1. Praveen J. Patel

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    1. Mentioned In 36 Articles

    2. Association of ambient air pollution with age-related macular degeneration and retinal thickness in UK Biobank

      Association of ambient air pollution with age-related macular degeneration and retinal thickness in UK Biobank
      Aim To examine the associations of air pollution with both self-reported age-related macular degeneration (AMD), and in vivo measures of retinal sublayer thicknesses. Methods We included 115954 UK Biobank participants aged 4069 years old in this cross-sectional study. Ambient air pollution measures included particulate matter, nitrogen dioxide (NO 2 ) and nitrogen oxides (NO x ). Participants with self-reported ocular conditions, high refractive error ( 6 or +6 diopters) and poor spectral-domain optical ...
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    3. Phenotyping of retinal neovascularization in ischemic retinal vein occlusion using wide field OCT angiography

      Phenotyping of retinal neovascularization in ischemic retinal vein occlusion using wide field OCT angiography
      Background/objectives Abnormal retinal neovascularization caused by ischemic retinal vein occlusion (RVO) is a frequent cause of visually significant vitreous hemorrhage. The early detection of new vessels may be challenging and often requires the use of invasive tests such as fundus fluorescein angiography (FA). We demonstrate the use of wide-field optical coherence tomography angiography (WF-OCTA) in the detection and characterization of neovascularization secondary to ischemic RVO. Subjects/methods We conducted ...
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    4. Investigation of the efficacy of an online tool for improving the diagnosis of macular lesions imaged by optical coherence tomography

      Investigation of the efficacy of an online tool for improving the diagnosis of macular lesions imaged by optical coherence tomography
      Purpose: Optical coherence tomography (OCT) is a non-invasive method for diagnosis and monitoring of retinal (typically, macular) conditions. The unfamiliar nature of OCT images can present considerable challenges for some community optometrists. The purpose of this research is to develop and assess the efficacy of a novel internet resource designed to assist optometrists in using OCT for diagnosis of macular disease and patient management. Methods: An online tool (OCTAID) has ...
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    5. Widefield optical coherence tomography angiography for early detection and objective evaluation of proliferative diabetic retinopathy

      Widefield optical coherence tomography angiography for early detection and objective evaluation of proliferative diabetic retinopathy
      Purpose To evaluate the utility of widefield optical coherence tomography angiography (WF-OCTA) compared with clinical examination in grading diabetic retinopathy in patients diagnosed clinically with proliferative diabetic retinopathy (PDR) or severe non-proliferative diabetic retinopathy (NPDR). Design This retrospective observational case series included patients diagnosed clinically with PDR or severe NPDR. Patients underwent standard clinical examination and WF-OCTA imaging (PLEX Elite 9000, Carl Zeiss Meditec AG) using 1212 montage scans between ...
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    6. The Relationship Between Ambient Atmospheric Fine Particulate Matter (PM2.5) and Glaucoma in a Large Community Cohort

      The Relationship Between Ambient Atmospheric Fine Particulate Matter (PM2.5) and Glaucoma in a Large Community Cohort
      Purpose : Glaucoma is more common in urban populations than in others. Ninety percent of the world's population are exposed to air pollution above World Health Organization (WHO) recommended limits. Few studies have examined the association between air pollution and glaucoma. Methods : Questionnaire data, ophthalmic measures, and ambient residential area air quality data for 111,370 UK Biobank participants were analyzed. Particulate matter with an aerodynamic diameter 2.5 m ...
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    7. Objective evaluation of proliferative diabetic retinopathy using optical coherence tomography

      Objective evaluation of proliferative diabetic retinopathy using optical coherence tomography
      Purpose To present the routine use of optical coherence tomography (OCT) and OCT angiography (OCTA) for the objective diagnosis and monitoring of proliferative diabetic retinopathy (PDR). Design Retrospective observational case series. Subjects Patients with diabetic retinopathy imaged using a standardized PDR-protocol Methods Patients routinely imaged with a standardized PDR-protocol between March 2017 and January 2019 were included. This included a 12x9 mm structural OCT volume centered on the macula and ...
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    8. Effect of total anti-VEGF treatment exposure on patterns of choroidal neovascularisation assessed by optical coherence tomography angiography in age-related macular degeneration: a retrospective case series

      Effect of total anti-VEGF treatment exposure on patterns of choroidal neovascularisation assessed by optical coherence tomography angiography in age-related macular degeneration: a retrospective case series
      Objective To compare clinical characteristics of patients suffering from neovascular age-related macular degeneration (nAMD) with mature and immature choroidal neovascularisation (CNV) as assessed by optical coherence tomography angiography (OCTA). To explore the effect of total anti-vascular endothelial growth factor exposure on the occurrence of mature CNV when correcting for potential confounders. Methods and analysis In this retrospective case series, we included 40 eyes of 36 patients with nAMD with CNV ...
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    9. Swept‐source optical coherence tomography angiography features of subretinal fibrosis in neovascular age‐related macular degeneration

      Swept‐source optical coherence tomography angiography features of subretinal fibrosis in neovascular age‐related macular degeneration
      Importance The study highlights the role of Optical Coherence Angiography in the management of patients with neovascular age‐related macular degeneration who have developed subretinal fibrosis. Background Development of subretinal fibrosis in the context of neovascular age‐related macular degeneration is known to adversely affect visual function. The aim of this study is to assess structure and flow features obtained through swept‐source optical coherence tomography angiography in patients with ...
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    10. Feature Of The Week 07/08/2018: Retinal Nerve Fibre Layer Thickness & Cognition - Results from UK Biobank

      Feature Of The Week 07/08/2018: Retinal Nerve Fibre Layer Thickness & Cognition - Results from UK Biobank
      ...l NHS Foundation Trust and UCL Institute of Ophthalmology. For more information see recent Article. Courtesy Praveen Patel from Moorfields Eye Hospital and the NIHR Biomedical Research Centre at Moorfields Eye Hospital ...
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    11. Association of Retinal Nerve Fiber Layer Thinning With Current and Future Cognitive Decline A Study Using Optical Coherence Tomography

      Association of Retinal Nerve Fiber Layer Thinning With Current and Future Cognitive Decline A Study Using Optical Coherence Tomography
      ... Eoin O’Sullivan, MD, King's College Hospital NHS Foundation Trust, Chris G. Owen, PhD, University of London, Praveen Patel, FRCOphth, NIHR Biomedical Research Centre, Euan Paterson, BSc, Queens University Belfast, Tunde...
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    12. Characteristic optical coherence tomography findings in patients with primary vitreoretinal lymphoma: a novel aid to early diagnosis

      Characteristic optical coherence tomography findings in patients with primary vitreoretinal lymphoma: a novel aid to early diagnosis
      Background The diagnosis of primary vitreoretinal lymphoma (PVRL) poses significant difficulties; presenting features are non-specific and confirmation usually necessitates invasive vitreoretinal biopsy. Diagnosis is often delayed, resulting in increased morbidity and mortality. Non-invasive imaging modalities such as spectral domain optical coherence tomography (SD-OCT) offer simple and rapid aids to diagnosis. We present characteristic SD-OCT images of patients with biopsy-positive PVRL and propose a number of typical features, which we believe ...
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    13. Agreement of swept-source and spectral-domain optical coherence-tomography retinal thickness measurements in neovascular age-related macular degeneration

      Agreement of swept-source and spectral-domain optical coherence-tomography retinal thickness measurements in neovascular age-related macular degeneration
      Changes in macular thickness measurements in neovascular age-related macular degeneration (nAMD) are thought to reflect disease activity, and can be used to guide treatment with antiangiogenic agents. 1 Both spectral-domain optical coherence tomography (SD-OCT) and the more recently introduced swept-source optical coherence tomography (SS-OCT) have onboard segmentation algorithms that deliver automated retinal thickness measurements. Agreement between OCT derived macular thickness measurements is critical for monitoring of patients if these modalities ...
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    14. Impact of retinal pigment epithelium pathology on spectral-domain optical coherence tomography-derived macular thickness and volume metrics and their intersession repeatability

      Impact of retinal pigment epithelium pathology on spectral-domain optical coherence tomography-derived macular thickness and volume metrics and their intersession repeatability
      Background To determine the impact of retinal pigment epithelium (RPE) pathology on intersession repeatability of retinal thickness and volume metrics derived from Spectralis spectral-domain optical coherence tomography (SD-OCT). Design Prospective cross-sectional single centre study. Participants 56 eyes of 56 subjects were divided into 3 groups: (A) normal RPE band (25 eyes), (B) RPE elevation: macular soft drusen (13 eyes) and (C) RPE attenuation: geographic atrophy or inherited retinal diseases (18 ...
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    15. Optical Coherence Tomography in the UK Biobank Study – Rapid Automated Analysis of Retinal Thickness for Large Population-Based Studies

      Optical Coherence Tomography in the UK Biobank Study – Rapid Automated Analysis of Retinal Thickness for Large Population-Based Studies
      Purpose To describe an approach to the use of optical coherence tomography (OCT) imaging in large, population-based studies, including methods for OCT image acquisition, storage, and the remote, rapid, automated analysis of retinal thickness. Methods In UK Biobank, OCT images were acquired between 2009 and 2010 using a commercially available spectral domain OCT device (3D OCT-1000, Topcon). Images were obtained using a raster scan protocol, 6 mm x 6 mm ...
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    16. Repeatability of swept-source optical coherence tomography retinal and choroidal thickness measurements in neovascular age-related macular degeneration

      Repeatability of swept-source optical coherence tomography retinal and choroidal thickness measurements in neovascular age-related macular degeneration
      Background The aim was to determine the intrasession repeatability of swept-source optical coherence tomography (SS-OCT)-derived retinal and choroidal thickness measurements in eyes with neovascular age-related macular degeneration (nAMD). Methods A prospective study consisting of patients with active nAMD enrolled in the Distance of Choroid Study at Moorfields Eye Hospital, London. Patients underwent three 129 mm macular raster scans using the deep range imaging (DRI) OCT-1 SS-OCT (Topcon) device in ...
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    17. 1-15 of 36 1 2 3 »
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  2. About Praveen J. Patel

    Praveen J. Patel

    Praveen Patel is a consultant ophthalmologist in the Medical Retina Service at Moorfields Eye Hospital, London and Ophthalmology Specialty Lead at the NIHR Clinical Research Network, North Thames. He undertook two fellowships after his initial medical training at Cambridge University; a clinical research fellowship at Moorfields Eye Hospital and the UCL Institute of Ophthalmology, and a medical retina fellowship at Moorfields Eye Hospital. As one of the lead investigators of a pioneering trial involving anti-VEGF agents for the treatment of age-related macular degeneration, he won the Moorfields Research Medal in 2011. Praveen has a particular research interest in optimising treatment outcomes for patients with neovascular age-related macular degeneration in clinical settings and he is lead researcher for OCT in Health and Disease, an analysis of macular OCT images collected as part of the UK Biobank Resource.