1. Osaka University

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    1. Mentioned In 132 Articles

    2. Predicting 10-2 Visual Field From Optical Coherence Tomography in Glaucoma Using Deep Learning Corrected With 24-2/30-2 Visual Field

      Predicting 10-2 Visual Field From Optical Coherence Tomography in Glaucoma Using Deep Learning Corrected With 24-2/30-2 Visual Field
      Purpose: To investigate whether a correction based on a Humphrey field analyzer (HFA) 24-2/30-2 visual field (VF) can improve the prediction performance of a deep learning model to predict the HFA 10-2 VF test from macular optical coherence tomography (OCT) measurements. Methods: This is a multicenter, cross-sectional study. The training dataset comprised 493 eyes of 285 subjects (407, open-angle glaucoma [OAG]; 86, normative) who underwent HFA 10-2 testing and ...
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    3. Effects of Number of Stent Connectors on Mid-Term Vessel Healing and Stent Expansion Assessed by Optical Coherence Tomography

      Effects of Number of Stent Connectors on Mid-Term Vessel  Healing and Stent Expansion Assessed by Optical   Coherence Tomography
      Objective: Coronary stents generally consist of hoops and connectors. The number of connectors has been associated with longitudinal strength, flexibility, and deliverability of stents. However, a mid-term impact of number of connectors after stent implantation has been unclear. We sought to examine the effect of number of connectors on vessel healing and stent expansion using optical coherence tomogra - phy (OCT). Materials and Methods: The study included 39 patients with 46 ...
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      Mentions: Osaka University
    4. Association of disorganization of retinal inner layers with optical coherence tomography angiography features in branch retinal vein occlusion

      Association of disorganization of retinal inner layers with optical coherence tomography angiography features in branch retinal vein occlusion
      Purpose: To examine the associations between the disorganization of the retinal inner layers (DRIL) and optical coherence tomography angiography characteristics and visual acuity (VA) outcomes in eyes with macular edema secondary to branch retinal vein occlusion (BRVO). Methods: In this single-center cross-sectional cohort study, the data of 43 patients with macular edema secondary to BRVO that received pro re nata anti-vascular endothelial growth factor therapy were analyzed. B-scan and en ...
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      Mentions: Osaka University
    5. Flow pattern and perforating vessels in three different phases of myopic choroidal neovascularization seen by swept-source optical coherence tomography angiography

      Flow pattern and perforating vessels in three different phases of myopic choroidal neovascularization seen by swept-source optical coherence tomography angiography
      Purpose To compare the choroidal neovascularization (CNV) flow patterns and the relationship between perforating vessels (PVs) and CNV in the three different stages of networks in myopic CNV (mCNV) using swept-source optical coherence tomography angiography (SS-OCTA). Methods This retrospective study included 28 eyes with mCNV that was divided into three phases (active, scar, and atrophic) and observed by SS-OCTA. SS-OCTA findings, with special focus on the relationship between the PVs ...
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      Mentions: Osaka University
    6. Comparable neointimal healing in patients with stable coronary lesions and acute coronary syndrome: 3-month optical coherence tomography analysis

      Comparable neointimal healing in patients with stable coronary lesions and acute coronary syndrome: 3-month optical coherence tomography analysis
      We aimed to assess a possible difference of the neointimal coverage status and its quality after implantation of the current-generation metallic stents in patients with acute coronary syndrome (ACS) vs. stable coronary lesions (non-ACS). We comprehensively analyzed three prospective single-center observational studies RESTORE (UMIN000033009), HEAL-BioFreedom (UMIN000029692), and HEAL-BioFreedom ACS (UMIN000034769). All patients who received successful optical coherence tomography (OCT) examination at planned 3-month follow-up after stent implantation were analyzed. Study ...
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    7. New severity grading system for Fuchs endothelial corneal dystrophy using anterior segment optical coherence tomography

      New severity grading system for Fuchs endothelial corneal dystrophy using anterior segment optical coherence tomography
      Purpose: To report a new severity grading system for Fuchs endothelial corneal dystrophy (FECD) using anterior segment optical coherence tomography (AS-OCT). Methods: This observational case series included 75 eyes of 43 patients with FECD and 33 eyes of 33 healthy subjects. Pachymetry and posterior elevation maps were used to determine the AS-OCT-based grading scores. FECD severity was graded from 0-3 as follows: 0, normal; 1, guttae only; 2, stromal oedema ...
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      Mentions: Osaka University
    8. Analysis of sweating by optical coherence tomography in patients with palmoplantar hyperhidrosis

      Analysis of sweating by optical coherence tomography in patients with palmoplantar hyperhidrosis
      Optical coherence tomography (OCT) is a high-resolution tomographic imaging technique that uses optical interference. OCT has enabled the non-invasive three-dimensional analysis of individual acrosyringia in the stratum corneum in human skin. However, no report on the measurement of sweating by OCT using clinical data from humans has been published to date. Twenty patients with hyperhidrosis and twenty healthy subjects were included in this study. Imaging of acrosyringia in the stratum ...
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    9. Difference of vascular healing between bioabsorbable-polymer and durable-polymer new generation drug-eluting stents: an optical coherence tomographic analysis

      Difference of vascular healing between bioabsorbable-polymer and durable-polymer new generation drug-eluting stents: an optical coherence tomographic analysis
      The comparison of bioabsorbable-polymer and durable-polymer stents has continued to be debated, and there is ongoing concern regarding vascular healing and late stent thrombosis. This study compared the vascular healing at 8-month follow-up by optical coherence tomography (OCT) between 4 different kinds of new generation drug-eluting stents (DESs). We enrolled 112 patients (112 de novo lesions) who underwent OCT guided percutaneous coronary intervention with 4 kinds of new generation DESs ...
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    10. Clinical impact of a new optical coherence tomography-derived volumetric method for evaluating stent expansion

      Clinical impact of a new optical coherence tomography-derived volumetric method for evaluating stent expansion
      The aim of this study was to investigate the impact of a new optical coherence tomography (OCT)-derived volumetric method for stent expansion (new-OCT method) to predict the target lesion revascularization (TLR) and compare the expansion findings between this new method and the conventional method because, in the real world, there are few clinical data on the new-OCT-method for stent expansion. One hundred forty lesions in 135 patients who underwent ...
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      Mentions: Osaka University
    11. Comparison of ocular surface squamous neoplasia and pterygium using anterior segment optical coherence tomography angiography

      Comparison of ocular surface squamous neoplasia and pterygium using anterior segment optical coherence tomography angiography
      Purpose To compare ocular surface squamous neoplasia (OSSN) and pterygium using anterior segment optical coherence tomography angiography (AS-OCTA). Observations Flow patterns of conjunctival vessels in patients with OSSN and pterygium were investigated using AS-OCTA. In case 1, slit-lamp examination of a 72-year-old woman revealed an elevated lesion with increased permeability of fluorescein in the inferior nasal conjunctiva of her left eye. AS-OCTA showed markedly meandering large blood vessels in both ...
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      Mentions: Osaka University
    12. Impact of asteroid hyalosis on internal higher-order aberrations in eyes with cataract accompanied by acoustic shadows on swept-source optical coherence tomography examination

      Impact of asteroid hyalosis on internal higher-order aberrations in eyes with cataract accompanied by acoustic shadows on swept-source optical coherence tomography examination
      Increased internal higher-order aberrations (HOAs) have been reported in eyes with asteroid hyalosis, which is usually asymptomatic. This report describes two patients with cataract and concurrent asteroid hyalosis. In the first case, internal HOAs were within the normal range and swept-source optical coherence tomography (SS-OCT) did not show acoustic shadows. After cataract surgery, visual acuity improved and internal HOAs remained within normal limits. However, in the second case, SS-OCT revealed ...
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      Mentions: Osaka University
    13. Anterior segment optical coherence tomography and in vivo confocal microscopy in cases of mucopolysaccharidosis

      Anterior segment optical coherence tomography and in vivo confocal microscopy in cases of mucopolysaccharidosis
      Purpose To report anterior segment evaluation in patients with mucopolysaccharidosis 1 using anterior segment optical coherence tomography and in vivo confocal microscopy. Observations Case 1 involved a 26-year-old man with mucopolysaccharidosis 1 HurlerScheie syndrome who presented with a corrected distance visual acuity of 20/67 in the right eye and 20/50 in the left eye because of bilateral corneal opacification. He had undergone bone marrow transplantation at the age ...
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      Mentions: Osaka University
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  2. About Osaka University

    Osaka University

    Osaka University is a major national university located in Osaka, Japan. It is the sixth oldest university in Japan as the Osaka Prefectural Medical College, and formerly one of the Imperial Universities of Japan. Numerous prominent scientists worked at the Osaka University such as the Nobel Laureate in Physics Hideki Yukawa.  Also see Osaka University Medical School.  We aim to develop the research capability of our researchers and offer them comprehensive medical knowledge so that they can engage in research activities independently. We strive to foster extensively knowledgeable health care specialists with a flexible and methodical mind. We aim to train scientists and doctors who can meet present health care needs in the specialized field of nursing, as well as embrace the development of science. In addition, we endeavor to nurture scientists who are able to provide 21st Century intellectual leadership in the fields of Nursing and Medical Technology and Science.