1. Purdue University

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    1. Mentioned In 30 Articles

    2. Method and apparatus for motility contrast imaging

      Method and apparatus for motility contrast imaging
      A system for motility contrast imaging a biological target within tissue comprising a CCD array; an illumination source for generating an incoming beam; a first beam splitter for receiving the incoming beam and producing an object beam and a reference beam; a second beam splitter for illuminating a multitude of biological targets with the object beam and for directing backscattered object beams towards the CCD array; a computer-controlled delay stage ...
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    3. Imaging and quantifying ganglion cells and other transparent neurons in the living human retina [Engineering]

      Imaging and quantifying ganglion cells and other transparent neurons in the living human retina [Engineering]
      Ganglion cells (GCs) are fundamental to retinal neural circuitry, processing photoreceptor signals for transmission to the brain via their axons. However, much remains unknown about their role in vision and their vulnerability to disease leading to blindness. A major bottleneck has been our inability to observe GCs and their degeneration in the living human eye. Despite two decades of development of optical technologies to image cells in the living human ...
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    4. Ex vivo motility contrast imaging

      Ex vivo motility contrast imaging
      In a method for ex vivo evaluation of tissue response, a target biological sample is placed in a chamber of a sample holder. Biodynamic imaging (BDI) is performed on the sample to extract BDI data of the entire sample, optical coherence imaging (OCI) data is generated from the BDI data; and then motility contrast imaging (MCI) data is generated from the OCI data. The MCI data is used to select ...
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    5. Multi-Modality Imaging Enables Detailed Hemodynamic Simulations in Dissecting Aneurysms in Mice

      Multi-Modality Imaging Enables Detailed Hemodynamic Simulations in Dissecting Aneurysms in Mice
      A multi-modality imaging-based modeling approach was used to study complex unsteady hemodynamics and lesion growth in a dissecting abdominal aortic aneurysm model. We combined in vivo ultrasound (geometry and flow) and in vitro optical coherence tomography (OCT) (geometry) to obtain the high resolution needed to construct detailed hemodynamic simulations over large portions of the murine vasculature, which include fine geometric complexities. We illustrate this approach for a spectrum of dissecting ...
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    6. Microstructural characterization of myocardial infarction with optical coherence tractography and two‐photon microscopy

      Microstructural characterization of myocardial infarction with optical coherence tractography and two‐photon microscopy
      Myocardial infarction leads to complex changes in the fiber architecture of the heart. Here, we present a novel optical approach to characterize these changes in intact hearts in three dimensions. Optical coherence tomography (OCT) was used to derive a depth‐resolved field of orientation on which tractography was performed. Tractography of healthy myocardium revealed a smooth linear transition in fiber inclination or helix angle from the epicardium to endocardium. Conversely ...
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    7. Fingerprint Matching with Optical Coherence Tomography

      Fingerprint Matching with Optical Coherence Tomography
      Fingerprint recognition is an important security technique with a steadily growing usage for the identification and verification of individuals. However, current fingerprint acquisition systems have certain disadvantages, which include the requirements of physical contact with the acquisition device, and the presence of undesirable artefacts, such as scars, on the surface of the fingerprint. This paper evaluates the accuracy of a complete framework for the capturing of undamaged, undistorted fingerprints from ...
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    8. Adaptive-optics optical coherence tomography processing using a graphics processing unit

      Adaptive-optics optical coherence tomography processing using a graphics processing unit
      Graphics processing units are increasingly being used for scientific computing for their powerful parallel processing abilities, and moderate price compared to super computers and computing grids. In this paper we have used a general purpose graphics processing unit to process adaptive-optics optical coherence tomography (AOOCT) images in real time. Increasing the processing speed of AOOCT is an essential step in moving the super high resolution technology closer to clinical viability.
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    9. Live tissue viability and chemosensitivity assays using digital holographic motility contrast imaging

      Live tissue viability and chemosensitivity assays using digital holographic motility contrast imaging
      Holographic optical coherence imaging is an en face form of optical coherence tomography that uses low-coherence digital holography as a coherence gate to select light from a chosen depth inside scattering tissue. By acquiring successive holograms at a high camera frame rate at a fixed depth, dynamic speckle provides information concerning dynamic light scattering from intracellular motility. Motility contrast imaging (MCI) uses living motion as a label-free and functional biomarker ...
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    10. Nicolaus Copernicus University, Toruń, Poland offers scholarships of 3,500 PLN for 3 PhD students, within the frames of TEAM program.

      Nicolaus Copernicus University, Toruń, Poland offers scholarships of 3,500 PLN for 3 PhD students, within the frames of TEAM program.
      ...ey will collaborate with two very dynamic and very efficient research groups lead by prof. Alexander Wei from Purdue University and prof. Robert Huber from Ludwig Maximilians University in Munich. Requirements Candid...
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    11. Nicolaus Copernicus University, Toruń, Poland offers scholarships of 1,000 PLN for 2 students, within the frames of TEAM program.

      Nicolaus Copernicus University, Toruń, Poland offers scholarships of 1,000 PLN for 2 students, within the frames of TEAM program.
      ...ey will collaborate with two very dynamic and very efficient research groups lead by prof. Alexander Wei from Purdue University and prof. Robert Huber from Ludwig Maximilians University in Munich. Requirements Candidat...
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    12. Nicolaus Copernicus University has vacancies for 2 post-doc positions funded for a period of 36 months

      Nicolaus Copernicus University has vacancies for 2 post-doc positions funded for a period of 36 months
      ...ey will collaborate with two very dynamic and very efficient research groups lead by prof. Alexander Wei from Purdue University and prof. Robert Huber from Ludwig Maximilians University in Munich. Requirements Candid...
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    13. Optical Interferometry for Biology and Medicine (Book)

      Optical Interferometry for Biology and Medicine (Book)
      This book presents the fundamental physics of optical interferometry as applied to biophysical, biological and medical research. Interference is at the core of many types of optical detection and is a powerful probe of cellular and tissue structure in interfererence microscopy and in optical coherence tomography. It is also the root cause of speckle and other imaging artefacts that limit range and resolution. For biosensor applications, the inherent sensitivity of ...
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    14. 1-15 of 30 1 2 »
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  2. About Purdue University

    Purdue University

    Purdue University, located in West Lafayette, Indiana, U.S., is the flagship university of the six campuses within the Purdue University System. Purdue offers both undergraduate and graduate programs in over 200 major areas of study. The university has been influential in America's history of aviation, having established the first college credit offered in flight training, the first four-year bachelor's degree in aviation, and the first university airport (Purdue University Airport).