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Oregon Health & Science University
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Mentioned In 436 Articles
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Ruikang K. Wang. An effective digital frequency modulation approach to achieve directional blood flow imaging within microcirculations in tissue beds in vivo for optical microangiography is presented. The method only requires the system to capture one three-dimensional data set within which the interferograms are ... [Opt. Lett. 33, 1878-1880 (2008)]Read Full Article
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In vivo volumetric imaging of vascular perfusion within human retina and choroids with optical micro-angiography
Lin An, Ruikang K. Wang. Optical micro-angiography (OMAG), based on Fourier domain optical coherence tomography (OCT), is a recently developed imaging modality that provides dynamic blood flow imaging within microcirculation tissue beds in vivo. This paper presents its first application in imaging the blood circulations in ... [Opt. Express 16, 11438-11452 (2008)]Read Full Article -
Quantitative analysis on tongue inspection in traditional Chinese medicine using optical coherence tomography
...1, China Yonghong He Tsinghua University, Graduate School at Shenzhen, Shenzhen 518055, China Ruikang K. Wang Oregon Health and Science University, Department of Biomedical Engineering, Beaverton, Oregon 97006 Songhao Li...Read Full Article -
Evaluating optical properties of isolated biological scatterers from confocal and low-coherence images
In biomedical optics applications, the scattering of light by biological tissue is typically mimicked by embedding microparticles such as polystyrene microspheres or TiO within a non-scattering matrix. Such particles are well structured and give rise to uniform optical scattering properties. However ... [Proc. SPIE Int. Soc. Opt. Eng. 6870, 68700G (2008)] published Fri Feb 15, 2008.Read Full Article -
Measuring tissue optical properties in vivo using reflectance-mode confocal microscopy and OCT
The ability to separately measure the scattering coefficient ([mu] [cm]) and the anisotropy (g) is difficult, especially when measuring an in vivo site that can not be excised for bench-top measurements. The scattering properties ([mu] and g) can characterize the ultrastructure of a biological tissu ... [Proc. SPIE Int. Soc. Opt. Eng. 6864, 68640B (2008)] published Fri Feb 15, 2008.Read Full Article -
Reviewing the AC Cornea OCT
...athologic changes going on in the eye.” Mark Packer, M.D., clinical associate professor, Casey Eye Institute, Oregon Health & Science University, Portland, said the AC OCT sounds like a helpful tool. It’s normal that opt...Read Full Article -
In situ monitoring of localized shear stress and fluid flow within developing tissue constructs by Doppler optical coherence tomography
Yali Jia, Pierre O. Bagnaninchi, and Ruikang K. Wang Mechanical stimuli can be introduced to three dimensional (3D) cell cultures by use of perfusion bioreactor. Especially in musculoskeletal tissues, shear stress caused by fluid flow generally increase extra-cellular matrix (ECM) production and cell proliferation. The relationship between the shear s ... [Proc. SPIE Int. Soc. Opt. Eng. 6858, 68580G (2008)] published Wed Feb 6, 2008.Read Full Article -
Optically characterizing vascular tissue constructs made with soluble versus homogenized collagen
The ability of optical imaging techniques such as optical coherence tomography (OCT) to non-destructively characterize tissue-engineered constructs has generated enormous interest recently. We are testing the hypothesis that OCT data can be used to characterize the cellularity of collagen-based vasc ... [Proc. SPIE Int. Soc. Opt. Eng. 6858, 68580E (2008)] published Wed Feb 6, 2008.Read Full Article -
Algorithms for simulation of speckle (laser and otherwise)
The speckle phenomenon is observed in any coherent imaging modality such as synthetic aperture radar, optical coherence tomography, ultrasound, or any number of measurement schemes involving laser illumination. Quantitative interpretation of the data from such measurement schemes (whether imaging or non-imaging) often hinges on accurate knowledge of the statistical behavior of the speckle phenomenon. To complement experimental measurements, researchers often turn to computer simulation of the phenomenon of interest. Over ...Read Full Article -
Incision construction, architecture fight infection
...lear corneal incisions have become widespread. I. Howard Fine, M.D., clinical professor, Casey Eye Institute, Oregon Health & Science University, Portland, said many factors can affect infection rates but one area rises ...Read Full ArticleMentions: Oregon Health & Science University -
The copula: a tool for simulating speckle dynamics
Use of a copula for generating a sequence of correlated speckle patterns is introduced. The chief characteristic of this algorithm is that it generates a continuous speckle sequence with a specified evolution of the correlation and does so with just two arrays of random numbers. Thus, physically realistic temporally varying speckle patterns with proper first- and second-order statistics are easily realized. We illustrate use of the algorithm for generating sequences ...Read Full Article -
Digital phase stabilization to improve detection sensitivity for optical coherence tomography
...K 2 Cranfield Health, Cranfield University, Bedfordshire MK45 4DT, UK 3 Department of Biomedical Engineering, Oregon Health & Science University, Portland, OR 97239, USA E-mail: pete.tomlins@npl.co.uk and r.k.wang@bme.og...Read Full Article -
Statistics of local speckle contrast
Donald D. Duncan, Sean J. Kirkpatrick, Ruikang K. Wang. In describing the first-order properties of laser speckle under polarized illumination conditions, it is almost an article of faith that the contrast is unity. In many processing schemes, however, the contrast defined as the quotient of the standard deviation and the mean is calculated over a ... [J. Opt. Soc. Am. A 25, 9-15 (2008)]Read Full Article -
Quantitative temporal speckle contrast imaging for tissue mechanics
Sean J. Kirkpatrick, Donald D. Duncan, Ruikang K. Wang, Monica T. HindsWe demonstrate through a series of simulations that by parameterizing the temporal speckle contrast statistic from a sequence of translating speckle images on a number of experimental constants, the local temporal contrast can be used to quantitatively assess local motion, provided that the spatial ... [J. Opt. Soc. Am. A 24, 3728-3734 (2007)]Read Full Article -
Use of a scanner to modulate spatial interferograms for in vivo full-range Fourier-domain optical coherence tomography
Lin An, Ruikang K. WangWe report a new yet simple method to achieve full-range complex Fourier-domain optical coherence tomography (OCT) for in vivo imaging. The method utilizes a scanner that is dedicated for lateral scanning in the system to introduce a constant carrier frequency into the OCT spectral interferograms ... [Opt. Lett. 32, 3423-3425 (2007)]Read Full Article -
Myocardial revascularization-optical reflectance catheter and method
A myocardial revascularization device has a catheter suitable for use in a myocardial revascularization procedure, the catheter including an elongate body having a proximal end and a distal end, and tissue-ablating means housed at least partially within the catheter and capable of effectuating tissue ablation adjacent the distal end of the catheter. The device further has an optical reflectance fiber housed within the catheter and coupled to an optical reflectance ...Read Full ArticleMentions: Oregon Health & Science University
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About Oregon Health & Science University
Oregon Health & Science University (OHSU) is a public university in Oregon with a main campus, including three hospitals, in Portland and a smaller campus in Hillsboro. It was formed in 1974 as the University of Oregon Health Sciences Center, combining state dentistry, medicine, and nursing programs into a single center. It was renamed Oregon Health Sciences University in 1981 and took its current name in 2001, as part of a merger with the Oregon Graduate Institute of Science and Technology (OGI) in Hillsboro. In addition, the university has several partnership programs including a joint PharmD Pharmacy program with Oregon State University.
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