1. Ou Tan

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    1. Mentioned In 59 Articles

    2. Systems and methods of glaucoma diagnosis based on frequency analysis of inner retinal surface profile measured by optical coherence tomography

      Explore uspto.gov Ophthalmology , Patents
      Systems and methods of glaucoma diagnosis based on frequency analysis of inner retinal surface profile measured by optical coherence tomography
      A method for detecting glaucoma in a subject based on spatial frequency analysis of the inner limiting membrane (ILM) as obtained from optical coherence tomography (OCT) image data is disclosed. Based on the spatial frequency content of the analyzed ILM profile, a quantity called the Retinal surface contour variability (RSCV) is calculated and the presence or absence of a glaucoma condition is determined based on the RSCV magnitude.
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      Mentions: David Huang Oregon Health & Science University Ou Tan

    3. Nerve Fiber Flux Analysis Using Wide-Field Swept-Source Optical Coherence Tomography

      Explore TVST Journal Ophthalmology
      Nerve Fiber Flux Analysis Using Wide-Field Swept-Source Optical Coherence Tomography
      Purpose : To devise a method to quantify nerve fibers over their arcuate courses over an extended peripapillary area using optical coherence tomography (OCT). Methods : Participants were imaged with 8 8-mm volumetric OCT scans centered at the optic disc. A new quantity, nerve fiber flux (NFF), represents the cross-sectional area transected perpendicular to the nerve fibers. The peripapillary area was divided into 64 tracks with equal flux. An iterative algorithm traced ...
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      Mentions: David Huang Oregon Health & Science University Ou Tan

    4. Assessment Of Retinal Blood Flow In Diabetic Retinopathy Using Doppler FOURIER-DOMAIN Optical Coherence Tomography

      Explore LWW Online Ophthalmology
      Assessment Of Retinal Blood Flow In Diabetic Retinopathy Using Doppler FOURIER-DOMAIN Optical Coherence Tomography
      Purpose: To evaluate retinal blood flow measurements in normal eyes and eyes with varying levels of diabetic retinopathy (DR) using Doppler Fourier-domain optical coherence tomography (FD-OCT). Methods: Twenty-two eyes of 19 subjects, 10 with severe nonproliferative DR (NPDR) and 12 with proliferative DR (PDR), were compared with 44 eyes of 40 healthy control subjects. All eyes were scanned by RTvue FD-OCT. Color disk photographs and cube/volume scans of the ...
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      Mentions: David Huang Oregon Health & Science University Ou Tan

    5. Comparison of Glaucoma Progression Detection by Optical Coherence Tomography and Visual Field

      Explore American Journal of Ophthalmology Ophthalmology
      Comparison of Glaucoma Progression Detection by Optical Coherence Tomography and Visual Field
      Purpose To compare longitudinal glaucoma progression detection using optical coherence tomography (OCT) and visual field (VF). Design Validity assessment Method We analyzed subjects with more than 5 follow-up visits (every 6 months) in the multi-center Advanced Imaging for Glaucoma Study. Fourier-domain optical coherence tomography (OCT) was used to map the thickness of the peripapillary retinal nerve fiber layer (NFL) and ganglion cell complex (GCC). OCT-based progression detection was defined as ...
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      Mentions: David Huang Joel S. Schuman Oregon Health & Science University

    6. Optical coherence tomography angiography enhances the detection of optic nerve damage in multiple sclerosis

      Explore BJO Online Ophthalmology
      Optical coherence tomography angiography enhances the detection of optic nerve damage in multiple sclerosis
      Background Quantitative assessment of optic nerve damage is important in the evaluation of optic neuritis (ON) and multiple sclerosis (MS). Objective To detect optic nerve damage using optical coherence tomography (OCT) and OCT angiography in MS. Methods Peripapillary retinal nerve fibre layer (NFL) thickness, macular ganglion cell complex (GCC) thickness and Optic Nerve Head Flow Index (ONH-FI) were measured. The ONH-FI was defined as flow signal averaged over the optic ...
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      Mentions: David Huang Oregon Health & Science University Yali Jia

    7. Handheld OCT Angiography and Ultra–Wide-Field OCT in Retinopathy of Prematurity

      Explore The JAMA Network Ophthalmology
      Handheld OCT Angiography and Ultra–Wide-Field OCT in Retinopathy of Prematurity
      Importance Retinopathy of prematurity (ROP) is a leading cause of childhood blindness worldwide. Optical coherence tomography (OCT) has improved the care of adults with vitreoretinal disease, and OCT angiography (OCTA) is demonstrating promise as a technique to visualize the retinal vasculature with lower risk and cost than fluorescein angiography. However, to date, there are no commercially available devices able to obtain ultrawide-field OCT or OCTA images in neonates. Objective To ...
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      Mentions: David Huang Oregon Health & Science University Ou Tan

    8. Methods and systems to measure corneal epithelial thickness and power, stromal thickness, subepithelial corneal power and topography for disease diagnosis

      Explore uspto.gov Ophthalmology , Patents
      Methods and systems to measure corneal epithelial thickness and power, stromal thickness, subepithelial corneal power and topography for disease diagnosis
      This invention discloses methods and systems for measuring corneal epithelial thickness and power, stromal thickness, subepitheila corneal power and topography. The systems and methods disclosed herein are non-invasive, non-contact and automated imaging methods which preferably makes use of Fourier-domain optical tomography. Also disclosed herein are scanning patterns and image analysis methods for utilizing and analyzing Fourier-domain optical coherence tomography images to obtain information about conical epithelial and stromal properties as ...
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      Mentions: David Huang University of Southern California Ou Tan

    9. Retinal Blood Flow Response to Hyperoxia Measured With En Face Doppler Optical Coherence Tomography

      Explore IOVS Journal Ophthalmology
      Retinal Blood Flow Response to Hyperoxia Measured With En Face Doppler Optical Coherence Tomography
      Purpose : To use multiplane en face Doppler optical coherence tomography (OCT) to measure the change in total retinal blood flow (TRBF) in response to hyperoxia. Methods : One eye of each healthy human participant ( n = 8) was scanned with a commercial high-speed (70-kHz) spectral OCT system. Three repeated scans were captured at baseline and after 10 minutes of oxygen (hyperoxia) by open nasal mask. The procedure was performed twice on day ...
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      Mentions: David Huang Oregon Health & Science University Yali Jia

    10. Glaucoma Increases Retinal Surface Contour Variability as Measured by Optical Coherence Tomography

      Explore IOVS Journal Ophthalmology
      Glaucoma Increases Retinal Surface Contour Variability as Measured by Optical Coherence Tomography
      Purpose : We investigated the feasibility of glaucoma detection by measuring retinal surface contour variability (RSCV) using optical coherence tomography (OCT). Methods : The peripapillary region in one eye of each participant was scanned over an 8 8 mm area with a swept source OCT prototype. The retinal surface contour was sampled at approximately 1.5- to 3.5-mm radius circles centered on the optic nerve head. The RSCV is defined as ...
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      Mentions: David Huang Oregon Health & Science University Ou Tan

    12. Subclinical keratoconus detection by pattern analysis of corneal and epithelial thickness maps with optical coherence tomography

      Explore ScienceDirect Ophthalmology
      Subclinical keratoconus detection by pattern analysis of corneal and epithelial thickness maps with optical coherence tomography
      Purpose To screen for subclinical keratoconus by analyzing corneal, epithelial, and stromal thickness map patterns with Fourier-domain optical coherence tomography (OCT). Setting Four centers in the United States. Design Cross-sectional observational study. Methods Eyes of normal subjects, subclinical keratoconus eyes, and the topographically normal eye of a unilateral keratoconus patient were studied. Corneas were scanned using a 26000 Hz Fourier-domain OCT system (RTVue). Normal subjects were divided into training and ...
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      Mentions: David Huang Oregon Health & Science University Ou Tan

    13. Longitudinal and Cross-Sectional Analyses of Age and Intraocular Pressure Effects on Retinal Nerve Fiber Layer and Ganglion Cell Complex Thickness

      Explore IOVS Journal Ophthalmology
      Longitudinal and Cross-Sectional Analyses of Age and Intraocular Pressure Effects on Retinal Nerve Fiber Layer and Ganglion Cell Complex Thickness
      Purpose : To study the effect of age and intraocular pressure (IOP) on retinal nerve fiber layer (NFL) and ganglion cell complex (GCC) thickness in normal eyes. Methods : We analyzed the data from subjects enrolled in the multi-center longitudinal Advanced Imaging for Glaucoma (AIG) Study (www.AIGStudy.net). The data included yearly visits from the normal subjects group in the AIGS study. Fourier-domain optical coherence tomography (OCT) was used to map ...
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      Mentions: University of Pittsburgh David Huang Joel S. Schuman

    14. Regression Analysis of Optical Coherence Tomography Disc Variables for Glaucoma Diagnosis

      Explore LWW Online Ophthalmology
      Regression Analysis of Optical Coherence Tomography Disc Variables for Glaucoma Diagnosis
      Purpose: To report diagnostic accuracy of optical coherence tomography (OCT) disc variables using both time-domain (TD) and Fourier-domain (FD) OCT, and to improve the use of OCT disc variable measurements for glaucoma diagnosis through regression analyses that adjust for optic disc size and axial length-based magnification error. Design: Observational, cross-sectional. Participants: In total, 180 normal eyes of 112 participants and 180 eyes of 138 participants with perimetric glaucoma from the ...
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      Mentions: University of Pittsburgh David Huang Joel S. Schuman

    15. Predicting Development of Glaucomatous Visual Field Conversion Using Baseline Fourier-Domain Optical Coherence Tomography

      Explore American Journal of Ophthalmology Ophthalmology
      Predicting Development of Glaucomatous Visual Field Conversion Using Baseline Fourier-Domain Optical Coherence Tomography
      Purpose To predict the development of glaucomatous visual field (VF) defects using Fourier-domain optical coherence tomography (FD-OCT) measurements at baseline visit. Design Multi-center longitudinal observational study. Glaucoma suspects and pre-perimetric glaucoma participants in the Advanced Imaging for Glaucoma Study. Methods The optic disc, the peripapillary retinal nerve fiber layer (NFL), and macular ganglion cell complex (GCC) were imaged with FD-OCT VF was assessed every 6 months. Conversion to perimetric glaucoma ...
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      Mentions: University of Pittsburgh David Huang Joel S. Schuman

    16. OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY OF TIME COURSE OF CHOROIDAL NEOVASCULARIZATION IN RESPONSE TO ANTI-ANGIOGENIC TREATMENT

      Explore LWW Online Ophthalmology
      OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY OF TIME COURSE OF CHOROIDAL NEOVASCULARIZATION IN RESPONSE TO ANTI-ANGIOGENIC TREATMENT
      Purpose: To use optical coherence tomography (OCT) angiography to monitor the short-term blood flow changes in choroidal neovascularization (CNV) in response to treatment. Methods: In this retrospective report, a case of exudative CNV was followed closely with OCT angiography over three cycles of antiangiogenic treatment. Outer retinal flow index, CNV flow area and central macular retinal thickness were measured. Results: Quantitative measurements of CNV flow area and flow index showed ...
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      Mentions: David Huang Oregon Health & Science University Yali Jia
    17. 1-15 of 59 1 2 3 4 »
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  4. About Ou Tan

    Ou Tan

    Ou Tan, PhD, is an Assistant Professor of Research Ophthalmology at the Keck School of Medicine of the University of Southern California. He joined the faculty at Doheny Eye Institute in September 2004. Dr. Tan earned his PhD in Biomedical Engineering from Zhejiang University, Hangzhou, China, in 2000. He completed his post-doctoral research at National Institute of Radiology Science, Chiba, Japan, in 2002. He acted as a research associate in Cleveland Clinic Foundation from 2002 to 2004. His research of interest includes medical image analysis and computer aided diagnosis in glaucoma, diabetic retinopathy, and age related macular degeneration with optical coherence tomography.

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