler tomography of biological tissues

      Thermoelastic optical Doppler tomography of biological tissues
      In this presentation, we demonstrate a novel optical tomography technique, thermoelastic optical Doppler tomography (ODT). Short laser pulses are used to generate thermoelastic waves in biological samples. Optical phase variations in response to wave propagation are detected using ODT. It is shown that areas of different elastic property in the phantom can be clearly resolved.
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    10. 1-16 of 16
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  2. About Qiang Wang

    Qiang Wang

    Qiang Wang is with the School of Optometry at Indiana University.