1. Pooja Godara

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    1-11 of 11
    1. Mentioned In 11 Articles

    2. Assessing Retinal Structure in Patients with Parkinson Disease

      Assessing Retinal Structure in Patients with Parkinson Disease
      Objective : The retina is an extension of the central nervous system (CNS), and ocular symptoms can precede manifestations of CNS disorders. Given that several neurodegenerative conditions that affect the brain exhibit ocular symptoms, the retina may be an accessible biomarker to monitor disease progression. Dopamine, the key neurotransmitter related to Parkinsons disease (PD), is contained in amacrine and interplexiform cells, which reside in specific retinal layers. Understanding how loss of ...
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    3. RefMoB, a Reflectivity Feature Model-Based Automated Method for Measuring Four Outer Retinal Hyperreflective Bands in Optical Coherence Tomography

      RefMoB, a Reflectivity Feature Model-Based Automated Method for Measuring Four Outer Retinal Hyperreflective Bands in Optical Coherence Tomography
      Purpose. : To validate a model-driven method (RefMoB) of automatically describing the four outer retinal hyperreflective bands revealed by spectral-domain optical coherence tomography (SDOCT), for comparison with histology of normal macula; to report thickness and position of bands, particularly band 2 (ellipsoid zone [EZ], commonly called IS/OS). Methods. : Foveal and superior perifoveal scans of seven SDOCT volumes of five individuals aged 28 to 69 years with healthy maculas were used ...
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    4. Evaluation of Normal Human Foveal Development Using Optical Coherence Tomography and Histologic Examination

      Evaluation of Normal Human Foveal Development Using Optical Coherence Tomography and Histologic Examination
      Objective To assess outer retinal layer maturation during late gestation and early postnatal life using optical coherence tomography and histologic examination. Methods Thirty-nine participants 30 weeks' postmenstrual age or older were imaged using a handheld optical coherence tomography system, for a total of 102 imaging sessions. Foveal images from 16 participants (21 imaging sessions) were normal and evaluated for inner retinal excavation and the presence of outer retinal reflective bands ...
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    5. Assessing the Photoreceptor Mosaic over Drusen Using Adaptive Optics and SD-OCT

      Assessing the Photoreceptor Mosaic over Drusen Using Adaptive Optics and SD-OCT
      Drusen are extracellular deposits that accumulate between the retinal pigment epithelium and Bruchs membrane. They are one of the earliest clinical manifestations of age-related macular degeneration and it is thought that they disrupt the overlying photoreceptors, leading to subsequent vision loss. The purpose of this study was to illustrate how spectral domain optical coherence tomography and adaptive optics fundus imaging can be used to quantitatively analyze the integrity of the ...
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    6. Adaptive Optics Retinal Imaging: Emerging Clinical Applications

      Adaptive Optics Retinal Imaging: Emerging Clinical Applications
      The human retina is a uniquely accessible tissue. Tools like scanning laser ophthalmoscopy and spectral domain-optical coherence tomography provide clinicians with remarkably clear pictures of the living retina. Although the anterior optics of the eye permit such non-invasive visualization of the retina and associated pathology, the same optics induce significant aberrations that obviate cellular-resolution imaging in most cases. Adaptive optics (AO) imaging systems use active optical elements to compensate for ...
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    7. Spectral Domain Optical Coherence Tomography and Adaptive Optics: Imaging Photoreceptor Layer Morphology to Interpret Preclinical Phenotypes

      Spectral Domain Optical Coherence Tomography and Adaptive Optics: Imaging Photoreceptor Layer Morphology to Interpret Preclinical Phenotypes
      Recent years have seen the emergence of advances in imaging technology that enable in vivo evaluation of the living retina. Two of the more promising techniques, spectral domain optical coherence tomography (SD-OCT) and adaptive optics (AO) fundus imaging provide complementary views of the retinal tissue. SD-OCT devices have high axial resolution, allowing assessment of retinal lamination, while the high lateral resolution of AO allows visualization of individual cells. The potential ...
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    8. Spectral-Domain Optical Coherence Tomography and Adaptive Optics May Detect Hydroxychloroquine Retinal Toxicity Before Symptomatic Vision Loss

      Spectral-Domain Optical Coherence Tomography and Adaptive Optics May Detect Hydroxychloroquine Retinal Toxicity Before Symptomatic Vision Loss
      ...NAL TOXICITY BEFORE SYMPTOMATIC VISION LOSS BY Kimberly E. Stepien MD*, Dennis P. Han MD, Jonathan Schell MD, Pooja Godara MD, Jungtae Rha PhD, AND Joseph Carroll PhD ABSTRACT Purpose: To describe spectral-domain optica...
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  2. About Pooja Godara

    Pooja Godara is with the Ophthalmology Department at the Medical College of Wisconsin.