Purpose:To determine whether the minimum intensity of the optical coherence tomography (OCT) A-scans within the retina can predict locations of growth at the margin of geographic atrophy (GA) and the growth rate outside the margin. Methods:OCT scans were analyzed at baseline and 52 weeks. Expert graders manually segmented OCT images of GA. The 52-week follow-up scans were registered to the baseline scan coordinates for comparison. OCT Minimum Intensity (MI) values were studied within a 180-micron margin around the boundary of GA at baseline. Baseline MI values were compared in areas of progression and non-progression of the GA, and ...

The First international meeting on “en face”OCT in Rome Saturday December 14. Co-organizers are Bruno Lumbroso (Rome) Philip Rosenfeld (Miami) and Gabriel Coscas (Paris). Duration one day. We will discuss next developments of clinical “en face” OCT and clinical applications of this technique. For more information click HERE . Meeting Site ( www.symposiacongressi.eu and secretariat anna.porro@symposiacongressi.eu )).

Purpose: To evaluate drusenoid retinal pigment epithelial detachments (DPED) secondary to age-related macular degeneration (AMD) using spectral-domain optical coherence tomography imaging. Methods: In this prospective natural history study, eyes from patients with the diagnosis of nonexudative AMD and DPEDs were followed for at least 6 months. Eyes were scanned using the Cirrus spectral-domain optical coherence tomography instrument and the 200 x 200 A-scan raster pattern. A custom software was used to quantify volumetric changes in DPEDs and to detect the evolution and formation of geographic atrophy and choroidal neovascularization. Changes in DPED area and volume and development of the advanced ...

Purpose: To compare the measurements of drusen area from manual segmentation of color fundus photographs with those generated by an automated algorithm designed to detect elevations of the retinal pigment epithelium (RPE) on spectral domain optical coherence tomography (SDOCT) images. Methods: Fifty eyes with drusen secondary to non-exudative age-related macular degeneration (AMD) were enrolled. All eyes were imaged with the Cirrus HD-OCT instrument (Carl Zeiss Meditec, Dublin, CA) using a 200x200 A-scan raster pattern covering a 6mm X 6mm area centered on the fovea. Digital color fundus images were taken on the same day. Drusen were traced manually on the ...

BACKGROUND AND OBJECTIVE: To investigate the performance of an automated foveal center detection algorithm on spectral-domain optical coherence tomography (SD-OCT). PATIENTS AND METHODS: Fifty normal eyes and 50 eyes with early stage dry age-related macular degeneration (AMD) were analyzed. The actual scan center (SC), automatically detected foveal center (AF), and manually identified foveal center (MF) were compared. RESULTS: The mean of the radial distances was 89 ± 120 μm from MF to SC and 54 ± 41 μm from MF to AF for normal eyes and 179 ± 125 μm from SC to MF and 104 ± 62 μm from AF to MF for ...