1. Pusan National University

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    1. Mentioned In 57 Articles

    2. Preclinical mouse model of optical coherence tomography for subcortical brain imaging without dissection

      Preclinical mouse model of optical coherence tomography for subcortical brain imaging without dissection
      Background The purpose of this study was to investigate the feasibility of using optical coherence tomography (OCT) to identify internal brain lesions, specifically intracerebral hemorrhage, without dissection. Methods Mice with artificially injected brain hematomas were used to test the OCT system, and the recorded images were compared with microscopic images of the same mouse brains after hematoxylin and eosin staining. Results The intracranial structures surrounding the hematomas were clearly visualized ...
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    3. Full-field optical coherence tomography using tunable-path-difference source for three-dimensional multi-layered imaging with enhanced signal-to-noise ratio

      Full-field optical coherence tomography using tunable-path-difference source for three-dimensional multi-layered imaging with enhanced signal-to-noise ratio
      We demonstrate a novel scheme for a full-field optical coherence tomography (FF-OCT) system using a tunable-path-difference source (TPDS). Recently, the comb-spacing-swept source (CSWS) method, including TPDS, has been successfully applied to improve the stability of three-dimensional (3D) time-domain (TD)-FF-OCT imaging by eliminating the mechanical scanning of the reference path, which has been the main source of undesirable noise in general TD-OCT. However, CSWS-OCT has the drawback of a degraded ...
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    4. Visual Field Inference From Optical Coherence Tomography Using Deep Learning Algorithms: A Comparison Between Devices

      Visual Field Inference From Optical Coherence Tomography Using Deep Learning Algorithms: A Comparison Between Devices
      Purpose: To develop a deep learning model to estimate the visual field (VF) from spectral-domain optical coherence tomography (SD-OCT) and swept-source OCT (SS-OCT) and to compare the performance between them. Methods: Two deep learning models based on Inception-ResNet-v2 were trained to estimate 24-2 VF from SS-OCT and SD-OCT images. The estimation performance of the two models was evaluated by using the root mean square error between the actual and estimated ...
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    5. Mammalian Cochlear Hair Cell Imaging Using Optical Coherence Tomography (OCT): A Preliminary Study

      Mammalian Cochlear Hair Cell Imaging Using Optical Coherence Tomography (OCT): A Preliminary Study
      Objectives: This study aimed to investigate the feasibility of using optical coherence tomography (OCT) to provide information about cochlear microanatomy at a cellular level, specifically of cochlear hair cells in mammals. Materials and methods: A total of 10 Sprague-Dawley rats were divided into 2 experimental groups for comparing the arrangement of normal and damaged hair cells. Postnatal day 3 Sprague-Dawley rats were used to test the swept-source OCT system, and ...
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    6. Linear-in-wavenumber actively-mode-locked wavelength-swept laser

      Linear-in-wavenumber actively-mode-locked wavelength-swept laser
      We report on an akinetic actively-mode-locked wavelength-swept laser (ASL) with a sweep that is highly linear in wavenumber. By tailoring the drive waveform of the intracavity modulator, the wavenumber sweep was further linearized to enable high fidelity frequency-domain interferometric ranging without resampling of the acquired data. Used for catheter-based optical coherence tomography, the ASL showed comparable imaging performance to a state-of-the-art polygon-based wavelength-swept source at a matching sweep rate of ...
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    7. Comparison of optical coherence tomography–guided versus intravascular ultrasound–guided percutaneous coronary intervention: Rationale and design of a randomized, controlled OCTIVUS trial

      Comparison of optical coherence tomography–guided versus intravascular ultrasound–guided percutaneous coronary intervention: Rationale and design of a randomized, controlled OCTIVUS trial
      Background The clinical value of intracoronary imaging for percutaneous coronary intervention (PCI) guidance is well acknowledged. Intravascular ultrasound (IVUS) and optical coherence tomography (OCT) are the most commonly used intravascular imaging to guide and optimize PCI in day-to-day practice. However, the comparative effectiveness of IVUS-guided versus OCT-guided PCI with respect to clinical end points remains unknown. Methods and design The OCTIVUS study is a prospective, multicenter, open-label, parallel-arm, randomized trial ...
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    8. Prediction of visual field from swept-source optical coherence tomography using deep learning algorithms

      Prediction of visual field from swept-source optical coherence tomography using deep learning algorithms
      Purpose To develop a deep learning method to predict visual field (VF) from wide-angle swept-source optical coherence tomography (SS-OCT) and compare the performance of three Google Inception architectures. Methods Three deep learning models (with Inception-ResNet-v2, Inception-v3, and Inception-v4) were trained to predict 24-2 VF from the macular ganglion cell-inner plexiform layer and the peripapillary retinal nerve fibre layer map obtained by SS-OCT. The prediction performance of the three models was ...
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    9. Impact of Scan Tilt on Quantitative Assessments Using Optical Coherence Tomography Angiography

      Impact of Scan Tilt on Quantitative Assessments Using Optical Coherence Tomography Angiography
      Purpose : To investigate the impact of scan tilt on quantitative assessments using swept-source optical coherence tomography angiography (SS-OCTA) in healthy participants. Methods : Healthy participants were imaged with a SS-OCTA system (PLEX Elite 9000; Carl Zeiss Meditec, Inc, Dublin, CA). After a standard scan was obtained, tilted scans were obtained by moving the optical coherence tomography beam entrance position horizontally. The tilting angle was measured from the B-scan image, and the ...
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    10. Comparison of optical coherence tomography-guided versus intravascular ultrasound-guided percutaneous coronary intervention: Rationale and Design of a Randomized, controlled OCTIVUS trial

      Comparison of optical coherence tomography-guided versus intravascular ultrasound-guided percutaneous coronary intervention: Rationale and Design of a Randomized, controlled OCTIVUS trial
      The clinical value of intracoronary imaging for percutaneous coronary intervention (PCI) guidance is well acknowledged. Intravascular ultrasound (IVUS) and optical coherence tomography (OCT) are the most common use for intravascular imaging to guide and optimize PCI in day-to-day practice. However, the comparative effectiveness of IVUS-guided and OCT-guided PCI with respect to clinical end points remains unknown. Methods and Design The OCTIVUS study is a prospective, multicenter, open-label, parallel-arm, randomized trial ...
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    11. SD-OCT parameters and visual field defect in chiasmal compression and the diagnostic value of neural network model

      SD-OCT parameters and visual field defect in chiasmal compression and the diagnostic value of neural network model
      Purpose: To evaluate the peripapillary retinal nerve fiber layer (RNFL) and macular ganglion cell-inner plexiform layer (GCIPL) measurements using spectral domain optical coherence tomography (SD-OCT) in patients with chiasmal compression and analyze the diagnostic value of a neural network model. Methods: Forty-seven patients with chiasmal compressive disorder were recruited and divided into two groups depending on the visual field defect (perimetric; group 1 and preperimetric; group 2). Fifty-seven normal subjects ...
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    12. A deep learning approach to predict visual field using optical coherence tomography

      A deep learning approach to predict visual field using optical coherence tomography
      We developed a deep learning architecture based on Inception V3 to predict visual field using optical coherence tomography (OCT) imaging and evaluated its performance. Two OCT images, macular ganglion cell-inner plexiform layer (mGCIPL) and peripapillary retinal nerve fibre layer (pRNFL) thicknesses, were acquired and combined. A convolutional neural network architecture was constructed to predict visual field using this combined OCT image. The root mean square error (RMSE) between the actual ...
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    13. Perioperative intraretinal fluid observed using optical coherence tomography in the epiretinal membrane

      Perioperative intraretinal fluid observed using optical coherence tomography in the epiretinal membrane
      Background Postoperative intraretinal fluid (IRF) is reportedly associated with visual outcomes after epiretinal membrane (ERM) surgery. However, preoperative IRF is common, and persistent IRF would have different impact on visual function from postoperative newly developed IRF. Therefore, we aimed to investigate the incidence rate and clinical implications of perioperative IRF in ERM. Methods Medical records of patients who underwent vitrectomy for idiopathic ERM between January 2014 and January 2017 were ...
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    14. Extratympanic Observation of Middle and Inner Ear Structures in Rodents Using Optical Coherence Tomography

      Extratympanic Observation of Middle and Inner Ear Structures in Rodents Using Optical Coherence Tomography
      Objectives. This study aimed to investigate whether optical coherence tomography (OCT) provides useful information about the microstructures of the middle and inner ear via extratympanic approach and thereby could be utilized as an alternative diagnostic technology in ear imaging. Method. Five rats and mice were included, and the swept-source OCT system was applied to confirm the extent of visibility of the middle and inner ear and measure the length or ...
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    15. The Shortest Radius of Curvature of Bruch's Membrane in Macular Optical Coherence Tomography

      The Shortest Radius of Curvature of Bruch's Membrane in Macular Optical Coherence Tomography
      Purpose To develop software to measure the shortest radius in curvature of Bruch's membrane from optical coherence tomography (OCT), and then to apply it to various types of eyes. Methods Macular OCT images consisting of 12 images of 9 mm radial scans were studied. The horizontal to vertical pixel ratios were changed to 1:1, and Bruch's membrane was marked automatically on each image. Software to measure the ...
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    16. Diagnostic Ability of Macular Vessel Density in the Ganglion Cell–Inner Plexiform Layer on Optical Coherence Tomographic Angiography for Glaucoma

      Diagnostic Ability of Macular Vessel Density in the Ganglion Cell–Inner Plexiform Layer on Optical Coherence Tomographic Angiography for Glaucoma
      Purpose : The purpose of this study was to analyze the macular vessel density layer-by-layer and compare the diagnostic value of each in diagnosing glaucoma. Methods : This was a prospective comparative cross-sectional study, and the setting was glaucoma referral practice. The study participants were patients with primary open-angle glaucoma undergoing treatment with drugs, and age-matched normal controls who visited our clinic for regular eye examinations for refractive errors. All participants were ...
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  2. About Pusan National University

    Pusan National University

    Pusan National University (also called Busan National University) is one of ten flagship Korean national universities and a leading university in South Korea. Continually ranked among one of top 500 world universities by ARWU World University Ranking and QS Top Universities Ranking, Pusan National University is one of only ten Korean universities ranked in both ARWU World University Ranking and QS Top Universities Ranking in 2010. In QS Top Universities Ranking 2010, Pusan National University is ranked in top five in social sciences and management, sixth in engineering and technology,[4] sixth in life science and medicine, and ninth in arts and humanities among Korean universities. Pusan National University is one of only five Korean universities ranked in four subject areas in QS Top .