1. Osaka University

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    1. Mentioned In 106 Articles

    2. Parallel detection of Jones-matrix elements in polarization-sensitive optical coherence tomography

      Parallel detection of Jones-matrix elements in polarization-sensitive optical coherence tomography
      The polarization properties of a sample can be characterized using a Jones matrix. To measure the Jones matrix without assumptions of the sample, two different incident states of polarization are usually used. This requirement often causes certain drawbacks in polarization-sensitive optical coherence tomography (PS-OCT), e.g., a decrease in the effective A-scan rate or axial depth range, if a multiplexing scheme is used. Because both the A-scan rate and axial ...
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    3. Serial optical coherence tomography and angioscopic assessments of 10-year in-stent restenosis of Cypher sirolimus-eluting stent treated with drug-coated balloon angioplasty

      Serial optical coherence tomography and angioscopic assessments of 10-year in-stent restenosis of Cypher sirolimus-eluting stent treated with drug-coated balloon angioplasty
      The drug-coated balloon (DCB) angioplasty is considered a standard therapeutic option for in-stent restenosis. In the present case, we observed high-intensity spots on optical coherence tomography (OCT) and bright spots on coronary angioplasty (CAS) immediately after DCB angioplasty. The superficial high-intensity area on OCT presumably corresponded with the bright spots on CAS. The high-intensity superficial regions were thought to represent an iopromide/paclitaxel mixture. The present serial observation demonstrated that ...
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      Mentions: Osaka University
    4. Retinal Microvasculature and Visual Acuity after Intravitreal Aflibercept in Diabetic Macular Edema: An Optical Coherence Tomography Angiography Study

      Retinal Microvasculature and Visual Acuity after Intravitreal Aflibercept in Diabetic Macular Edema: An Optical Coherence Tomography Angiography Study
      We investigated changes in retinal vascular area and the foveal avascular zone (FAZ) after intravitreal aflibercept in diabetic macular edema (DME) and the association of these changes with visual outcomes. The retinal vascular area in the superficial capillary plexus (SCP) and the deep capillary plexus (DCP) and the FAZ area were measured using optical coherence tomography angiography (OCTA) in 23 eyes of 23 patients with DME, before and after intravitreal ...
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      Mentions: Osaka University
    5. Different Neoatherosclerosis Patterns in Drug-Eluting- and Bare-Metal Stent Restenosis ― Optical Coherence Tomography Study ―

      Different Neoatherosclerosis Patterns in Drug-Eluting- and Bare-Metal Stent Restenosis ― Optical Coherence Tomography Study ―
      Abstract Background: There are few reports about the differences between drug-eluting stents (DES) and bare metal stents (BMS) in neoatherosclerosis associated with in-stent restenosis (ISR), so we compared the frequency and characteristics of neoatherosclerosis with ISR evaluated by optical coherence tomography (OCT) in the present study. Methods and Results: Between March 2009 and November 2016, 98 consecutive patients with ISR who underwent diagnostic OCT were enrolled: 34 patients had a ...
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      Mentions: Osaka University
    6. En face optical coherence tomography imaging of beta and gamma parapapillary atrophy in high myopia

      En face optical coherence tomography imaging of beta and gamma parapapillary atrophy in high myopia
      Objective Recent studies have suggested that optical coherence tomography (OCT)-based classification of parapapillary atrophy (PPA) may be helpful in distinguishing glaucomatous from myopic optic disc changes. However, the pathological implications of PPA may be different in highly myopic eyes that exhibit optic disc deformations distinct from low to moderate myopia. Therefore, we conducted the current study to investigate factors associated with OCT-defined PPA zones measured in en face reconstructed ...
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    7. In vivo Micro-Tomographic Visualization of Capillary Angio-Dynamics Around Upper Dermis Under Mechanical Stimulus Using Low Coherence Interferometer “Optical Coherence Doppler Velocigraphy”

      In vivo Micro-Tomographic Visualization of Capillary Angio-Dynamics Around Upper Dermis Under Mechanical Stimulus Using Low Coherence Interferometer “Optical Coherence Doppler Velocigraphy”
      The skin aging process, e.g. wrinkles and sagging, caused by not only aging but also ultraviolet irradiation, could be related to the depression of metabolic function. Therefore, an in vivo quantitative measurement of capillary blood flow velocity governing skin metabolism functionally, i.e. microcirculation, is crucial to clarify the skin aging and to create skincare products. The purpose of this study is to visualize the tomographic velocity of red ...
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      Mentions: Osaka University
    8. Acute hydrops with a 180-degree massive edematous cavern demonstrated by three dimensional view of anterior segment optical coherence tomography in a patient with pellucid marginal corneal degeneration, a case report

      Acute hydrops with a 180-degree massive edematous cavern demonstrated by three dimensional view of anterior segment optical coherence tomography in a patient with pellucid marginal corneal degeneration, a case report
      Background Pellucid marginal corneal degeneration is a non-inflammatory disorder complicated by severe inferior corneal thinning. The central portion of the cornea, consequently, appears to protrude outwards, decreasing vision by means of an irregular stigmatism. Additionally, acute hydrops can occur in case of Descemets membrane rupture. Case presentation A 41-year-old Japanese woman presenting with severe visual loss in the left eye was examined and observed to have had full thickness corneal ...
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      Mentions: Osaka University
    9. Clinical features and visual function in a patient with Fish-eye disease: Quantitative measurements and optical coherence tomography

      Clinical features and visual function in a patient with Fish-eye disease: Quantitative measurements and optical coherence tomography
      Purpose We describe a case of fish-eye disease (FED) where the clinical features and visual function were investigated using anterior segment optical coherence tomography (OCT) and quantitative measurements. Observations A 36-year-old Japanese woman with FED presented with bilateral corneal opacities and visual complaints. Both contrast sensitivity and straylight were measured and OCT imaging was performed. Contrast sensitivity and straylight measurements revealed remarkably decreased visual function, despite good visual acuity. OCT ...
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      Mentions: Osaka University
    10. A Case of Retinal Detachment with Unique Optical Coherence Tomography Findings after Gamma Knife® Radiosurgery Treatment for Choroidal Melanoma

      A Case of Retinal Detachment with Unique Optical Coherence Tomography Findings after Gamma Knife® Radiosurgery Treatment for Choroidal Melanoma
      Purpose: To report a case of retinal detachment with unique optical coherence tomography (OCT) findings after Gamma Knife (GK; Elekta Instrument AB, Stockholm, Sweden) treatment for choroidal melanoma (CM). Case Report: A 48-year-old woman underwent GK therapy for CM in her right eye from the macula to the temporal side. While the tumor subsequently shrank, the patient developed radiation retinopathy, which was treated with laser photocoagulation. The tumor lesions later ...
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      Mentions: Osaka University
    11. RETINAL MICROVASCULATURE AND VISUAL ACUITY AFTER INTRAVITREAL AFLIBERCEPT IN EYES WITH CENTRAL RETINAL VEIN OCCLUSION: An Optical Coherence Tomography Angiography Study

      RETINAL MICROVASCULATURE AND VISUAL ACUITY AFTER INTRAVITREAL AFLIBERCEPT IN EYES WITH CENTRAL RETINAL VEIN OCCLUSION: An Optical Coherence Tomography Angiography Study
      Purpose: To investigate vascular perfusion and foveal avascular zone area in the superficial capillary plexus (SCP) and deep capillary plexus (DCP) after intravitreal aflibercept therapy in central retinal vein occlusion eyes and their association with best-corrected visual acuity. Methods: Thirty-five subjects with central retinal vein occlusion and macular edema were evaluated. After macular edema resolution following intravitreal aflibercept, subjects underwent optical coherence tomography angiography to measure SCP and DCP perfusion ...
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      Mentions: Osaka University
    12. Prevalence and Associated Factors of Segmentation Errors in the Peripapillary Retinal Nerve Fiber Layer and Macular Ganglion Cell Complex in Spectral-domain Optical Coherence Tomography Images

      Prevalence and Associated Factors of Segmentation Errors in the Peripapillary Retinal Nerve Fiber Layer and Macular Ganglion Cell Complex in Spectral-domain Optical Coherence Tomography Images
      Purpose: To determine the prevalence of errors in segmentation of the peripapillary retinal nerve fiber layer (RNFL) and macular ganglion cell complex (GCC) boundary in spectral-domain optical coherence tomography (SDOCT) images, and to identify factors associated with the errors. Patients and Methods: Peripapillary RNFL circle scans and macular three-dimensional scans of consecutive cases imaged with SDOCT (RS-3000 Advance; Nidek, Gamagori, Japan) were retrospectively reviewed by a glaucoma specialist. Images with ...
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    13. Retinal Microvasculature and Visual Acuity in Eyes With Branch Retinal Vein Occlusion: Imaging Analysis by Optical Coherence Tomography Angiography

      Retinal Microvasculature and Visual Acuity in Eyes With Branch Retinal Vein Occlusion: Imaging Analysis by Optical Coherence Tomography Angiography
      Purpose : To investigate microvascular changes in the superficial capillary plexus (SCP) and deep capillary plexus (DCP) in eyes with resolved branch retinal vein occlusion (BRVO) and their association with best-corrected visual acuity (BCVA). Methods : Eighty-five eyes (82 consecutive patients) with BRVO after resolution of the macular edema were retrospectively evaluated. All patients underwent optical coherence tomography angiography (OCTA) for assessment of microvascular changes, including capillary telangiectasia, microaneurysm, and disruption of ...
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    14. High frame-rate en face optical coherence tomography system using KTN optical beam deflector

      High frame-rate en face optical coherence tomography system using KTN optical beam deflector
      We developed high frame-rate en face optical coherence tomography (OCT) system using KTa 1-x Nb x O 3 (KTN) optical beam deflector. In the imaging system, the fast scanning was performed at 200 kHz by the KTN optical beam deflector, while the slow scanning was performed at 800 Hz by the galvanometer mirror. As a preliminary experiment, we succeeded in obtaining en face OCT images of human fingerprint with a ...
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  2. About Osaka University

    Osaka University

    Osaka University is a major national university located in Osaka, Japan. It is the sixth oldest university in Japan as the Osaka Prefectural Medical College, and formerly one of the Imperial Universities of Japan. Numerous prominent scientists worked at the Osaka University such as the Nobel Laureate in Physics Hideki Yukawa.  Also see Osaka University Medical School.  We aim to develop the research capability of our researchers and offer them comprehensive medical knowledge so that they can engage in research activities independently. We strive to foster extensively knowledgeable health care specialists with a flexible and methodical mind. We aim to train scientists and doctors who can meet present health care needs in the specialized field of nursing, as well as embrace the development of science. In addition, we endeavor to nurture scientists who are able to provide 21st Century intellectual leadership in the fields of Nursing and Medical Technology and Science.