1. Osaka University

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    1. Mentioned In 118 Articles

    2. Transcutaneous immunization using microneedles and cubosomes: Mechanistic investigations using Optical Coherence Tomography and Two-Photon Microscopy

      Transcutaneous immunization using microneedles and cubosomes: Mechanistic investigations using Optical Coherence Tomography and Two-Photon Microscopy
      ...Cardiff University, United Kingdom * ^c Laboratory of Cellular Dynamics, Immunology Frontier Research Center, Osaka University * ^d Department of Physics, University of Otago, New Zealand * ^e Pharmaceutical Design and D...
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    3. Three-dimensional high-speed optical coherence tomography system using KTN swept light source

      Three-dimensional high-speed optical coherence tomography system using KTN swept light source
      Three-dimensional (3D) optical coherence tomography (3D-OCT) has attracted attention for visualising complex structures in the biomedical field. In this reported work, a high-speed 3D-OCT system is developed, which is based on a high-speed swept light source and aMach-Zehnder interferometer with a high-speed photodetector. The light source, incorporating a KTa 1-x Nb x O 3 electro-optic deflector, operates at a repetition rate of 200 kHz and enables high-speed data acquisition. As ...
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    4. High-Speed Optical Coherence Tomography System Using a 200-kHz Swept Light Source with a KTN Deflector

      High-Speed Optical Coherence Tomography System Using a 200-kHz Swept Light Source with a KTN Deflector
      We demonstrate a high-speed swept-source optical coherence tomography (SS-OCT) system, which is based on a high- speed swept light source and a Mach-Zehnder interferometer with a high-speed photodetector. The light source is an external-cavity laser tuned by a KTN electro-optic deflector, which exhibits a very fast response and large deflection. The scanning wavelength range is almost 80 nm up to 200 kHz with a 400-V deflector driving voltage. The system ...
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    5. 3-D Choroidal Thickness Maps from EDI-OCT in Highly Myopic Eyes

      3-D Choroidal Thickness Maps from EDI-OCT in Highly Myopic Eyes
      Purpose: Myopic chorioretinal atrophy is a debilitating condition that causes severe loss of primary vision. However, its mechanisms and pathologic course are not well understood. We performed volumetric measurements of the posterior choroid via three-dimensional analysis of the choroid in patients with high myopia to understand its structure, and we compared the measurements with those of normal subjects. Methods: Twenty-five highly myopic but otherwise normal eyes and 25 nonmyopic eyes ...
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    6. Dynamic imaging of a small artery underneath skin surface of a human finger by optical coherence tomography

      Dynamic imaging of a small artery underneath skin surface of a human finger by optical coherence tomography
      OCT is a powerful tool for detection of physiological functions of micro organs underneath the human skin surface, besides the clinical application to ophthalmology, as recently demonstrated by the authors group. In particular, dynamics of peripheral vessels can be observed clearly in the time-sequential OCT images. Among the vascular system, only the small artery has two physiological functions both for the elastic artery and for muscle-controlled one. It, therefore, is ...
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      Mentions: Osaka University
    7. Cardiac Allograft Vasculopathy Progression Associated With Intraplaque Neovascularization

      Cardiac Allograft Vasculopathy Progression Associated With Intraplaque Neovascularization
      A 52-year-old man underwent scheduled cardiac catheterization for assessment of cardiac allograft vasculopathy (CAV) at 3 and 12 months after heart transplantation (HTx). Intravascular ultrasound showed only mild CAV in the left anterior descending coronary artery (LAD) at 3 months ( B , Online Video 1 ). However, at 12 months, CAV progression was detected, predominantly in the proximal LAD ( A and C3 , Online Video 2 ). Corresponding optical coherence tomography images revealed the ...
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    8. Optical Coherence Tomography in IgG4-related Coronary Periarteritis

      Optical Coherence Tomography in IgG4-related Coronary Periarteritis
      We herein report the case of a 66-year-old patient with acute coronary syndrome who was diagnosed with immunoglobulin G4 (IgG4)-related coronary periarteritis with a perivascular pseudotumor and underwent coronary bypass graft surgery (1). The serum IgG4 concentration markedly decreased after the bypass was performed and gradually returned to the baseline level one-year after surgery (2). Despite initially achieving success, the bypass graft to the left circumflex artery (Lcx) was ...
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    9. Detailed observation of arterial healing after stent implantation in swine arteries by using optical coherence tomography

      Detailed observation of arterial healing after stent implantation in swine arteries by using optical coherence tomography
      BACKGROUND: Histopathological examination is not suitable for sequential in vivo analysis of arterial healing after stenting because it can be performed only after the animals are killed. Optical coherence tomography (OCT) provides higher resolution than intravascular ultrasound (IVUS). The aim of this study was to compare arterial healing images after stenting on the basis of the findings of histopathological examination, IVUS, and OCT. METHODS: We examined 12 vessels; 12 bare-metal ...
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    10. Feature Of The Week 4/8/12: Researchers at Osaka and Nagoya University Investigate The Use of Ultrahigh Resolution OCT for Imaging Protein Crystals

      Feature Of The Week 4/8/12: Researchers at Osaka and Nagoya University Investigate The Use of Ultrahigh Resolution OCT for Imaging Protein Crystals
      technique used for atomic-resolution protein-structure studies, and currently, robotic automation is often used to monitor and optimize crystallization conditions. However, it is often difficult to identify, by conventional light microscopy, crystals that can be used for X-ray crystallography when micro-size, needle, and salt crystals are also present in the crystallization medium.For the work reported herein, we demonstrated that micro-scale, non-invasive, three-dimensional (3D) cross-sectional, μm-resolution imaging of protein crystals could ...
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    11. 61-75 of 118 « 1 2 3 4 5 6 7 8 »
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  2. About Osaka University

    Osaka University

    Osaka University is a major national university located in Osaka, Japan. It is the sixth oldest university in Japan as the Osaka Prefectural Medical College, and formerly one of the Imperial Universities of Japan. Numerous prominent scientists worked at the Osaka University such as the Nobel Laureate in Physics Hideki Yukawa.  Also see Osaka University Medical School.  We aim to develop the research capability of our researchers and offer them comprehensive medical knowledge so that they can engage in research activities independently. We strive to foster extensively knowledgeable health care specialists with a flexible and methodical mind. We aim to train scientists and doctors who can meet present health care needs in the specialized field of nursing, as well as embrace the development of science. In addition, we endeavor to nurture scientists who are able to provide 21st Century intellectual leadership in the fields of Nursing and Medical Technology and Science.