1. Osaka University

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    1. Mentioned In 143 Articles

    2. Intraoperative optical coherence tomography observation with perfluorocarbon tamponade for subretinal membranes in proliferative vitreous retinopathy

      Intraoperative optical coherence tomography observation with perfluorocarbon tamponade for subretinal membranes in proliferative vitreous retinopathy
      Purpose: To report the efficacy of intraoperative optical coherence tomography (iOCT) in locating proliferative membranes or strands subretinally or preretinally during pars plana vitrectomy for proliferative vitreoretinopathy (PVR) or old rhegmatogenous retinal detachment. Methods: After removing the vitreous and apparent epiretinal membranes, vitreous fluid was exchanged for perfluorocarbon. Lesions of the retinal folds or persistently detached retinas, suspected to be subretinal membrane lesions, were examined using iOCT in three eyes ...
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      Mentions: Osaka University
    3. En Face OCT Detects Preretinal Abnormal Tissues Before and After Internal Limiting Membrane Peeling in Eyes with Macular Hole

      En Face OCT Detects Preretinal Abnormal Tissues Before and After Internal Limiting Membrane Peeling in Eyes with Macular Hole
      Purpose To assess preretinal abnormal tissue (PAT) using en face optical coherence tomography (OCT) in eyes with idiopathic macular holes (MHs). Design Retrospective, observational study. Participants MH patients who received 66-mm spectral-domain OCT scans. Methods PAT was detected by en face OCT images with a custom slab, defined with an anterior boundary of 6 m anterior to the internal limiting membrane (ILM) and a posterior boundary at 3 m posterior ...
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    4. Automated diagnosis of optical coherence tomography imaging on plaque vulnerability and its relation to clinical outcomes in coronary artery disease

      Automated diagnosis of optical coherence tomography imaging on plaque vulnerability and its relation to clinical outcomes in coronary artery disease
      This study sought to develop a deep learning-based diagnostic algorithm for plaque vulnerability by analyzing intravascular optical coherence tomography (OCT) images and to investigate the relation between AI-plaque vulnerability and clinical outcomes in patients with coronary artery disease (CAD). A total of 1791 study patients who underwent OCT examinations were recruited from a multicenter clinical database, and the OCT images were first labeled as either normal, a stable plaque, or ...
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    5. Microvascular Changes in the Cystic Lesion of Branch Retinal Vein Occlusion Imaged by Swept-Source Optical Coherence Tomography Angiography

      Microvascular Changes in the Cystic Lesion of Branch Retinal Vein Occlusion Imaged by Swept-Source Optical Coherence Tomography Angiography
      ...y in accordance with the World Medical Association Declaration of Helsinki. The institutional review board of Osaka University Hospital approved the study protocol (approval number: 09260), and informed consent was obtai...
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    6. Fourier analysis on irregular corneal astigmatism using optical coherence tomography in various severity stages of keratoconus

      Fourier analysis on irregular corneal astigmatism using optical coherence tomography in various severity stages of keratoconus
      Design : Prospective cross-sectional study Methods : The study included 126 eyes with clinical KC (50 KC without any corneal scar, 50 KC with anterior corneal scar, and 26 KC with posterior scar having a history of acute corneal hydrops), 50 with topographic KC (without clinical signs), 50 with pre-topographic KC (normal topography without clinical signs), and 50 controls. Corneal tomographic data were obtained using anterior segment optical coherence tomography (OCT). Fourier ...
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      Mentions: Osaka University
    7. Three-Dimensional Volume Calculation of Intrachoroidal Cavitation Using Deep-Learning-Based Noise Reduction of Optical Coherence Tomography

      Three-Dimensional Volume Calculation of Intrachoroidal Cavitation Using Deep-Learning-Based Noise Reduction of Optical Coherence Tomography
      Purpose: Intrachoroidal cavitations (ICCs) are peripapillary pathological lesions generally associated with high myopia that can cause visual field (VF) defects. The current study aimed to evaluate a three-dimensional (3D) volume parameter of ICCs segmented from volumetric swept-source optical coherence tomography (SS-OCT) images processed using deep learning (DL)-based noise reduction and to investigate its correlation with VF sensitivity. Methods: Thirteen eyes of 12 consecutive patients with peripapillary ICCs were enrolled ...
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    8. Treatment of Descemet's membrane detachment after primary Descemet's stripping automated endothelial keratoplasty during surgery using intraoperative optical coherence tomography

      Treatment of Descemet's membrane detachment after primary Descemet's stripping automated endothelial keratoplasty during surgery using intraoperative optical coherence tomography
      Purpose: To present a novel microscope-integrated optical coherence tomography (iOCT)-guided surgical technique wherein Descemet's membrane detachment (DMD), occurring during vitrectomy, was treated intraoperatively in a patient who had previously undergone Descemet's stripping automated endothelial keratoplasty (DSAEK). Observations: The surgical technique was performed on a 75-year-old man with a history of DSAEK to intraoperatively treat DMD, which occurred during vitrectomy in the left eye. A fine needle mounted ...
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      Mentions: Osaka University
    9. Analysis of optic disc tilt angle in intrapapillary hemorrhage adjacent to peripapillary subretinal hemorrhage using swept-source optical coherence tomography

      Analysis of optic disc tilt angle in intrapapillary hemorrhage adjacent to peripapillary subretinal hemorrhage using swept-source optical coherence tomography
      Purpose: To report findings on the tilt angle of optic nerve heads (ONHs) that developed intrapapillary hemorrhage with adjacent peripapillary subretinal hemorrhage (IHAPSH) using swept-source optical coherence tomography (SS-OCT). Observations: Five consecutive patients who presented with IHAPSH were reviewed retrospectively. We reviewed five consecutive eyes from the five patients, analyzed the optic tilt angle obtained from SS-OCT B-scans, and compared the results and other clinical characteristics. All patients had larger ...
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      Mentions: Osaka University
    10. Anterior chamber flare and ciliochoroidal detachment using flare photometry and anterior segment optical coherence tomography in acute lupus choroidopathy: A case report

      Anterior chamber flare and ciliochoroidal detachment using flare photometry and anterior segment optical coherence tomography in acute lupus choroidopathy: A case report
      Purpose: To report anterior chamber flare using laser flare photometry and ciliochoroidal detachment using anterior segment optical coherence tomography (AS-OCT) in a new onset acute lupus choroidopathy case. Observations: A 57-year-old woman with severe nephritis, pleural effusion, and ascites was referred to our ophthalmology clinic for rapid onset of bilateral blurred vision and eyelid swelling. She had a bilateral high-flared, shallow anterior chamber, and bilateral ciliochoroidal detachment, which was revealed ...
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      Mentions: Osaka University
    11. Diagnosis of Choroidal Disease With Deep Learning-Based Image Enhancement and Volumetric Quantification of Optical Coherence Tomography

      Diagnosis of Choroidal Disease With Deep Learning-Based Image Enhancement and Volumetric Quantification of Optical Coherence Tomography
      Purpose: The purpose of this study was to quantify choroidal vessels (CVs) in pathological eyes in three dimensions (3D) using optical coherence tomography (OCT) and a deep-learning analysis. Methods: A single-center retrospective study including 34 eyes of 34 patients (7 women and 27 men) with treatment-nave central serous chorioretinopathy (CSC) and 33 eyes of 17 patients (7 women and 10 men) with Vogt-Koyanagi-Harada disease (VKH) or sympathetic ophthalmitis (SO) were ...
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    12. Predicting 10-2 Visual Field From Optical Coherence Tomography in Glaucoma Using Deep Learning Corrected With 24-2/30-2 Visual Field

      Predicting 10-2 Visual Field From Optical Coherence Tomography in Glaucoma Using Deep Learning Corrected With 24-2/30-2 Visual Field
      Purpose: To investigate whether a correction based on a Humphrey field analyzer (HFA) 24-2/30-2 visual field (VF) can improve the prediction performance of a deep learning model to predict the HFA 10-2 VF test from macular optical coherence tomography (OCT) measurements. Methods: This is a multicenter, cross-sectional study. The training dataset comprised 493 eyes of 285 subjects (407, open-angle glaucoma [OAG]; 86, normative) who underwent HFA 10-2 testing and ...
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    13. Effects of Number of Stent Connectors on Mid-Term Vessel Healing and Stent Expansion Assessed by Optical Coherence Tomography

      Effects of Number of Stent Connectors on Mid-Term Vessel  Healing and Stent Expansion Assessed by Optical   Coherence Tomography
      Objective: Coronary stents generally consist of hoops and connectors. The number of connectors has been associated with longitudinal strength, flexibility, and deliverability of stents. However, a mid-term impact of number of connectors after stent implantation has been unclear. We sought to examine the effect of number of connectors on vessel healing and stent expansion using optical coherence tomogra - phy (OCT). Materials and Methods: The study included 39 patients with 46 ...
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      Mentions: Osaka University
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  2. About Osaka University

    Osaka University

    Osaka University is a major national university located in Osaka, Japan. It is the sixth oldest university in Japan as the Osaka Prefectural Medical College, and formerly one of the Imperial Universities of Japan. Numerous prominent scientists worked at the Osaka University such as the Nobel Laureate in Physics Hideki Yukawa.  Also see Osaka University Medical School.  We aim to develop the research capability of our researchers and offer them comprehensive medical knowledge so that they can engage in research activities independently. We strive to foster extensively knowledgeable health care specialists with a flexible and methodical mind. We aim to train scientists and doctors who can meet present health care needs in the specialized field of nursing, as well as embrace the development of science. In addition, we endeavor to nurture scientists who are able to provide 21st Century intellectual leadership in the fields of Nursing and Medical Technology and Science.