1. Osaka University

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    1. Mentioned In 93 Articles

    2. Retinal Microvasculature and Visual Acuity in Eyes With Branch Retinal Vein Occlusion: Imaging Analysis by Optical Coherence Tomography Angiography

      Retinal Microvasculature and Visual Acuity in Eyes With Branch Retinal Vein Occlusion: Imaging Analysis by Optical Coherence Tomography Angiography
      Purpose : To investigate microvascular changes in the superficial capillary plexus (SCP) and deep capillary plexus (DCP) in eyes with resolved branch retinal vein occlusion (BRVO) and their association with best-corrected visual acuity (BCVA). Methods : Eighty-five eyes (82 consecutive patients) with BRVO after resolution of the macular edema were retrospectively evaluated. All patients underwent optical coherence tomography angiography (OCTA) for assessment of microvascular changes, including capillary telangiectasia, microaneurysm, and disruption of ...
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    3. High frame-rate en face optical coherence tomography system using KTN optical beam deflector

      High frame-rate en face optical coherence tomography system using KTN optical beam deflector
      We developed high frame-rate en face optical coherence tomography (OCT) system using KTa 1-x Nb x O 3 (KTN) optical beam deflector. In the imaging system, the fast scanning was performed at 200 kHz by the KTN optical beam deflector, while the slow scanning was performed at 800 Hz by the galvanometer mirror. As a preliminary experiment, we succeeded in obtaining en face OCT images of human fingerprint with a ...
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    4. Application to skin physiology using optical coherence tomography

      Application to skin physiology using optical coherence tomography
      Background and aims: The sweat glands and peripheral vessels beneath the skin surface act as minute organs governed by the skin sympathetic nerves and have important physiological functions for body temperature control and nutrition support along with maintenance of a peripheral organization. Dynamics of the mental sweating of sweat glands and the peripheral vessels reflect the activity of a sympathetic nerve. The purpose of this paper is to study the ...
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      Mentions: Osaka University
    5. Quantitative Evaluation of the Natural Progression of Keratoconus Using Three-Dimensional Optical Coherence Tomography

      Quantitative Evaluation of the Natural Progression of Keratoconus Using Three-Dimensional Optical Coherence Tomography
      Purpose : We quantified the chronologic progression of keratoconus using anterior segment optical coherence tomography (AS-OCT). Methods : A total of 217 eyes from 113 patients with keratoconus, keratoconus suspect, or forme fruste keratoconus were evaluated by corneal tomography using swept-source OCT. Age-dependent changes in the radius of the posterior best-fit sphere (R post ), minimum corneal thickness (T min ), and distance from the thinnest point to the corneal vertex (D min ) were ...
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      Mentions: Osaka University
    6. Quantitative polarization and flow evaluation of choroid and sclera by multifunctional Jones matrix optical coherence tomography

      Quantitative polarization and flow evaluation of choroid and sclera by multifunctional Jones matrix optical coherence tomography
      Quantitative evaluation of optical properties of choroid and sclera are performed by multifunctional optical coherence tomography. Five normal eyes, five glaucoma eyes and one choroidal atrophy eye are examined. The refractive error was found to be correlated with choroidal birefringence, polarization uniformity, and flow in addition to scleral birefringence among normal eyes. The significant differences were observed between the normal and the glaucoma eyes, as for choroidal polarization uniformity, flow ...
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    7. Functional optical coherence tomography of rat olfactory bulb with periodic odor stimulation

      Functional optical coherence tomography of rat olfactory bulb with periodic odor stimulation
      In rodent olfactory bulb (OB), optical intrinsic signal imaging (OISI) is commonly used to investigate functional maps to odorant stimulations. However, in such studies, the spatial resolution in depth direction (z-axis) is lost because of the integration of light from different depths. To solve this problem, we propose functional optical coherence tomography (fOCT) with periodic stimulation and continuous recording. In fOCT experiments of in vivo rat OB, propionic acid and ...
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    8. Real-time quantitation of internal metabolic activity of three-dimensional engineered tissues using an oxygen microelectrode and optical coherence tomography

      Real-time quantitation of internal metabolic activity of three-dimensional engineered tissues using an oxygen microelectrode and optical coherence tomography
      Recent progress in tissue engineering technology has enabled us to develop thick tissue constructs that can then be transplanted in regenerative therapies. In clinical situations, it is vital that the engineered tissues to be implanted are safe and functional before use. However, there is currently a limited number of studies on real-time quality evaluation of thick living tissue constructs. Here we developed a system for quantifying the internal activities of ...
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      Mentions: Osaka University
    9. Analysis of Peripapillary Geometric Characters in High Myopia Using Swept-Source Optical Coherence Tomography

      Analysis of Peripapillary Geometric Characters in High Myopia Using Swept-Source Optical Coherence Tomography
      Purpose : We measured the three-dimensional geometric profile around the optic nerve head (ONH) using swept-source optical coherence tomography (SS-OCT) in highly myopic eyes. Methods : We studied 114 highly myopic eyes (6.0 diopters [D]) of 114 patients without glaucoma. Eyes were examined using the prototype SS-OCT. The retinal pigment epithelium (RPE) and chorioscleral interface were traced, and the mean y -axis coordinates of 24 sectors were calculated in circular peripapillary ...
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    10. Plasma Pentraxin3 Level Is Associated With Plaque Vulnerability Assessed by Optical Coherence Tomography in Patients With Coronary Artery Disease

      Plasma Pentraxin3 Level Is Associated With Plaque Vulnerability Assessed by Optical Coherence Tomography in Patients With Coronary Artery Disease
      The role of pentraxin 3 (PTX3) has been implicated in the process of plaque vulnerability. However, few studies have addressed the direct relationship between plaque morphology and plasma PTX3. We evaluated the relationship between coronary vulnerable plaque, assessed by optical coherence tomography (OCT), and plasma PTX3 in patients with coronary artery disease (CAD). OCT was used to determine plaque vulnerability in 51 patients with non-ST segment elevation acute coronary syndrome ...
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    11. 0.54 μm resolution two-photon interference with dispersion cancellation for quantum optical coherence tomography

      0.54 μm resolution two-photon interference with dispersion cancellation for quantum optical coherence tomography
      Quantum information technologies harness the intrinsic nature of quantum theory to beat the limitations of the classical methods for information processing and communication. Recently, the application of quantum features to metrology has attracted much attention. Quantum optical coherence tomography (QOCT), which utilizes two-photon interference between entangled photon pairs, is a promising approach to overcome the problem with optical coherence tomography (OCT): As the resolution of OCT becomes higher, degradation of ...
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    12. Birefringence imaging of posterior eye by multi-functional Jones matrix optical coherence tomography

      Birefringence imaging of posterior eye by multi-functional Jones matrix optical coherence tomography
      A clinical grade prototype of posterior multifunctional Jones matrix optical coherence tomography (JM-OCT) is presented. This JM-OCT visualized depth-localized birefringence in addition to conventional cumulative phase retardation imaging through local Jones matrix analysis. In addition, it simultaneously provides a sensitivity enhanced scattering OCT, a quantitative polarization uniformity contrast, and OCT-based angiography. The probe beam is at 1- m wavelength band. The measurement speed and the depth-resolution were 100,000 A-lines ...
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    13. Nondestructive observation of teeth post core-space using optical coherence tomography: comparison with microcomputed tomography and live images

      Nondestructive observation of teeth post core-space using optical coherence tomography: comparison with microcomputed tomography and live images
      No previous reports have observed inside the root canal using both optical coherence tomography (OCT) and x-ray microcomputed tomography ( CT ) for the same sample. The purpose of this study was to clarify both OCT and CT image properties from observations of the same root canal after resin core build-up treatment. As OCT allows real-time observation of samples, gap formation may be able to be shown in real time. A dual-cure ...
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      Mentions: Osaka University
    14. Localization of Coronary High-Intensity Signals on T1-Weighted MR Imaging : Relation to Plaque Morphology and Clinical Severity of Angina Pectoris

      Localization of Coronary High-Intensity Signals on T1-Weighted MR Imaging : Relation to Plaque Morphology and Clinical Severity of Angina Pectoris
      Objectives This study sought to investigate the relationship between localization of high-intensity signals (HISs) on T1-weighted imaging (T1WI) with the noncontrast magnetic resonance technique and plaque morphology detected on optical coherence tomography, and the clinical severity of angina pectoris. Background Since the introduction of the T1WI noncontrast magnetic resonance technique for plaque imaging, some groups have reported that HISs in the coronary artery on T1WI are associated with a vulnerable ...
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      Mentions: Osaka University
    15. Optical coherence tomography and intravascular ultrasound evaluation of cardiac allograft vasculopathy with and without intimal neovascularization

      Optical coherence tomography and intravascular ultrasound evaluation of cardiac allograft vasculopathy with and without intimal neovascularization
      Aims Neovascularization is closely associated with plaque progression in non-heart transplantation subjects; on the other hand, cardiac allograft vasculopathy causes unfavourable outcomes. Intravascular ultrasound (IVUS) and optical coherence tomography (OCT) can provide microscopic assessment in vivo . The aim of this study was to investigate the impact of neovascularization on intimal proliferation. Methods and results Both IVUS and OCT were attempted in 45 consecutive patients during annual catheterization after heart transplantation ...
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    16. Retinal nerve fiber layer and ganglion cell complex thicknesses measured with spectral-domain optical coherence tomography in eyes with no light perception due to nonglaucomatous optic neuropathy

      Retinal nerve fiber layer and ganglion cell complex thicknesses measured with spectral-domain optical coherence tomography in eyes with no light perception due to nonglaucomatous optic neuropathy
      PURPOSE: To measure retinal nerve fiber layer thickness (RNFLT) and ganglion cell complex thickness (GCCT) in eyes with no light perception due to nonglaucomatous optic neuropathy using spectral-domain optical coherence tomography. METHODS: Fourteen eyes of 14 patients (9 women, 5 men; mean age 56.0 16.6 (standard deviation) years] with no light perception due to optic neuropathy were recruited to this retrospective study. Only clinically stable eyes were included ...
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      Mentions: Osaka University
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  2. About Osaka University

    Osaka University

    Osaka University is a major national university located in Osaka, Japan. It is the sixth oldest university in Japan as the Osaka Prefectural Medical College, and formerly one of the Imperial Universities of Japan. Numerous prominent scientists worked at the Osaka University such as the Nobel Laureate in Physics Hideki Yukawa.  Also see Osaka University Medical School.  We aim to develop the research capability of our researchers and offer them comprehensive medical knowledge so that they can engage in research activities independently. We strive to foster extensively knowledgeable health care specialists with a flexible and methodical mind. We aim to train scientists and doctors who can meet present health care needs in the specialized field of nursing, as well as embrace the development of science. In addition, we endeavor to nurture scientists who are able to provide 21st Century intellectual leadership in the fields of Nursing and Medical Technology and Science.