1. P. Scott Carney

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    1. Mentioned In 41 Articles

    2. Computational optical coherence tomography [Invited]

      Computational optical coherence tomography [Invited]
      Optical coherence tomography (OCT) has become an important imaging modality with numerous biomedical applications. Challenges in high-speed, high-resolution, volumetric OCT imaging include managing dispersion, the trade-off between transverse resolution and depth-of-field, and correcting optical aberrations that are present in both the system and sample. Physics-based computational imaging techniques have proven to provide solutions to these limitations. This review aims to outline these computational imaging techniques within a general mathematical framework ...
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    3. Inverse scattering for frequency-scanned full-field optical coherence tomography

      Inverse scattering for frequency-scanned full-field optical coherence tomography
      Full-field optical coherence tomography (OCT) is able to image an entire en face plane of scatterers simultaneously, but typically the focus is scanned through the volume to acquire three-dimensional structure. By solving the inverse scattering problem for full-field OCT, we show it is possible to computationally reconstruct a three-dimensional volume while the focus is fixed at one plane inside the sample. While a low-numerical-aperture (NA) OCT system can tolerate defocus ...
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    4. Filtering for unwrapping noisy Doppler optical coherence tomography images for extended microscopic fluid velocity measurement range

      Filtering for unwrapping noisy Doppler optical coherence tomography images for extended microscopic fluid velocity measurement range
      ...hor: Carney@illinois.edu Yang Xu, Donald Darga, Jason Smid, Adam M. Zysk, Daniel Teh, Stephen A. Boppart, and P. Scott Carney, "Filtering for unwrapping noisy Doppler optical coherence tomography images for extended micr...
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    5. Computational adaptive optics of the human retina

      Computational adaptive optics of the human retina
      It is well known that patient-specific ocular aberrations limit imaging resolution in the human retina. Previously, hardware adaptive optics (HAO) has been employed to measure and correct these aberrations to acquire high-resolution images of various retinal structures. While the resulting aberration-corrected images are of great clinical importance, clinical use of HAO has not been widespread due to the cost and complexity of these systems. We present a technique termed computational ...
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    6. Automated interferometric synthetic aperture microscopy and computational adaptive optics for improved optical coherence tomography

      Automated interferometric synthetic aperture microscopy and computational adaptive optics for improved optical coherence tomography
      ...Illinois 61801, USA *Corresponding author: Carney@illinois.edu Yang Xu, Yuan-Zhi Liu, Stephen A. Boppart, and P. Scott Carney, "Automated interferometric synthetic aperture microscopy and computational adaptive optics fo...
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    7. Polarization-sensitive interferometric synthetic aperture microscopy

      Polarization-sensitive interferometric synthetic aperture microscopy
      Three-dimensional optical microscopy suffers from the well-known compromise between transverse resolution and depth-of-field. This is true for both structural imaging methods and their functional extensions. Interferometric synthetic aperture microscopy (ISAM) is a solution to the 3D coherent microscopy inverse problem that provides depth-independent transverse resolution. We demonstrate the extension of ISAM to polarization sensitive imaging, termed polarization-sensitive interferometric synthetic aperture microscopy (PS-ISAM). This technique is the first functionalization of the ...
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    8. Intraoperative Assessment of Final Margins with a Handheld Optical Imaging Probe During Breast-Conserving Surgery May Reduce the Reoperation Rate: Results of a Multicenter Stud

      Intraoperative Assessment of Final Margins with a Handheld Optical Imaging Probe During Breast-Conserving Surgery May Reduce the Reoperation Rate: Results of a Multicenter Stud
      Background A multicenter, prospective, blinded study was performed to test the feasibility of using a handheld optical imaging probe for the intraoperative assessment of final surgical margins during breast-conserving surgery (BCS) and to determine the potential impact on patient outcomes. Methods Forty-six patients with early-stage breast cancer (one with bilateral disease) undergoing BCS at two study sites, the Johns Hopkins Hospital and Anne Arundel Medical Center, were enrolled in this ...
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    9. Computational high-resolution optical imaging of the living human retina

      Computational high-resolution optical imaging of the living human retina
      High-resolution in vivo imaging is of great importance for the fields of biology and medicine. The introduction of hardware-based adaptive optics (HAO) has pushed the limits of optical imaging, enabling high-resolution near diffraction-limited imaging of previously unresolvable structures 1 , 2 . In ophthalmology, when combined with optical coherence tomography, HAO has enabled a detailed three-dimensional visualization of photoreceptor distributions 3 , 4 and individual nerve fibre bundles 5 in the living human ...
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    10. Computational adaptive optics for interferometric synthetic aperture microscopy and other interferometric imaging

      Computational adaptive optics for interferometric synthetic aperture microscopy and other interferometric imaging
      Methods for correcting for aberrations in the image or three-dimensional reconstruction of a sampled region obtained by broadband interferometry. The sampled region is illuminated with a broadband beam of light, and light returned from the sample is detected, along with a reference beam, in order to derive an interference signal for pixels of a volume spanned by wavenumber and axes transverse to the beam propagation direction. An optimization procedure is ...
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    11. Feature Of The Week 5/12/13: University of Illinois at Urbana-Champaign Reports on Real-Time In Vivo Computed Optical Interferometric Tomography

      Feature Of The Week 5/12/13: University of Illinois at Urbana-Champaign Reports on Real-Time In Vivo Computed Optical Interferometric Tomography
      Real-time, high-resolution tomography over an extended field-of-view in scattering tissues remains an elusive goal for biomedical imaging. The apparent trade-off between the depth-of-field and lateral resolution in optical imaging degrades the image resolution outside the confocal region in OCT. Although a number of approaches have been utilized to overcome these limitations, many of these techniques are plagued by either high computational complexity or complicated optical setups. ISAM is a computational ...
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  2. About P. Scott Carney

    P. Scott Carney

    Paul Scott Carney is an Associate Professor with the University of Illinois at Urbana Champaign and holds appointments with the Department of Electrical and Computer Engineering, the Beckman Institute for Advanced Science and Technology, and the Coordinated Science Laboratory.

  3. Quotes

    1. I’ve been doing a lot of work in OCT with Stephen Boppart and spectroscopy with Rohit Bhargava and outside collaborators to take this 140-year-old piece of physics, Maxwell’s equations, put a little bit of fancy mathematics around it, and make new predictions about the way the world works.
      In Simple Equations Power Scott Carney's Research