1. Peter R. Eastwood

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    1. Mentioned In 19 Articles

    2. Does smooth muscle in an intact airway undergo length adaptation during a sustained change in transmural pressure?

      Does smooth muscle in an intact airway undergo length adaptation during a sustained change in transmural pressure?
      ...ange in transmural pressure? Thomas K. Ansell , Peter K. McFawn , Robert A. McLaughlin , David D. Sampson , Peter R. Eastwood , David R. Hillman , Howard W. Mitchell , Peter B. Noble Journal of Applied Physiology Publi...
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    3. Effect of the velopharynx on intraluminal pressures in reconstructed pharynges derived from individuals with and without sleep apnea

      Effect of the velopharynx on intraluminal pressures in reconstructed pharynges derived from individuals with and without sleep apnea
      ...r Microscopy, Characterisation & Analysis, The University of Western Australia, Perth, WA 6009, Australia , * Peter R. Eastwood Affiliations + West Australian Sleep Disorders Research Institute, Department of Pulmonary P...
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    4. Phenotyping Airways Disease With Optical Coherence Tomography

      Phenotyping Airways Disease With Optical Coherence Tomography
      Airway diseases are a major concern around the world. However, the pace of new drug and biomarker discovery has lagged behind those of other common disorders such as cardiovascular diseases and diabetes. One major barrier in airways research has been the inability to accurately visualize large and small airway remodeling or dysplastic/neoplastic (either pre or early cancerous) changes using non or minimally invasive instruments. The advent of optical coherence ...
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    5. Elastic Properties of the Central Airways in Obstructive Lung Diseases Measured Using Anatomical Optical Coherence Tomography

      Elastic Properties of the Central Airways in Obstructive Lung Diseases Measured Using Anatomical Optical Coherence Tomography
      Rationale: Our understanding of how airway remodeling affects regional airway elastic properties is limited due to technical difficulties in quantitatively measuring dynamic, in vivo airway dimensions. Such knowledge could help elucidate mechanisms of excessive airway narrowing. Objectives: To utilize anatomical optical coherence tomography (aOCT) to compare central airway elastic properties in control subjects and those with obstructive lung diseases. Methods: Following bronchodilation, airway lumen area (Ai) was measured using aOCT ...
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    6. Distribution of airway narrowing responses across generations and at branching points, assessed in vitro by anatomical optical coherence tomography

      Distribution of airway narrowing responses across generations and at branching points, assessed in vitro by anatomical optical coherence tomography
      Background Previous histological and imaging studies have shown the presence of variability in the degree of bronchoconstriction of airways sampled at different locations in the lung (i.e., heterogeneity). Heterogeneity can occur at different airway generations and at branching points in the bronchial tree. Whilst heterogeneity has been detected by previous experimental approaches its spatial relationship either within or between airways is unknown. Methods In this study, distribution of airway ...
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    7. Airway Narrowing Assessed by Anatomical Optical Coherence Tomography In Vitro: Dynamic Airway Wall Morphology and Function

      Airway Narrowing Assessed by Anatomical Optical Coherence Tomography In Vitro: Dynamic Airway Wall Morphology and Function
      Regulation of airway caliber by lung volume or bronchoconstrictor stimulation is dependent on physiological, structural and mechanical events within the airway wall, including airway smooth muscle (ASM) contraction, deformation of the mucosa and cartilage, and tensioning of elastic matrices linking wall components. Despite close association between events in the airway wall and the resulting airway caliber these have typically been studied separately: the former primarily using histological approaches, the latter ...
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    8. Quantifying tracheobronchial tree dimensions: methods, limitations and emerging techniques

      ...ques J. P. Williamson^1^,2, A. L. James^1^,3^,4, M. J. Phillips^5, D. D. Sampson^6, D. R. Hillman^1^,3 and P. R. Eastwood^1^,2^,3 Depts of ^1 Pulmonary Physiology, and ^5 Respiratory Medicine, Sir Charles Gairdner Hos...
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    9. Measuring airway dimensions during bronchoscopy using anatomical optical coherence tomography

      Airway dimensions are difficult to quantify bronchoscopically because of optical distortion and a limited ability to gauge depth. Anatomical optical coherence tomography (aOCT), a novel imaging technique, may overcome these limitations. This study evaluated the accuracy of aOCT against existing techniques in phantom, excised pig and in vivo human airways. Three comparative studies were performed: (i) micrometer-derived area measurements in ten plastic tubes were compared to aOCT-derived area; (ii) aOCT-derived ...
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    10. A Method Of Providing Quantitative Information About The Lower Airways Of A Lung (Wo 2009/059368)

      A Method Of Providing Quantitative Information About The Lower Airways Of A Lung (Wo 2009/059368)
      The present disclosure provides a method of providing quantitative information about a property of the lower airways of a lung using optical coherence tomography. The method comprises inserting a probe head of an anatomical optical coherence tomography device into the lower airways. Further, the method comprises directing light to, and receiving reflected light from, an internal wall portion of the lower airways. The light is suitable for optical coherence tomography ...
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    11. Effect of Body Posture on Pharyngeal Shape and Size in Adults With and Without Obstructive Sleep Apnea

      ... Kathleen J. Maddison, BSc (Hons)1; Julian J. Armstrong, PhD2; David D. Sampson, PhD2; David R. Hillman, MD1; Peter R. Eastwood, PhD1,3 1West Australian Sleep Disorders Research Institute, Sir Charles Gairdner Hospital, ...
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    12. 1-15 of 19 1 2 »
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  2. About Peter R. Eastwood

    Peter R. Eastwood

    Peter R. Eastwood is with the Department of Pulmonary Physiology at Sir Charles Gairdner Hospital, the School of Anatomy & Human Biology at University of Western Australia, the West Australian Sleep Disorders Research Institute at Sir Charles Gairdner Hospital.