1. Paul Mitchell

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    1. Mentioned In 18 Articles

    2. Symmetry of Retinal Parameters Measured by Spectral-domain OCT in Normal Young Adults

      Symmetry of Retinal Parameters Measured by Spectral-domain OCT in Normal Young Adults

      Purpose: To determine interocular differences in retinal parameters in a population of young adults using spectral-domain optical coherence tomography. Methods: In the Sydney Adolescent Vascular Eye Study, young adults aged 16 to 19 years received a standardized eye examination encompassing retinal photography, spectral-domain optical coherence tomography (Cirrus HD-OCT; Carl Zeiss Meditec, Dublin, CA) and best-corrected visual acuity. Interocular differences in retinal nerve fiber layer (RNFL) and macular parameters together with sex and ethnic variations for these differences were determined. Results: In the 1500 subjects tested, right eyes had thicker average RNFL than left eyes (0.3 [mu]m, P=0 ...

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    3. Retinal nerve fiber layer and optic disc measurements by spectral domain OCT: normative values and associations in young adults

      Retinal nerve fiber layer and optic disc measurements by spectral domain OCT: normative values and associations in young adults

      Purpose To determine normative values and associations of retinal nerve fiber layer (RNFL) and optic disc parameters in normal eyes measured by spectral domain optical coherence tomography (OCT). Methods In a population-based setting, 1521 young adults were examined as part of the Sydney Adolescent Vascular and Eye Study (SAVES). Their mean age was 17.3±0.6 years. RNFL and optic disc parameter measurements were made using Cirrus HD-OCT 4000. Results The average RNFL was found to be 99.4±9.6   μ m. RNFL thickness was least for the temporal quadrant (69.9±11.2   μ m), followed by the nasal ...

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    4. Measurement of Normal Optic Nerve Head Parameters

      Measurement of Normal Optic Nerve Head Parameters

      Abstract: All optic nerve pathologies, including the glaucomas and disorders such as non-arteritic ischemic optic neuropathy, affect the appearance of the optic nerve head. Morphological examination of the optic nerve head in a qualitative and quantitative manner is therefore clinically mandatory. With the advent of modern imaging modalities such as confocal scanning laser tomography and optical coherence tomography, new diagnostic avenues have opened up to further refine the examination. The new imaging devices are now becoming a major adjunct to the diagnosis and long-term management of optic nerve head pathology; before it is possible to identify an abnormal optic disk ...

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    5. Influence of diabetes on macular thickness measured using optical coherence tomography: the Singapore Indian Eye Study

      Influence of diabetes on macular thickness measured using optical coherence tomography: the Singapore Indian Eye Study

      Purpose To determine the influence of diabetes, diabetic retinopathy (DR), and other factors on macular thickness, measured using optical coherence tomography (OCT), in a population-based sample. Methods Data from the population-based Singapore Indian Eye Study were analyzed. We measured macular thickness using Stratus OCT Fast Macular Thickness scan protocol in 228 participants with diabetes mellitus (including 167 without DR, 44 with mild DR, 17 with moderate or severe DR) and 72 non-diabetic controls without macular oedema or other macular lesions. Analysis was done on right eyes. Results The mean age of participants was 60.1±10.1 years, with 53 ...

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    6. Impact of Ethnicity on the Correlation of Retinal Parameters with Axial Length

      Impact of Ethnicity on the Correlation of Retinal Parameters with Axial Length
      Purpose. To examine whether the relationship of axial length (AL) to retinal nerve fiber layer (RNFL) and macular parameters measured by optical coherence tomography (OCT) differs according to ethnicity. Methods. As part of the Sydney Myopia Study, 2353 children from grade 7 (age range, 11.1–14.4 years) completed detailed ocular examinations in the 2004–2005 school year. AL was measured with noncontact interferometry and Stratus OCT was performed (Carl Zeiss Meditec, Jena, Germany). Results. East Asian children displayed larger AL correlations with average RNFL, inferior RNFL, nasal RNFL, outer macula, and macular volume (r = −0.25, −0.36 ...
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    7. Macular and Nerve Fiber Layer Thickness in Amblyopia: The Sydney Childhood Eye Study

      Purpose: To examine macular and peripapillary retinal nerve fiber layer (RNFL) thickness in amblyopia.Design: Population-based cross-sectional study.Participants: Of 4118 children examined in the Sydney Childhood Eye Study (incorporating the Sydney Myopia Study) from 34 randomly selected primary schools and 21 secondary schools from 2003 to 2005, 3529 (85.7%) were included in this analysis. The median age of the 2 samples was 6 years (n = 1395) and 12 years (n = 2134), respectively.Methods: A detailed eye examination was conducted on all children, including determination of best-corrected visual acuity (logarithm of the minimum angle of resolution [logMAR]), autorefraction (RK-F1 ...
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    8. Birth Weight and Optic Nerve Head Parameters

      Purpose: To assess the relationship of birth weight, birth length, and head circumference as proxy markers of intrauterine growth, cup/disc ratio, and other optic disc parameters measured using optical coherence tomography (OCT). Design: Population-based cross sectional analysis. Participants: The Sydney Childhood Eye Study examined 2353 primarily 12-year-old children from 21 randomly selected secondary schools during 2003 to 2005. Methods Of 2353 children examined, 2134 (90.7%) had OCT scans (Zeiss Stratus OCT, Carl Zeiss Meditec, Dublin, CA) and are included in this study. The “fast” optic disc scan protocol was used. Birth weight, birth length, and head circumference were ...
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    9. 1-15 of 18 1 2 »
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  2. About Paul Mitchell

    Paul Mitchell

    Paul Mitchell is a medical retinal specialist and professor of ophthalmology at the University of Sydney, and Director of Ophthalmology for the Sydney West Area. His clinical work focuses on the management of AMD, diabetic and other vascular retinopathies and on systemic diseases and their effects on the eye. His research has targeted the epidemiology of eye disease and clinical aspects of retinal diseases.