Articles that mention Pearse A. Keane -Optical Coherence Tomography News

Pearse A. Keane

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1. Mentioned In 106 Articles
2. Predicting conversion to wet age-related macular degeneration using deep learning
  
  Explore Nature Publishing Group May 20 2020 Ophthalmology
  
  Progression to exudative wet age-related macular degeneration (exAMD) is a major cause of visual deterioration. In patients diagnosed with exAMD in one eye, we introduce an artificial intelligence (AI) system to predict progression to exAMD in the second eye. By combining models based on three-dimensional (3D) optical coherence tomography images and corresponding automatic tissue maps, our system predicts conversion to exAMD within a clinically actionable 6-month time window, achieving a ...
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  Mentions: University College London Pearse A. Keane
3. Widefield optical coherence tomography angiography for early detection and objective evaluation of proliferative diabetic retinopathy
  
  Explore BJO Online Mar 24 2020 Ophthalmology
  
  Purpose To evaluate the utility of widefield optical coherence tomography angiography (WF-OCTA) compared with clinical examination in grading diabetic retinopathy in patients diagnosed clinically with proliferative diabetic retinopathy (PDR) or severe non-proliferative diabetic retinopathy (NPDR). Design This retrospective observational case series included patients diagnosed clinically with PDR or severe NPDR. Patients underwent standard clinical examination and WF-OCTA imaging (PLEX Elite 9000, Carl Zeiss Meditec AG) using 1212 montage scans between ...
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  Mentions: University College London Carl Zeiss Meditec Praveen J. Patel
4. Automated Pupillometry using a Prototype Binocular Optical Coherence Tomography System
  
  Explore American Journal of Ophthalmology Feb 27 2020 Ophthalmology
  
  Purpose To determine the test-retest reliability and diagnostic accuracy of a binocular optical coherence tomography (OCT) prototype (Envision Diagnostics, USA) for pupillometry. Design Assessment of diagnostic reliability and accuracy. Methods Fifty participants with RAPD confirmed using the swinging flashlight method (mean age 49.6 years) and 50 healthy controls (mean age 31.3 years) were examined. Participants twice underwent an automated pupillometry exam using a binocular OCT system that presents ...
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  Mentions: University College London Axel Petzold Pearse A. Keane
5. Subclinical Macular Changes And Disease Laterality In Pediatric Coats Disease Determined By Quantitative Optical Coherence Tomography Angiography
  
  Explore LWW Online Nov 26 2019 Ophthalmology
  
  Purpose: To determine vascular change at the macula in both eyes in unilateral pediatric Coats disease using optical coherence tomography angiography. Methods: Retrospective case-series. Thirteen eyes of pediatric patients with a diagnosis of unilateral Coats disease of various stages were compared with 13 fellow eyes. Optical coherence tomography angiography images were acquired using the RTVue XR Avanti. Scans were analyzed with novel projection artifact removal software and improved segmentation. Vascular ...
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  Mentions: Optovue University College London Pearse A. Keane
6. Correspondence: Trends in Retina Specialist Imaging Utilization From 2012 to 2016 in the United States Medicare Fee-for-Service Population
  
  Explore American Journal of Ophthalmology Nov 14 2019 Ophthalmology
  
  We read with great interest the recent report by Wibbelsman and associates titled Trends in Retina Specialist Imaging Utilization from 2012 to 2016 in the USA Medicare fee-for-service Population.1 Despite the prominent role of optical coherence tomography (OCT) in ophthalmic practice, there is a surprising scarcity of published literature on the frequency of its application.
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  Mentions: University College London Pearse A. Keane
7. Optical coherence tomography (OCT) in unconscious and systemically unwell patients using a mobile OCT device: a pilot study
  
  Explore BMJ Open Nov 12 2019 Ophthalmology
  
  Objective This study aims to evaluate the feasibility of retinal imaging in critical care using a novel mobile optical coherence tomography (OCT) device. The Heidelberg SPECTRALIS FLEX module (Heidelberg Engineering, Heidelberg, Germany) is an OCT unit with a boom arm, enabling ocular OCT assessment in less mobile patients. Design We undertook an evaluation of the feasibility of using the SPECTRALIS FLEX for undertaking ocular OCT images in unconscious and critically ...
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  Mentions: Heidelberg Engineering Pearse A. Keane
8. Pearse Keane Q&A: how open access AI is bringing ophthalmology into focus
  
  Explore Medical Device Network Oct 16 2019 Ophthalmology
  
  Since 2016, Moorfields Eye Hospital in London has been working with DeepMind, one of the worlds leading artificial intelligence companies. Through the partnership, researchers hope to use over one million anonymised retinal images to train artificial intelligence (AI) in the automated diagnosis of optical coherence tomography (OCT) images. OCT images are extremely complex and can take clinicians a long time to analyse, which can impact how quickly patients can receive ...
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  Mentions: University College London Pearse A. Keane
9. Objective evaluation of proliferative diabetic retinopathy using optical coherence tomography
  
  Explore ScienceDirect Sep 14 2019 Ophthalmology
  
  Purpose To present the routine use of optical coherence tomography (OCT) and OCT angiography (OCTA) for the objective diagnosis and monitoring of proliferative diabetic retinopathy (PDR). Design Retrospective observational case series. Subjects Patients with diabetic retinopathy imaged using a standardized PDR-protocol Methods Patients routinely imaged with a standardized PDR-protocol between March 2017 and January 2019 were included. This included a 12x9 mm structural OCT volume centered on the macula and ...
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  Mentions: University College London Topcon Medical Systems Praveen J. Patel
10. OCT Angiography in Acute Posterior Multifocal Placoid Pigment Epitheliopathy
  
  Explore Healio.com Aug 18 2019 Ophthalmology
  
  BACKGROUND AND OBJECTIVE: To describe retinal and choroidal findings in different stages of acute posterior multifocal placoid pigment epitheliopathy (APMPPE). PATIENTS AND METHODS: Retrospective, noncomparative case series studied by fundus biomicroscopy, fundus autofluorescence (FAF), fluorescein angiography (FA), indocyanine green angiography (ICGA), spectral-domain optical coherence tomographic (SD-OCT), and swept-source OCT angiography (SS-OCTA). RESULTS: Six eyes of three patients with bilateral APMPPE were included. FAF showed multifocal, branched patches of hyperautofluorescence with ...
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  Mentions: University College London Pearse A. Keane
11. Anterior segment optical coherence tomographic angiography assessment of acute chemical injury
  
  Explore American Journal of Ophthalmology May 9 2019 Ophthalmology
  
  Purpose To compare routine clinical examination with optical coherence tomography angiography (OCTA) for the assessment of limbal conjunctival ischemia following a chemical burn. Setting Validity analysis Methods We assessed ten participants (15 eyes) with an acute chemical injury. Clinical photographs were used to determine the extent of any limbal conjunctival epithelial defect and ischemia. These were compared with the extent of limbal ischemia identified on OCTA images of the ocular ...
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  Mentions: University College London Pearse A. Keane
12. Effect of total anti-VEGF treatment exposure on patterns of choroidal neovascularisation assessed by optical coherence tomography angiography in age-related macular degeneration: a retrospective case series
  
  Explore Home | BMJ Open Ophthalmology Apr 14 2019 Ophthalmology
  
  Objective To compare clinical characteristics of patients suffering from neovascular age-related macular degeneration (nAMD) with mature and immature choroidal neovascularisation (CNV) as assessed by optical coherence tomography angiography (OCTA). To explore the effect of total anti-vascular endothelial growth factor exposure on the occurrence of mature CNV when correcting for potential confounders. Methods and analysis In this retrospective case series, we included 40 eyes of 36 patients with nAMD with CNV ...
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  Mentions: Tufts University Praveen J. Patel Nadia K. Waheed
13. Test performance of optical coherence tomography angiography in detecting retinal diseases: a systematic review and meta-analysis
  
  Explore Nature Publishing Group Apr 10 2019 Ophthalmology
  
  Objective To investigate the diagnostic accuracy of optical coherence tomography angiography (OCTA) in detecting vascular characteristics of chorio-retinal disease. Methods Evidence acquisition: We searched Web of Science, Scopus, and Medline by the citation of references and complemented these electronic searches by checking the list of references of included and review articles. Screening, selection, assessment, and extraction was performed in parallel by two authors. Results Evidence synthesis: Systematic review and exploratory ...
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  Mentions: Pearse A. Keane
14. Predicting optical coherence tomography-derived diabetic macular edema grades from fundus photographs using deep learning
  
  Explore arxiv.org Oct 31 2018 Ophthalmology
  
  Diabetic eye disease is one of the fastest growing causes of preventable blindness. With the advent of anti-VEGF (vascular endothelial growth factor) therapies, it has become increasingly important to detect center-involved diabetic macular edema. However, center-involved diabetic macular edema is diagnosed using optical coherence tomography (OCT), which is not generally available at screening sites because of cost and workflow constraints. Instead, screening programs rely on the detection of hard exudates ...
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  Mentions: University College London Pearse A. Keane
15. Artificial intelligence and deep learning in ophthalmology
  
  Explore BJO Online Oct 25 2018 Ophthalmology
  
  Artificial intelligence (AI) based on deep learning (DL) has sparked tremendous global interest in recent years. DL has been widely adopted in image recognition, speech recognition and natural language processing, but is only beginning to impact on healthcare. In ophthalmology, DL has been applied to fundus photographs, optical coherence tomography and visual fields, achieving robust classification performance in the detection of diabetic retinopathy and retinopathy of prematurity, the glaucoma-like disc ...
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  Mentions: University College London Medical University of Vienna Oregon Health & Science University
16. Clinically applicable deep learning for diagnosis and referral in retinal disease
  
  Explore Nature Publishing Group Aug 14 2018 Ophthalmology
  
  The volume and complexity of diagnostic imaging is increasing at a pace faster than the availability of human expertise to interpret it. Artificial intelligence has shown great promise in classifying two-dimensional photographs of some common diseases and typically relies on databases of millions of annotated images. Until now, the challenge of reaching the performance of expert clinicians in a real-world clinical pathway with three-dimensional diagnostic scans has remained unsolved. Here ...
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  Mentions: University College London Adnan Tufail Pearse A. Keane
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