1. Peter K. Kaiser

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    1. Mentioned In 64 Articles

    2. Optical coherence tomography angiography characteristics of choroidal neovascularization requiring varied dosing frequencies in treat-and-extend management: An analysis of the AVATAR study

      Optical coherence tomography angiography characteristics of choroidal neovascularization requiring varied dosing frequencies in treat-and-extend management: An analysis of the AVATAR study
      Purpose To evaluate optical coherence tomography angiography (OCTA) characteristics of choroidal neovascularization (CNV) in eyes requiring different treatment frequency of anti-vascular endothelial growth factor (VEGF) therapy for neovascular age-related macular degeneration (NVAMD). Design Prospective observational case series. Methods Subjects who had undergone anti-VEGF treatment for NVAMD in the AVATAR study were subdivided into 3 groups depending on required anti-VEGF dosing: (i) treat-and-extend requiring every 46 weeks dosing (TEq4-6w), (ii) treat-and-extend ...
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    3. IMPACT OF OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY REVIEW STRATEGY ON DETECTION OF CHOROIDAL NEOVASCULARIZATION

      IMPACT OF OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY REVIEW STRATEGY ON DETECTION OF CHOROIDAL NEOVASCULARIZATION
      Purpose: To compare optical coherence tomography angiography ( OCTA ) review strategies for optimizing choroidal neovascularization ( CNV ) detection . Methods: Eyes with CNV in the differential diagnosis were imaged with the Avanti RTVue XR HD (Optovue, Fremont, CA). Three modalities of review for CNV presence were used in each case: a single report generated using automated segmentation within Avanti software; a continuous slab descent video OCTA export; and a manual segmentation approach using ...
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    4. The DISCOVER Study 3-Year Results

      The DISCOVER Study 3-Year Results
      Purpose To report the 3-year assessment of feasibility and usefulness of microscope-integrated intraoperative OCT (iOCT) during ophthalmic surgery. Design Prospective, consecutive case series. Participants Adult participants undergoing incisional ophthalmic surgery with iOCT imaging who consented to be enrolled in the Determination of Feasibility of Intraoperative Spectral-Domain Microscope Combined/Integrated OCT Visualization during En Face Retinal and Ophthalmic Surgery (DISCOVER) study. Methods The DISCOVER study is a single-site, multisurgeon, institutional review ...
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    5. Comparison of OCT Angiography Review Strategies to Identify Vascular Abnormalities in the AVATAR Study

      Comparison of OCT Angiography Review Strategies to Identify Vascular Abnormalities in the AVATAR Study
      Purpose To compare review strategies for OCT angiography (OCTA) for multiple disease features found in common diseases of the choroid and retina. Design Prospective, observational study. Participants Patients with macular disease undergoing routine spectral-domain OCT. Methods Eyes were imaged with the Avanti RTVue XR HD (Optovue, Fremont, CA), and the split-spectrum amplitude decorrelation angiography algorithm software was used for OCTA performance. Scans were reviewed by 2 masked expert reviewers. A ...
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    6. Cleveland Clinic Receives a NIH Grant for Intraoperative Optical Coherence Tomography for Ophthalmic Surgery

      Cleveland Clinic Receives a NIH Grant for Intraoperative Optical Coherence Tomography for Ophthalmic Surgery
      ...l career as an independent clinician-scientist. Dr. Ehlers has assembled an outstanding mentorship team (Drs. Peter Kaiser, Cynthia Toth, and William J. Dupps). The mentors' experience in instrument design, biomedical en...
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    7. Outcomes of Intraoperative OCT–Assisted Epiretinal Membrane Surgery from the PIONEER Study

      Outcomes of Intraoperative OCT–Assisted Epiretinal Membrane Surgery from the PIONEER Study
      Purpose To assess the retinal architecture changes that occur during epiretinal membrane (ERM) surgery, utilizing intraoperative OCT ( i OCT). Design Prospective multisurgeon single-center study. Subjects Subjects from the PIONEER i OCT study who underwent surgical intervention for management of ERM. Methods All subjects underwent vitrectomy with ERM peeling with optional internal limiting membrane (ILM) peeling. Preoperative, intraoperative, and postoperative quantitative and qualitative OCT assessments were performed. Clinical characteristics including visual ...
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    8. Optical Coherence Tomography Features in Diabetic Macular Edema and the Impact on Anti-VEGF Response

      Optical Coherence Tomography Features in Diabetic Macular Edema and the Impact on Anti-VEGF Response
      BACKGROUND AND OBJECTIVE: To assess the relationship between spectral-domain optical coherence tomography (SD-OCT) features and functional outcomes for diabetic macular edema (DME) undergoing treatment with intravitreal bevacizumab (Avastin; Genentech, South San Francisco, CA). PATIENTS AND METHODS: Institutional review board-approved, retrospective, consecutive case series of eyes receiving intravitreal bevacizumab (1.25 mg) for DME. SD-OCT features were evaluated and correlated with functional response to anti-vascular endothelial growth factor (VEGF) therapy. RESULTS ...
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    9. Choroidal neovascularisation on optical coherence tomography angiography in punctate inner choroidopathy and multifocal choroiditis

      Choroidal neovascularisation on optical coherence tomography angiography in punctate inner choroidopathy and multifocal choroiditis
      Purpose To describe the findings seen on optical coherence tomography angiography (OCTA) in patients with punctate inner choroidopathy (PIC) and multifocal choroiditis and panuveitis (MCP) complicated by choroidal neovascular membranes. Methods This was an Institutional Review Board-approved prospective, descriptive case series. 12 patients with PIC and MCP complicated by choroidal neovascularisation (CNV) were included. Each patient underwent slit-lamp examination by a uveitis specialist followed by conventional spectral domain OCT imaging ...
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    10. Volumetric analysis of pathologies

      Volumetric analysis of pathologies
      Systems and methods are provided for volumetric analysis of pathologies. A segmentation component is configured to determine, for each of a series of images of a region of interest containing a pathological feature, a set of segmentation boundaries within the image representing a cross-section of the pathological feature. A mesh generation component is configured to link the sets of segmentation boundaries from adjacent images in the series of images to ...
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    11. Optical Coherence Tomography for the Detection of Remote Optic Neuritis in Multiple Sclerosis

      Optical Coherence Tomography for the Detection of Remote Optic Neuritis in Multiple Sclerosis
      BACKGROUND AND PURPOSE Evidence of remote optic neuritis is often used to support a diagnosis of multiple sclerosis (MS). Optical coherence tomography (OCT) can provide qualitative and quantitative data on the retina, where the effects of optic neuritis can be seen. Our aim was to determine whether there is a quantitative difference in retinal structures in eyes with optic neuritis compared with those without, and which measures were best able ...
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      Mentions: Peter K. Kaiser
    12. Brave New World: OCT Angiography A Video: Dr. Reichel Reviews OCTA with Drs. Prenner and Kaiser

      Brave New World: OCT Angiography A Video: Dr. Reichel Reviews OCTA with Drs. Prenner and Kaiser
      Elias Reichel, MD, joined Jonathan L. Prenner, MD, and Richard S. Kaiser, MD, for a recent installment of the Retina Today Journal Club. He answered their questions about an imaging technology that will soon be commercially available: optical coherence tomography angiography (OCTA). Dr. Kaiser noted that when many retina doctors first trained, they relied on fluorescein angiography (FA), which offered a limited view of the fundus, before relying on OCT ...
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    13. Anterior segment spectral domain optical coherence tomography imaging of patients with anterior scleritis

      Anterior segment spectral domain optical coherence tomography imaging of patients with anterior scleritis
      The purpose of the study was to describe the findings seen on anterior segment spectral domain optical coherence tomography (SD-OCT) in patients with anterior scleritis and determine the feasibility of using SD-OCT to image and grade the degree of scleral inflammation and monitor response to treatment. All patients underwent slit lamp examination by a uveitis specialist, and the degree of scleral inflammation was recorded. Spectral domain OCT imaging was then ...
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    14. Membrane Peeling-Induced Retinal Alterations on Intraoperative OCT in Vitreomacular Interface Disorders From the PIONEER Study

      Membrane Peeling-Induced Retinal Alterations on Intraoperative OCT in Vitreomacular Interface Disorders From the PIONEER Study
      Purpose : To assess retinal architectural alterations that occur following membrane peeling procedures and the impact of peel technique on these alterations utilizing intraoperative optical coherence tomography ( i OCT). Methods : This is a subanalysis of the prospective PIONEER i OCT study of eyes undergoing a membrane peeling for a vitreomacular interface (VMI) disorder. Intraoperative scanning was performed with a microscope-mounted OCT system. Macroarchitectural alterations (e.g., full-thickness retinal elevations) and microarchitectural ...
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    15. Cleveland Clinic Receives NIH Grant to Study Intraoperative Optical Coherence Tomography for Ophthalmic Surgery

      Cleveland Clinic Receives NIH Grant to Study Intraoperative Optical Coherence Tomography for Ophthalmic Surgery
      ...l career as an independent clinician-scientist. Dr. Ehlers has assembled an outstanding mentorship team (Drs. Peter Kaiser, Cynthia Toth, and William J. Dupps). The mentors' experience in instrument design, biomedical en...
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  2. About Peter K. Kaiser

    Peter K. Kaiser

    Peter K. Kaiser, M.D., is with the Cole Eye Institute, Cleveland Clinic, Cleveland, Ohio. Peter has been an ophthalmologist at the Cleveland Clinic since 1997. He specializes in vitreoretinal diseases, age-related macular degeneration, complicated retinal detachment, diabetic retinopathy and posterior segment complications of anterior segment surgery.

  3. Quotes

    1. “Now we’re at a precipice of potentially a new frontier...This technology means that retina doctors are “seeing things we never thought we would see” and “seeing things maybe we don’t even know how to interpret.
      In Brave New World: OCT Angiography A Video: Dr. Reichel Reviews OCTA with Drs. Prenner and Kaiser